The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Negative impact of chronic obstructive pulmonary disease on the health-related quality of life of patients. Results of the EPIDEPOC study
Open accessAbstract
Background: COPD is currently the fourth cause of morbidity and mortality in the developed world. Patients with COPD experience a progressive deterioration and disability, which lead to a worsening in their health-related quality of life (HRQoL). The aim of this work is to assess the Health-Related Quality of Life (HRQoL) of patients with stable COPD followed in primary care and to identify possible predictors of disease. Methods: It is a multicenter, epidemiological, observational, descriptive study. Subjects of both sexes, older than 40 years and diagnosed of COPD at least 12 months before starting the study were included. Sociodemographic data, severity of disease, comorbidity, and use of health resources in the previous 12 months were collected. All patients were administered a generic quality-of-life questionnaire, the SF-12, that enables to calculate two scores, the physical (PCS-12) and the mental (MCS-12) component summary scores. Results: 10,711 patients were evaluated (75.6% men, 24.4% women), with a mean age of 67.1 years (SD 9.66). The mean value of FEV 1 was 35.9 ± 10.0%. Mean PCS-12 and MCS-12 scores were 36.0 ± 9.9 and 48.3 ± 10.9, respectively. Compared to the reference population, patients with COPD had a reduction of PCS-12, even in mild stages of the disease. The correlation with FEV 1 was higher for PCS-12 (r = 0.38) than for MCS-12 (r = 0.12). Predictors for both HRQoL components were sex, FEV 1, use of oxygen therapy, and number of visits to emergency rooms and hospital admissions. Other independent predictors of PCS-12 were age, body mass index and educational level. Conclusion: Patients with stable COPD show a reduction of their HRQoL, even in mild stages of the disease. The factors determining the HRQoL include sex, FEV 1, use of oxygen therapy, and number of visits to emergency rooms and hospital admissions.
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Cites
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“Some of them have found no relationship between HRQoL and the presence of respiratory failure [32,33].”
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“[41] have shown that HRQoL is a predictive factor independent from hospitalization and mortality in these patients.”
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Cited by
Buist, A. S., McBurnie, M. A., Vollmer, W. M., Gillespie, S., Burney, P., Mannino, D. M., Menezes, A. M., Sullivan, S. D., Lee, T. A., Weiss, K. B., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61377-4 · Cited by 2,366
Self management for patients with chronic obstructive pulmonary disease
Zwerink, M., Brusse-Keizer, M., van der Valk, P. D., Zielhuis, G. A., Monninkhof, E. M., van der Palen, J., Frith, P. A., & Effing, T. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002990.pub3 · Cited by 572
Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review
Iheanacho, I., Zhang, S., King, D., Rizzo, M., & Ismaila, A. S. (2020) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s234942 · Cited by 369
Lenferink, A., Brusse-Keizer, M., van der Valk, P. D., Frith, P. A., Zwerink, M., Monninkhof, E. M., van der Palen, J., & Effing, T. W. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011682.pub2 · Cited by 328
Health Related Quality of Life in Common Variable Immunodeficiency
Quinti, I., Di Pietro, C., Martini, H., Pesce, A. M., Lombardi, F., Baumghartner, M., Colantuono, S., Milito, C., & Tabolli, S. (2012) · Yonsei Medical Journal · doi:10.3349/ymj.2012.53.3.603 · Cited by 52
Metadata
- Authors
- Garrido, P. C., Díez, J. D. M., Gutiérrez, J. R., Centeno, A. M., Vázquez, E. G., de Miguel, Á. G., Carballo, M. G., & García, R. J.
- Venue
- Health and Quality of Life Outcomes
- Published
- 2006-05-23
- Volume
- 4
- Issue
- 1
- Pages
- 31-31
- ISSN
- 1477-7525 (ISSN-L)
- OpenAlex
- W2133284170
- Cited by
- 174
- References
- 8
- FWCI
- 8.59
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Negative impact of chronic obstructive pulmonary disease on the health-related quality of life of patients. Results of the EPIDEPOC study. https://app.cochat.ai/papers/10.1186/1477-7525-4-31
- The paper
- Garrido, P. C., Díez, J. D. M., Gutiérrez, J. R., Centeno, A. M., Vázquez, E. G., de Miguel, Á. G., Carballo, M. G., & García, R. J. (2006). Negative impact of chronic obstructive pulmonary disease on the health-related quality of life of patients. Results of the EPIDEPOC study. Health and Quality of Life Outcomes. https://doi.org/10.1186/1477-7525-4-31
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
