The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Perilipins: a diversity of intracellular lipid droplet proteins
Open accessAbstract
Intracellular lipid droplets (LDs) are found in a wide variety of cell types and have been recognized as organelles with unique spherical structures. Although LDs are not stable lipid-depots, they are active sites of neutral lipid metabolism, and comprise neutral lipid or cholesterol cores surrounded by phospholipid monolayers containing specialized proteins. However, sizes and protein compositions vary between cell and tissue types. Proteins of the perilipin family have been associated with surfaces of LDs and all carry a conserved 11-mer repeat motif. Accumulating evidence indicates that all perilipins are involved in LD formation and that all play roles in LD function under differing conditions. In this brief review, we summarize current knowledge of the roles of perilipins and lipid metabolizing enzymes in a variety of mammalian cell types.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Autophagy regulates lipid metabolism
Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975
Brasaemle, D. L., Dolios, G., Shapiro, L., & Wang, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m409340200 · Cited by 804
The Surface of Lipid Droplets Is a Phospholipid Monolayer with a Unique Fatty Acid Composition
Tauchi-Sato, K., Ozeki, S., Houjou, T., Taguchi, R., & Fujimoto, T. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207712200 · Cited by 753
Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain
Urquiza, A. M. D., Liu, S., Sjöberg, M., Zetterström, R. H., Griffiths, W., Sjövall, J., & Perlmann, T. (2000) · Science · doi:10.1126/science.290.5499.2140 · Cited by 742
Tansey, J. T., Sztalryd, C., Gruia-Gray, J., Roush, D. L., Zee, J. V., Gavrilova, O., Reitman, M. L., Deng, C.-X., Li, C., Kimmel, A. R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101042998 · Cited by 734
Kaushik, S., & Cuervo, A. M. (2015) · Nature Cell Biology · doi:10.1038/ncb3166 · Cited by 714
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
Bickel, P. E., Tansey, J. T., & Welte, M. A. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.04.002 · Cited by 670
Brasaemle, D. L., Barber, T., Wolins, N. E., Serrero, G., Blanchette-Mackie, E. J., & Londos, C. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34939-7 · Cited by 644
Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice
Martinez-Botas, J., Anderson, J. B., Tessier, D., Lapillonne, A., Chang, B. H.-J., Quast, M. J., Gorenstein, D., Chen, K.-H., & Chan, L. (2000) · Nature Genetics · doi:10.1038/82630 · Cited by 581
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores.
Zechner, R., Kienesberger, P. C., Haemmerle, G., Zimmermann, R., & Lass, A. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800031-jlr200 · Cited by 576
Cited by
Regulation of intestinal lipid metabolism: current concepts and relevance to disease
Ko, C.-W., Qu, J., Black, D. D., & Tso, P. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0250-7 · Cited by 510
Lipid storage and lipophagy regulates ferroptosis
Bai, Y., Meng, L., Han, L., Jia, Y., Zhao, Y., Gao, H., Kang, R., Wang, X., Tang, D., & Dai, E. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.12.039 · Cited by 507
The ménage à trois of autophagy, lipid droplets and liver disease
Filali-Mouncef, Y., Hunter, C., Roccio, F., Zagkou, S., Dupont, N., Primard, C., Proikas-Cezanne, T., & Reggiori, F. (2022) · Autophagy · doi:10.1080/15548627.2021.1895658 · Cited by 361
Cotte, A. K., Aires, V., Fredon, M., Limagne, E., Derangère, V., Thibaudin, M., Humblin, E., Scagliarini, A., de Barros, J.-P. P., Hillon, P., et al. (2018) · Nature Communications · doi:10.1038/s41467-017-02732-5 · Cited by 359
Plant Lipid Droplets and Their Associated Proteins: Potential for Rapid Advances
Huang, A. H. C. (2018) · Plant Physiology · doi:10.1104/pp.17.01677 · Cited by 287
Metadata
- Authors
- Itabe, H., Yamaguchi, T., Nimura, S., & Sasabe, N.
- Venue
- Lipids in Health and Disease
- Published
- 2017-04-28
- Volume
- 16
- Issue
- 1
- Pages
- 83-83
- ISSN
- 1476-511X (ISSN-L)
- OpenAlex
- W2608630895
- Cited by
- 353
- References
- 88
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Perilipins: a diversity of intracellular lipid droplet proteins. https://app.cochat.ai/papers/10.1186/s12944-017-0473-y
- The paper
- Itabe, H., Yamaguchi, T., Nimura, S., & Sasabe, N. (2017). Perilipins: a diversity of intracellular lipid droplet proteins. Lipids in Health and Disease. https://doi.org/10.1186/s12944-017-0473-y
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
