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Cited by 266

The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.

Lamina-associated domains: peripheral matters and internal affairs

Open access
Briand, Nolwenn, Collas, Philippe·2020·Genome Biology

Abstract

At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typically repressive environments in the genome; nonetheless, we discuss findings of lamin interactions with regulatory elements of active genes, and the role lamins may play in genome regulation. We address the relationship between LADs and other genome organizers, and the involvement of LADs in laminopathies. The current data lay the basis for future studies on the significance of lamin-chromatin interactions in health and disease.

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Crossref · 10.1186/s13059-020-02003-5

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Metadata

Authors
Briand, N., & Collas, P.
Venue
Genome Biology
Published
2020-04-02
Volume
21
Issue
1
Pages
85-85
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
OpenAlex
W3015167195
Cited by
266
References
154
FWCI
10.03
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Lamina-associated domains: peripheral matters and internal affairs. https://app.cochat.ai/papers/10.1186/s13059-020-02003-5
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Briand, N., & Collas, P. (2020). Lamina-associated domains: peripheral matters and internal affairs. Genome Biology. https://doi.org/10.1186/s13059-020-02003-5

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.