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Cited by 346

The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Mammographic density, breast cancer risk and risk prediction

Open access
Vachon, Celine M, van Gils, Carla H, Sellers, Thomas A, Ghosh, Karthik, Pruthi, Sandhya, Brandt, Kathleen R, Pankratz, V Shane·2007·Breast Cancer Research

Abstract

In this review, we examine the evidence for mammographic density as an independent risk factor for breast cancer, describe the risk prediction models that have incorporated density, and discuss the current and future implications of using mammographic density in clinical practice. Mammographic density is a consistent and strong risk factor for breast cancer in several populations and across age at mammogram. Recently, this risk factor has been added to existing breast cancer risk prediction models, increasing the discriminatory accuracy with its inclusion, albeit slightly. With validation, these models may replace the existing Gail model for clinical risk assessment. However, absolute risk estimates resulting from these improved models are still limited in their ability to characterize an individual's probability of developing cancer. Promising new measures of mammographic density, including volumetric density, which can be standardized using full-field digital mammography, will likely result in a stronger risk factor and improve accuracy of risk prediction models.

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Metadata

Authors
Vachon, C. M., van Gils, C. H., Sellers, T. A., Ghosh, K., Pruthi, S., Brandt, K. R., & Pankratz, V. S.
Venue
Breast Cancer Research
Published
2007-12
Volume
9
Issue
6
Pages
217-217
ISSN
  • 1465-5411 (ISSN-L)
  • 1465-542X
OpenAlex
W2151266081
Cited by
346
References
44
FWCI
8.07
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Mammographic density, breast cancer risk and risk prediction. https://app.cochat.ai/papers/10.1186/bcr1829
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Vachon, C. M., van Gils, C. H., Sellers, T. A., Ghosh, K., Pruthi, S., Brandt, K. R., & Pankratz, V. S. (2007). Mammographic density, breast cancer risk and risk prediction. Breast Cancer Research. https://doi.org/10.1186/bcr1829

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.