The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.
Lamina-associated domains: peripheral matters and internal affairs
Open accessAbstract
At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typically repressive environments in the genome; nonetheless, we discuss findings of lamin interactions with regulatory elements of active genes, and the role lamins may play in genome regulation. We address the relationship between LADs and other genome organizers, and the involvement of LADs in laminopathies. The current data lay the basis for future studies on the significance of lamin-chromatin interactions in health and disease.
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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
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Harris, H. L., Gu, H., Olshansky, M., Wang, A., Farabella, I., Eliaz, Y., Kalluchi, A., Krishna, A., Jacobs, M., Cauer, G., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38429-1 · Cited by 184
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Metadata
- Authors
- Briand, N., & Collas, P.
- Venue
- Genome Biology
- Published
- 2020-04-02
- Volume
- 21
- Issue
- 1
- Pages
- 85-85
- ISSN
- 1465-6906 (ISSN-L)
- 1474-760X
- OpenAlex
- W3015167195
- Cited by
- 266
- References
- 154
- FWCI
- 10.03
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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