Patients’ reasoning regarding the decision to participate in clinical cancer trials: an interview study
Open accessAbstract
BACKGROUND: Clinical cancer trials are crucial for the implementation of new treatments in the clinical setting, but it is equally crucial that patients are given the opportunity to make a well-informed decision about participation. The inclusion process is complex, including both oral and written information about the trial. The process of patients' decision-making regarding clinical cancer trials has not yet been sufficiently studied. This interview study aims to explore the process of patients' reasoning regarding the decision to participate in a clinical cancer trial. METHODS: The study is based on 27 individual face-to-face interviews with patients who had decided to participate in a clinical cancer trial. The interviews were audio-recorded and transcribed verbatim and then analysed using inductive content analysis. RESULTS: Content analysis revealed 17 subthemes grouped into five themes: (1) an unhesitating decision to participate; (2) a decision based on flimsy grounds and guided by emotion; (3) feeling safe and secure with my decision; (4) faced with a choice versus what choice do I have? and (5) hoping for help while helping others. The decision to participate in a clinical cancer trial was often immediate and guided by emotions, based on a trusting relationship with healthcare personnel rather than on careful reading of written information. Palliative patients, in particular, sometimes had unrealistic beliefs about the effectiveness of the trial treatment. CONCLUSIONS: It is vital that the decision to participate in a clinical cancer trial is preceded by an honest dialogue about possible positive and negative effects of the trial treatments, including other options such as supportive care in the palliative setting. Our findings also raise the questions of how important written information is for the decision-making process and also whether genuine informed consent is possible. To reach a higher degree of informed consent, it is most important that the oral information is given in a thorough and unbiased manner.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Trust in healthcare professionals makes patients feel safe and secure when deciding to sign up for a trial.
“This finding mirrors why people decide to take part in trials in the first place, as trust in healthcare professionals makes patients feel safe and secure when deciding to sign up for a trial [13].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Lincoln, Y. S., Guba, E. G., & Pilotta, J. J. (1985) · International Journal of Intercultural Relations · doi:10.1016/0147-1767(85)90062-8 · Cited by 45,787 · see citing works
Graneheim, U. H., & Lundman, B. (2004) · Nurse Education Today · doi:10.1016/j.nedt.2003.10.001 · Cited by 20,772 · see citing works
(2011) · Cited by 14,317 · see citing works
Cook, R. J., Dickens, B. M., & Fathalla, M. F. (2003) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199241323.003.0025 · Cited by 10,813 · see citing works
Strategies for ensuring trustworthiness in qualitative research projects
Shenton, A. K. (2004) · Education for Information · doi:10.3233/efi-2004-22201 · Cited by 9,748 · see citing works
Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
Temel, J. S., Greer, J. A., Muzikansky, A., Gallagher, E. R., Admane, S., Jackson, V. A., Dahlin, C. M., Blinderman, C. D., Jacobsen, J., Pirl, W. F., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000678 · Cited by 7,482 · see citing works
Dual-Processing Accounts of Reasoning, Judgment, and Social Cognition
Evans, J. S. B. T. (2008) · Annual Review of Psychology · doi:10.1146/annurev.psych.59.103006.093629 · Cited by 5,137 · see citing works
The qualitative research interview
DiCicco‐Bloom, B., & Crabtree, B. F. (2006) · Medical Education · doi:10.1111/j.1365-2929.2006.02418.x · Cited by 4,995 · see citing works
Bryan, H., Carpenter, C., & Hoult, S. (2010) · SAGE Publications Ltd eBooks · doi:10.4135/9781446251607.n8 · Cited by 4,174 · see citing works
(2001) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2001.tb01222.x · Cited by 3,515 · see citing works
Methodological challenges in qualitative content analysis: A discussion paper
Graneheim, U. H., Lindgren, B., & Lundman, B. M. (2017) · Nurse Education Today · doi:10.1016/j.nedt.2017.06.002 · Cited by 3,212 · see citing works
Brennen, B. S. (2017) · Routledge eBooks · doi:10.4324/9781315435978-2 · Cited by 1,487 · see citing works
Patients’ expectations about effects of chemotherapy for advanced cancer
Weeks, J. C., Catalano, P. J., Cronin, A., Finkelman, M. D., Mack, J. W., Keating, N. L., & Schrag, D. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1204410 · Cited by 1,149 · see citing works
Flory, J., & Emanuel, E. (2004) · JAMA · doi:10.1001/jama.292.13.1593 · Cited by 1,067 · see citing works
Rigour in qualitative case-study research
Houghton, C., Casey, D., Shaw, D., & Murphy, K. (2013) · Nurse Researcher · doi:10.7748/nr2013.03.20.4.12.e326 · Cited by 813 · see citing works
Quality of Informed Consent: a New Measure of Understanding Among Research Subjects
Joffe, S., Cook, E. F., Cleary, P. D., Clark, J. W., & Weeks, J. C. (2001) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/93.2.139 · Cited by 411 · see citing works
Improvement of informed consent and the quality of consent documents
Jefford, M., & Moore, R. (2008) · The Lancet Oncology · doi:10.1016/s1470-2045(08)70128-1 · Cited by 337 · see citing works
Reasons for accepting or declining to participate in randomized clinical trials for cancer therapy
Jenkins, V. A., & Fallowfield, L. J. (2000) · British Journal of Cancer · doi:10.1054/bjoc.2000.1142 · Cited by 317 · see citing works
McCann, S., Campbell, M., & Entwistle, V. A. (2010) · Trials · doi:10.1186/1745-6215-11-31 · Cited by 309 · see citing works
Mills, N., Donovan, J. L., Smith, M., Jacoby, A., Neal, D. E., & Hamdy, F. C. (2003) · Controlled Clinical Trials · doi:10.1016/s0197-2456(03)00020-5 · Cited by 142 · see citing works
Wright, J. R., Whelan, T. J., Schiff, S., Dubois, S. J., Crooks, D. L., Haines, P. T., DeRosa, D., Roberts, R. S., Gafni, A., Pritchard, K. I., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.01.187 · Cited by 139 · see citing works
Bell, J. A. H., & Balneaves, L. G. (2015) · Supportive Care in Cancer · doi:10.1007/s00520-014-2581-9 · Cited by 93 · see citing works
Madsen, S. M., Holm, S., & Riis, P. (2007) · Journal of Medical Ethics · doi:10.1136/jme.2005.015255 · Cited by 71 · see citing works
Godskesen, T., HANSSON, M. G., Nygren, P., Nordin, K., & Kihlbom, U. (2014) · European Journal of Cancer Care · doi:10.1111/ecc.12184 · Cited by 70 · see citing works
Godskesen, T., Nygren, P., Nordin, K., HANSSON, M. G., & Kihlbom, U. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-013-1891-7 · Cited by 67 · see citing works
Cox, K. (1999) · European Journal of Oncology Nursing · doi:10.1016/s1462-3889(99)80705-4 · Cited by 51 · see citing works
Bergenmar, M., Johansson, H., & Wilking, N. (2011) · Clinical Trials · doi:10.1177/1740774510384516 · Cited by 49 · see citing works
Hope and Persuasion by Physicians During Informed Consent
Miller, V. A., Cousino, M. K., Leek, A. C., & Kodish, E. D. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2014.55.2588 · Cited by 49 · see citing works
Decision Making for Cancer Clinical Trial Participation: A Systematic Review
Biedrzycki, B. A. (2010) · Oncology nursing forum · doi:10.1188/10.onf.e387-e399 · Cited by 47 · see citing works
"I Had Already Made Up My Mind"
Shannon‐Dorcy, K., & Drevdahl, D. J. (2011) · Cancer Nursing · doi:10.1097/ncc.0b013e318207cb03 · Cited by 40 · see citing works
Koitsalu, M., Eklund, M., Adolfsson, J., Grönberg, H., & Brandberg, Y. (2018) · BMC Medical Research Methodology · doi:10.1186/s12874-017-0467-5 · Cited by 40 · see citing works
on behalf of the FRAGMATIC Trial Management Group (TMG), Harrop, E. J., Noble, S., Edwards, M., Sivell, S., MOORE, B. J., & Nelson, A. (2016) · Trials · doi:10.1186/s13063-016-1460-8 · Cited by 37 · see citing works
Dear, R. F.-G., Barratt, A. L., Askie, L. M., Butow, P. N., McGeechan, K., Crossing, S., Currow, D. C., & Tattersall, M. H. N. (2012) · Annals of Oncology · doi:10.1093/annonc/mdr585 · Cited by 26 · see citing works
Factors and Outcomes of Decision Making for Cancer Clinical Trial Participation
Biedrzycki, B. A. (2011) · Oncology nursing forum · doi:10.1188/11.onf.542-552 · Cited by 22 · see citing works
Schaefer, K. M., Ladd, E. C., Gergits, M. A., & Gyauch, L. (2001) · PubMed · Cited by 22 · see citing works
Improving Informed Consent in Clinical Trials: Successful Piloting of a Decision Aid
Juraskova, I., Butow, P. N., Lopez, A.-L., Seccombe, M., Boyle, F. M., McCarthy, N. J., & Forbes, J. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.09.5471 · Cited by 20 · see citing works
Dellson, P., Nilbert, M. C., Bendahl, P.-O., MALMSTRÖM, P., & Carlsson, C.-A. (2010) · European Journal of Cancer Care · doi:10.1111/j.1365-2354.2010.01207.x · Cited by 17 · see citing works
Self-citationPatient representatives’ views on patient information in clinical cancer trials
Dellson, P., Nilbert, M. C., & Carlsson, C. (2015) · BMC Health Services Research · doi:10.1186/s12913-016-1272-2 · Cited by 15 · see citing works
Self-citationYang, J. Z., McComas, K. A., Gay, G. K., Leonard, J. P., Dannenberg, A. J., & Dillon, H. (2012) · Journal of Health Communication · doi:10.1080/10810730.2011.635774 · Cited by 14 · see citing works
Godskesen, T., & Kihlbom, U. (2017) · Journal of Oncology Practice · doi:10.1200/jop.2017.021832 · Cited by 11 · see citing works
Godskesen, T., Kihlbom, U., Nordin, K., Silén, M., & Nygren, P. (2015) · European Journal of Cancer Care · doi:10.1111/ecc.12319 · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Houghton, C., Dowling, M., Meskell, P., Hunter, A., Gardner, H., Conway, A., Treweek, S. P., Sutcliffe, K., Noyes, J., Devane, D., et al. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.mr000045.pub2 · Cited by 173 · see citing works
Houghton, C., Dowling, M., Meskell, P., Hunter, A., Gardner, H., Conway, A., Treweek, S. P., Sutcliffe, K., Noyes, J., Devane, D., et al. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.mr000045 · Cited by 131 · see citing works
Benefits of Participation in Clinical Trials: An Umbrella Review
Bouzalmate-Hajjaj, A., Massó Guijarro, P., Khan, K. S., Bueno‐Cavanillas, A., & Ibáñez, N. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215368 · Cited by 71 · see citing works
Massett, H. A., Mitchell, A. K., Alley, L., Simoneau, E., Burke, P., Han, S. H., Gallop‐Goodman, G., & McGowan, M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201463 · Cited by 46 · see citing works
Personalized and long-term electronic informed consent in clinical research: stakeholder views
Sutter, E. D., Borry, P., Geerts, D., & Huys, I. (2021) · BMC Medical Ethics · doi:10.1186/s12910-021-00675-7 · Cited by 43 · see citing works
Escritt, K., Mann, M. K., Nelson, A., & Harrop, E. J. (2022) · Trials · doi:10.1186/s13063-022-06306-9 · Cited by 37 · see citing works
Are cancer patients better off if they participate in clinical trials? A mixed methods study
Nielsen, Z. E., Eriksson, S., Harsløf, L. B. S., Petri, S., Helgesson, G., Mangset, M., & Godskesen, T. (2020) · BMC Cancer · doi:10.1186/s12885-020-06916-z · Cited by 30 · see citing works
Deciding to Enrol in a Cancer Trial: A Systematic Review of Qualitative Studies
Viljoen, B., Chambers, S. K., Dunn, J. C., Ralph, N., & March, S. (2020) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s266281 · Cited by 26 · see citing works
Patients' experiences of the decision‐making process for clinical trial participation
Gregersen, T. A., Birkelund, R., Wolderslund, M., Steffensen, K. D., & Ammentorp, J. (2022) · Nursing and Health Sciences · doi:10.1111/nhs.12933 · Cited by 24 · see citing works
Patient and Provider Perspectives Regarding Enrollment in Head and Neck Cancer Research
Shuman, A. G., Gornick, M. C., Brummel, C. V., Kent, M., Spector‐Bagdady, K., Biddle, E., Bradford, C. R., & Brenner, J. C. (2019) · Otolaryngology · doi:10.1177/0194599819889976 · Cited by 22 · see citing works
Motivations and Decision-Making of Adult Sickle Cell Patients in High-Risk Clinical Research
Cho, H. L., Kim, S. Y. H., Fitzhugh, C. D., Hsieh, M. M., Tisdale, J. F., & Grady, C. (2020) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2020.03.014 · Cited by 19 · see citing works
Nguyen, V. T., Ravaud, P., Tran, V. T., Young, B., & Boutron, I. (2022) · Journal of Medical Internet Research · doi:10.2196/29691 · Cited by 17 · see citing works
Kogan, N. R., Tolley, M., & Cohen, S. R. (2022) · Psycho-Oncology · doi:10.1002/pon.5942 · Cited by 12 · see citing works
Patient satisfaction while enrolled in clinical trials: A literature review
Tantoy, I. Y., Bright, A. N., Paelmo, E., Moreland, E. I., Trost, A. N., Pasquesi, J., Weaver, C., & D’Aquila, R. T. (2021) · Patient Experience Journal · doi:10.35680/2372-0247.1509 · Cited by 12 · see citing works
Turriff, A. E., Blain, D., Similuk, M. N., Biesecker, B. B., Wiley, H. E., Cukras, C. A., & Sieving, P. A. (2019) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2019.03.009 · Cited by 12 · see citing works
Akenine, U., Thunborg, C., Kivipelto, M., & Fallahpour, M. (2022) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s345607 · Cited by 12 · see citing works
Ong, Y. Q., Shahar, S., Safien, A. M., Ibrahim, N., Chin, A., Mangialasche, F., Kivipelto, M., & Singh, D. K. A. (2025) · BMC Public Health · doi:10.1186/s12889-024-20704-5 · Cited by 10 · see citing works
Shepherd, R. F., Bradford, A., Lieschke, M., Shackleton, K., & Hyatt, A. (2023) · Trials · doi:10.1186/s13063-023-07284-2 · Cited by 10 · see citing works
Dellson, P., Carlsson, C., Nilbert, M. C., & Jernström, H. (2019) · Trials · doi:10.1186/s13063-019-3416-2 · Cited by 10 · see citing works
Self-citationSaine, M. E., Schnellinger, E. M., Liu, M., Diamond, J. M., Crespo, M. M., Prenner, S. B., Potluri, V. S., Bermudez, C. A., Mentch, H., Moore, M., et al. (2022) · Transplantation Direct · doi:10.1097/txd.0000000000001341 · Cited by 10 · see citing works
Ethics (Informed Consent and Conflicts of Interest)
Rossfeld, K. K., Cloyd, J. M., Palmer, E. N., & Pawlik, T. M. (2020) · Success in academic surgery · doi:10.1007/978-3-030-35488-6_2 · Cited by 9 · see citing works
Patient engagement in drug development: configuring a new resource for generating innovation
Zvonareva, O. (2023) · Critical Public Health · doi:10.1080/09581596.2023.2188140 · Cited by 9 · see citing works
Akenine, U., Thunborg, C., Kivipelto, M., & Fallahpour, M. (2022) · Dove Medical Press (Taylor and Francis Group) · Cited by 9 · see citing works
Murphy, M., McCaughan, E., Carson, M. A., Donovan, M., Wilson, R. H., & Fitzsimons, D. (2020) · BMC Palliative Care · doi:10.1186/s12904-020-00661-7 · Cited by 8 · see citing works
Murphy, M., McCaughan, E., Thompson, G., Carson, M. A., Hanna, J. R., Donovan, M., Wilson, R. H., & Fitzsimons, D. (2023) · BMC Palliative Care · doi:10.1186/s12904-023-01204-6 · Cited by 7 · see citing works
Hagège, M., Canouï‐Poitrine, F., & Derbez, B. (2021) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2021.03.002 · Cited by 7 · see citing works
Corcoran, L., Friedenreich, C. M., McNeely, M. L., Culos-Reed, N. S., Bell, G. J., Dickau, L., Courneya, K. S., & Vallance, J. K. (2023) · BMC Cancer · doi:10.1186/s12885-023-10967-3 · Cited by 6 · see citing works
Liu, X., Lu, X., Zhou, W., Hahne, J., Khoshnood, K., Shi, X., Zhong, Y., & Wang, X. (2023) · Trials · doi:10.1186/s13063-023-07482-y · Cited by 6 · see citing works
Klasson, C., Frankling, M. H., Hagelin, C. L., Björkhem‐Bergman, L., & Alvariza, A. (2024) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2023-004628 · Cited by 5 · see citing works
Factors Associated With Participation in Clinical Trials Among Patients With Lupus
Harry, O., Langefeld, C. D., Crosby, L. E., & Modi, A. C. (2022) · JCR Journal of Clinical Rheumatology · doi:10.1097/rhu.0000000000001821 · Cited by 5 · see citing works
Leggett, H., Vinall-Collier, K., Csikar, J., Barber, S., Carr, R., Bhatti, A., & Pavitt, S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0296343 · Cited by 4 · see citing works
“This finding mirrors why people decide to take part in trials in the first place, as trust in healthcare professionals makes patients feel safe and secure when deciding to sign up for a trial [13].”
Toward a Science of Personalized Informed Consent in Cancer Clinical Trials
Perni, S., Hong, K., Hong, T. S., & Nipp, R. D. (2021) · JCO Oncology Practice · doi:10.1200/op.20.00975 · Cited by 4 · see citing works
Does Altruism Affect Participation in Cancer Research? A Systematic ReviewPreprint
Heo, D. H., Rodriguez, M. J., McNichol, M. C., & Moser, A. J. (2021) · Research Square · doi:10.21203/rs.3.rs-1017250/v1 · Cited by 4 · see citing works
Xu, A., & Prasad, V. K. (2022) · Journal of Comparative Effectiveness Research · doi:10.2217/cer-2021-0171 · Cited by 3 · see citing works
Wallace, C. L., Wladkowski, S. P., Juboori, R. A., Wingo, A., Coccia, K. W., Hyde, R., & Hendricks‐Ferguson, V. L. (2025) · Journal of Hospice and Palliative Nursing · doi:10.1097/njh.0000000000001140 · Cited by 2 · see citing works
Guerdoux, E., Stoebner, A., Coutant, L., Zamith‐Chavant, M., Dolbeault, S., Martinez, J., Jarlier, M., & Tosi, D. (2025) · Psycho-Oncology · doi:10.1002/pon.70291 · Cited by 2 · see citing works
Yu, S.-J., Lyu, M., Ma, H., Xu, K.-Y., Li, H.-Y., Ma, L.-L., & Ji, M.-T. (2026) · Journal of Medical Internet Research · doi:10.2196/88758 · Cited by 2 · see citing works
Feijoo-Cid, M., Marañón, A. A., Huertas‐Zurriaga, A., Rivero‐Santana, A., César, C., Fink, V. I., Fernández‐Cano, M. I., & Sued, O. G. (2023) · Health Care Analysis · doi:10.1007/s10728-023-00461-z · Cited by 2 · see citing works
Motivation to Consent and Adhere to the FORT Randomized Controlled Trial
Maheu, C., Lok, V., Galica, J., Tse, M., Maltus, E., Giguère, L., Tock, W. L., & Lebel, S. (2022) · Current Oncology · doi:10.3390/curroncol29040232 · Cited by 1 · see citing works
Predictors of consenting to participate in a clinical trial among urban cancer patients
McIntire, R. K., Keith, S. W., Nowlan, T., Butt, S., Cambareri, K., Callaghan, J., Halstead, T., Chandrasekar, T., Kelly, W. K., & Leader, A. E. (2022) · Contemporary Clinical Trials · doi:10.1016/j.cct.2022.107061 · Cited by 1 · see citing works
McPhee, N., Hughes, D., & Ristevski, E. (2025) · Trials · doi:10.1186/s13063-025-08731-y · Cited by 1 · see citing works
Therapeutic Misconception as a Problem of Nonmaleficence by Way of False Hope
Bobier, C. A. (2026) · Health Care Analysis · doi:10.1007/s10728-025-00555-w · Cited by 1 · see citing works
Paparini, S., Hayes, R., Weil, B., Nutland, W., Maatouk, I., Wi, T., Orkin, C. M., & Lewis, R. F. (2025) · BMC Medicine · doi:10.1186/s12916-024-03840-y · Cited by 1 · see citing works
Moody, L. (2020) · TSpace (University of Toronto)
Davies, L. S. C., & Drury-Smith, H. (2022) · Journal of Radiotherapy in Practice · doi:10.1017/s1460396922000139
Audisio, R. A., & Rocco, I. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21909-2.00003-x
Holland‐Hart, D., Longo, M., Bridges, S., Nixon, L. S., Hawkins, M., Crosby, T., & Nelson, A. (2025) · Trials · doi:10.1186/s13063-025-08768-z
How to Support Participants in Urogenital and Prostate Clinical Trials: A Qualitative Perspective
Roberts, N. A., Davis, I. D., Wyld, D., Goh, J. C. H., Thompson, M., Gedye, C. A., & Dhillon, H. M. (2025) · Psycho-Oncology · doi:10.1002/pon.70214
Oluyase, A. O., Ghirotto, L., Watson, H., Costantini, M., Bajwah, S., Normand, C. E. M., Tanzi, S., Bazata, J., Ryan, K., Turola, E., et al. (2025) · BMC Pulmonary Medicine · doi:10.1186/s12890-025-03862-z
Lannon, M., Hart, S., Martyniuk, A., Sharma, S. V., Acai, A., & Singh, S. K. (2025) · British Journal of Neurosurgery · doi:10.1080/02688697.2025.2569414
Escritt, K., Mann, M. K., Nelson, A., & Harrop, E. (2022) · Figshare · doi:10.6084/m9.figshare.19778347
Liu, X., Lu, X., Zhou, W., Hahne, J., Khoshnood, K., Shi, X., Zhong, Y., & Wang, X. (2024) · Figshare · doi:10.6084/m9.figshare.26602855
Escritt, K., Mann, M. K., Nelson, A., & Harrop, E. (2022) · Figshare · doi:10.6084/m9.figshare.19778344
Liu, X., Lu, X., Zhou, W., Hahne, J., Khoshnood, K., Shi, X., Zhong, Y., & Wang, X. (2024) · Figshare · doi:10.6084/m9.figshare.26602858
Engelbak Nielsen, Z., Eriksson, S., Schram Harsløf, L. B., Petri, S., Helgesson, G., Mangset, M., & Godskesen, T. E. (2020) · Figshare · doi:10.6084/m9.figshare.12276737
Understanding recruitment challenges in Swiss oncology trials: Patient voices from focus groups
Stoffel, S., Seaward, H., & Balakrishnan, A. (2026) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2026.101661
Bobier, C. A., & Hurst, D. J. (2026) · Medicine Health Care and Philosophy · doi:10.1007/s11019-026-10380-0
- Authors
- Dellson, P., Nilsson, K., Jernström, H., & Carlsson, C.
- Affiliations
- Lund University (SE)
- University of Gothenburg (SE)
- Corresponding author
- Dellson, Pia
- Venue
- Trials
- Published
- 2018-09-29
- Volume
- 19
- Issue
- 1
- Pages
- 528-528
- ISSN
- 1745-6215 (ISSN-L)
- PMC
- PMC6162882
- OpenAlex
- W2892749650
- Cited by
- 58
- References
- 42
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 5 · 2023: 6 · 2022: 15 · 2021: 7 · 2020: 8 · 2019: 3 · 2017: 1
- FWCI
- 4.28
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Trials (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Funders
- Region Skane Research Fund
- Region Skane ALF
- Gunnar Nilssons Cancerstiftelse
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Keywords
- patient decision-making, informed consent, clinical trial participation, emotional decision-making, palliative care, supportive care
- MeSH terms
- Adult, Aged, Altruism, Choice Behavior, Clinical Trials as Topic, Emotions, Female, Humans, Informed Consent, Interviews as Topic, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Neoplasms, Patient Education as Topic, Patient Selection, Trust, Research Subjects, Qualitative Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
