Relative extended haplotype homozygosity signals across breeds reveal dairy and beef specific signatures of selection
Open accessAbstract
BACKGROUND: A number of methods are available to scan a genome for selection signatures by evaluating patterns of diversity within and between breeds. Among these, "extended haplotype homozygosity" (EHH) is a reliable approach to detect genome regions under recent selective pressure. The objective of this study was to use this approach to identify regions that are under recent positive selection and shared by the most representative Italian dairy and beef cattle breeds. RESULTS: A total of 3220 animals from Italian Holstein (2179), Italian Brown (775), Simmental (493), Marchigiana (485) and Piedmontese (379) breeds were genotyped with the Illumina BovineSNP50 BeadChip v.1. After standard quality control procedures, genotypes were phased and core haplotypes were identified. The decay of linkage disequilibrium (LD) for each core haplotype was assessed by measuring the EHH. Since accurate estimates of local recombination rates were not available, relative EHH (rEHH) was calculated for each core haplotype. Genomic regions that carry frequent core haplotypes and with significant rEHH values were considered as candidates for recent positive selection. Candidate regions were aligned across to identify signals shared by dairy or beef cattle breeds. Overall, 82 and 87 common regions were detected among dairy and beef cattle breeds, respectively. Bioinformatic analysis identified 244 and 232 genes in these common genomic regions. Gene annotation and pathway analysis showed that these genes are involved in molecular functions that are biologically related to milk or meat production. CONCLUSIONS: Our results suggest that a multi-breed approach can lead to the identification of genomic signatures in breeds of cattle that are selected for the same production goal and thus to the localisation of genomic regions of interest in dairy and beef production.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Under positive selection, strong and long range linkage disequilibrium and unexpectedly high local haplotype homozygosity might occur in the genome.
“Under positive selection, strong and long range linkage disequilibrium (LD) and unexpectedly high local haplotype homozygosity might occur in the genome (Gautier and Vitalis, 2012; Bomba et al., 2015).”
From Identification of Candidate Signature Genes and Key Regulators Associated With Trypanotolerance in the Sheko Breed (2019) · cites this paper as Bomba et al., 2015
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089 · see citing works
The Neutral Theory of Molecular Evolution
Kimura, M. (1979) · Scientific American · doi:10.1038/scientificamerican1179-98 · Cited by 7,698 · see citing works
The Neutral Theory of Molecular Evolution
Kimura, M. (1983) · Cambridge University Press eBooks · doi:10.1017/cbo9780511623486 · Cited by 6,300 · see citing works
A Map of Recent Positive Selection in the Human Genome
Voight, B. F., Kudaravalli, S., Wen, X., & Pritchard, J. K. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040072 · Cited by 2,912 · see citing works
Detecting recent positive selection in the human genome from haplotype structure
Sabeti, P. C., Reich, D. E., Higgins, J. M., Levine, H. Z. P., Richter, D. J., Schaffner, S. F., Gabriel, S. B., Platko, J. V., Patterson, N. J., McDonald, G. J., et al. (2002) · Nature · doi:10.1038/nature01140 · Cited by 2,106 · see citing works
Scheet, P. A., & Stephens, M. (2006) · The American Journal of Human Genetics · doi:10.1086/502802 · Cited by 1,949 · see citing works
Fructose transporter in human spermatozoa and small intestine is GLUT5.
Burant, C., Takeda, J., Brot‐Laroche, E., Bell, G. I., & Davidson, N. O. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42067-4 · Cited by 545 · see citing works
Recent and ongoing selection in the human genome
Nielsen, R., Hellmann, I., Hubisz, M. J., Bustamante, C. D., & Clark, A. G. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2187 · Cited by 501 · see citing works
ZAP-70: an essential kinase in T-cell signaling
Wang, H., Kadlecek, T. A., Au-Yeung, B. B., Goodfellow, H. E. S., Hsu, L. Y., Freedman, T. S., & Weiss, A. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002279 · Cited by 395 · see citing works
Wickramasinghe, N. S. M. D., Manavalan, T. T., Dougherty, S. M., Riggs, K. A., Li, Y., & Klinge, C. M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp117 · Cited by 391 · see citing works
Correction: A Map of Recent Positive Selection in the Human Genome
Voight, B. F., Kudaravalli, S., Wen, X., & Pritchard, J. K. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040154 · Cited by 386 · see citing works
Neutral theory of molecular evolution
(2015) · The Dictionary of Genomics, Transcriptomics and Proteomics · doi:10.1002/9783527678679.dg08330 · Cited by 385 · see citing works
On the Origin of Cattle: How Aurochs Became Cattle and Colonized the World
Ajmone‐Marsan, P., Garcia, J. F., & Lenstra, J. A. (2010) · Evolutionary Anthropology Issues News and Reviews · doi:10.1002/evan.20267 · Cited by 287 · see citing works
Self-citationClassic Selective Sweeps Revealed by Massive Sequencing in Cattle
Qanbari, S., Pausch, H., Jansen, S., Somel, M., Strom, T. M., Fries, R., Nielsen, R., & Simianer, H. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004148 · Cited by 233 · see citing works
A genome‐wide scan for signatures of recent selection in Holstein cattle
Qanbari, S., Pimentel, E. C. G., Tetens, J., Thaller, G. E., Lichtner, P., Sharifi, A., & Simianer, H. (2010) · Animal Genetics · doi:10.1111/j.1365-2052.2009.02016.x · Cited by 171 · see citing works
Genome-wide signals of positive selection in human evolutionPreprint
Enard, D., Messer, P. W., & Petrov, D. A. (2014) · Genome Research · doi:10.1101/gr.164822.113 · Cited by 167 · see citing works
Qanbari, S., Gianola, D., Hayes, B. J., Schenkel, F. S., Miller, S. P., Moore, S. S., Thaller, G. E., & Simianer, H. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-318 · Cited by 166 · see citing works
Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome
Maningat, P. D., Sen, P., Rijnkels, M., Sunehag, A. L., Hadsell, D. L., Bray, M. S., & Haymond, M. W. (2008) · Physiological Genomics · doi:10.1152/physiolgenomics.90341.2008 · Cited by 159 · see citing works
Molecular tools and analytical approaches for the characterization of farm animal genetic diversity
Lenstra, J. A., Groeneveld, L. F., Eding, H., Kantanen, J., Williams, J. L., Taberlet, P., Nicolazzi, E. L., Sölkner, J., Simianer, H., Ciani, E., et al. (2012) · Animal Genetics · doi:10.1111/j.1365-2052.2011.02309.x · Cited by 157 · see citing works
Self-citationConservation genetics of cattle, sheep, and goats
Taberlet, P., Coissac, É., Pansu, J., & Pompanon, F. (2011) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2010.12.007 · Cited by 151 · see citing works
Programmed cell death in bovine mammary tissue during lactation and involution
Wilde, C., Addey, C., Li, P., & Fernig, D. G. (1997) · Experimental Physiology · doi:10.1113/expphysiol.1997.sp004075 · Cited by 137 · see citing works
Selection for complex traits leaves little or no classic signatures of selection
Kemper, K. E., Saxton, S. J., Bolormaa, S., Hayes, B. J., & Goddard, M. E. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-246 · Cited by 134 · see citing works
Hayes, B. J., Chamberlain, A. J., MacEachern, S., Savin, K. W., McPartlan, H. C., MacLeod, I. M., Sethuraman, L., & Goddard, M. E. (2008) · Animal Genetics · doi:10.1111/j.1365-2052.2008.01815.x · Cited by 125 · see citing works
Narayanan, U. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.15.1785 · Cited by 119 · see citing works
Utsunomiya, Y. T., O’Brien, A. M. P., Sonstegard, T. S., Tassell, C. P. V., do Carmo, A. S., Mészáros, G., Sölkner, J., & Garcia, J. F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064280 · Cited by 108 · see citing works
O’Brien, A. M. P., Utsunomiya, Y. T., Mészáros, G., Bickhart, D. M., Liu, G. E., Tassell, C. P. V., Sonstegard, T. S., Silva, M. V. D., Garcia, J. F., & Sölkner, J. (2014) · Genetics Selection Evolution · doi:10.1186/1297-9686-46-19 · Cited by 97 · see citing works
Developmental and Epigenetic Anomalies in Cloned Cattle
Smith, L. C., Suzuki, J., GOFF, A. K., Filion, F., Therrien, J., Murphy, B. D., Kohan‐Ghadr, H., Lefebvre, R. C., Brisville, A.-C., Buczinski, S., et al. (2012) · Reproduction in Domestic Animals · doi:10.1111/j.1439-0531.2012.02063.x · Cited by 96 · see citing works
The origin of selection signatures on bovine chromosome 6
Hayes, B. J., Lien, S., Nilsen, H., Olsen, H. G., Berg, P. R., MacEachern, S., Potter, S., & Meuwissen, T. H. E. (2008) · Animal Genetics · doi:10.1111/j.1365-2052.2007.01683.x · Cited by 90 · see citing works
Kuhla, B., Nürnberg, G., Albrecht, D., Görs, S., Hammon, H. M., & Metges, C. C. (2011) · Journal of Proteome Research · doi:10.1021/pr200425h · Cited by 88 · see citing works
Bonnefont, C. M. D., Toufeer, M., Caubet, C., Foulon, E., Tasca, C., Aurel, M.-R., Bergonier, D., Boullier, S., Robert-Granié, C., Foucras, G., et al. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-208 · Cited by 85 · see citing works
Autocrine-Paracrine Endothelin System in the Physiology and Pathology of Steroid-Secreting Tissues
Nussdorfer, G. G., Rossi, G. P., Malendowicz, L. K., & Mazzocchi, G. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01413-3 · Cited by 80 · see citing works
Nishimura, T., Hattori, A., & Takahashi, K. (1996) · Meat Science · doi:10.1016/0309-1740(95)00051-8 · Cited by 77 · see citing works
Acosta, T. J., Berisha, B., Ozawa, T., Kunitada, S. A. T. O., Schams, D., & Miyamoto, A. (1999) · Biology of Reproduction · doi:10.1095/biolreprod61.6.1419 · Cited by 75 · see citing works
Zhang, C., Bailey, D. K., Awad, T. A., Liu, G., Xing, G., Cao, M., Valmeekam, V., Retief, J., Matsuzaki, H., Taub, M. A., et al. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl365 · Cited by 71 · see citing works
Iqbal, S., Zebeli, Q., Mazzolari, A., Bertoni, G., Dunn, S. M., Yang, W. Z., & Ametaj, B. N. (2009) · Journal of Dairy Science · doi:10.3168/jds.2009-2380 · Cited by 67 · see citing works
Yasuda, S., Stevens, R. L., Terada, T., Takeda, M., Hashimoto, T., Fukae, J., Horita, T., Kataoka, H., Atsumi, T., & Koike, T. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.7.4890 · Cited by 65 · see citing works
Dubost, A., Micol, D. D., Picard, B. B., Lethias, C., Andueza, D., Bauchart, D., & Listrat, A. (2013) · Meat Science · doi:10.1016/j.meatsci.2013.05.040 · Cited by 65 · see citing works
Glucose transporter gene expression in lactating bovine gastrointestinal tract.
Zhao, F., Okine, E. K., Cheeseman, C. I., Shirazi‐Beechey, S. P., & Kennelly, J. J. (1998) · Journal of Animal Science · doi:10.2527/1998.76112921x · Cited by 60 · see citing works
Application of Top-Down and Bottom-up Systems Approaches in Ruminant Physiology and Metabolism
Shahzad, K., & Loor, J. J. (2012) · Current Genomics · doi:10.2174/138920212801619269 · Cited by 52 · see citing works
Madani, S., Hichami, A., Cherkaoui‐Malki, M., & Khan, N. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306252200 · Cited by 49 · see citing works
Estradiol downregulates miR-21 expression and miR-21 gene targets in MCF-7 breast cancer cells.
Wickramasinghe, N. S. M. D., Manavalan, T. T., Riggs, K., Li, Y., & Klinge, C. M. (2009) · Cancer Research · doi:10.1158/0008-5472.sabcs-3051 · Cited by 45 · see citing works
Ezura, Y., Kajita, M., Ishida, R., Yoshida, S., Yoshida, H., Suzuki, T., Hosoi, T., Inoue, S., Shiraki, M., Orimo, H., et al. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.040324 · Cited by 44 · see citing works
Dupont‐Versteegden, E. E., Nagarajan, R., Beggs, M. L., Bearden, E. D., Simpson, P. M., & Peterson, C. A. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90455.2008 · Cited by 40 · see citing works
Sun, G., Cheng, S. Y. S., Chen, M., Lim, C. J., & Pallen, C. J. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00214-12 · Cited by 35 · see citing works
Signatures of selection in five Italian cattle breeds detected by a 54K SNP panel
Mancini, G., Gargani, M., Chillemi, G., Nicolazzi, E. L., Ajmone‐Marsan, P., Valentini, A., & Pariset, L. (2014) · Molecular Biology Reports · doi:10.1007/s11033-013-2940-5 · Cited by 32 · see citing works
Self-citationGenome-Wide Detection of Selective Signature in Chinese Holstein
Pan, D., Zhang, S., Jiang, J., Jiang, L., Zhang, Q., & Liu, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060440 · Cited by 30 · see citing works
Genome-wide detection of selective signatures in Simmental cattle
Fan, H., Wu, Y., Qi, X., Zhang, J., Li, J., Gao, X., Zhang, L., Li, J., & Gao, H. (2014) · Journal of Applied Genetics · doi:10.1007/s13353-014-0200-6 · Cited by 29 · see citing works
Puglisi, R., Cambuli, C., Capoferri, R., Giannino, L., Lukaj, A., Duchi, R., Lazzari, G., Galli, C., Feligini, M., Galli, A., et al. (2013) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2013.07.003 · Cited by 20 · see citing works
Rb1cc1 is critical for myoblast differentiation through Rb1 regulation
Watanabe, R., Chano, T., Inoue, H., Isono, T., Koiwai, O., & Okabe, H. (2005) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-004-1183-1 · Cited by 14 · see citing works
Wang, M., Zhang, X., Kang, L., Jiang, C., & Jiang, Y. (2012) · Molecular Biology Reports · doi:10.1007/s11033-012-1806-6 · Cited by 11 · see citing works
Ephrin-A5 promotes bovine muscle progenitor cell migration before mitotic activation1
Li, J., & Johnson, S. (2013) · Journal of Animal Science · doi:10.2527/jas.2012-5728 · Cited by 10 · see citing works
Exploring polymorphisms and associations of the bovine MOGAT3 gene with growth traits
Sun, J., Zhang, C., Lan, X., Lei, C., & Chen, H. (2012) · Genome · doi:10.1139/g11-077 · Cited by 8 · see citing works
Detecting selection signatures on X chromosome in pig through high density SNPs
Ma, Y., Zhang, Q., & Ding, X. (2012) · Hereditas (Beijing) · doi:10.3724/sp.j.1005.2012.01251 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Selection signatures in livestock genome: A review of concepts, approaches and applications
Saravanan, K. A., Panigrahi, M., Kumar, H., Bhushan, B., Dutt, T., & Mishra, B. P. (2020) · Livestock Science · doi:10.1016/j.livsci.2020.104257 · Cited by 150 · see citing works
A Meta-Assembly of Selection Signatures in Cattle
Randhawa, I. A. S., Khatkar, M. S., Thomson, P. C., & Raadsma, H. W. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153013 · Cited by 101 · see citing works
Palombo, V., Milanesi, M., Sgorlon, S., Capomaccio, S., Mele, M. L., Nicolazzi, E. L., Ajmone‐Marsan, P., Pilla, F., Stefanon, B., & D’Andrea, M. (2018) · Journal of Dairy Science · doi:10.3168/jds.2018-14413 · Cited by 90 · see citing works
Self-citationIso‐Touru, T., Tapio, M., Vilkki, J., Kiseleva, T., Ammosov, I., Ivanova, Z., Popov, R. G., Ozerov, M. Y., & Kantanen, J. (2016) · Animal Genetics · doi:10.1111/age.12473 · Cited by 91 · see citing works
Population structure and genomic inbreeding in nine Swiss dairy cattle populations
Signer‐Hasler, H., Burren, A., Neuditschko, M., Frischknecht, M., Garrick, D. J., Stricker, C., Gredler, B., Bapst, B., & Flury, C. (2017) · Genetics Selection Evolution · doi:10.1186/s12711-017-0358-6 · Cited by 78 · see citing works
Adaptive introgression from indicine cattle into white cattle breeds from Central Italy
Barbato, M., Hailer, F., Upadhyay, M. R., Corvo, M. D., Colli, L., Negrini, R., Kim, E.-S., Crooijmans, R. P. M. A., Sonstegard, T. S., & Ajmone‐Marsan, P. (2020) · Scientific Reports · doi:10.1038/s41598-020-57880-4 · Cited by 77 · see citing works
Self-citationSignatures of selection in the genome of Swedish warmblood horses selected for sport performance
Ablondi, M., Viklund, Å., Lindgren, G., Eriksson, S., & Mikko, S. (2019) · BMC Genomics · doi:10.1186/s12864-019-6079-1 · Cited by 77 · see citing works
Mezzetti, M., Cattaneo, L., Passamonti, M. M., Lopreiato, V., Minuti, A., & Trevisi, E. (2021) · Dairy · doi:10.3390/dairy2040048 · Cited by 75 · see citing works
Guo, J., Zhong, J., Li, L., Zhong, T., Wang, L., Song, T., & Zhang, H. (2019) · Genetics Selection Evolution · doi:10.1186/s12711-019-0512-4 · Cited by 70 · see citing works
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G.-L., Shen, X., Zhao, X., Wang, Q., et al. (2021) · BMC Genomics · doi:10.1186/s12864-021-08042-x · Cited by 64 · see citing works
Worku, D., Hussen, J., De Matteis, G., Schusser, B., & Alhussien, M. N. (2023) · Frontiers in Veterinary Science · doi:10.3389/fvets.2023.1151241 · Cited by 43 · see citing works
Mekonnen, Y. A., Gültas, M., Effa, K., Hanotte, O., & Schmitt, A. O. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.01095 · Cited by 37 · see citing works
Barrera‐Redondo, J., Piñero, D., & Eguiarte, L. E. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00742 · Cited by 35 · see citing works
Jemaa, S. B., Senczuk, G., Ciani, E., Ciampolini, R., Catillo, G., Boussaha, M., Pilla, F., Portolano, B., & Mastrangelo, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.675569 · Cited by 36 · see citing works
González‐Rodríguez, A., Munilla, S., Mouresan, E. F., Álvarez, J. J. C., Díaz, C., Piedrafita, J., Altarriba, J., de la Fuente, J. Á. B., Molina, A., & Varona, L. (2016) · Genetics Selection Evolution · doi:10.1186/s12711-016-0258-1 · Cited by 32 · see citing works
Identification of genome‐wide selection signatures in the L imousin beef cattle breed
Gurgul, A., Szmatoła, T., Ropka‐Molik, K., Jasielczuk, I., Pawlina‐Tyszko, K., Semik, E., & Bugno‐Poniewierska, M. (2015) · Journal of Animal Breeding and Genetics · doi:10.1111/jbg.12196 · Cited by 31 · see citing works
de Greef, E., Einfeldt, A. L., Miller, P. J. O., Ferguson, S. H., Garroway, C. J., Lefort, K. J., Paterson, I. G., Bentzen, P., & Feyrer, L. (2022) · Molecular Ecology · doi:10.1111/mec.16643 · Cited by 23 · see citing works
Selection signatures for high altitude adaptation in livestock: A review
Tiwari, M., Gujar, G., Shashank, C. G., & Ponsuksili, S. (2024) · Gene · doi:10.1016/j.gene.2024.148757 · Cited by 27 · see citing works
Genomic Divergence in Swedish Warmblood Horses Selected for Equestrian Disciplines
Ablondi, M., Eriksson, S., Tetu, S., Sabbioni, A., Viklund, Å., & Mikko, S. (2019) · Genes · doi:10.3390/genes10120976 · Cited by 26 · see citing works
Genome-wide detection of selective signatures in a Duroc pig population
Diao, S., Luo, Y., Ma, Y., Xi, D. E. N. G., He, Y., Gao, N., Zhang, H., Li, J., Chen, Z., & Zhang, Z. (2018) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(18)61984-7 · Cited by 22 · see citing works
Campos, B. M., do Carmo, A. S., da Silva, T. B. R., Verardo, L. L., Gouveia, J. J. D. S., Malhado, C. H. M., da Silva, M. V. G. B., & Carneiro, P. L. S. (2017) · Livestock Science · doi:10.1016/j.livsci.2017.10.014 · Cited by 22 · see citing works
Vanvanhossou, S. F. U., Yin, T., Scheper, C., Fries, R., Dossa, L. H., & König, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.657282 · Cited by 19 · see citing works
The Bos taurus–Bos indicus balance in fertility and milk related genes
Kasarapu, P., Neto, L. R. P., Fortes, M. R. S., Lehnert, S. A., Mudadu, M. A., Coutinho, L. L., Regitano, L. C. D. A., George, A. W., & Reverter, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181930 · Cited by 16 · see citing works
Genome-wide detection of selective signatures in a Jinhua pig population
Xu, Z., Sun, H., Zhang, Z., Qing-bo, Z. H. A. O., Olasege, B. S., Li, Q., Yang, Y., Ma, P., Zhang, X., Qi-shan, W. A. N. G., et al. (2020) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(19)62833-9 · Cited by 15 · see citing works
Genetic Regulation of Biomarkers as Stress Proxies in Dairy Cows
Milanesi, M., Passamonti, M. M., Cappelli, K., Minuti, A., Palombo, V., Sgorlon, S., Capomaccio, S., D’Andrea, M., Trevisi, E., Stefanon, B., et al. (2021) · Genes · doi:10.3390/genes12040534 · Cited by 14 · see citing works
Self-citationSignatures of selection in Charolais beef cattle identified by genome‐wide analysis
Jahuey‐Martínez, F. J., Parra‐Bracamonte, G. M., Sifuentes‐Rincón, A. M., & Moreno-Medina, V. R. (2019) · Journal of Animal Breeding and Genetics · doi:10.1111/jbg.12399 · Cited by 14 · see citing works
Orbán, L., Shen, X., Phua, N., & Varga, L. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.506754 · Cited by 14 · see citing works
Kumar, S., V, Deng, C. H., Hunt, M., Kirk, C. M., Wiedow, C., Rowan, D. D., Wu, J., & Brewer, L. R. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2020.590846 · Cited by 12 · see citing works
Ablondi, M., Malacarne, M., Cipolat‐Gotet, C., van Kaam, J.-T., Sabbioni, A., & Summer, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-92168-1 · Cited by 11 · see citing works
Selection signatures in candidate genes and QTL for reproductive traits in Nellore heifers
Montes-Vergara, D. E., Braz, C. U., Ribeiro, A. M. F., Cavani, L., Barbero, M. M. D., de Albuquerque, L. G., Curi, R. A., & de Oliveira, H. N. (2019) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2019.06.004 · Cited by 9 · see citing works
A practical approach to detect ancestral haplotypes in livestock populations
Sánchez-Molano, E., Tsiokos, D., Chatziplis, D., Jorjani, H., Degano, L., Díaz, C., Rossoni, A., Schwarzenbacher, H., Seefried, F. R., Varona, L., et al. (2016) · BMC Genetics · doi:10.1186/s12863-016-0405-2 · Cited by 3 · see citing works
Self-citationPublic policymaking and its analysis at National and European Levels
Majone, G. (2015) · Studia z Polityki Publicznej · doi:10.33119/kszpp.2015.2.1 · Cited by 2 · see citing works
Metabolism and Inflammation in Dairy Cows
Mezzetti, M., Carpenter, G., Bradford, B. J., & Trevisi, E. (2024) · Springer eBooks · doi:10.1007/978-3-031-51788-4_4 · Cited by 2 · see citing works
Vibration Analysis of Motor Yacht
Pais, T. (2017) · International Journal of Oceanography & Aquaculture · doi:10.23880/ijoac-16000120 · Cited by 1 · see citing works
Perera, D., Reisenhofer, E., Hussein, S., Higgins, E., Huber, C. D., & Long, Q. (2023) · Methods in Ecology and Evolution · doi:10.1111/2041-210x.14168 · Cited by 1 · see citing works
Kim, J., Kim, J., Cho, E., Cho, S., Kim, M., Chung, W.-H., Choi, J.-W., Choo, H.-J., & Lee, J. H. (2025) · Animal Bioscience · doi:10.5713/ab.24.0718 · Cited by 1 · see citing works
Lukaszewicz, M., Salia, O. I., Hohenlohe, P. A., & Buzbas, E. O. (2024) · Journal of Computational Mathematics and Data Science · doi:10.1016/j.jcmds.2024.100091
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G.-L., Shen, X., Zhao, X., Wang, Q., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16821682
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G.-L., Shen, X., Zhao, X., Wang, Q., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16821685
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G.-L., Shen, X., Zhao, X., Wang, Q., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16821688
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G.-L., Shen, X., Zhao, X., Wang, Q., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16821679
Çiftlik Hayvanlarında Seleksiyon İzlerinin Tanımlanmasında Kullanılan Kavram ve Yaklaşımlar
Karabaş, M., & Yılmaz, O. (2024) · Hayvan Bilimi ve Ürünleri Dergisi · doi:10.51970/jasp.1390270
Liu, D., Chen, Z., Zhao, W., Guo, L., Sun, H., Zhu, K., Liu, G., Shen, X., Zhao, X., Wang, Q., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16821676
Miksza-Cybulska, A., Kawęcka, A., & Gurgul, A. (2026) · Annals of Animal Science · doi:10.2478/aoas-2026-0009
- Authors
- Bomba, L., Nicolazzi, E. L., Milanesi, M., Negrini, R., Mancini, G., Biscarini, F., Stella, A., Valentini, A., & Ajmone-Marsan, P.
- Affiliations
- Università Cattolica del Sacro Cuore (IT)
- Parco Tecnologico Padano (IT)
- Scuola Normale Superiore (IT)
- Università degli Studi della Tuscia (IT)
- Corresponding author
- Bomba, Lorenzo
- ORCID
- Venue
- Genetics Selection Evolution
- Published
- 2015-04-02
- Volume
- 47
- Issue
- 1
- Pages
- 25-25
- ISSN
- 0999-193X (ISSN-L)
- 1297-9686
- PMC
- PMC4383072
- OpenAlex
- W2126575387
- Cited by
- 42
- References
- 53
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 1 · 2021: 9 · 2020: 4 · 2019: 6 · 2018: 3 · 2017: 4 · 2016: 4 · 2015: 2
- FWCI
- 2.98
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Genetics Selection Evolution (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- UnitusOpen (Tuscia University) (submittedVersion)
- PubliCatt (Università Cattolica del Sacro Cuore) (submittedVersion, cc-by)
- Scuola Normale Superiore di Pisa (submittedVersion, cc-by)
- Funders
- Fondazione Cariplo
- Ministero delle Politiche Agricole Alimentari e Forestali
- Fondazione Banca Popolare di Lodi
- Regione Lombardia
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- extended haplotype homozygosity, positive selection signatures, dairy cattle, beef cattle, Italian cattle breeds, Holstein, Brown Swiss cattle, Simmental cattle, Marchigiana, Piedmontese, linkage disequilibrium, recombination rate
- MeSH terms
- Animals, Breeding, Cattle, Dairying, Haplotypes, Homozygote, Male, Meat, Selection, Genetic, Genomics, Molecular Sequence Annotation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
