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Pharmacology of ginsenosides: a literature review
Open accessAbstract
The therapeutic potential of ginseng has been studied extensively, and ginsenosides, the active components of ginseng, are shown to be involved in modulating multiple physiological activities. This article will review the structure, systemic transformation and bioavailability of ginsenosides before illustration on how these molecules exert their functions via interactions with steroidal receptors. The multiple biological actions make ginsenosides as important resources for developing new modalities. Yet, low bioavailability of ginsenoside is one of the major hurdles needs to be overcome to advance its use in clinical settings.
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Cites
Naturally Occurring Insecticides
Jacobson, M., Crosby, D. G., & FORGASH, A. J. (1972) · Soil Science · doi:10.1097/00010694-197205000-00015 · Cited by 543
Cited by
Panossian, A. G., Efferth, T., Shikov, A. N., Pozharitskaya, O. N., Kuchta, K., Mukherjee, P. K., Banerjee, S., Heinrich, M., Wu, W., Guo, D., et al. (2021) · Medicinal Research Reviews · doi:10.1002/med.21743 · Cited by 347
Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity
Yang, W.-Z., Hu, Y., Wu, W.-Y., Ye, M., & Guo, D.-A. (2014) · Phytochemistry · doi:10.1016/j.phytochem.2014.07.012 · Cited by 342
Role of p38/MAPKs in Alzheimer's Disease: Implications for Amyloid Beta Toxicity Targeted Therapy
Kheiri, G., Dolatshahi, M., Rahmani, F., & Rezaei, N. (2018) · Reviews in the Neurosciences · doi:10.1515/revneuro-2018-0008 · Cited by 211
Panossian, A. (2017) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13399 · Cited by 156
Adaptogenic herb ginseng (Panax) as medical food: Status quo and future prospects
Patel, S., & Rauf, A. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.11.112 · Cited by 126
Metadata
- Authors
- Leung, K., & Wong, A.
- Venue
- Chinese Medicine
- Published
- 2010
- Volume
- 5
- Issue
- 1
- Pages
- 20
- ISSN
- 1749-8546 (ISSN-L)
- OpenAlex
- W2047726392
- Cited by
- 537
- References
- 1
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.