Associations of sociodemographic and clinical factors with perinatal depression among Israeli women: a cross-sectional study
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Background: Perinatal depression is a common problem that affects about 18% of women worldwide, though the heterogeneity between countries is great. The aims of this study were to assess the prevalence of perinatal depressive symptoms in a national sample of women in Israel, and to investigate associations of these symptoms with demographic, medical and lifestyle factors. Methods: The study included all members of Maccabi Health Services, the second largest health maintenance organization in Israel, who filled the Edinburgh Postnatal Depression Scale (EPDS) during 2015–2016. Crude odds ratios (ORs) and adjusted ORs (aORs) are presented for associations of sociodemographic, medical and lifestyle factors with perinatal depressive symptoms, according to a score ≥ 10 on the EPDS. Results: Of 27,520 women who filled the EPDS, 1346 (4.9%) met the criteria for perinatal depression. In a logistic regression analysis we found the following factors associated with perinatal depression: the use of antidepressant medications (aOR = 2.34, 95% CI 1.94–2.82, P < 0.001 and aOR = 3.44; 95% CI 2.99–3.97, P < 0.001 for ≤3 months and > 3 months respectively), a diagnosis of chronic diabetes mellitus (aOR = 2.04; 95% CI 1.22–3.43, P = 0.007), Arab background (aOR = 2.28; 95% CI 1.82–2.86, P < 0.001), current and past smoking (aOR = 1.62; 95% CI 1.35–1.94, P < 0.001 and aOR = 1.36; 95% CI 1.05–1.76, P = 0.021, respectively), and anaemia (aOR = 1.17; 95% CI 1.04–1.32, P = 0.011). Orthodox Jewish affiliation and residence in the periphery of the country were associated with lower perinatal depression (aOR = 0.48; 95% CI 0.36–0.63, P < 0.001 and aOR = 0.72; 95% CI 0.57–0.92, P = 0.007, respectively). Conclusions: The prevalence of perinatal depression in this study was 4.9%. Perinatal depression was associated with a number of demographic, medical and lifestyle factors, including the use of antidepressant medication, chronic diabetes mellitus, Arab background, current or past smoking, and anaemia. These risk factors may help identify women at risk of perinatal depression.
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The prevalence of postpartum depression in Israel is estimated around 5-20%, depending on ethnic background.
“The prevalence in Israel is estimated around 5–20%, depending on ethnic background [2, 3].”
From Challenges in diagnosing and treating postpartum depression in the primary care Setting- a qualitative study (2025) · cites this paper as [2]
The Background (page unavailable) reports that Israeli studies found perinatal depression rates of 5.2–43.0%, not an estimated postpartum prevalence of 5–20%. The Discussion (page unavailable) reports differences by population group, with greater risk among Arab women and lower risk among Orthodox Jewish women, but does not establish the claimed range by ethnic background. (LLM, conf=0.87)
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Krepak, D. K., Kopit, A. B., Biderman, A., Yehoshua, I., & Adler, L. (2025) · BMC Primary Care · doi:10.1186/s12875-025-03004-8 · Cited by 1 · see citing works
Self-citation
- Authors
- Adler, L., Tsamir, J., Katz, R., Koren, G., & Yehoshua, I.
- Affiliations
- Tel Aviv University (IL)
- Maccabi Healthcare Services (IL)
- Ariel University (IL)
- Ben-Gurion University of the Negev (IL)
- Corresponding author
- Adler, Limor
- Venue
- BMC Psychiatry
- Published
- 2019-11-01
- Volume
- 19
- Issue
- 1
- Pages
- 331-331
- ISSN
- 1471-244X (ISSN-L)
- PMC
- PMC6824132
- OpenAlex
- W2983472602
- Cited by
- 13
- References
- 6
- Citations by year
- 2026: 2 · 2025: 3 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 1
- FWCI
- 1.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Psychiatry (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Kahn-Sagol-Maccabi Research and Innovation Institute
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- perinatal depression, postpartum depression, sociodemographic factors, clinical risk factors, antidepressant use, chronic diabetes mellitus, Arab women, smoking during pregnancy, anemia, rural residence, prevalence, Edinburgh Postnatal Depression Scale, Israel, health maintenance organization members, lifestyle factors, ethnic differences in mental health
- MeSH terms
- Adult, Cross-Sectional Studies, Depression, Female, Humans, Israel, Pregnancy, Pregnancy Complications, Psychiatric Status Rating Scales, Risk Factors, Prevalence, Odds Ratio, Arabs, Young Adult
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