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The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data
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“Evidence from recent systematic reviews and meta-analyses consistently indicates that peppermint oil is the most effective botanical agent, particularly for reducing abdominal pain and overall IBS symptom severity.”
From Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines (2026) · cites this paper as [34]
In the citing paper
“The efficacy of peppermint oil in IBS is also corroborated by two recent systematic reviews and meta-analyses of eligible trials, which found that this plant extract was safe and superior to placebo in reducing abdominal pain and global IBS symptoms.”
From Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines (2026) · cites this paper as [34]
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The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
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GRADE guidelines: 3. Rating the quality of evidence
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Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Lovell, R. M., & Ford, A. C. (2012) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2012.02.029 · Cited by 2,155
Schmulson, M. J., & Drossman, D. A. (2017) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16214 · Cited by 788
Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome
Ruepert, L., Quartero, A. O., de Wit, N. J., van der Heijden, G. J., Rubin, G., & Muris, J. W. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003460.pub3 · Cited by 389
American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome
Ford, A. C., Moayyedi, P., Chey, W. D., Harris, L. A., Lacy, B. E., Saito, Y. A., & Quigley, E. M. M. (2018) · American Journal of Gastroenterology · doi:10.1038/s41395-018-0084-x · Cited by 388 · cited 6×
“In 2018 Ford et al. published a systematic review of RCTs using medical, psychological and nutritional therapies for IBS as an updated monograph for the American College of Gastroenterology [44].”
BackgroundInfluentialThe Role of Diet in the Treatment of Irritable Bowel Syndrome
Singh, R., Salem, A., Nanavati, J., & Mullin, G. E. (2018) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2017.10.003 · Cited by 42
Self-citation
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Cited by
ACG Clinical Guideline: Management of Irritable Bowel Syndrome
Lacy, B. E., Pimentel, M., Brenner, D. M., Chey, W. D., Keefer, L. A., Long, M. D., & Moshiree, B. (2021) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001036 · Cited by 893
Weerts, Z. Z. R. M., Masclee, A. A. M., Witteman, B. J. M., Clemens, C. H. M., Winkens, B., Brouwers, J. R. B. J., Frijlink, H. W., Muris, J. W. M., De Wit, N. J., Essers, B. A. B., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2019.08.026 · Cited by 137
Pastras, P., Aggeletopoulou, I., Bali, M., & Triantos, C. (2026) · Nutrients · doi:10.3390/nu18020183 · Cited by 1
Metadata
- Authors
- Alammar, N., Wang, L., Saberi, B., Nanavati, J., Holtmann, G., Shinohara, R. T., & Mullin, G. E.
- Venue
- BMC Complementary and Alternative Medicine
- Published
- 2019-01-17
- Volume
- 19
- Issue
- 1
- ISSN
- 1472-6882
- Cited by
- 132
- References
- 9
- Language
- en
- Licence
- creativecommons.org/licenses/by/4.0/ (tdm)
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- Alammar, N., Wang, L., Saberi, B., Nanavati, J., Holtmann, G., Shinohara, R. T., & Mullin, G. E. (2019). The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complementary and Alternative Medicine. https://doi.org/10.1186/s12906-018-2409-0
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