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The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Human milk microbiota profiles in relation to birthing method, gestation and infant gender

Open access
Urbaniak, Camilla, Angelini, Michelle, Gloor, Gregory B., Reid, Gregor·2016·Microbiome

Abstract

BACKGROUND: Human milk is an important source of bacteria for the developing infant and has been shown to influence the bacterial composition of the neonate, which in turn can affect disease risk later in life. Very little is known about what factors shape the human milk microbiome. The goal of the present study was to examine the milk microbiota from a range of women who delivered vaginally or by caesarean (C) section, who gave birth to males or females, at term or preterm. METHODS: Milk was collected from 39 Caucasian Canadian women, and microbial profiles were analyzed by 16S ribosomal RNA (rRNA) sequencing using the Illumina platform. RESULTS: A diverse community of milk bacteria was found with the most dominant phyla being Proteobacteria and Firmicutes and at the genus level, Staphylococcus, Pseudomonas, Streptococcus and Lactobacillus. Comparison of bacterial profiles between preterm and term births, C section (elective and non-elective) and vaginal deliveries, and male and female infants showed no statistically significant differences. CONCLUSIONS: The study revealed the diverse bacterial types transferred to newborns. We postulate that there may be a fail-safe mechanism whereby the mother is "ready" to pass along her bacterial imprint irrespective of when and how the baby is born.

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Research works printed but not linked: 4

  1. Wang X-F, Cao R-M, Li J, Wu J, Wu S-M, Chen T-X. Identification of sociodemographic and clinical factors associated with the levels of human β-defensin-1 and human β-defensin-2 in the human milk of Han Chinese. Br J Nutr. 2014;111:867–74. · doi:10.1017/s0007114513003292
  2. Zanardo V, Nicolussi S, Carlo G, Marzari F, Faggian D, Favaro F, et al. Beta endorphin concentrations in human milk. J Pediatr Gastroenterol Nutr. 2001;33:160–4. · doi:10.1097/00005176-200108000-00012
  3. Fujita M, Roth E, Lo Y-J, Hurst C, Vollner J, Kendell A. In poor families, mothers’ milk is richer for daughters than sons: a test of Trivers-Willard hypothesis in agropastoral settlements in Northern Kenya. Am J Phys Anthropol. 2012;149:52–9. · doi:10.1002/ajpa.22092
  4. Tunzi CR, Harper PA, Bar-Oz B, Valore EV, Semple JL, Watson-MacDonell J, et al. Beta-defensin expression in human mammary gland epithelia. Pediatr Res. 2000;48:30–5. · doi:10.1203/00006450-200007000-00008

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Metadata

Authors
Urbaniak, C., Angelini, M., Gloor, G. B., & Reid, G.
Venue
Microbiome
Published
2016-01-06
Volume
4
Issue
1
Pages
1-1
ISSN
2049-2618 (ISSN-L)
OpenAlex
W2225783224
Cited by
477
References
39
FWCI
45.52
Type
journal article
Language
en
Open access
gold

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Urbaniak, C., Angelini, M., Gloor, G. B., & Reid, G. (2016). Human milk microbiota profiles in relation to birthing method, gestation and infant gender. Microbiome. https://doi.org/10.1186/s40168-015-0145-y

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