The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
The interplay between m6A RNA methylation and noncoding RNA in cancer
Open accessAbstract
N6-methyladenosine (m6A) methylation, one of the most common RNA modifications, has been reported to execute important functions that affect normal life activities and diseases. Most studies have suggested that m6A modification can affect the complexity of cancer progression by regulating biological functions related to cancer. M6A modification of noncoding RNAs regulates the cleavage, transport, stability, and degradation of noncoding RNAs themselves. It also regulates cell proliferation and metastasis, stem cell differentiation, and homeostasis in cancer by affecting the biological function of cells. Interestingly, noncoding RNAs also play significant roles in regulating these m6A modifications. Additionally, it is becoming increasingly clear that m6A and noncoding RNAs potentially contribute to the clinical application of cancer treatment. In this review, we summarize the effect of the interactions between m6A modifications and noncoding RNAs on the biological functions involved in cancer progression. In particular, we discuss the role of m6A and noncoding RNAs as possible potential biomarkers and therapeutic targets in the treatment of cancers.
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Cites
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Cited by
Wu, H., Ding, X., Hu, X., Zhao, Q., Chen, Q., Sun, T., Li, Y., Guo, H., Li, M., Gao, Z., et al. (2022) · Oncogene · doi:10.1038/s41388-022-02189-x · Cited by 26
Metadata
- Authors
- Ma, S., Chen, C., Ji, X., Liu, J., Zhou, Q., Wang, G., Yuan, W., Kan, Q., & Sun, Z.
- Venue
- Journal of Hematology & Oncology
- Published
- 2019-11-22
- Volume
- 12
- Issue
- 1
- Pages
- 121-121
- ISSN
- 1756-8722 (ISSN-L)
- OpenAlex
- W2990844810
- Cited by
- 632
- References
- 124
- FWCI
- 22.06
- Type
- journal article
- Language
- en
- Open access
- gold
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- Ma, S., Chen, C., Ji, X., Liu, J., Zhou, Q., Wang, G., Yuan, W., Kan, Q., & Sun, Z. (2019). The interplay between m6A RNA methylation and noncoding RNA in cancer. Journal of Hematology & Oncology. https://doi.org/10.1186/s13045-019-0805-7
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