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Cited by 459

The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.

Long noncoding RNAs in cancer: mechanisms of action and technological advancements

Open access
Bartonicek, Nenad, Maag, Jesper L. V., Dinger, Marcel E.·2016·Molecular Cancer

Abstract

The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to being defined as a category of genetic elements, leaving its mark on the field of cancer biology. With the current number of curated lncRNAs increasing by 10,000 in the last five years, the field is moving from annotation of lncRNA expression in various tumours to understanding their importance in the key cancer signalling networks and characteristic behaviours. Here, we summarize the previously identified as well as recently discovered mechanisms of lncRNA function and their roles in the hallmarks of cancer. Furthermore, we identify novel technologies for investigation of lncRNA properties and their function in carcinogenesis, which will be important for their translation to the clinic as novel biomarkers and therapeutic targets.

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Metadata

Authors
Bartonicek, N., Maag, J. L. V., & Dinger, M. E.
Venue
Molecular Cancer
Published
2016-05-27
Volume
15
Issue
1
Pages
43-43
ISSN
1476-4598 (ISSN-L)
OpenAlex
W2399577914
Cited by
459
References
149
FWCI
22.93
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Long noncoding RNAs in cancer: mechanisms of action and technological advancements. https://app.cochat.ai/papers/10.1186/s12943-016-0530-6
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Bartonicek, N., Maag, J. L. V., & Dinger, M. E. (2016). Long noncoding RNAs in cancer: mechanisms of action and technological advancements. Molecular Cancer. https://doi.org/10.1186/s12943-016-0530-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.