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Cited by 382

The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.

Chitosan and Cellulose-Based Hydrogels for Wound Management

Open access
Alven, Sibusiso, Aderibigbe, Blessing Atim·2020·International Journal of Molecular Sciences

Abstract

Wound management remains a challenge worldwide, although there are several developed wound dressing materials for the management of acute and chronic wounds. The wound dressings that are currently used include hydrogels, films, wafers, nanofibers, foams, topical formulations, transdermal patches, sponges, and bandages. Hydrogels exhibit unique features which make them suitable wound dressings such as providing a moist environment for wound healing, exhibiting high moisture content, or creating a barrier against bacterial infections, and are suitable for the management of exuding and granulating wounds. Biopolymers have been utilized for their development due to their non-toxic, biodegradable, and biocompatible properties. Hydrogels have been prepared from biopolymers such as cellulose and chitosan by crosslinking with selected synthetic polymers resulting in improved mechanical, biological, and physicochemical properties. They were useful by accelerating wound re-epithelialization and also mimic skin structure, inducing skin regeneration. Loading antibacterial agents into them prevented bacterial invasion of wounds. This review article is focused on hydrogels formulated from two biopolymers—chitosan and cellulose—for improved wound management.

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Metadata

Authors
Alven, S., & Aderibigbe, B. A.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2020-12-18
Volume
21
Issue
24
Pages
9656
ISSN
1422-0067 (ISSN-L)
OpenAlex
W3111573689
Cited by
382
References
128
FWCI
17.66
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Chitosan and Cellulose-Based Hydrogels for Wound Management. https://app.cochat.ai/papers/10.3390/ijms21249656
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Alven, S., & Aderibigbe, B. A. (2020). Chitosan and Cellulose-Based Hydrogels for Wound Management. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21249656

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