The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Intracellular signaling pathways of ErbB2/HER-2 and family members
Open accessAbstract
ErbB (also termed HER) receptors are expressed in various tissues of epithelial, mesenchymal and neuronal origin, in which they are involved in the control of diverse biological processes such as proliferation, differentiation, migration and apoptosis. Furthermore, their deregulated expression has been implicated in many types of human cancers and is associated with poor clinical prognosis. Owing to the importance of ErbB proteins in both development and cellular transformation, a lot of attention has been drawn to the intracellular signals initiated by the engagement of this family of receptor tyrosine kinases. This review will focus on the membrane proximal events triggered by the ErbB receptor network and will address questions of how receptor heterodimerization may contribute to signal specification and diversification.
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Cites
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Metadata
- Authors
- Olayioye, M. A.
- Venue
- Breast Cancer Research
- Published
- 2001-12
- Volume
- 3
- Issue
- 6
- Pages
- 385-9
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W1601076886
- Cited by
- 279
- References
- 37
- FWCI
- 0.41
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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