Beyond the hype of big data and artificial intelligence: building foundations for knowledge and wisdom
Open accessAbstract
Big data, coupled with the use of advanced analytical approaches, such as artificial intelligence (AI), have the potential to improve medical outcomes and population health. Data that are routinely generated from, for example, electronic medical records and smart devices have become progressively easier and cheaper to collect, process, and analyze. In recent decades, this has prompted a substantial increase in biomedical research efforts outside traditional clinical trial settings. Despite the apparent enthusiasm of researchers, funders, and the media, evidence is scarce for successful implementation of products, algorithms, and services arising that make a real difference to clinical care. This article collection provides concrete examples of how "big data" can be used to advance healthcare and discusses some of the limitations and challenges encountered with this type of research. It primarily focuses on real-world data, such as electronic medical records and genomic medicine, considers new developments in AI and digital health, and discusses ethical considerations and issues related to data sharing. Overall, we remain positive that big data studies and associated new technologies will continue to guide novel, exciting research that will ultimately improve healthcare and medicine-but we are also realistic that concerns remain about privacy, equity, security, and benefit to all.
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The shifting roles and responsibilities identified in the study reflect a broader trend in healthcare where technology necessitates new skill sets and professional roles.
“The shifting roles and responsibilities identified in the study reflect a broader trend in healthcare where technology necessitates new skill sets and professional roles [27].”
From Leading with AI in critical care nursing: challenges, opportunities, and the human factor (2024) · cites this paper as [27]
Anonymizing data whenever feasible adds an extra layer of privacy, allowing educational insights without compromising individuals' identities.
“Anonymizing data whenever feasible adds an extra layer of privacy, allowing educational insights without compromising individuals’ identities [22].”
From Twelve tips for addressing ethical concerns in the implementation of artificial intelligence in medical education (2024) · cites this paper as [22]
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Roth, G. A., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdela, J., Abdelalim, A., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32203-7 · Cited by 8,600 · see citing works
Kyu, H. H., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdela, J., Abdelalim, A., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32335-3 · Cited by 4,111 · see citing works
RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review
Glasgow, R. E., Harden, S. M., Gaglio, B., Rabin, B., Smith, M. L., Porter, G. C., Ory, M. G., & Estabrooks, P. A. (2019) · Frontiers in Public Health · doi:10.3389/fpubh.2019.00064 · Cited by 2,528 · see citing works
Welcome to Implementation Science
Eccles, M. P., & Mittman, B. S. (2006) · Implementation Science · doi:10.1186/1748-5908-1-1 · Cited by 2,254 · see citing works
The Inevitable Application of Big Data to Health Care
Murdoch, T. B., & Detsky, A. S. (2013) · JAMA · doi:10.1001/jama.2013.393 · Cited by 1,676 · see citing works
Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2
Hippisley-Cox, J., Coupland, C., Vinogradova, Y., Robson, J., Minhas, R., Sheikh, A., & Brindle, P. (2008) · BMJ · doi:10.1136/bmj.39609.449676.25 · Cited by 1,459 · see citing works
Self-citationData Sharing by Scientists: Practices and Perceptions
Tenopir, C., Allard, S., Douglass, K., Aydinoglu, A. U., Wu, L., Read, E., Manoff, M., & Frame, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021101 · Cited by 1,432 · see citing works
Practice-based research--“Blue Highways” on the NIH roadmap
Westfall, J. M., Mold, J., & Fagnan, L. (2007) · JAMA · doi:10.1001/jama.297.4.403 · Cited by 1,209 · see citing works
Predictive, personalized, preventive, participatory (P4) cancer medicine
Hood, L., & Friend, S. H. (2011) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2010.227 · Cited by 925 · see citing works
Charting a course for genomic medicine from base pairs to bedside
Green, E. D., & Guyer, M. S. (2011) · Nature · doi:10.1038/nature09764 · Cited by 901 · see citing works
Khoury, M. J., GWINN, M. L., Yoon, P. W., Dowling, N. F., Moore, C. A., & Bradley, L. (2007) · Genetics in Medicine · doi:10.1097/gim.0b013e31815699d0 · Cited by 708 · see citing works
Medical big data: promise and challenges
Lee, C. H., & Yoon, H. (2017) · Kidney Research and Clinical Practice · doi:10.23876/j.krcp.2017.36.1.3 · Cited by 596 · see citing works
Newton, K. M., Peissig, P. L., Kho, A. N., Bielinski, S. J., Berg, R. L., Choudhary, V., Basford, M., Chute, C. G., Kullo, I. J., Li, R., et al. (2013) · Journal of the American Medical Informatics Association · doi:10.1136/amiajnl-2012-000896 · Cited by 414 · see citing works
Birken, S. A., Powell, B. J., Presseau, J., Kirk, M. A., Lorencatto, F., Gould, N. J., Shea, C. M., Weiner, B. J., Francis, J., Yu, Y., et al. (2017) · Implementation Science · doi:10.1186/s13012-016-0534-z · Cited by 387 · see citing works
Management support systems: Towards integrated knowledge management
Zelený, M. (1987) · Human Systems Management · doi:10.3233/hsm-1987-7108 · Cited by 337 · see citing works
Mackey, T. K., Kuo, T.-T., Gummadi, B., Clauson, K. A., Church, G. M., Grishin, D., Obbad, K., Barkovich, R. J., & Palombini, M. (2019) · BMC Medicine · doi:10.1186/s12916-019-1296-7 · Cited by 327 · see citing works
Why we need a small data paradigm
Hekler, E. B., Klasnja, P., Chevance, G., Golaszewski, N. M., Lewis, D. M., & Sim, I. (2019) · BMC Medicine · doi:10.1186/s12916-019-1366-x · Cited by 290 · see citing works
Nebeker, C., Torous, J., & Bartlett Ellis, R. J. (2019) · BMC Medicine · doi:10.1186/s12916-019-1377-7 · Cited by 241 · see citing works
Who Owns the Data? Open Data for Healthcare
Kostkova, P., Brewer, H., de Lusignan, S., Fottrell, E., Goldacre, B., Hart, G., Koczan, P., Knight, P., Marsolier, C., McKendry, R. A., et al. (2016) · Frontiers in Public Health · doi:10.3389/fpubh.2016.00007 · Cited by 230 · see citing works
Phenome-Wide Association Studies as a Tool to Advance Precision Medicine
Denny, J. C., Bastarache, L. A., & Roden, D. M. (2016) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090314-024956 · Cited by 224 · see citing works
Goldacre, B. M., DeVito, N., Heneghan, C., Irving, F., Bacon, S., Fleminger, J., & Curtis, H. J. (2018) · BMJ · doi:10.1136/bmj.k3218 · Cited by 180 · see citing works
The eMERGE Network, Namjou, B., Lingren, T., Huang, Y., Parameswaran, S., Cobb, B. L., Stanaway, I. B., Connolly, J. J., Mentch, F. D., Benoit, B., et al. (2019) · BMC Medicine · doi:10.1186/s12916-019-1364-z · Cited by 175 · see citing works
Self-citationContactless cardiac arrest detection using smart devices
Chan, J., Rea, T. D., Gollakota, S., & Sunshine, J. E. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0128-7 · Cited by 120 · see citing works
Philosophical Approaches to the Nursing Informatics Data-Information-Knowledge-Wisdom Framework
Matney, S. A., Brewster, P. J., Sward, K. A., Cloyes, K. G., & Staggers, N. (2011) · Advances in Nursing Science · doi:10.1097/ans.0b013e3182071813 · Cited by 75 · see citing works
The BMJ requires data sharing on request for all trials
Loder, E., & Groves, T. (2015) · BMJ · doi:10.1136/bmj.h2373 · Cited by 70 · see citing works
Data management and sharing policy: the first step towards promoting data sharing
Waithira, N., Mutinda, B., & Cheah, P. Y. (2019) · BMC Medicine · doi:10.1186/s12916-019-1315-8 · Cited by 68 · see citing works
Medication management support in diabetes: a systematic assessment of diabetes self-management apps
Huang, Z., Lum, E., Jimenez, G., Semwal, M., Sloot, P., & Car, J. (2019) · BMC Medicine · doi:10.1186/s12916-019-1362-1 · Cited by 66 · see citing works
Self-citationData, Information, Evidence, and Knowledge: A Proposal for Health Informatics and Data Science
Dammann, O. (2019) · Online Journal of Public Health Informatics · doi:10.5210/ojphi.v10i3.9631 · Cited by 56 · see citing works
Pate, A., Emsley, R., Ashcroft, D. M., Brown, B. C., & van Staa, T. P. (2019) · BMC Medicine · doi:10.1186/s12916-019-1368-8 · Cited by 52 · see citing works
Defining Phenotypes from Clinical Data to Drive Genomic Research
Robinson, J. R., Wei, W., Roden, D. M., & Denny, J. C. (2018) · Annual Review of Biomedical Data Science · doi:10.1146/annurev-biodatasci-080917-013335 · Cited by 48 · see citing works
Sharing all types of clinical data and harmonizing journal standards
Barbui, C. (2016) · BMC Medicine · doi:10.1186/s12916-016-0612-8 · Cited by 36 · see citing works
Time for sharing data to become routine: the seven excuses for not doing so are all invalid
Smith, R. W., & Roberts, I. (2016) · F1000Research · doi:10.12688/f1000research.8422.1 · Cited by 19 · see citing works
Pate, A., Emsley, R., Ashcroft, D. M., Brown, B. C., & van Staa, T. P. (2019) · BMC Medicine · doi:10.1186/s12916-019-1404-8 · Cited by 3 · see citing works
Flagged first, then by citations
1 of the 34 references couldn’t be matched to a known paper.
Cited by
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The ethics of AI in health care: A mapping review
Morley, J., Machado, C. C. V., Burr, C., Cowls, J., Joshi, I., Taddeo, M., & Floridi, L. (2020) · Social Science & Medicine · doi:10.1016/j.socscimed.2020.113172 · Cited by 1,105 · see citing works
Artificial Intelligence in Biological Sciences
Bhardwaj, A., Kishore, S., & Pandey, D. K. (2022) · Life · doi:10.3390/life12091430 · Cited by 165 · see citing works
Artificial intelligence and innovation capability: A dynamic capabilities perspective
Gao, Y., Liu, S., & Yang, L. (2025) · International Review of Economics & Finance · doi:10.1016/j.iref.2025.103923 · Cited by 177 · see citing works
Franco D’Souza, R., Mathew, M., Mishra, V., & Surapaneni, K. M. (2024) · Medical Education Online · doi:10.1080/10872981.2024.2330250 · Cited by 147 · see citing works
The Science of Learning Health Systems: Scoping Review of Empirical Research
Ellis, L. A., Sarkies, M., Churruca, K., Dammery, G., Meulenbroeks, I., Smith, C. L., Pomare, C., Mahmoud, Z., Zurynski, Y. A., & Braithwaite, J. (2022) · JMIR Medical Informatics · doi:10.2196/34907 · Cited by 88 · see citing works
Chen, Y., Stavropoulou, C., Narasinkan, R., Baker, A., & Scarbrough, H. (2021) · BMC Health Services Research · doi:10.1186/s12913-021-06861-y · Cited by 87 · see citing works
Management of Medico-Legal Risks in Digital Health Era: A Scoping Review
Oliva, A., Grassi, S., Vetrugno, G., Rossi, R., Morte, G. D., Pinchi, V., & Caputo, P. M. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2021.821756 · Cited by 83 · see citing works
Brufau, S. R., Wyatt, K. D., Boyum, P., Mickelson, M. M., Moore, M., & Cognetta-Rieke, C. (2020) · Applied Clinical Informatics · doi:10.1055/s-0040-1715827 · Cited by 89 · see citing works
Oosterhoff, J. H. F., & Doornberg, J. N. (2020) · EFORT Open Reviews · doi:10.1302/2058-5241.5.190092 · Cited by 81 · see citing works
Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)
Lee, J. W., Maria‐Solano, M. A., Vu, T. N. L., Yoon, S.-H., & Choi, S. (2022) · Biochemical Society Transactions · doi:10.1042/bst20211240 · Cited by 77 · see citing works
Leading with AI in critical care nursing: challenges, opportunities, and the human factor
Hassan, E. A., & El-Ashry, A. M. (2024) · BMC Nursing · doi:10.1186/s12912-024-02363-4 · Cited by 72 · see citing works
Rodriguez-Villa, E., & Torous, J. B. (2019) · BMC Medicine · doi:10.1186/s12916-019-1447-x · Cited by 71 · see citing works
The Debate on the Ethics of AI in Health Care: a Reconstruction and Critical Review
Morley, J., Machado, C., Burr, C., Cowls, J., Taddeo, M., & Floridi, L. (2019) · SSRN Electronic Journal · doi:10.2139/ssrn.3486518 · Cited by 66 · see citing works
Reporting guidelines for artificial intelligence in healthcare research
Ibrahim, H. F., Liu, X., & Denniston, A. K. (2021) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.13943 · Cited by 63 · see citing works
Rise of the Machines: Artificial Intelligence and the Clinical Laboratory
Haymond, S., & McCudden, C. R. (2021) · The Journal of Applied Laboratory Medicine · doi:10.1093/jalm/jfab075 · Cited by 59 · see citing works
Kanzler, C. M., Rinderknecht, M. D., Schwarz, A., Lamers, I., Gagnon, C., Held, J. P. O., Feys, P., Luft, A. R., Gassert, R., & Lambercy, O. (2020) · npj Digital Medicine · doi:10.1038/s41746-020-0286-7 · Cited by 54 · see citing works
Big data in the healthcare system: a synergy with artificial intelligence and blockchain technology
Pablo, R. G. J., Díaz-Peregrino, R., SOTO-ULLOA, V., GALVAN-REMIGIO, I., Paul, C., & Ogando‐Rivas, E. (2021) · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics · doi:10.1515/jib-2020-0035 · Cited by 52 · see citing works
Updates in deep learning research in ophthalmology
Ng, W. Y., Zhang, S., Wang, Z., Ong, C., Gunasekeran, D. V., Lim, G. Y. S., Zheng, F., Tan, S. C. Y., Tan, G. S. W., Rim, T. H., et al. (2021) · Clinical Science · doi:10.1042/cs20210207 · Cited by 49 · see citing works
The Challenges of Big Data for Research Ethics Committees: A Qualitative Swiss Study
Ferretti, A., Ienca, M., Velarde, M. R., Hurst, S., & Vayena, E. (2021) · Journal of Empirical Research on Human Research Ethics · doi:10.1177/15562646211053538 · Cited by 47 · see citing works
Xoxi, E., Facey, K. M., & Cicchetti, A. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.699466 · Cited by 43 · see citing works
The Ethics of AI in Health Care: A Mapping Review
Morley, J., Machado, C. C. V., Burr, C., Cowls, J., Joshi, I., Taddeo, M., & Floridi, L. (2020) · Philosophical studies series · doi:10.1007/978-3-030-81907-1_18 · Cited by 141 · see citing works
A typology of quantitative approaches to discovery
Dolničar, S., Zinn, A. K., & Demeter, C. (2023) · Annals of Tourism Research · doi:10.1016/j.annals.2023.103704 · Cited by 41 · see citing works
Artificial intelligence and the future of life sciences
Leite, M. L., Costa, L. S. D. L., Cunha, V. A., Kreniski, V., Filho, M. D. O. B., da Cunha, N. B., & Costa, F. F. (2021) · Drug Discovery Today · doi:10.1016/j.drudis.2021.07.002 · Cited by 46 · see citing works
Artificial Intelligence, Data Sensors and Interconnectivity: Future Opportunities for Heart Failure
Bächtiger, P., Plymen, C. M., Pabari, P., Howard, J. P., Whinnett, Z. I., Opoku, F., Janering, S., Faisal, A. A., Francis, D. P., & Peters, N. S. (2020) · Cardiac failure review · doi:10.15420/cfr.2019.14 · Cited by 39 · see citing works
Wang, S., Hou, Y., Li, X., Meng, X., Zhang, Y., & Wang, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.765435 · Cited by 37 · see citing works
Shaping a data-driven era in dementia care pathway through computational neurology approaches
Wong‐Lin, K., McClean, P. L., McCombe, N., Kaur, D., Sánchez‐Bornot, J. M., Gillespie, P., Todd, S., Finn, D. P., Joshi, A., Kane, J. P. M., et al. (2020) · BMC Medicine · doi:10.1186/s12916-020-01841-1 · Cited by 37 · see citing works
Challenges facing AI and Big data for Resource-poor Healthcare System
Kaur, A., Garg, R., & Gupta, P. (2021) · International Conference on Electronics and Sustainable Communication Systems (ICESC) · doi:10.1109/icesc51422.2021.9532955 · Cited by 34 · see citing works
Digital Transformation Led by Nurses and Nursing Managers’ Priorities: A Qualitative Study
Martínez, O. N., & Leyva‐Moral, J. M. (2024) · Journal of Nursing Management · doi:10.1155/2024/8873127 · Cited by 33 · see citing works
Sensing gastric cancer via point‐of‐care sensor breath analyzer
Leja, M., Kortelainen, J. M., Poļaka, I., Turppa, E., Mitrovics, J., Padilla, M., Mochalski, P., Shuster, G., Pohle, R., Kashanin, D., et al. (2021) · Cancer · doi:10.1002/cncr.33437 · Cited by 33 · see citing works
The application of artificial intelligence in hepatology: A systematic review
Balsano, C., Alisi, A., Brunetto, M. R., Invernizzi, P., Burra, P., Piscaglia, F., Alvaro, D., Bonino, F., Carbone, M., Faita, F., et al. (2021) · Digestive and Liver Disease · doi:10.1016/j.dld.2021.06.011 · Cited by 32 · see citing works
Lennerz, J. K., Salgado, R., Kim, G. E., Sirintrapun, S. J., Thierauf, J. C., Singh, A., Indave, I., Bard, A., Weissinger, S. E., Heher, Y. K., et al. (2023) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2022-1151 · Cited by 29 · see citing works
Artificial Intelligence-Based Opportunities in Liver Pathology—A Systematic Review
Allaume, P., Rabilloud, N., Turlin, B., Bardou‐Jacquet, E., Loréal, O., Caldéraro, J., Khene, Z., Acosta, O., de Crevoisier, R., Rioux-Leclercq, N. C., et al. (2023) · Diagnostics · doi:10.3390/diagnostics13101799 · Cited by 29 · see citing works
Bednorz, A., Mak, J. K. L., Jylhävä, J., & Religa, D. (2023) · Clinical Interventions in Aging · doi:10.2147/cia.s400887 · Cited by 24 · see citing works
Enhancing Artificial Intelligence with Indigenous Wisdom
Williams, D. H., & Shipley, G. P. (2021) · Open Journal of Philosophy · doi:10.4236/ojpp.2021.111005 · Cited by 24 · see citing works
Artificial Intelligence in the healthcare of older people
Mukaetova-Ladinska, E. B., Harwood, T. G., & Maltby, J. (2020) · Archives of Psychiatry and Mental Health · doi:10.29328/journal.apmh.1001011 · Cited by 21 · see citing works
Khamisy‐Farah, R., Gilbey, P., Furstenau, L. B., Sott, M. K., Farah, R. E., Viviani, M., Bisogni, M., Kong, J. D., Ciliberti, R., & Bragazzi, N. L. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18178989 · Cited by 20 · see citing works
Health Data Sharing towards Knowledge Creation
Elvas, L. B., Ferreira, J. C., Dias, M. S., & Rosário, L. B. (2023) · Systems · doi:10.3390/systems11080435 · Cited by 19 · see citing works
Muharremi, G., Meçani, R., & Muka, T. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm14010053 · Cited by 12 · see citing works
Predicting patient outcomes in psychiatric hospitals with routine data: a machine learning approach
Wolff, J., Gary, A., Jung, D., Normann, C., Kaier, K., Binder, H., Domschke, K., Klimke, A., & Franz, M. (2020) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-020-1042-2 · Cited by 20 · see citing works
Targeting cellular senescence to combat cancer and ageing
Wang, C., Hao, X., & Zhang, R. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13266 · Cited by 19 · see citing works
Levy, J., Chan, N., Marotti, J. D., Kerr, D. A., Gutmann, E. J., Glass, R. E., Dodge, C. P., Suriawinata, A. A., Christensen, B. C., Liu, X., et al. (2023) · Cancer Cytopathology · doi:10.1002/cncy.22732 · Cited by 17 · see citing works
Umer, M., Naveed, A., Maryam, Q., Malik, A. R., Bashir, N., & Kandel, K. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001957 · Cited by 17 · see citing works
Innovation Resistance and Resource Allocation Strategy of Medical Information Digitalization
Lu, W.-C., Tsai, I.-C., Wang, K.-C., Tang, T.-A., Li, K.-C., Ke, Y.-C., & Chen, P.-T. (2021) · Sustainability · doi:10.3390/su13147888 · Cited by 17 · see citing works
Sasaki, N., Yamaguchi, N., Okumura, A. J., Yoshida, M., Sugawara, H., Shin, J., Kunisawa, S., & Imanaka, Y. (2020) · Implementation Science · doi:10.1186/s13012-020-01056-1 · Cited by 16 · see citing works
Smartphones within Psychological Science
Ellis, D. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108671408 · Cited by 14 · see citing works
An Asian Body to Tackle Cancers in Asia – The Asian National Cancer Centers Alliance
Gatellier, L., Matsuda, T., Sabapathy, K., Dai, M., Dewi, L. K. M., Huong, T. T., Kardinah, K., Thuân, T. V., Park, J. B., He, J., et al. (2020) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2020.21.5.1207 · Cited by 14 · see citing works
Scheduling of Remote Monitoring for Peritoneal Dialysis Patients
Virzì, G. M., Morisi, N., Manani, S. M., Tantillo, I., Barajas, J. D. G., Díaz-Villavicencio, B., Castiglione, C., Alfano, G., Donati, G., & Zanella, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020406 · Cited by 13 · see citing works
The Debate on the Ethics of AI in Health Care: a Reconstruction and Critical ReviewPreprint
Morley, J. (2019) · doi:10.31219/osf.io/n7y2g · Cited by 12 · see citing works
Eweje, F. R., Byun, S., Chandra, R., Hu, F., Kamel, I. R., Zhang, P. J., Jiao, Z., & Bai, H. X. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.44742 · Cited by 12 · see citing works
Crossing the AI Chasm in Neurocritical Care
Cascella, M., Montomoli, J., Bellini, V., Vittori, A., Biancuzzi, H., Mas, F. D., & Bignami, E. G. (2023) · Computers · doi:10.3390/computers12040083 · Cited by 12 · see citing works
Adeghe, E. P., Okolo, C. A., & Ojeyinka, O. T. (2024) · Open Access Research Journal of Life Sciences · doi:10.53022/oarjls.2024.7.1.0026 · Cited by 12 · see citing works
Big Data/AI in Neurocritical Care: Maybe/Summary
Suárez, J. I. (2021) · Neurocritical Care · doi:10.1007/s12028-021-01422-x · Cited by 12 · see citing works
Temporal uncertainty in disease diagnosis
Hofmann, B. (2023) · Medicine Health Care and Philosophy · doi:10.1007/s11019-023-10154-y · Cited by 14 · see citing works
Dittrich, F., Back, D. A., Harren, A. K., Jäger, M., Landgraeber, S., Reinecke, F., & Beck, S. (2019) · JMIR mhealth and uhealth · doi:10.2196/16403 · Cited by 11 · see citing works
ChatGPT: First glance from a perspective of clinical pharmacology
Krumborg, J. R., Mikkelsen, N., Damkier, P., Ennis, Z. N., Henriksen, D. P., Lillevang‐Johansen, M., Pedersen, S. A., & Bergmann, T. K. (2023) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13879 · Cited by 11 · see citing works
Data like any other? Sexual and reproductive health, Big Data and the Sustainable Development Goals
Hammond, N., & Moretti, A. (2023) · Sexualities · doi:10.1177/13634607231152599 · Cited by 9 · see citing works
Alsahafi, Z., & Baashar, A. (2025) · Cureus · doi:10.7759/cureus.83437 · Cited by 11 · see citing works
Xie, Y., Ding, H., Du, X., Chai, C., Wei, X., Sun, J., Zhuo, C., Wang, L., Li, J., Tian, H., et al. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac096 · Cited by 9 · see citing works
Applications of Big Data and AI-Driven Technologies in CADD (Computer-Aided Drug Design)
Seo, S., & Lee, J. W. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3441-7_16 · Cited by 9 · see citing works
Xia, F., Ren, J., Liu, L., Cui, Y., & He, Y. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1515094 · Cited by 11 · see citing works
Trusted Artificial Intelligence: On the Use of Private Data
Jastroch, N. (2020) · IFIP advances in information and communication technology · doi:10.1007/978-3-030-62807-9_52 · Cited by 8 · see citing works
de Oliveira, M. M. R., Quittes, L., Costa, P. H. V., Ramos, T. M., Rodrigues, A. C. F., Nicolato, A. A., Malheiros, J. A., & Machado, C. J. (2021) · Neurosurgical Review · doi:10.1007/s10143-021-01663-6 · Cited by 8 · see citing works
Proposing Technology-Enhanced Wisdom
Vyas, P., & Gephart, S. M. (2025) · Advances in Nursing Science · doi:10.1097/ans.0000000000000585 · Cited by 7 · see citing works
Revolution of Artificial Intelligence in Computational Chemistry Breakthroughs
Bendi, A., Goswami, S., Banik, P., Chauhan, V., Raghav, N., & Chinmay (2024) · Chemistry Africa · doi:10.1007/s42250-024-00976-5 · Cited by 7 · see citing works
Kashkoush, A. I., El-Abtah, M. E., Achey, R., Winkelman, R., Glauser, G., Patterson, T. E., Moore, N. Z., Kshettry, V. R., Gomes, J. A., & Bain, M. (2023) · Operative Neurosurgery · doi:10.1227/ons.0000000000000845 · Cited by 5 · see citing works
Digitale Gesundheit: Was ändert sich für den Gesundheitsbegriff?
Wieser, B. (2019) · Österreichische Zeitschrift für Soziologie · doi:10.1007/s11614-019-00389-6 · Cited by 5 · see citing works
Editorial: Artificial intelligence: applications in clinical medicine
Levy, J., Madrigal, E., & Vaickus, L. J. (2023) · Frontiers in Medical Technology · doi:10.3389/fmedt.2023.1206969 · Cited by 5 · see citing works
Xu, X., Xiong, X., He, Z., Lü, Q., & Wang, L. (2025) · Talanta · doi:10.1016/j.talanta.2025.128724 · Cited by 4 · see citing works
Thompson, A., Bartle, V., Remfry, E., Reynolds, D. J., Barnes, M. R., Reynolds, N. J., & Hanratty, B. (2025) · Health Expectations · doi:10.1111/hex.70490 · Cited by 4 · see citing works
Bojnordi, A. J. J., Nezhad, M. Z., Bagheri, R., Bazrafshan, M., & Sohrabi, B. (2025) · Discover Health Systems · doi:10.1007/s44250-025-00204-y · Cited by 4 · see citing works
Zhang, Y., Ding, X., & Hu, F. (2020) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1621/1/012108 · Cited by 4 · see citing works
OHF: An Ontology Based Framework for Healthcare
Dhiman, S., Thukral, A., & Bedi, P. (2022) · Communications in computer and information science · doi:10.1007/978-3-030-95711-7_28 · Cited by 4 · see citing works
Buhr, L., & Schicktanz, S. (2022) · Big Data & Society · doi:10.1177/20539517221092653 · Cited by 4 · see citing works
Clinical performance of automated machine learning: a systematic reviewPreprint
Thirunavukarasu, A. J., Elangovan, K., Gutiérrez, L., Hassan, R., Li, Y., Tan, T. F., Cheng, H., Teo, Z. L., Lim, G., & Ting, D. S. W. (2023) · medRxiv · doi:10.1101/2023.10.26.23297599 · Cited by 4 · see citing works
Ethical Issues Raised by Artificial Intelligence and Big Data in Population Health: A Scoping Review
Couture, V., Roy, M.-C., Dez, E., Tremblay, F., & Bélisle-Pipon, J.-C. (2025) · Frontiers in Sociology · doi:10.3389/fsoc.2025.1536389 · Cited by 3 · see citing works
Stavropoulou, C., Scarbrough, H., Rawlinson, J., Cui, M., Baldwin, D., & Woznitza, N. (2026) · Frontiers in Digital Health · doi:10.3389/fdgth.2026.1736911 · Cited by 3 · see citing works
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Munyengeterwa, T. S., Richards, M. B., & Eaton, J. B. (2023) · Advances in environmental engineering and green technologies book series · doi:10.4018/978-1-6684-6366-6.ch006 · Cited by 3 · see citing works
Artificial Intelligence in endoscopy: A future poll
Elshaarawy, O., Alboraie, M. A. A., & El‐Kassas, M. (2024) · Arab Journal of Gastroenterology · doi:10.1016/j.ajg.2023.11.008 · Cited by 3 · see citing works
Algorithmic Experience: Exploring the Potential of AI Technologies for Medical Knowledge Integration
Lösch, L., & Zuiderent‐Jerak, T. (2024) · Springer eBooks · doi:10.1007/978-3-031-52049-5_4 · Cited by 3 · see citing works
Fu, Y., Sun, Y., Zhang, S., Jia, Y., Zhang, J., Huang, L., Xu, Q., Zhang, Y., Chen, S., Wu, X., et al. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108485 · Cited by 3 · see citing works
Prasanna, A., Jing, B., Plopper, G. E., Miller, K. K., Sanjak, J. S., Feng, A., Prezek, S., Vidyaprakash, E., Thovarai, V., Maier, E. J., et al. (2023) · medRxiv · doi:10.1101/2023.12.11.23298687 · Cited by 4 · see citing works
Isso não é uma pirâmide: revisando o modelo clássico de dado, informação, conhecimento e sabedoria
Ribeiro, A. C. M. L., & dos Santos, C. D. (2020) · Ciência da Informação · doi:10.18225/ci.inf.v49i2.5066 · Cited by 2 · see citing works
Tang, P. P., Tam, I. L., Jia, Y., & Leung, S.-W. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-053447 · Cited by 2 · see citing works
Murphy, A. F., & Ollerenshaw, A. (2022) · Online Information Review · doi:10.1108/oir-08-2021-0403 · Cited by 2 · see citing works
(Lucewicz), A. S., Rhou, Y. J. J., Melov, S. J., Elhindi, J., Patel, S., Flood, V. M., Smith, B. J., Usherwood, T. P., McNab, J., McClean, M., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-090930 · Cited by 2 · see citing works
Wambua, A., Maurice, P. M., & Munyao, M. (2025) · Discover Education · doi:10.1007/s44217-025-00607-2 · Cited by 2 · see citing works
Kandara, O., & Kennedy, E. (2019) · Advances in educational technologies and instructional design book series · doi:10.4018/978-1-7998-1173-2.ch001 · Cited by 2 · see citing works
Huang, J., & Dang, F. (2022) · Journal of Healthcare Engineering · doi:10.1155/2022/2612074 · Cited by 2 · see citing works
RetractedAshkani‐Esfahani, S., & Ebrahimi, A. (2022) · Journal of Foot and Ankle Surgery (Asia Pacific) · doi:10.5005/jp-journals-10040-1266 · Cited by 2 · see citing works
Personality and Individual Differences
Ellis, D. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108671408.006 · Cited by 2 · see citing works
Ellis, D. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108671408.003 · Cited by 2 · see citing works
Ndemo, B. (2025) · Research Square · doi:10.21203/rs.3.rs-6572611/v1 · Cited by 2 · see citing works
Complexity of Patient Data in Primary Care Practice
Švab, I. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11590-9 · Cited by 1 · see citing works
Evidence and clinical trials in Endourology: where are we going
Donaldson, J. F., & McClinton, S. (2021) · Current Opinion in Urology · doi:10.1097/mou.0000000000000851 · Cited by 1 · see citing works
From Experience to Experience: Key Insights for Improved Interaction with AI in Radiology
Fang, N., Pluyter, J. R., Bakker, S., Jacobs, I., Luyer, M. D. P., Nederend, J., Raijmakers, J., Chen, L.-L., & Funk, M. (2024) · CHI Conference Extended Abstracts on Human Factors in Computing Systems (CHI EA) · doi:10.1145/3613905.3650779 · Cited by 1 · see citing works
Perspective Chapter: The Role of Artificial Intelligence in Medical Curriculum Design
Naeim, M. (2026) · Education and human development · doi:10.5772/intechopen.1012732 · Cited by 1 · see citing works
Clinical performance of automated machine learning: A systematic review
Thirunavukarasu, A. J., Elangovan, K., Gutiérrez, L., Hassan, R., Li, Y., Tan, T. F., Cheng, H., Teo, Z. L., Lim, G., & Ting, D. S. W. (2024) · Annals of the Academy of Medicine Singapore · doi:10.47102/https://doi.org/10.47102/annals-acadmedsg.2023113 · Cited by 16 · see citing works
The Ethics of AI in Medical Research: A Call for Open and Honest Discussion
Tahseen, S., Memon, M. A., Kamran, S. M., & Pathan, K. T. (2024) · Liaquat Medical Research Journal · doi:10.38106/lmrj.2024.6.2-07 · Cited by 1 · see citing works
Grant, N. V., Bejan, A., Kunze, C., & Burkhardt, H. (2024) · Mensch und Computer (MuC) · doi:10.1145/3670653.3677483 · Cited by 1 · see citing works
RETRACTED: Lightweight multiparty privacy set intersection protocol for internet of medical things
Shan, Z., Zhang, L., Wu, Q., & Rezaeibagha, F. (2025) · Journal of Industrial Information Integration · doi:10.1016/j.jii.2025.100863 · Cited by 1 · see citing works
Retracted
- Authors
- Car, J., Sheikh, A., Wicks, P., & Williams, M. S.
- Affiliations
- Nanyang Technological University (SG)
- University of Edinburgh (GB)
- PatientsLikeMe (United States) (US)
- Corresponding author
- Wicks, Paul
- Venue
- BMC Medicine
- Published
- 2019-07-17
- Volume
- 17
- Issue
- 1
- Pages
- 143-143
- ISSN
- 1741-7015 (ISSN-L)
- PMC
- PMC6636050
- OpenAlex
- W2957812729
- Cited by
- 126
- References
- 34
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 16 · 2023: 17 · 2022: 15 · 2021: 22 · 2020: 27 · 2019: 6
- FWCI
- 5.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DR-NTU (Nanyang Technological University) (submittedVersion, cc-by)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Keywords
- big data, artificial intelligence, real-world data, electronic health records, genomic medicine, digital health, data sharing ethics, privacy, data security, health equity, population health
- MeSH terms
- Big Data, Algorithms, Artificial Intelligence, Bioethics, Delivery of Health Care, Humans, Health Knowledge, Attitudes, Practice, Knowledge, Genomics, Information Dissemination, Biomedical Research, Electronic Health Records
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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