The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
The humanistic and economic burden of chronic wounds: a protocol for a systematic review
Open accessAbstract
BACKGROUND: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. Reviews of the evidence on the burden of illness associated with chronic wounds have not been comprehensive in scope and have not provided an assessment of the distribution of the health care costs across categories of resource use. METHODS/DESIGN: This study is a systematic review of multiple databases for studies on adult patients with chronic wounds and with the primary objective to assess the impact on health-related quality of life by category of ulcers, and associated direct and indirect costs. Eligible studies will primary be empirical studies evaluating, describing or comparing measurement of quality of life and economic impact. Two reviewers will independently screen titles and abstracts and select studies involving adults with chronic wounds. These investigators will also independently extract data using a pre-designed data extraction form. Differences in applied methodologies and uncertainties will clearly be accounted for. Conservative valuations of costs and impact on health-related quality of life will be prioritised. Variations that may depend on age distribution, the categorisation of ulcer, healthcare system etc. will be described clearly. DISCUSSION: The proposed systematic review will yield a comprehensive assessment of the humanistic and economic burden of chronic wounds in an adult population. A better understanding of the humanistic and economic burden of chronic wounds is essential for policy and planning purposes, to monitor trends in disease burden and not at least in order to estimate the real-world cost-effectiveness of new treatments and therapies. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016037496.
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Cites
PRISMA-P Group, Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., & Stewart, L. A. (2015) · Systematic Reviews · doi:10.1186/2046-4053-4-1 · Cited by 26,223
Human skin wounds: A major and snowballing threat to public health and the economy
Sen, C. K., Gordillo, G. M., Roy, S., Kirsner, R., Lambert, L., Hunt, T. K., Gottrup, F., Gurtner, G. C., & Longaker, M. T. (2009) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2009.00543.x · Cited by 2,965
Challenges in the Treatment of Chronic Wounds
Frykberg, R. G., & Banks, J. (2015) · Advances in Wound Care · doi:10.1089/wound.2015.0635 · Cited by 2,437
Guidelines for authors and peer reviewers of economic submissions to the BMJ
Drummond, M. F., & Jefferson, T. O. (1996) · BMJ · doi:10.1136/bmj.313.7052.275 · Cited by 1,827
GRADE guidelines: 5. Rating the quality of evidence—publication bias
Guyatt, G. H., Oxman, A. D., Montori, V., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., Djulbegovic, B., Atkins, D., Falck-Ytter, Y., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.01.011 · Cited by 1,819
Munn, Z., Moola, S., Riitano, D., & Lisy, K. (2014) · International Journal of Health Policy and Management · doi:10.15171/ijhpm.2014.71 · Cited by 1,479 · cited 1×
“Therefore, studies reporting health-related quality of life will be critically appraised using the Joanna Briggs Institute critical appraisal tool which is developed for prevalence data but also suitable for quality of life data that is collected with validated and well-recognised instruments [27].”
MethodAndrews, J. C., Schünemann, H. J., Oxman, A. D., Pottie, K., Meerpohl, J. J., Coello, P. A., Rind, D., Montori, V. M., Brito, J. P., Norris, S., et al. (2013) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2013.02.003 · Cited by 1,315
Gosain, A., & DiPietro, L. A. (2004) · World Journal of Surgery · doi:10.1007/s00268-003-7397-6 · Cited by 1,042
Definitions and guidelines for assessment of wounds and evaluation of healing
Lazarus, G. S., Cooper, D. M., Knighton, D. R., Margolis, D. J., Percoraro, R. E., Rodeheaver, G., & Robson, M. C. (1994) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.1994.20305.x · Cited by 580
Causes, investigation and treatment of leg ulceration
Mekkes, J. R., Loots, M. A. M., Van Der Wal, A. C., & Bos, J. D. (2003) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2003.05222.x · Cited by 381
Cited by
Human Wounds and Its Burden: An Updated Compendium of Estimates
Sen, C. K. (2019) · Advances in Wound Care · doi:10.1089/wound.2019.0946 · Cited by 1,123
Human Wound and Its Burden: Updated 2020 Compendium of Estimates
Sen, C. K. (2021) · Advances in Wound Care · doi:10.1089/wound.2021.0026 · Cited by 1,017
The humanistic and economic burden of chronic wounds: A systematic review
Olsson, M., Järbrink, K., Divakar, U., Bajpai, R., Upton, Z., Schmidtchen, A., & Car, J. (2019) · Wound Repair and Regeneration · doi:10.1111/wrr.12683 · Cited by 865
Self-citationThe Immune Functions of Keratinocytes in Skin Wound Healing
Piipponen, M., Li, D., & Landén, N. X. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228790 · Cited by 503
Chitosan and Cellulose-Based Hydrogels for Wound Management
Alven, S., & Aderibigbe, B. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249656 · Cited by 382
Metadata
- Authors
- Järbrink, K., Ni, G., Sönnergren, H., Schmidtchen, A., Pang, C., Bajpai, R., & Car, J.
- Venue
- Systematic Reviews
- Published
- 2017-01-24
- Volume
- 6
- Issue
- 1
- Pages
- 15-15
- ISSN
- 2046-4053 (ISSN-L)
- OpenAlex
- W2581581263
- Cited by
- 538
- References
- 27
- FWCI
- 6.73
- Type
- journal article
- Language
- en
- Open access
- gold
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