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Cited by 8Multiple Sclerosis Research StudiesHealth Systems, Economic Evaluations, Quality of LifeHealth Education and Validation

Validation of the Indonesian version of multiple sclerosis quality of life-54 (MSQOL-54 INA) questionnaire

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Estiasari, Riwanti, Melani, Syarly, Kusumawardhani, A. A. A. Agung, Pangeran, David, Fajrina, Yuhyi, Maharani, Kartika, Imran, Darma·2019·Health and Quality of Life Outcomes
DOI 10.1186/s12955-019-1190-1PMC PMC6626390
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Abstract

BACKGROUND: Quality of life assessment of patients with multiple sclerosis (MS) is not routinely performed in Indonesia due to the unavailability of the validated Indonesian version of a specific instrument. The objective of this study was to transculturally adapt and validate the Indonesian version of the MSQOL-54 (MSQOL-54 INA) questionnaire. METHODS: The transcultural adaptation was conducted by performing a standardized forward-backward method. Psychometric analysis was performed by assessing the reliability (Cronbach α), internal validation (item internal consistency and item discriminant validity), and external validation by measuring the correlation with a clinical factor such as EDSS and other demographic factors. RESULTS: Reliability test with Cronbach α showed good internal consistency (> 0.7) at each component, except for health perception (0.665) and social function (0.433). Construct validity using computation of correlation coefficient showed internal consistency in accordance with the original MSQOL-54 standard dimension, except for energy and role limitation due to emotional problems components. External validation with EDSS showed negative correlation on almost all components, except for sexual function, but both composite scores were statistically significant. CONCLUSION: MSQOL-54 INA questionnaire has good internal reliability and is proven to be valid and well-accepted by Indonesian MS patients. Therefore, it can be used by Indonesian clinicians for more comprehensive MS management.

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Cited by

Sorted by citations

Authors
Estiasari, R., Melani, S., Kusumawardhani, A. A. A. A., Pangeran, D., Fajrina, Y., Maharani, K., & Imran, D.
Affiliations
University of Indonesia (ID)
Corresponding author
Estiasari, Riwanti
ORCID
Venue
Health and Quality of Life Outcomes
Publisher
Springer Science and Business Media LLC
Published
2019-07-12
Volume
17
Issue
1
Pages
120-120
ISSN
1477-7525 (ISSN-L)
DOI
10.1186/s12955-019-1190-1
PMC
PMC6626390
OpenAlex
W2960015808
Cited by
8
References
3
Citations by year
2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2
FWCI
0.55
Type
journal article
Language
en
Open access
Licence
Locations
  • Health and Quality of Life Outcomes (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Universitas Indonesia (PITTA/694/FK/2018)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Social Sciences › Education › Health Education and Validation
Keywords
multiple sclerosis, quality of life, MSQOL-54, Indonesian translation, cross-cultural adaptation, psychometric validation, reliability statistics, construct validity, Expanded Disability Status Scale, sexual function, patient-reported outcomes
MeSH terms
Adult, Female, Humans, Indonesia, Male, Middle Aged, Multiple Sclerosis, Quality of Life, Surveys and Questionnaires, Translations, Reproducibility of Results

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