The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
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In a small, single-dose clinical trial in AD patients, after a single dose of zervimesine, levels of Aβ oligomers rose over the 24 h period assessed.
“clinical proof of mechanism was seen in a small, single-dose clinical trial in AD patients where after a single dose of zervimesine, levels of Aβ oligomers rose over the 24 h period assessed [2].”
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Citations
Cites
Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis
Viola, K. L., & Klein, W. L. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1386-3 · Cited by 628
Gobom, J., Parnetti, L., Rosa-Neto, P., Vyhnalek, M., Gauthier, S., Cataldi, S., Lerch, O., Laczo, J., Cechova, K., Clarin, M., et al. (2022) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2021-0651 · Cited by 146
Self-citationLizama, B. N., Kahle, J., Catalano, S. M., Caggiano, A. O., Grundman, M., & Hamby, M. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076251 · Cited by 54
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Flagged first, then by citations
Research works printed but not linked: 5
- Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, et al. Natural oligomers of the amyloid-β protein specifically disrupt cognitive function. Nat Neurosci. 2005;8(1):79–84. · DOI
- Izzo NJ, Yuede CM, LaBarbera KM, Limegrover CS, Rehak C, Yurko R, et al. Preclinical and clinical biomarker studies of CT1812: a novel approach to Alzheimer’s disease modification. Alzheimers Dement. 2021;17(8):1365–82. · DOI · Paper page
- Gandy S, Ehrlich ME. Moving the needle on Alzheimer’s disease with an anti-oligomer antibody. New Engl J Med. 2023;388(1):80–1. · DOI
- Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, et al. A census of human soluble protein complexes. Cell. 2012;150(5):1068–81. · DOI
- Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-β levels: Implications for a diagnostic and therapeutic biomarker. Neurology. 2007;68(9):666–9. · DOI · Paper page
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Di Caro, V., Cho, E., Thiel, J., Lizama, B. N., Koel-Simmelink, M. J. A., Pandey, K., Duong, D., Seyfried, N. T., Grundman, M., Teunissen, C. E., et al. (2026) · Alzheimer's Research & Therapy · doi:10.1186/s13195-026-02025-4 · Cited by 1
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Metadata
- Authors
- LaBarbera, K. M., Sheline, Y. I., Izzo, N. J., Yuede, C. M., Waybright, L., Yurko, R., Edwards, H. M., Gardiner, W. D., Blennow, K., Zetterberg, H., Börjesson-Hanson, A., Morgan, R., Davis, C. S., Guttendorf, R. J., Schneider, L. S., DeKosky, S., LeVine, H., Grundman, M., Caggiano, A. O., Cirrito, J. R., Catalano, S. M., & Hamby, M. E.
- ORCID
- Hamby, Mary E.
- Venue
- Translational Neurodegeneration
- Published
- 2023-05-12
- Volume
- 12
- Issue
- 1
- ISSN
- 2047-9158
- PMC
- PMC10176668
- Cited by
- 25
- References
- 3
- Language
- en
- Funders
- National Institute on Aging (AG057780)
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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