The global burden of sepsis: barriers and potential solutions

Rudd, Kristina E., Kissoon, Niranjan, Limmathurotsakul, Direk, Bory, Sotharith, Mutahunga, Birungi, Seymour, Christopher W., Angus, Derek C., West, T. Eoin·2018·Critical Care
DOI 10.1186/s13054-018-2157-z

Cited by (421)

Items 301–400 of 421

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  14. Benefits of esmolol in sepsis and septic shock in adults: a meta-analysis of randomized controlled trials
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  16. Improving the Accuracy of Sepsis Screening by Nurses in Hospitalized Older Adults: A Pilot Interventional Study
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  17. Effect of Soluble CD14 Subtype (sCD14ST)/ Presepsin and Lactate Clearance on Mortality Status In Pneumonia Patients With Sepsis
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  18. Helicobacter pylori: A Cause of Community-Acquired Pediatric Septic Shock: A Cross Sectional Study
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  19. Deficit Therapy in Children with Acute Diarrhoea and Severe Dehydration Presenting with Severe Non-Anion Gap Metabolic Acidemia: Should Bicarbonate Be an Integral Component?
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  20. Evaluation of the feasibility of the FAST-M maternal sepsis intervention in Pakistan, a protocol
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  21. Influencia del inmuno-metabolismo macrofágico en la sepsis humana: un nuevo paradigma
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  22. Bacteremia and Sepsis
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  23. Sepsis in Children in Latin America
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  24. Molecular Pathogenicity of Wild-Endotoxin Derived from Burned Patient’s Skin and Proposed Effectiveness of Calcium Channel Inhibitors
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  25. Circadian Rhythms in Septic Shock Patients
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  27. Associação entre sexo e mortalidade em pacientes com sepse em um hospital terciário do Distrito Federal
    Leonardo Jadyr Silva Rodrigues Alves, Mylena Valadares Silva, Isaac Azevedo Silva · 2022 · Programa de Iniciação Científica - PIC/UniCEUB - Relatórios de Pesquisa
  28. Study on the protective effect and mechanism of Neutralizing IL-17A with Secukinumab on severe sepsis model rats
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  29. Tuberculosis septic shock, an elusive pathophysiology and hurdles in management: A case report and review of literature
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  30. Tuberculosis septic shock, an elusive pathophysiology and hurdles in management: A case report and review of literature
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  31. Faculty Opinions recommendation of sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.
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  32. Mortality risk model to predict bacterial infection in Pediatric Intensive Care Unit
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  33. Model-Guided Design of Biological Controller for Septic Wound Healing Regulation
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  35. Agreement between qSOFA and NEWS scores in the screening of sepsis through Monte Carlo simulation
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  36. Early recognition of sepsis at the emergency department
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  37. Adult sepsis as an emerging hospital-acquired infection: Challenges and solutions
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  39. Bacterial Profile and their Antimicrobial Susceptibility Pattern in Pediatric Septicemia patients from Tertiary Care Hospital.
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  41. ASSOCIAÇÃO ENTRE SEXO E MORTALIDADE EM PACIENTES COM DIAGNÓSTICO DE SEPSE INTERNADOS EM UTI DE UM HOSPITAL TERCIÁRIO DO DISTRITO FEDERAL
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  42. Clinical Characteristics and Factors Associated with Mortality Among Children with Sepsis Admitted to Pediatric ICU at Muhimbili National Hospital in Dar es Salaam, Tanzania
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  43. The Role of GPER in Sepsis-Induced Myocardial Cell Damage and 28-Day Mortality Risk
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  44. Probabilistic Graphical Models for Evaluating the Utility of Data-Driven ICD Code Categories in Pediatric Sepsis
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  45. Using machine learning and centrifugal microfluidics at the point-of-need to predict clinical deterioration of patients with suspected sepsis within the first 24 h.
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  46. “If we manage early, we can get it right:” Healthcare Workers’ Experiences Managing Sepsis at a Kenyan Referral Hospital
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  47. "If We Manage Early, We Can Get It Right": A Descriptive Study of Healthcare Workers' Experiences Managing Sepsis at a Kenyan Referral Hospital
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  48. The causal relationship between smoking, alcohol consumption, and sepsis: A 2-sample mendelian randomized study
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  49. What problem are you solving?
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  50. A novel scoring system for evaluating mortality risk of patients with sepsis during early hospitalization
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  51. Sepsis Index as Diagnostic Marker for Sepsis in Adult Intensive Care Unit: A Cross-sectional Study
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  53. Factores sociodemográficos, comorbilidades y sepsis: la cara oculta de la luna
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  54. Pre-Referral Antibiotics and Mortality Among Adults With Sepsis in Southeast Asia: A Secondary Analysis of a Prospective Cohort Study
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  55. Social Precariousness and the Outcome of Critical Illnesses in People with HIV: A Multicenter Cohort Study
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  56. Additional file 1 of Protective effect of Secukinumab on severe sepsis model rats by neutralizing IL-17A to inhibit IKBα/NFκB inflammatory signal pathway
    Wang, Xingsheng, Zhang, Xinxin, Sun, Li, Gao, Guangsheng, Li, Yun · 2022 · Figshare
  57. Additional file 2 of Circadian rhythms in septic shock patients
    Gunnar Lachmann, Bharath Ananthasubramaniam, Viktor Alexander Wünsch, Scherfig, Lara-Marie, von Haefen, Clarissa, Cornelia Knaak, Andreas Edel, Lukas Ehlen, Barbara Koller, Anton Goldmann et al. · 2021 · Figshare
  58. Additional file 3 of Circadian rhythms in septic shock patients
    Gunnar Lachmann, Bharath Ananthasubramaniam, Viktor Alexander Wünsch, Scherfig, Lara-Marie, von Haefen, Clarissa, Cornelia Knaak, Andreas Edel, Lukas Ehlen, Barbara Koller, Anton Goldmann et al. · 2021 · Figshare
  59. Additional file 1 of Metabolomics and machine learning approaches for diagnostic and prognostic biomarkers screening in sepsis
    She, Han, Yuanlin Du, Du, Yunxia, Tan, Lei, Yang Shunxin, Luo, Xi, Qinghui Li, XIANG Xinming, Lu, Haibin, Hu, Yi et al. · 2023 · Figshare
  60. Additional file 2 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  61. Additional file 2 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  62. Additional file 4 of Diagnostic accuracy of pancreatic stone protein in patients with sepsis: a systematic review and meta-analysis
    Biwei Mai, Zhou, Lirong, Wang, Qi, Ding, Bo, Yifeng Zhan, Shanqing Qin, Naiyun Zhu, Zhuangxing Li, Lei, Zhixian · 2024 · Figshare
  63. Additional file 5 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  64. Additional file 11 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  65. Additional file 9 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  66. Additional file 3 of Evaluation of the feasibility of the FAST-M maternal sepsis intervention in Pakistan: a protocol
    Sheikh Irfan Ahmed, Raheel Sikandar, Rubina Barolia, Hanif Khowaja, Bakhtawar M., Memon, Kashif Ali, James Cheshire, Catherine Louise Dunlop, Coomarasamy, Arri, Sheikh, Lumaan, Lissauer, David · 2022 · Figshare
  67. Additional file 1 of Mortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study
    Hyun, Dong-gon, Lee, Su Yeon, Jee Hwan Ahn, Jin Won Huh, Hong, Sang-Bum, Younsuck Koh, 임채만 · 2022 · Figshare
  68. Additional file 1 of Diagnostic accuracy of pancreatic stone protein in patients with sepsis: a systematic review and meta-analysis
    Biwei Mai, Zhou, Lirong, Wang, Qi, Ding, Bo, Yifeng Zhan, Shanqing Qin, Naiyun Zhu, Zhuangxing Li, Zhixian Lei · 2024 · Figshare
  69. Additional file 9 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  70. Additional file 1 of Association of triglyceride-glucose index and delirium in patients with sepsis: a retrospective study
    Yipeng Fang, Dou, Aizhen, Shen, Yuehao, Tianyu Li, Haiying Liu, Cui, Yan, Xie, Keliang · 2024 · Figshare
  71. Additional file 3 of Association of autoimmune diseases with the occurrence and 28-day mortality of sepsis: an observational and Mendelian randomization study
    Li, Hui, Pan, Xiaojun, Sheng Zhang, Shen, Xuan, Li, Wan, Weifeng Shang, Wen, Zhenliang, SiSi Huang, Chen, Limin, Zhang, Xu et al. · 2024 · Figshare
  72. Additional file 7 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  73. Additional file 6 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Xiaodong Fang, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  74. Additional file 12 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  75. Additional file 1 of Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study
    Angriman, Federico, Patrick R. Lawler, Baiju R. Shah, Claudio M. Martin, Scales, Damon C. · 2024 · Figshare
  76. Additional file 7 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Yanyan Zhu, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  77. Additional file 1 of Effect of a tailored sepsis treatment protocol on patient outcomes in the Tikur Anbessa Specialized Hospital, Ethiopia: results of an interrupted time series analysis
    Lisa M. Puchalski Ritchie, Lemlem Beza, Debebe, Finot, Andualem Wubetie Aniley, Kathleen Gamble, Gerald Lebovic, Straus, Sharon E., Tigist Zewdu, Aklilu Azazh, Cheryl Hunchak et al. · 2022 · Figshare
  78. Additional file 2 of Association of autoimmune diseases with the occurrence and 28-day mortality of sepsis: an observational and Mendelian randomization study
    Li, Hui, Pan, Xiaojun, Sheng Zhang, Shen, Xuan, Li, Wan, Weifeng Shang, Wen, Zhenliang, SiSi Huang, Chen, Limin, Zhang, Xu et al. · 2024 · Figshare
  79. Additional file 2 of Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities
    Siân Bladon, Diane A.I. Ashiru-Oredope, Neil Cunningham, Alexander Pate, Glen Philip Martin, Xiaomin Zhong, Ellie Gilham, Colin Stewart Brown, Mariyam Mirfenderesky, Victoria Palin et al. · 2024 · Figshare
  80. Additional file 1 of Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities
    Siân Bladon, Diane A.I. Ashiru-Oredope, Neil Cunningham, Alexander Pate, Glen Philip Martin, Xiaomin Zhong, Ellie Gilham, Colin Stewart Brown, Mariyam Mirfenderesky, Victoria Palin et al. · 2024 · Figshare
  81. Additional file 1 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2023 · Figshare
  82. Additional file 1 of Protocol for a scoping review of sepsis epidemiology
    Wilcox, M. Elizabeth, Marietou Daou, Joanna Colleen Dionne, Peter Dodek, Englesakis, Marina, Allan Garland, Claire Lauzon, Osama M. Loubani, Bram N. Rochwerg, Manu Shankar‐Hari et al. · 2022 · Figshare
  83. Additional file 6 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  84. Additional file 12 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  85. Additional file 8 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  86. Additional file 1 of Evaluation of the feasibility of the FAST-M maternal sepsis intervention in Pakistan: a protocol
    Sheikh Irfan Ahmed, Raheel Sikandar, Rubina Barolia, Hanif Khowaja, Bakhtawar M., Memon, Kashif Ali, James Cheshire, Catherine Louise Dunlop, Coomarasamy, Arri, Sheikh, Lumaan, Lissauer, David · 2022 · Figshare
  87. Additional file 5 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Xiaodong Fang, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  88. Additional file 13 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  89. Additional file 1 of Hydrocortisone, ascorbic acid, and thiamine (HAT) for sepsis and septic shock: a meta-analysis with sequential trial analysis
    Weilan Na, Huili Shen, Yichu Li, Dong Qu · 2021 · Figshare
  90. Additional file 2 of Diagnostic accuracy of pancreatic stone protein in patients with sepsis: a systematic review and meta-analysis
    Biwei Mai, Zhou, Lirong, Wang, Qi, Ding, Bo, Yifeng Zhan, Shanqing Qin, Naiyun Zhu, Zhuangxing Li, Zhixian Lei · 2024 · Figshare
  91. Additional file 2 of Metabolomics and machine learning approaches for diagnostic and prognostic biomarkers screening in sepsis
    She, Han, Yuanlin Du, Du, Yunxia, Tan, Lei, Yang Shunxin, Luo, Xi, Li, Qinghui, XIANG Xinming, Lu, Haibin, Hu, Yi et al. · 2024 · Figshare
  92. Additional file 3 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Xiaodong Fang, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  93. Additional file 11 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  94. Additional file 4 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  95. Additional file 4 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  96. Additional file 10 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  97. Additional file 1 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  98. Additional file 3 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis
    Huachen Wang, Wang, Meixiang, Chen, Junlan, Hongda Hou, Guo, Zheng, Yang, Hong, Tang, Hua, Chen, Bing · 2024 · Figshare
  99. Additional file 10 of Integrating single-nucleus RNA sequencing and spatial transcriptomics to elucidate a specialized subpopulation of astrocytes, microglia and vascular cells in brains of mouse model of lipopolysaccharide-induced sepsis-associated encephalopathy
    Zhu, Yanyan, Zhang, Yin, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Fang, Xiaodong, Gong, Xiaoqian, Zhao, Pingsen · 2024 · Figshare
  100. Additional file 1 of Association of autoimmune diseases with the occurrence and 28-day mortality of sepsis: an observational and Mendelian randomization study
    Li, Hui, Pan, Xiaojun, Zhang, Sheng, Shen, Xuan, Li, Wan, Weifeng Shang, Wen, Zhenliang, SiSi Huang, Chen, Limin, Zhang, Xu et al. · 2023 · Figshare