Cited by 49

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Strong association between metabolically-abnormal obesity and gallstone disease in adults under 50 years

Su, Pei-yuan, Hsu, Yu-Chun, Cheng, Yu-fang, Kor, Chew-Teng, Su, Wei-Wen·2019·BMC Gastroenterology

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Crossref · 10.1186/s12876-019-1032-y

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  • The prevalence of gallstones in individuals younger than 50 years with obesity and metabolic syndrome was identical to the prevalence in elderly people who were metabolically healthy and not obese.

    “the prevalence of gallstones in individuals younger than 50 years with obesity and metabolic syndrome was identical to the prevalence of gallstones in elderly people who were metabolically healthy and not obese.”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [15]

    The Conclusions describe the two groups’ gallstone prevalence as equal, supporting the comparison. The Results (Baseline characteristics) give rates of 7.2% and 6.8%, however, so the prevalences were similar rather than numerically identical. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • The influence of body weight on gallstones has been suggested to occur independently of age.

    “The influence of body weight on gallstones has also recently been suggested to occur independently of age.”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [15]

    The Results (Baseline characteristics; page unavailable) report higher gallstone rates in certain obesity/metabolic phenotypes in both age groups, and the Discussion reports an association after adjustment for age. But the Results also find a significant interaction by age: the obesity/metabolic phenotypes were significant risk factors only below age 50. The paper therefore supports an association beyond age alone, not an influence that is the same regardless of age. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • In a retrospective cross-sectional Asian study, participants younger than 50 years had a higher risk of gallstones (OR = 5.4; 95% CI 2.3-12.7) if they were obese and had features of metabolic syndrome.

    “a retrospective cross-sectional Asian study [15] observed participants younger than 50 years to have a higher risk of gallstones (OR = 5.4; 95% CI 2.3-12.7)if they were obese and showed features of the metabolic syndrome.”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [15]

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Citations

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Research works printed but not linked: 34

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  3. Lin I-C, Yang Y-W, Wu M-F, et al. The association of metabolic syndrome and its factors with gallstone disease. BMC Fam Pract. 2014;15:138. · DOI
  4. Li X, Guo X, Ji H, Yu G, Gao P. Gallstones in Patients with Chronic Liver Diseases. Biomed Res Int. 2017;2017:9749802.
  5. Lammert F, Gurusamy K, Ko CW, et al. Gallstones. Nat Rev Dis Prim. 2016;2:16024. · DOI · Paper page
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  7. Ahmed F, Baloch Q, Memon ZA, Ali I. An observational study on the association of nonalcoholic fatty liver disease and metabolic syndrome with gall stone disease requiring cholecystectomy. Ann Med Surg. 2017;17:7–13. · DOI
  8. Zhu Q, Sun X, Ji X, et al. The association between gallstones and metabolic syndrome in urban Han Chinese: a longitudinal cohort study. Sci Rep. 2016;6:1–9. · DOI · Paper page
  9. Tsai CH, Wu JS, Chang YF, Lu FH, Yang YC, Chang CJ. The number of metabolic abnormalities associated with the risk of gallstones in a non-diabetic population. PLoS One. 2014;9:1–6.
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Metadata

Authors
Su, P.-Y., Hsu, Y.-C., Cheng, Y.-F., Kor, C.-T., & Su, W.-W.
Venue
BMC Gastroenterology
Published
2019-07-04
Volume
19
Issue
1
ISSN
1471-230X
Cited by
49
References
1
Language
en

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