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Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves

Open access
Sprouffske, Kathleen, Wagner, Andreas·2016·BMC Bioinformatics

Abstract

Background: Plate readers can measure the growth curves of many microbial strains in a high-throughput fashion. The hundreds of absorbance readings collected simultaneously for hundreds of samples create technical hurdles for data analysis. Results: Growthcurver summarizes the growth characteristics of microbial growth curve experiments conducted in a plate reader. The data are fitted to a standard form of the logistic equation, and the parameters have clear interpretations on population-level characteristics, like doubling time, carrying capacity, and growth rate. Conclusions: Growthcurver is an easy-to-use R package available for installation from the Comprehensive R Archive Network (CRAN). The source code is available under the GNU General Public License and can be obtained from Github (Sprouffske K, Growthcurver sourcecode, 2016).

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Metadata

Authors
Sprouffske, K., & Wagner, A.
Venue
BMC Bioinformatics
Published
2016-04-19
Volume
17
Issue
1
Pages
172-172
ISSN
1471-2105 (ISSN-L)
OpenAlex
W2338194256
Cited by
847
References
19
FWCI
21.85
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves. https://app.cochat.ai/papers/10.1186/s12859-016-1016-7
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Sprouffske, K., & Wagner, A. (2016). Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves. BMC Bioinformatics. https://doi.org/10.1186/s12859-016-1016-7

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