The DOI matches its Crossref record; 137 of the 141 references it cites were found in a registry or an index.
The origin and early evolution of eukaryotes in the light of phylogenomics
Open accessAbstract
Phylogenomics of eukaryote supergroups suggest a highly complex last common ancestor of eukaryotes and a key role of mitochondrial endosymbiosis in the origin of eukaryotes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Complexity can also occur within cells; a major event in the evolution of eukaryotes was when organisms capable of engulfing other organisms acquired mitochondria (permitting aerobic respiration for energy) and chloroplasts (permitting oxygenic photosynthesis) (Koonin, 2010).”
From The Astrobiology Primer v2.0 (2016) · cites this paper as Koonin, 2010
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Altschul, S. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.17.3389 · Cited by 73,302
Hershko, A., & Ciechanover, A. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.425 · Cited by 8,840
Gray, M. W., Burger, G., & Lang, B. F. (1999) · Science · doi:10.1126/science.283.5407.1476 · Cited by 1,765
The New Higher Level Classification of Eukaryotes with Emphasis on the Taxonomy of Protists
Adl, S., Simpson, A., Farmer, M. A., Andersen, R., Anderson, O., Barta, J. R., Bowser, S., Brugerolle, G., Fensome, R., Fredericq, S., et al. (2005) · Journal of Eukaryotic Microbiology · doi:10.1111/j.1550-7408.2005.00053.x · Cited by 1,749
Phylogenomics and the reconstruction of the tree of life
Delsuc, F., Brinkmann, H., & Philippe, H. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1603 · Cited by 1,264
A kingdom-level phylogeny of eukaryotes based on combined protein data.
Baldauf, S., Roger, A., Wenk-Siefert, I., & Doolittle, W. (2000) · Science · doi:10.1126/science.290.5493.972 · Cited by 1,243
Protein Tyrosine Kinase Structure and Function
Hubbard, S. R., & Till, J. H. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.373 · Cited by 1,176
A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes
Koonin, E. V., Fedorova, N. D., Jackson, J. D., Jacobs, A. R., Krylov, D. M., Makarova, K. S., Mazumder, R., Mekhedov, S., Nikolskaya, A. N., Rao, B. S., et al. (2004) · Genome biology · doi:10.1186/gb-2004-5-2-r7 · Cited by 1,100
Self-citationThe Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
Hunter, T. R. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.11.019 · Cited by 970
Ubiquitin-binding domains — from structures to functions
Đikić, I., Wakatsuki, S., & Walters, K. J. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2767 · Cited by 903
Research works printed but not linked: 1
- Entrez Genome http://www.ncbi.nlm.nih.gov/sites/genome
Cited by
Sorted by citations
Complex archaea that bridge the gap between prokaryotes and eukaryotes
Spang, A., Saw, J. H., Jørgensen, S. L., Zaremba-Niedzwiedzka, K., Martijn, J., Lind, A. E., van Eijk, R., Schleper, C., Guy, L., & Ettema, T. J. G. (2015) · Nature · doi:10.1038/nature14447 · Cited by 1,324
Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes
Müller, M., Mentel, M., van Hellemond, J. J., Henze, K., Woehle, C., Gould, S. B., Yu, R.-Y., van der Giezen, M., Tielens, A. G. M., & Martin, W. F. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05024-11 · Cited by 838
Endosymbiosis and Eukaryotic Cell Evolution
Archibald, J. M. (2015) · Current Biology · doi:10.1016/j.cub.2015.07.055 · Cited by 654
Gray, M. W. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a011403 · Cited by 639
Archaea and the origin of eukaryotes
Eme, L., Spang, A., Lombard, J., Stairs, C. W., & Ettema, T. J. G. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.133 · Cited by 575
Metadata
- Authors
- Koonin, E. V.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Koonin, Eugene V
- ORCID
- Koonin, Eugene V
- Venue
- Genome Biology
- Published
- 2010
- Volume
- 11
- Issue
- 5
- Pages
- 209
- ISSN
- 1465-6906 (ISSN-L)
- PMC
- PMC2898073
- OpenAlex
- W2144889160
- Cited by
- 345
- References
- 141
- Citations by year
- 2026: 10 · 2025: 8 · 2024: 15 · 2023: 7 · 2022: 7 · 2021: 21 · 2020: 13 · 2019: 27 · 2018: 20 · 2017: 26 · 2016: 31 · 2015: 32 · 2014: 35 · 2013: 28 · 2012: 28
- FWCI
- 12.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Genome biology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- U.S. National Library of Medicine
- Topics
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
- Keywords
- eukaryotic origin, eukaryotic evolution, last common ancestor, mitochondrial endosymbiosis, phylogenomics, eukaryotic phylogeny
- MeSH terms
- Archaea, Bacteria, Phylogeny, Genomics, Eukaryota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
