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Cited by 129Mental Health and PsychiatryPersonality Disorders and PsychopathologyPsychology and Mental Health

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DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions

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Nemeroff, Charles B, Weinberger, Daniel, Rutter, Michael, MacMillan, Harriet L, Bryant, Richard A, Wessely, Simon, Stein, Dan J, Pariante, Carmine M, Seemüller, Florian, Berk, Michael, Malhi, Gin S, Preisig, Martin, Brüne, Martin, Lysaker, Paul·2013·BMC Medicine
DOI 10.1186/1741-7015-11-202PMC PMC3846446
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Abstract

The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Medicine Editorial Board members who are experts in the field of psychiatry to discuss their personal views on how the changes in DSM-5 might affect clinical practice in their specific areas of psychiatric medicine. This article discusses the influence the DSM-5 may have on the diagnosis and treatment of autism, trauma-related and stressor-related disorders, obsessive-compulsive and related disorders, mood disorders (including major depression and bipolar disorders), and schizophrenia spectrum disorders.

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Charles B. Nemeroff is Leonard M. Miller Professor and Chairman of the Department of Psychiatry and Behavioral Sciences at University of Miami and Director of Center on Aging at Leonard M. Miller School of Medicine. His research interests include the biological basis of the major neuropsychiatric disorders, and he focuses on the use of genetic, neuroendocrine, neuroimaging, and neurochemical methods to comprehensively understand the pathophysiology of depression.
Charles B. Nemeroff is Leonard M. Miller Professor and Chairman of the Department of Psychiatry and Behavioral Sciences at University of Miami and Director of Center on Aging at Leonard M. Miller School of Medicine. His research interests include the biological basis of the major neuropsychiatric disorders, and he focuses on the use of genetic, neuroendocrine, neuroimaging, and neurochemical methods to comprehensively understand the pathophysiology of depression.CC BY · PubMed Central
Daniel Weinberger is Director and CEO of the Lieber Institute for Brain Development John Hopkins University School of Medicine, and Professor of Psychiatry, Neurology, and Neuroscience at the McKusick-Nathans Institute of Genetic Medicine. His research interests include the basic neurobiological and genetic mechanisms of neuropsychiatric disorders, especially schizophrenia.
Daniel Weinberger is Director and CEO of the Lieber Institute for Brain Development John Hopkins University School of Medicine, and Professor of Psychiatry, Neurology, and Neuroscience at the McKusick-Nathans Institute of Genetic Medicine. His research interests include the basic neurobiological and genetic mechanisms of neuropsychiatric disorders, especially schizophrenia.CC BY · PubMed Central
Michael Rutter is Professor of Developmental Psychopathology at the Institute of Psychiatry, Kings College London, and Consultant Psychiatrist at the Maudsley Hospital, London. He is founder of the Medical Research Council Child Psychiatry Research Unit and also the MRC Social, Genetic and Developmental Psychiatry Centre. His research interests include the genetics of autism, the development of diagnostic and screening measures for autism, antisocial behavior, studies of both school and family influences on children’s behavior, and the interplay between genetic and psychosocial risk factors.
Michael Rutter is Professor of Developmental Psychopathology at the Institute of Psychiatry, Kings College London, and Consultant Psychiatrist at the Maudsley Hospital, London. He is founder of the Medical Research Council Child Psychiatry Research Unit and also the MRC Social, Genetic and Developmental Psychiatry Centre. His research interests include the genetics of autism, the development of diagnostic and screening measures for autism, antisocial behavior, studies of both school and family influences on children’s behavior, and the interplay between genetic and psychosocial risk factors.CC BY · PubMed Central
Harriet L. MacMillan is Professor in the Departments of Psychiatry and Behavioural Neurosciences and in the Department of Pediatrics, Chedoke Health Chair in Child Studies and Acting Director of Offord Centre for Child Studies at McMaster University and McMaster Children’s Hospital/Hamilton Health Sciences. She is a pediatrician and child psychiatrist, and her research interests include research into family violence and trials of interventions aimed at prevention of child maltreatment and intimate partner violence. She is supported by the Chedoke Health Chair in Child Psychiatry.
Harriet L. MacMillan is Professor in the Departments of Psychiatry and Behavioural Neurosciences and in the Department of Pediatrics, Chedoke Health Chair in Child Studies and Acting Director of Offord Centre for Child Studies at McMaster University and McMaster Children’s Hospital/Hamilton Health Sciences. She is a pediatrician and child psychiatrist, and her research interests include research into family violence and trials of interventions aimed at prevention of child maltreatment and intimate partner violence. She is supported by the Chedoke Health Chair in Child Psychiatry.CC BY · PubMed Central
Richard Bryant is Scientia Professor at School of Psychology, University of New South Wales. His research interests include assessment, mechanisms, and treatment of post-traumatic stress disorder and anxiety. He served on the DSM-5 PTSD/Trauma/Dissociative Work Group and the ICD-11 Working Party on Stress-related Disorders.
Richard Bryant is Scientia Professor at School of Psychology, University of New South Wales. His research interests include assessment, mechanisms, and treatment of post-traumatic stress disorder and anxiety. He served on the DSM-5 PTSD/Trauma/Dissociative Work Group and the ICD-11 Working Party on Stress-related Disorders.CC BY · PubMed Central
Simon Wessely is Consultant Psychiatrist at King’s College Hospital and the Maudsley Hospital, and Professor of Psychological Medicine at Kings College London, and Vice Dean at Institute of Psychiatry, Kings College London. His current research interests include clinical epidemiology, psychiatric injury, and military health. He also served on the ICD-11 Working Party on Stress related Disorders.
Simon Wessely is Consultant Psychiatrist at King’s College Hospital and the Maudsley Hospital, and Professor of Psychological Medicine at Kings College London, and Vice Dean at Institute of Psychiatry, Kings College London. His current research interests include clinical epidemiology, psychiatric injury, and military health. He also served on the ICD-11 Working Party on Stress related Disorders.CC BY · PubMed Central
Dan J. Stein is Professor and Chair of the Dept of Psychiatry and Mental Health at the University of Cape Town, and Director of the MRC Unit on Anxiety and Stress Disorders. His research interests include the psychobiology and management of the anxiety, obsessive-compulsive and related disorders, and traumatic and stress disorders. He also served as Chair of the DSM-5 Sub-work Group on Obsessive-Compulsive Spectrum Disorders.
Dan J. Stein is Professor and Chair of the Dept of Psychiatry and Mental Health at the University of Cape Town, and Director of the MRC Unit on Anxiety and Stress Disorders. His research interests include the psychobiology and management of the anxiety, obsessive-compulsive and related disorders, and traumatic and stress disorders. He also served as Chair of the DSM-5 Sub-work Group on Obsessive-Compulsive Spectrum Disorders.CC BY · PubMed Central
Carmine M. Pariante is Professor of Biological Psychiatry at Institute of Psychiatry, Kings College London. His research focuses on the biological effects of stress, the pathogenesis of depression, and the molecular mechanisms of antidepressant drugs.
Carmine M. Pariante is Professor of Biological Psychiatry at Institute of Psychiatry, Kings College London. His research focuses on the biological effects of stress, the pathogenesis of depression, and the molecular mechanisms of antidepressant drugs.CC BY · PubMed Central
Florian Seemüller is consultant for psychiatry at the Department of Psychiatry at the Ludwig-Maximilians-University Munich. His research interests focuses on suicide research, bipolar disorder, and the systematic, course-related, and clinically oriented evaluation of longitudinal data from patients with depressive disorders and disorders among patients with schizophrenia.
Florian Seemüller is consultant for psychiatry at the Department of Psychiatry at the Ludwig-Maximilians-University Munich. His research interests focuses on suicide research, bipolar disorder, and the systematic, course-related, and clinically oriented evaluation of longitudinal data from patients with depressive disorders and disorders among patients with schizophrenia.CC BY · PubMed Central
Michael Berk is Alfred Deakin Professor of Psychiatry in the School of Medicine, Deakin University where he heads the IMPACT Strategic Research Centre. He is also a Professorial Research Fellow at the University of Melbourne in the Department of Psychiatry, the Centre for Youth Mental Health, Orygen Research Centre, and the Florey Institute for Neuroscience and Mental Health. His predominant interests include risk factors for and prevention of mood disorders, and the discovery and implementation of novel therapies.
Michael Berk is Alfred Deakin Professor of Psychiatry in the School of Medicine, Deakin University where he heads the IMPACT Strategic Research Centre. He is also a Professorial Research Fellow at the University of Melbourne in the Department of Psychiatry, the Centre for Youth Mental Health, Orygen Research Centre, and the Florey Institute for Neuroscience and Mental Health. His predominant interests include risk factors for and prevention of mood disorders, and the discovery and implementation of novel therapies.CC BY · PubMed Central
Gin S Malhi is Head of the Department of Psychiatry, Sydney Medical School, University of Sydney, and also Director of the CADE Clinic, Royal North Shore Hospital. His research interests include the use of clinical and neuropsychological assessments in conjunction with neurobiological probes to investigate the neural basis of mood disorders.
Gin S Malhi is Head of the Department of Psychiatry, Sydney Medical School, University of Sydney, and also Director of the CADE Clinic, Royal North Shore Hospital. His research interests include the use of clinical and neuropsychological assessments in conjunction with neurobiological probes to investigate the neural basis of mood disorders.CC BY · PubMed Central
Martin Preisig is Professor at the Department of Psychiatry of the University Hospital of Lausanne, Switzerland, and head of the Psychiatric Epidemiology and Psychopathology Research Unit. His main scientific interests include the familial aggregation and genetic determinants of psychiatric disorders, and the association between psychiatric disorders and cardiovascular risk factors.
Martin Preisig is Professor at the Department of Psychiatry of the University Hospital of Lausanne, Switzerland, and head of the Psychiatric Epidemiology and Psychopathology Research Unit. His main scientific interests include the familial aggregation and genetic determinants of psychiatric disorders, and the association between psychiatric disorders and cardiovascular risk factors.CC BY · PubMed Central
Martin Brüne is Professor of Cognitive Neuropsychiatry and Psychiatric Preventive Medicine at the LWL University Hospital of Psychiatry, Ruhr-University Bochum, Germany. His main research interest is social cognition in patients with schizophrenia, and the study of psychopathology from an evolutionary perspective.
Martin Brüne is Professor of Cognitive Neuropsychiatry and Psychiatric Preventive Medicine at the LWL University Hospital of Psychiatry, Ruhr-University Bochum, Germany. His main research interest is social cognition in patients with schizophrenia, and the study of psychopathology from an evolutionary perspective.CC BY · PubMed Central
Paul Lysaker is Professor of Clinical Psychology in Clinical Psychiatry at Indiana University School of Medicine, and Clinical Psychologist and Clinical Supervisor at the Psychiatric Rehabilitation and Recovery Center at the Roudebush VA Medical Center. His research interests include understanding the roots of psychosocial dysfunction in individuals with schizophrenia, and the development of new rehabilitative and psychotherapeutically based interventions.
Paul Lysaker is Professor of Clinical Psychology in Clinical Psychiatry at Indiana University School of Medicine, and Clinical Psychologist and Clinical Supervisor at the Psychiatric Rehabilitation and Recovery Center at the Roudebush VA Medical Center. His research interests include understanding the roots of psychosocial dysfunction in individuals with schizophrenia, and the development of new rehabilitative and psychotherapeutically based interventions.CC BY · PubMed Central

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Research works printed but not linked: 5

  1. American Psychiatric Association: Highlights of Changes from DSM-IV-TR to DSM-5. 2013, Arlington, VA: American Psychiatric Association
  2. Yung A, Phillips LJ, McGorry PD, et al: Comprehensive Assessment of At-Risk Mental States (CAARMS). 2001, Melbourne: PACE Clinic, University of Melbourne
  3. Fabrega H: Phylogenetic and Cultural Basis of Mental Illness. 2002, New Brunswick: Rutgers University Press
  4. Slade M: Personal Recovery and Mental Illness: A Guide for Mental Health Professionals. 2009, NY, NY: Cambridge University Press · DOI · Paper page
  5. Lysaker PH, Bob P, Pec O, Hamm J, Kukla M, Vohs J, Popolo R, Salvatore G, Dimaggio G: Metacognition as a link which connects brain to behavior in schizophrenia. Translational Neurosci. In press

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Metadata

Authors
Nemeroff, C. B., Weinberger, D., Rutter, M., MacMillan, H. L., Bryant, R. A., Wessely, S., Stein, D. J., Pariante, C. M., Seemüller, F., Berk, M., Malhi, G. S., Preisig, M., Brüne, M., & Lysaker, P.
Affiliations
  • University of Miami (US)
  • Johns Hopkins University (US)
  • King's College London (GB)
  • McMaster University (CA)
  • UNSW Sydney (AU)
  • University of Cape Town (ZA)
  • Ludwig-Maximilians-Universität München (DE)
  • Barwon Health (AU)
  • The University of Sydney (AU)
  • Centre Hospitalier Universitaire Vaudois (CH)
  • University Hospitals of the Ruhr-University of Bochum (DE)
  • Richard L. Roudebush VA Medical Center (US)
ORCID
Venue
BMC Medicine
Publisher
Springer Science and Business Media LLC
Published
2013-09-12
Volume
11
Issue
1
Pages
202-202
ISSN
1741-7015 (ISSN-L)
DOI
10.1186/1741-7015-11-202
PMC
PMC3846446
OpenAlex
W2032302431
Cited by
128
References
72
Citations by year
2026: 4 · 2025: 2 · 2024: 15 · 2023: 12 · 2022: 7 · 2021: 4 · 2020: 16 · 2019: 7 · 2018: 8 · 2017: 12 · 2016: 6 · 2015: 12 · 2014: 22 · 2013: 1
FWCI
99.77
Type
journal article
Language
en
Open access
Licence
Locations
  • BMC Medicine (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • SERVAL (Université de Lausanne) (publishedVersion, other-oa)
  • IUScholarWorks (Indiana University) (submittedVersion, cc-by)
  • IRIS (submittedVersion)
  • Research Portal (King's College London) (submittedVersion, other-oa)
  • Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
  • Minerva Access (University of Melbourne) (submittedVersion, cc-by)
  • Open University of Cape Town (University of Cape Town) (submittedVersion, cc-by)
Topics
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Clinical Psychology › Psychology and Mental Health
Keywords
DSM-5, psychiatric diagnosis, diagnostic classification, autism spectrum disorder, obsessive-compulsive and related disorders, mood disorders, major depressive disorder, bipolar disorder, schizophrenia spectrum disorders, clinical practice, psychiatrists' perspectives
MeSH terms
Humans, Psychiatry, Diagnostic and Statistical Manual of Mental Disorders

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