The DOI matches its Crossref record; 178 of the 178 references it cites were found in a registry or an index.
Role of metabolism in cancer cell radioresistance and radiosensitization methods
Open accessAbstract
BACKGROUND: Radioresistance is a major factor leading to the failure of radiotherapy and poor prognosis in tumor patients. Following the application of radiotherapy, the activity of various metabolic pathways considerably changes, which may result in the development of resistance to radiation. MAIN BODY: Here, we discussed the relationships between radioresistance and mitochondrial and glucose metabolic pathways, aiming to elucidate the interplay between the tumor cell metabolism and radiotherapy resistance. In this review, we additionally summarized the potential therapeutic targets in the metabolic pathways. SHORT CONCLUSION: The aim of this review was to provide a theoretical basis and relevant references, which may lead to the improvement of the sensitivity of radiotherapy and prolong the survival of cancer patients.
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1 retracted
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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
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Jiang, X., Wang, J., Deng, X., Xiong, F., Ge, J., Xiang, B., Wu, X., Ma, J., Zhou, M., Li, X., et al. (2019) · Molecular Cancer · doi:10.1186/s12943-018-0928-4 · Cited by 1,457
Self-citationThe MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis
Ghasemi, M., Turnbull, T., Sebastian, S., & Kempson, I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312827 · Cited by 1,333
Arab-Bafrani, Z., Zabihi, E., Jafari, S. M., Khoshbin-Khoshnazar, A., Mousavi, E., Khalili, M., & Babaei, A. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120828 · Cited by 39
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Askar, M. A., Thabet, N. M., El-sayyad, G. S., El-Batal, A. I., kodous, M. A. E., Kawamura, G., Matsuda, A., Shawi, O. E. E., Helal, H., & Abdel-Rafei, M. K. (2021) · doi:10.21203/rs.3.rs-910507/v1 · Cited by 27
Metadata
- Authors
- Tang, L., Wei, F., Wu, Y., He, Y., Shi, L., Xiong, F., Gong, Z., Guo, C., Li, X., Deng, H., Cao, K., Zhou, M., Xiang, B., Li, X., Li, Y., Li, G., Xiong, W., & Zeng, Z.
- Venue
- Journal of Experimental & Clinical Cancer Research
- Published
- 2018-04-23
- Volume
- 37
- Issue
- 1
- Pages
- 87-87
- ISSN
- 0392-9078 (ISSN-L)
- 1756-9966
- OpenAlex
- W2802832662
- Cited by
- 409
- References
- 178
- FWCI
- 12.46
- Type
- journal article
- Language
- en
- Open access
- gold
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- Tang, L., Wei, F., Wu, Y., He, Y., Shi, L., Xiong, F., Gong, Z., Guo, C., Li, X., Deng, H., Cao, K., Zhou, M., Xiang, B., Li, X., Li, Y., Li, G., Xiong, W., & Zeng, Z. (2018). Role of metabolism in cancer cell radioresistance and radiosensitization methods. Journal of Experimental & Clinical Cancer Research. https://doi.org/10.1186/s13046-018-0758-7
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