CoChat
Sign Up
Cited by 25

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Inverse correlation between serum interleukin-6 and iron levels among Japanese adults: a cross-sectional study

Nakagawa, Hiroko, Tamura, Takashi, Mitsuda, Yoko, Goto, Yasuyuki, Kamiya, Yoshikazu, Kondo, Takaaki, Wakai, Kenji, Hamajima, Nobuyuki·2014·BMC Hematology
DOI 10.1186/2052-1839-14-6PMC PMC3974032
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1186/2052-1839-14-6

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • A clinical study demonstrated an inverse correlation between low serum iron and high serum IL-6 levels.

    “Moreover, a clinical study demonstrated an inverse correlation between low serum iron and high serum IL-6 levels (Nakagawa et al., 2014”

    From Targeting Interleukin-6 Signaling in Clinic (2019) · cites this paper as Nakagawa et al., 2014

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 27

  1. Hirano T, Akira S, Taga T, Kishimoto T: Biological and clinical aspects of interleukin 6. Immunol Today. 1990, 11: 443-449. · DOI
  2. Horii Y, Muraguchi A, Iwano M, Matsuda T, Hirayama T, Yamada H, Fujii Y, Dohi K, Ishikawa H, Ohmoto Y, Yoshizaki K, Hirano T, Kishimoto T: Involvement of IL-6 in mesangial proliferative glomerulonephritis. J Immunol. 1989, 15: 3949-3955. · DOI
  3. Raj DS: Role of interleukin-6 in the anemia of chronic disease. Semin Arthritis Rheum. 2009, 38: 382-388. 10.1016/j.semarthrit.2008.01.006. · DOI
  4. Kishimoto T, Akira S, Taga T: Interleukin-6 and its receptor: a paradigm for cytokines. Science. 1992, 258: 593-597. 10.1126/science.1411569. · DOI · Paper page
  5. Nishimoto N, Kishimoto T, Yoshizaki K: Anti-interleukin 6 receptor antibody treatment in rheumatic disease. Ann Rheum Dis. 2000, 59 (Suppl 1): i21-i127. · DOI
  6. Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S: Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA. 2001, 98: 8780-8785. 10.1073/pnas.151179498. · DOI · Paper page
  7. Ganz T, Nemeth E: Hepcidin and disorders of iron metabolism. Annu Rev Med. 2011, 62: 347-360. 10.1146/annurev-med-050109-142444. · DOI · Paper page
  8. Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T: Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003, 101: 2461-2463. 10.1182/blood-2002-10-3235. · DOI · Paper page
  9. Nieken J, Mulder NH, Buter J, Vellenga E, Limburg PC, Piers DA, de Vries EG: Recombinant human interleukin-6 induces a rapid and reversible anemia in cancer patients. Blood. 1995, 86: 900-905. · DOI · Paper page
  10. Kemna E, Pickkers P, Nemeth E, van der Hoeven H, Swinkels D: Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood. 2005, 106: 1864-1866. 10.1182/blood-2005-03-1159. · DOI · Paper page
  11. Caliskan Y, Yelken B, Ozkok A, Gorgulu N, Yazici H, Telci A, Yildiz A: Lower serum prohepcidin levels associated with lower iron and erythropoietin requirements in hemodialysis patients with chronic hepatitis C. BMC Nephrol. 2012, 13: 56-10.1186/1471-2369-13-56. doi:10.1186/1471-2369-13-56 · DOI
  12. Kuo HC, Yang YL, Chuang JH, Tiao MM, Yu HR, Huang LT, Yang KD, Chang WC, Lee CP, Huang YH: Inflammation-induced hepcidin is associated with the development of anemia and coronary artery lesions in Kawasaki disease. J Clin Immunol. 2012, 32: 746-752. 10.1007/s10875-012-9668-1. · DOI
  13. Maruna P, Vokurka M, Lindner J: Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy. Physiol Res. 2011, 60: 493-502. · DOI
  14. Robson-Ansley P, Walshe I, Ward D: The effect of carbohydrate ingestion on plasma interleukin-6, hepcidin and iron concentrations following prolonged exercise. Cytokine. 2011, 53: 196-200. 10.1016/j.cyto.2010.10.001. · DOI
  15. Basseri RJ, Nemeth E, Vassilaki ME, Basseri B, Enayati P, Shaye O, Bourikas LA, Ganz T, Papadakis KA: Hepcidin is a key mediator of anemia of inflammation in Crohn’s disease. J Crohns Colitis. 2013, 7: e286-e291. 10.1016/j.crohns.2012.10.013. · DOI
  16. Ganz T: Hepcidin and iron regulation, 10 years later. Blood. 2011, 117: 4425-4433. 10.1182/blood-2011-01-258467. · DOI · Paper page
  17. Falkensammer CE, Thurnher M, Leonhartsberger N, Ramoner R: C-reactive protein is a strong predictor for anaemia in renal cell carcinoma: role of IL-6 in overall survival. BJU Int. 2011, 107: 1893-1898. 10.1111/j.1464-410X.2010.09817.x. · DOI
  18. Eleftheriadis T, Pissas G, Remoundou M, Filippidis G, Antoniadi G, Oustampasidou N, Liakopoulos V, Stefanidis I: Ferroportin in monocytes of hemodialysis patients and its associations with hepcidin, inflammation, markers of iron status and resistance to erythropoietin. Int Urol Nephrol. 2013, [Epub ahead of print]
  19. Eguchi A, Mochizuki T, Tsukada M, Kataoka K, Hamaguchi Y, Oguni S, Nitta K, Tsuchiya K: Serum hepcidin levels and reticulocyte hemoglobin concentrations as indicators of the iron status of peritoneal dialysis patients. Int J Nephrol. 2012, 2012: 239476-doi:10.1155/2012/239476. Epub 2012 Nov 1 · DOI
  20. Schwarz P, Kübler JA, Strnad P, Müller K, Barth TF, Gerloff A, Feick P, Peyssonnaux C, Vaulont S, Adler G, Kulaksiz H: Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection. Gut. 2012, 61: 193-201. 10.1136/gut.2011.241208. · DOI
  21. Lee SY, Song EY, Yun YM, Yoon SY, Cho YH, Kim SY, Lee MH: Serum prohepcidin levels in Helicobacter pylori infected patients with iron deficiency anemia. Korean J Intern Med. 2010, 25: 195-200. 10.3904/kjim.2010.25.2.195. · DOI
  22. Cherian S, Forbes DA, Cook AG, Sanfilippo FM, Kemna EH, Swinkels DW, Burgner DP: An insight into the relationships between hepcidin, anemia, infections and inflammatory cytokines in pediatric refugees: a cross-sectional study. PLoS One. 2008, 3: e4030-10.1371/journal.pone.0004030. · DOI
  23. Nakagawa H, Tamura T, Mitsuda Y, Kurata M, Goto Y, Kamiya Y, Kondo T, Hamajima N: Association between Helicobacter pylori infection detected by the 13C-urea breath test and low serum ferritin levels among Japanese adults. Helicobacter. 2013, 18: 309-315. 10.1111/hel.12044. · DOI
  24. Ganz T, Nemeth E: Hepcidin and iron homeostasis. Biochim Biophys Acta. 1823, 2012: 1434-1443.
  25. Wiltink WF, Kruithof J, Mol C, Bos MG, van Eijk HG: Diurnal and nocturnal variations of the serum iron in normal subjects. Clin Chim Acta. 1973, 49: 99-104. 10.1016/0009-8981(73)90348-3. · DOI
  26. Sinniah R, Doggart JR, Neill DW: Diurnal variations of the serum iron in normal subjects and in patients with haemochromatosis. Br J Haematol. 1969, 17: 351-358. 10.1111/j.1365-2141.1969.tb01381.x. · DOI
  27. Mortensen RF: C-reactive protein, inflammation, and innate immunity. Immunol Res. 2001, 24: 163-176. 10.1385/IR:24:2:163. · DOI

Cited by

Sorted by citations

Metadata

Authors
Nakagawa, H., Tamura, T., Mitsuda, Y., Goto, Y., Kamiya, Y., Kondo, T., Wakai, K., & Hamajima, N.
Venue
BMC Hematology
Publisher
Springer Science and Business Media LLC
Published
2014-02-28
Volume
14
Issue
1
ISSN
2052-1839
DOI
10.1186/2052-1839-14-6
PMC
PMC3974032
Cited by
25
References
6
Language
en
Licence
creativecommons.org/licenses/by/2.0 (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review