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Cited by 279

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Intracellular signaling pathways of ErbB2/HER-2 and family members

Open access
Olayioye, Monilola A·2001·Breast Cancer Research

Abstract

ErbB (also termed HER) receptors are expressed in various tissues of epithelial, mesenchymal and neuronal origin, in which they are involved in the control of diverse biological processes such as proliferation, differentiation, migration and apoptosis. Furthermore, their deregulated expression has been implicated in many types of human cancers and is associated with poor clinical prognosis. Owing to the importance of ErbB proteins in both development and cellular transformation, a lot of attention has been drawn to the intracellular signals initiated by the engagement of this family of receptor tyrosine kinases. This review will focus on the membrane proximal events triggered by the ErbB receptor network and will address questions of how receptor heterodimerization may contribute to signal specification and diversification.

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Metadata

Authors
Olayioye, M. A.
Venue
Breast Cancer Research
Published
2001-12
Volume
3
Issue
6
Pages
385-9
ISSN
  • 1465-5411 (ISSN-L)
  • 1465-542X
OpenAlex
W1601076886
Cited by
279
References
37
FWCI
0.41
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Intracellular signaling pathways of ErbB2/HER-2 and family members. https://app.cochat.ai/papers/10.1186/bcr327
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Olayioye, M. A. (2001). Intracellular signaling pathways of ErbB2/HER-2 and family members. Breast Cancer Research. https://doi.org/10.1186/bcr327

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.