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Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study
Open accessAbstract
The CIAO Study ("Complicated Intra-Abdominal infection Observational" Study) is a multicenter investigation performed in 68 medical institutions throughout Europe over the course of a 6-month observational period (January-June 2012).Patients with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study.2,152 patients with a mean age of 53.8 years (range: 4-98 years) were enrolled in the study. 46.3% of the patients were women and 53.7% were men. Intraperitoneal specimens were collected from 62.2% of the enrolled patients, and from these samples, a variety of microorganisms were collectively identified.The overall mortality rate was 7.5% (163/2.152).According to multivariate analysis of the compiled data, several criteria were found to be independent variables predictive of patient mortality, including patient age, the presence of an intestinal non-appendicular source of infection (colonic non-diverticular perforation, complicated diverticulitis, small bowel perforation), a delayed initial intervention (a delay exceeding 24 hours), sepsis and septic shock in the immediate post-operative period, and ICU admission.Given the sweeping geographical distribution of the participating medical centers, the CIAO Study gives an accurate description of the epidemiological, clinical, microbiological, and treatment profiles of complicated intra-abdominal infections (IAIs) throughout Europe.
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Cited by
Pisano, M., Allievi, N., Gurusamy, K., Borzellino, G., Cimbanassi, S., Boerna, D., Coccolini, F., Tufo, A., Di Martino, M., Leung, J., et al. (2020) · World Journal of Emergency Surgery · doi:10.1186/s13017-020-00336-x · Cited by 581
Self-citationThe Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection
Mazuski, J. E., Tessier, J. M., May, A. K., Sawyer, R. G., Nadler, E. P., Rosengart, M. R., Chang, P. K., O'Neill, P. J., Mollen, K. P., Huston, J. M., et al. (2017) · Surgical Infections · doi:10.1089/sur.2016.261 · Cited by 573
Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study
Sartelli, M., Catena, F., Ansaloni, L., Coccolini, F., Corbella, D., Moore, E. E., Malangoni, M., Velmahos, G., Coimbra, R., Koike, K., et al. (2014) · World Journal of Emergency Surgery · doi:10.1186/1749-7922-9-37 · Cited by 313
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Metadata
- Authors
- Sartelli, M., Catena, F., Ansaloni, L., Leppaniemi, A., Taviloglu, K., van Goor, H., Viale, P., Lazzareschi, D., Coccolini, F., Corbella, D., de Werra, C., Marrelli, D., Colizza, S., Scibè, R., Alis, H., Torer, N., Navarro, S., Sakakushev, B., Massalou, D., Augustin, G., Catani, M., Kauhanen, S., Pletinckx, P., Kenig, J., Di Saverio, S., Jovine, E., Guercioni, G., Skrovina, M., Diaz-Nieto, R., Ferrero, A., Rausei, S., Laine, S., Major, P., Angst, E., Pittet, O., Herych, I., Agresta, F., Vettoretto, N., Poiasina, E., Tepp, J., Weiss, G., Vasquez, G., Vladov, N., Tranà, C., Delibegovic, S., Dziki, A., Giraudo, G., Pereira, J., Tzerbinis, H., van Dellen, D., Hutan, M., Vereczkei, A., Krasniqi, A., Seretis, C., Mesina, C., Rems, M., Campanile, F., Coletta, P., Uotila-Nieminen, M., Dente, M., Bouliaris, K., Lasithiotakis, K., Khokha, V., Zivanovic, D., Smirnov, D., Marinis, A., Negoi, I., Ney, L., Bini, R., Leon, M., Aloia, S., Huchon, C., Moldovanu, R., de Melo, R., Giakoustidis, D., Ioannidis, O., Cucchi, M., Pintar, T., Krivokapic, Z., & Petrovic, J.
- Venue
- World Journal of Emergency Surgery
- Published
- 2012
- Volume
- 7
- Issue
- 1
- Pages
- 36
- ISSN
- 1749-7922 (ISSN-L)
- OpenAlex
- W2148895037
- Cited by
- 162
- References
- 0
- FWCI
- 6.40
- Type
- journal article
- Language
- en
- Open access
- gold
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- Sartelli, M., Catena, F., Ansaloni, L., Leppaniemi, A., Taviloglu, K., van Goor, H., Viale, P., Lazzareschi, D., Coccolini, F., Corbella, D., de Werra, C., Marrelli, D., Colizza, S., Scibè, R., Alis, H., Torer, N., Navarro, S., Sakakushev, B., Massalou, D., . . . Petrovic, J. (2012). Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study. World Journal of Emergency Surgery. https://doi.org/10.1186/1749-7922-7-36
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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