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Cited by 640

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics

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Revelli, Alberto, Piane, Luisa Delle, Casano, Simona, Molinari, Emanuela, Massobrio, Marco, Rinaudo, Paolo·2009·Reproductive Biology and Endocrinology
DOI 10.1186/1477-7827-7-40
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Abstract

The assessment of oocyte quality in human in vitro fertilization (IVF) is getting increasing attention from embryologists. Oocyte selection and the identification of the best oocytes, in fact, would help to limit embryo overproduction and to improve the results of oocyte cryostorage programs. Follicular fluid (FF) is easily available during oocyte pick-up and theorically represents an optimal source on non-invasive biochemical predictors of oocyte quality. Unfortunately, however, the studies aiming to find a good molecular predictor of oocyte quality in FF were not able to identify substances that could be used as reliable markers of oocyte competence to fertilization, embryo development and pregnancy. In the last years, a well definite trend toward passing from the research of single molecular markers to more complex techniques that study all metabolites of FF has been observed. The metabolomic approach is a powerful tool to study biochemical predictors of oocyte quality in FF, but its application in this area is still at the beginning. This review provides an overview of the current knowledge about the biochemical predictors of oocyte quality in FF, describing both the results coming from studies on single biochemical markers and those deriving from the most recent studies of metabolomics.

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Metadata

Authors
Revelli, A., Piane, L. D., Casano, S., Molinari, E., Massobrio, M., & Rinaudo, P.
Venue
Reproductive Biology and Endocrinology
Publisher
Springer Science and Business Media LLC
Published
2009-05-04
Volume
7
Issue
1
Pages
40-40
ISSN
1477-7827 (ISSN-L)
DOI
10.1186/1477-7827-7-40
OpenAlex
W1967090815
Cited by
640
References
94
FWCI
21.31
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics. https://app.cochat.ai/papers/10.1186/1477-7827-7-40
The paper
Revelli, A., Piane, L. D., Casano, S., Molinari, E., Massobrio, M., & Rinaudo, P. (2009). Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics. Reproductive Biology and Endocrinology. https://doi.org/10.1186/1477-7827-7-40

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.