Proteomic analysis of human vitreous humor

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Biomarkers in Diabetic Retinopathy

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Human vitreous in proliferative diabetic retinopathy: Characterization and translational implications

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Proteomic Biomarkers of Retinal Inflammation in Diabetic Retinopathy

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Lipid Nanoparticles as a Promising Drug Delivery Carrier for Topical Ocular Therapy—An Overview on Recent Advances

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MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy

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Application of lipid nanoparticles to ocular drug delivery

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Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management

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Vitreous humor analysis for the detection of xenobiotics in forensic toxicology: a review

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Quantitative Proteomics Analysis of Vitreous Humor from Diabetic Retinopathy Patients

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Proteomic Insight into the Molecular Function of the Vitreous

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Vitreous humor endogenous compounds analysis for post-mortem forensic investigation

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The Human Eye Proteome Project: Updates on an Emerging Proteome

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Vitreous Antioxidants, Degeneration, and Vitreo-Retinopathy: Exploring the Links

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Proteomic Analysis of the Bovine and Human Ciliary Zonule

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Minireview: Fibronectin in retinal disease

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Liquid Biopsy of Vitreous Reveals an Abundant Vesicle Population Consistent With the Size and Morphology of Exosomes

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Investigation of the global protein content from healthy human tears

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Importance of the Use of Oxidative Stress Biomarkers and Inflammatory Profile in Aqueous and Vitreous Humor in Diabetic Retinopathy

López-Contreras, A. K., Martínez-Ruíz, M. G., Olvera-Montaño, C., Robles-Rivera, R. R., Arévalo-Simental, D. E., Castellanos‐González, J. A., Hernández-Chávez, A., Huerta-Olvera, S. G., Cardona-Muñóz, E. G., & Rodríguez-Carrizález, A. D. (2020) · Antioxidants · doi:10.3390/antiox9090891 · Cited by 73

Updates on Biodegradable Formulations for Ocular Drug Delivery

Tsung, T., Chen, Y., & Lu, D. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030734 · Cited by 72

Employing Flow Cytometry to Extracellular Vesicles Sample Microvolume Analysis and Quality Control

Maia, J., Batista, S., Couto, N., Gregório, A. C., Bodo, C., Elzanowska, J., Moraes, M. C. S., & Costa‐Silva, B. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.593750 · Cited by 61

Characterization of Vitreous and Aqueous Proteome in Humans With Proliferative Diabetic Retinopathy and Its Clinical Correlation

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The Proteomic Landscape in the Vitreous of Patients With Age-Related and Diabetic Retinal Disease

Schori, C., Trachsel, C., Grossmann, J., Zygoula, I., Barthelmes, D., & Grimm, C. (2018) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.18-24122 · Cited by 57

Ocular Delivery of Therapeutic Proteins: A Review

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Vitreous humor in the pathologic scope: Insights from proteomic approaches

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Lipid-Based Nanocarriers as Topical Drug Delivery Systems for Intraocular Diseases

Navarro‐Partida, J., Castro‐Castañeda, C. R., Cruz-Pavlovich, F. J. S., Aceves-Franco, L. A., Ori-Guy, T., & Santos, A. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13050678 · Cited by 50

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy

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Proteome and Metabolome of Subretinal Fluid in Central Serous Chorioretinopathy and Rhegmatogenous Retinal Detachment: A Pilot Case Study

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The Quest of the Human Proteome and the Missing Proteins: Digging Deeper

Reddy, P. J., Ray, S., & Srivastava, S. (2015) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2015.0035 · Cited by 39

Protein Biomarkers in Uveitis

Bansal, R., & Gupta, A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.610428 · Cited by 37

Glaucoma: Management and Future Perspectives for Nanotechnology-Based Treatment Modalities

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Thermosensitive Nanocomposite Hydrogels for Intravitreal Delivery of Cefuroxime

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Self-Healing Thermosensitive Hydrogel for Sustained Release of Dexamethasone for Ocular Therapy

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Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice

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Concentration of microtubule associated protein tau (MAPT) in urine and saliva as a potential biomarker of traumatic brain injury in relationship with blood–brain barrier disruption in postmortem examination

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Anti-inflammatory Effect of Curcumin, Homotaurine, and Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy

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A novel and less invasive technique to assess cytokine profile of vitreous in patients of diabetic macular oedema

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Review of Intraocular Pharmacokinetics of Anti-Infectives Commonly Used in the Treatment of Infectious Endophthalmitis

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Investigation of Cas9 Antibodies in the Human Eye

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Identification of vitreous proteins in retinopathy of prematurity

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Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications

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Proteomic Study of Aqueous Humor and Its Application in the Treatment of Neovascular Glaucoma

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Vitreous Substitutes from Bench to the Operating Room in a Translational Approach: Review and Future Endeavors in Vitreoretinal Surgery

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Extracellular vesicles: an emerging player in retinal homeostasis

Chatterjee, A., & Singh, R. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1059141 · Cited by 26

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion

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Injectable alginate-based in situ self-healable transparent hydrogel as a vitreous substitute with a tamponading function

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Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick vitreous

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Ocular delivery of solid lipid nanoparticles

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iTRAQ Quantitative Proteomic Analysis of Vitreous from Patients with Retinal Detachment

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An Insight on the Timely Diagnosis of Diabetic Retinopathy Using Traditional and AI-Driven Approaches

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Replacing the vitreous body with hydrogels: Rationale and strategies

Schulz, A., Keskar, M., Swindle‐Reilly, K. E., Junge, V., Parikh, B. H., Su, X., Liu, Z., & Seah, I. Y. J. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101389 · Cited by 21

System-wide vitreous proteome dissection reveals impaired sheddase activity in diabetic retinopathy

Shaik, A. A., Qiu, B., Lai, S. L., Cheung, N., Tan, G. S. W., Neo, S. P., Tan, A., Cheung, C. M. G., Hong, W., Wong, T. Y., et al. (2022) · Theranostics · doi:10.7150/thno.72947 · Cited by 22

Integration of Vitreous Lipidomics and Metabolomics for Comprehensive Understanding of the Pathogenesis of Proliferative Diabetic Retinopathy

Fang, J., Wang, H., Niu, T., Shi, X., Xing, X., Qu, Y., Liu, Y., Liu, X., Xiao, Y., Dou, T., et al. (2023) · Journal of Proteome Research · doi:10.1021/acs.jproteome.3c00007 · Cited by 21

Choosing preclinical study models of diabetic retinopathy: key problems for consideration

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Plasma proteome profiling of freshwater and seawater life stages of rainbow trout (Oncorhynchus mykiss)

Morro, B., Doherty, M. K., Balseiro, P., Handeland, S. O., MacKenzie, S. A., Sveier, H., & Albalat, A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0227003 · Cited by 19

Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development

Hollmann, A. K., Dammann, I., Wemheuer, W. M., Wemheuer, W., Chilla, A., Tipold, A., Schulz‐Schaeffer, W., Beck, J., Schütz, E., & Brenig, B. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180665 · Cited by 18

Proteomic Analysis of Embryonic and Young Human Vitreous

Yee, K. M. P., Feener, E. P., Madigan, M. C., JACKSON, N. J., Gao, B., Ross‐Cisneros, F. N., Provis, J. M., Aiello, L. P., Sadun, A. A., & Sebag, J. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.15-16809 · Cited by 18

Differential Expression of Vitreous Proteins in Young and Mature New Zealand White Rabbits

Liu, Y., Bouhenni, R., Dufresne, C. P., Semba, R. D., & Edward, D. P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153560 · Cited by 17

Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition

Robinson, R. L., Youngblood, H. A., Iyer, H., Bloom, J., Lee, T. J., Chang, L. Y., Lukowski, Z. L., Zhi, W., Sharma, A. K., & Sharma, S. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.11.2 · Cited by 17

Recent updates on drug delivery approaches for improved ocular delivery with an insight into nanostructured drug delivery carriers for anterior and posterior segment disorders

Khan, S., Wai, C., & Ho, E. A. (2024) · Drug Delivery and Translational Research · doi:10.1007/s13346-024-01756-x · Cited by 18

Early posterior vitreous detachment is associated with LAMA5 dominant mutation

Napolitano, F., Iorio, V. D., Iorio, G. D., Melone, M. A. B., Gianfrancesco, F., Simonelli, F., Esposito, T., Testa, F., & Sampaolo, S. (2018) · Ophthalmic Genetics · doi:10.1080/13816810.2018.1558261 · Cited by 16

What Makes Cornea Immunologically Unique and Privileged? Mechanistic Clues from a High-Resolution Proteomic Landscape of the Human Cornea

Subbannayya, Y., Pinto, S. M., Mohanty, V., Dagamajalu, S., Prasad, T. S. K., & Murthy, K. R. (2020) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2019.0190 · Cited by 16

Analytical Strategy for MS-Based Thanatochemistry to Estimate Postmortem Interval

Aiello, D., Lucà, F., Siciliano, C., Frati, P., Fineschi, V., Rongo, R., & Napoli, A. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.0c01038 · Cited by 16

Proteomic analysis of differentially expressed proteins in vitreous humor of patients with retinoblastoma using iTRAQ-coupled ESI-MS/MS approach

Naru, J., Aggarwal, R., Singh, U., Mohanty, A. K., Bansal, D., Mangat, N. K., Kakkar, N., & Agnihotri, N. (2016) · Tumor Biology · doi:10.1007/s13277-016-5162-3 · Cited by 16

Confirmation of Luteinizing Hormone (LH) in Living Human Vitreous and the Effect of LH Receptor Reduction on Murine Electroretinogram

Movsas, T. Z., Wong, K. Y., Ober, M. D., Sigler, R. E., Lei, Z. M., & Muthusamy, A. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.05.049 · Cited by 16

Identification of unique proteins in vitreous fluid of patients with noninfectious uveitis

Kasudhan, K. S., Sarkar, S., Gupta, V., Gupta, A., & Chakraborti, A. (2018) · Acta Ophthalmologica · doi:10.1111/aos.13801 · Cited by 14

Immune Inhibitor A Metalloproteases Contribute to Virulence in Bacillus Endophthalmitis

Livingston, E. T., Mursalin, M. H., Coburn, P. S., Astley, R., Miller, F. C., Amayem, O., Lereclus, D., & Callegan, M. C. (2021) · Infection and Immunity · doi:10.1128/iai.00201-21 · Cited by 14

Proteomics

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Systematic review and meta-analysis of mass spectrometry proteomics applied to ocular fluids to assess potential biomarkers of age-related macular degeneration

Guo, H., Li, J., & Lu, P. (2023) · BMC Ophthalmology · doi:10.1186/s12886-023-03237-0 · Cited by 13

A Comprehensive Proteomics Analysis of the Human Iris Tissue: Ready to Embrace Postgenomics Precision Medicine in Ophthalmology?

Murthy, K. R., Dammalli, M., Pinto, S. M., Murthy, K. B., Nirujogi, R. S., Madugundu, A. K., Dey, G., Subbannayya, Y., Mishra, U. K., Nair, B. G., et al. (2016) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2016.0100 · Cited by 13

Proteomic profiling of human intraschisis cavity fluid

Sudha, D., Kohansal-Nodehi, M., Kovuri, P., Manda, S. S., Neriyanuri, S., Gopal, L., Bhende, P., Chidambaram, S., & Arunachalam, J. P. (2017) · Clinical Proteomics · doi:10.1186/s12014-017-9148-y · Cited by 13

Proteomic profile of vitreous in patients with tubercular uveitis

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Peptidomimetics Therapeutics for Retinal Disease

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