Cited by 32Health Policy Implementation ScienceMalaria Research and ControlBehavioral Health and Interventions

The development of effective behaviour change interventions to support the use of malaria rapid diagnostic tests by Tanzanian clinicians

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Chandler, Clare I R, Meta, Judith, Ponzo, Célia, Nasuwa, Fortunata, Kessy, John, Mbakilwa, Hilda, Haaland, Ane, Reyburn, Hugh·2014·Implementation Science

Abstract

BACKGROUND: Parasitological confirmation is now recommended for all cases of suspected malaria. The roll-out of rapid diagnostic tests (RDTs) is hoped to enable this goal in low resource settings through point of care testing. However, simply making RDTs available has not led to high uptake of the tests or adherence to results by clinicians, with malaria continuing to be overdiagnosed in many settings. We undertook to design an evidence-based intervention package that would be sufficient to support the introduction of RDTs at dispensaries in Tanzania, to be evaluated through the Targeting Artemisinin Combination Therapy (TACT) cluster randomised controlled trial. METHODS: We describe five steps in our intervention design: formative research, review of existing evidence and theory, a workshop to define the intervention approach and content and results of formative research, engagement with behaviour change theory and literature, detailed design of intervention materials and piloting and pretesting of intervention materials. This involved fieldwork with a total of 19 health workers and 212 community members in northeast Tanzania. RESULTS: The formative research suggested that RDTs were a potential source of conflict in the health worker-patient interaction, but that health workers used various techniques to resolve this, including provision of antimalarial drugs for RDT-negative patients. Our reviews showed that evidence was mixed regarding the effectiveness of different methods and theories to support change in prescribing practice. Our design process is presented, drawing from this collective evidence. We describe the final TACT intervention package (including interactive small group workshops, feedback text messages, motivational text messages and patient information leaflets and posters) in terms of its programme theory and implementation theory. CONCLUSIONS: Our study suggests that evidence-based design of complex interventions is possible. The use of formative research to understand malaria overdiagnosis in context was central to the design of the intervention as well as empirical research to test materials and methods prior to implementation. The TACT interventions may be appropriate for other settings where clinicians face similar challenges with malaria diagnostics. TRIAL REGISTRATION: NCT01292707.

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  • Among the papers that covered barrier identification, the methods used included observations, interviews and/or focus groups, surveys, literature reviews, structured reflection by researchers, job analysis and expert consensus, and predictive studies to identify factors influencing behaviour.

    “In the papers where barrier identification was covered, the methods included observations, interviews and/or focus groups [14, 18, 30–32], surveys [32], literature reviews [24], structured reflection by the researchers [32], job analysis and expert consensus [18], and undertaking a predictive study to identify factors influencing the behaviour [28].”

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  1. World Health Organisation Guidelines for the Treatment of Malaria 2010 2 Geneva Available online at http://www.who.int/malaria/publications/atoz/9789241547925/en/index.html 25473692
  2. Haaland A Moloney J Mshana C Instructions on use of AMs which give users visual logical reasons to finish course, may influence adherence understanding of connection between taking full course of treatment and clearance of malaria parasites in Tanzania and Uganda (poster) Multilateral Initiative on Malaria Conference 2009 Nairobi
  3. Ross-Degnan D Laing R Santoso B Ofori-Adjei D Lamoureux C Hogerzeil H Improving pharmaceutical use in primary care in developing counties: a critical review of experience and lack of experience Presented at the International Conference on Improving Use of Medicines 1997 Chiang Mai, Thailand
  4. Haaland A Sopiene R Kuksa L Skrastina I Biraua E Skerbiene A Gajauskiene V Kaupiene J Bielskiene V Using guided self-observation and reflection Increase motivation to learn communication skills (poster) EACH (European Association for Communication in Health) conference 2010 Verona, Italy

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Authors
Chandler, C. I. R., Meta, J., Ponzo, C., Nasuwa, F., Kessy, J., Mbakilwa, H., Haaland, A., & Reyburn, H.
Affiliations
  • London School of Hygiene & Tropical Medicine (GB)
  • Kilimanjaro Christian Medical Centre (TZ)
  • Ministry of Health (SC)
  • University of Oslo (NO)
Corresponding author
Chandler, Clare I R
Venue
Implementation Science
Published
2014-06-26
Volume
9
Issue
1
Pages
83-83
ISSN
1748-5908 (ISSN-L)
OpenAlex
W2132613714
Cited by
32
References
53
Citations by year
2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 6 · 2016: 6 · 2015: 6
FWCI
10.84
Type
journal article
Language
en
Open access
Locations
  • Implementation Science (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
Funders
Bill and Melinda Gates Foundation
Topics
  • Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
  • Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
Keywords
malaria rapid diagnostic tests, behaviour change interventions, complex intervention design, prescribing patterns, artemisinin-based combination therapy, small group workshops, patient information leaflets, Tanzania
MeSH terms
Education, Humans, Malaria, Practice Patterns, Physicians', Reagent Kits, Diagnostic, Tanzania, Technology Transfer, Antimanic Agents

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