The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Trial Forge Guidance 1: what is a Study Within A Trial (SWAT)?
Open accessAbstract
Randomised trials are a central component of all evidence-informed health care systems and the evidence coming from them helps to support health care users, health professionals and others to make more informed decisions about treatment. The evidence available to trialists to support decisions on design, conduct and reporting of randomised trials is, however, sparse. Trial Forge is an initiative that aims to increase the evidence base for trial decision-making and in doing so, to improve trial efficiency.One way to fill gaps in evidence is to run Studies Within A Trial, or SWATs. This guidance document provides a brief definition of SWATs, an explanation of why they are important and some practical 'top tips' that come from existing experience of doing SWATs. We hope the guidance will be useful to trialists, methodologists, funders, approvals agencies and others in making clear what a SWAT is, as well as what is involved in doing one.
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Citations
Cites
Sully, B. G. O., Julious, S. A., & Nicholl, J. (2013) · Trials · doi:10.1186/1745-6215-14-166 · Cited by 410
Cited by
Naidoo, N., Nguyen, V. T., Ravaud, P., Young, B., Amiel, P., Schanté, D., Clarke, M., & Boutron, I. (2020) · BMC Medicine · doi:10.1186/s12916-019-1476-5 · Cited by 144
Self-citationFrampton, G. K., Shepherd, J., Pickett, K., Griffiths, G., & Wyatt, J. C. (2020) · Trials · doi:10.1186/s13063-020-04358-3 · Cited by 119
Berman, A. H., Topooco, N., Lindfors, P., Bendtsen, M., Lindner, P., Molander, O., Kraepelien, M., Sundström, C., Talebizadeh, N., Engström, K., et al. (2024) · Trials · doi:10.1186/s13063-024-07986-1 · Cited by 9
“An additional novel feature in this project is that it will encompass a secondary, embedded randomized “study within a trial” (SWAT) [26] that addresses the risk that some of the students in the target group will be less likely to improve in ordinary guided or unguided treatment, and may benefit…”
Background
Metadata
- Authors
- Treweek, S., Bevan, S., Bower, P., Campbell, M., Christie, J., Clarke, M., Collett, C., Cotton, S., Devane, D., El Feky, A., Flemyng, E., Galvin, S., Gardner, H., Gillies, K., Jansen, J., Littleford, R., Parker, A., Ramsay, C., Restrup, L., Sullivan, F., Torgerson, D., Tremain, L., Westmore, M., & Williamson, P. R.
- Venue
- Trials
- Published
- 2018-02-23
- Volume
- 19
- Issue
- 1
- Pages
- 139-139
- ISSN
- 1745-6215 (ISSN-L)
- OpenAlex
- W2788768006
- Cited by
- 298
- References
- 1
- FWCI
- 19.55
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
