From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

Everard, A., Belzer, C., Geurts, L., Ouwerkerk, J. P., Druart, C., Bindels, L. B., Guiot, Y., Derrien, M., Muccioli, G. G., Delzenne, N. M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219451110 · Cited by 4,511

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science · doi:10.1126/science.1241214 · Cited by 3,788

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C. R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y. (2015) · Cell · doi:10.1016/j.cell.2015.02.047 · Cited by 3,614

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Newgard, C. B., An, J., Bain, J. R., Muehlbauer, M. J., Stevens, R. D., Lien, L. F., Haqq, A. M., Shah, S. H., Arlotto, M., Slentz, C. A., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.02.002 · Cited by 3,165

Human Genetics Shape the Gut Microbiome

Goodrich, J. K., Waters, J. L., Poole, A. C., Sutter, J. L., Koren, O., Blekhman, R., Beaumont, M., Van Treuren, W., Knight, R., Bell, J. T., et al. (2014) · Cell · doi:10.1016/j.cell.2014.09.053 · Cited by 3,164

Metabolite profiles and the risk of developing diabetes

Wang, T. J., Larson, M. G., Vasan, R. S., Cheng, S., Rhee, E. P., McCabe, E., Lewis, G. D., Fox, C. S., Jacques, P. F., Fernandez, C., et al. (2011) · Nature Medicine · doi:10.1038/nm.2307 · Cited by 3,143

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

Cani, P. D., Possemiers, S., Van de Wiele, T., Guiot, Y., Everard, A., Rottier, O., Geurts, L., Naslain, D., Neyrinck, A., Lambert, D. M., et al. (2009) · Gut · doi:10.1136/gut.2008.165886 · Cited by 2,518

The Gut Microbiome and Colonic Motility Disorders: A Practical Framework for the Gastroenterologist

Ma, W., Drew, D. A., & Staller, K. D. (2022) · Current Gastroenterology Reports · doi:10.1007/s11894-022-00847-4 · Cited by 16

Microbiome and metabolome analyses indicate variations in the gut microbiota that disrupt regulation of appetite

Qi, R., Zhang, B., Qiu, X., Liu, X., Bao, S., Wang, J., Wang, Q., Yang, Y., Yang, H., & Liu, Z. (2024) · The FASEB Journal · doi:10.1096/fj.202401360r · Cited by 14

Impact of calcineurin inhibitors on gut microbiota: Focus on tacrolimus with evidence from in vivo and clinical studies

Kunasol, C., Chattipakorn, N., & Chattipakorn, S. C. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177176 · Cited by 14

Gut–lung axis in asthma and obesity: role of the gut microbiome

Tashiro, H., Kuwahara, Y., & Takahashi, K. (2025) · Frontiers in Allergy · doi:10.3389/falgy.2025.1618466 · Cited by 17

Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering

Dietert, R. R. (2021) · Biomedicines · doi:10.3390/biomedicines9111581 · Cited by 15

Microbiome and Diet in Colon Cancer Development and Treatment

Kato, I., & Sun, J. (2023) · The Cancer Journal · doi:10.1097/ppo.0000000000000649 · Cited by 14

Engineering the fish gut microbiome: could it serve as future-proof strategy for sustainable aquaculture?

Ma, A., Sarasan, M., Kachiprath, B., Sukumaran, V., Singh, I. S. B., & Puthumana, J. (2025) · Blue Biotechnology · doi:10.1186/s44315-025-00026-w · Cited by 14

Microbiome and metabolome association network analysis identifies Clostridium_sensu_stricto_1 as a stronger keystone genus candidate than Bifidobacterium in the gut of common marmosets

Hernandez, J. B., Hayer, S. S., Alvarez, S., Fischer, A., Hassenstab, H. R., Cooper, K., Alsafwani, Z. W., Benson, A. K., Haute, M. J. S. V., Izard, J., et al. (2025) · mSystems · doi:10.1128/msystems.00214-25 · Cited by 14

Microbial ecology, functional implications, and associated factors influencing poultry intestinal health

Aminullah, N., Langar, H., Mahaq, O., Azizi, M. N., & Zahir, A. (2026) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2026.111065 · Cited by 14

The 5-HT-related gut-brain axis in obesity

Jiang, C., Zhan, Q., & Zeng, C. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.123171 · Cited by 13

Crosstalk between gut microbiota and renal ischemia/reperfusion injury

Huang, P., Cao, J., Chen, J., Luo, Y., Gong, X., Wu, C., & Wang, Y. H. D. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1015825 · Cited by 13

Amelioration impact of gut-brain communication on obesity control by regulating gut microbiota composition through the ingestion of animal-plant-derived peptides and dietary fiber: can food reward effect as a hidden regulator?

Jia, W., Peng, J., Zhang, Y., Zhu, J., Qiang, X., Zhang, R., & Shi, L. S. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2241078 · Cited by 14

A holistic exploration of the psychosocial, environmental, neurobiological, and individual factors influencing children’s food choices: a narrative review

Albardan, L., & Platat, C. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1645293 · Cited by 22

The gut microbiome from middle-aged women with depression modulates depressive-like behaviors and plasma fatty acid metabolism in female middle-aged mice

Yu, H., Yang, W., Chen, Y.-H., Guo, L., Li, R., Xue, F., Tan, Q.-R., & Peng, Z. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.03.023 · Cited by 12

A menu for microbes: unraveling appetite regulation and weight dynamics through the microbiota-brain connection across the lifespan

Ribeiro, G., Schellekens, H., Cuesta‐Marti, C., Maneschy, I. R., Ismael, S., Cuevas‐Sierra, A., Martínez, J. A., Silvestre, M. P., Marques, C., Moreira-Rosário, A., et al. (2025) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00227.2024 · Cited by 13

Diets Supplemented with Probiotics Improve the Performance of Broilers Exposed to Heat Stress from 15 Days of Age

Ribeiro, J. C. D. D., Drumond, M. M., Mancha-Agresti, P. D. C., Guimaraes, J. P., Ferreira, D. D. C., Martins, M. I. A., Murata, P. M. D. M., de Carvalho, A. C., Pereira, R. T., Ribeiro, V., et al. (2022) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-022-09989-3 · Cited by 12

The contribution of cell wall integrity to gastric emptying and in vitro starch digestibility and fermentation performance of highland barley foods

Chun, L., Zhao, Z., Huang, G., Liu, J., Ye, F., Chen, J., Ming, J., Zhao, G., & Lei, L. (2023) · Food Research International · doi:10.1016/j.foodres.2023.112912 · Cited by 12

A review of anorexia induced by T-2 toxin

Huang, T.-Y., Song, W., Wang, Y.-S., Liu, Y., Chen, F., Chen, Y.-H., Jiang, Y., Zhang, C., & Yang, X. (2023) · Food and Chemical Toxicology · doi:10.1016/j.fct.2023.113982 · Cited by 12

Exercise reshapes gut microbiota to ameliorate core symptoms in PCOS: molecular mechanisms and therapeutic implications

Li, Q., Chen, L., & Wang, R. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1652731 · Cited by 14

Neutrophils in the Focus: Impact on Neuroimmune Dynamics and the Gut–Brain Axis

Kršek, A., & Batičić, L. (2024) · Gastrointestinal Disorders · doi:10.3390/gidisord6030039 · Cited by 13

The role of nutrient sensing dysregulation in anorexia of ageing: The little we know and the much we don't

Dagbasi, A., Fuller, A., Hanyaloglu, A. C., Carroll, B., McLaughlin, J. T., Frost, G. S., & Holliday, A. (2024) · Appetite · doi:10.1016/j.appet.2024.107718 · Cited by 11

Personalized modeling of gut microbiome metabolism throughout the first year of life

Shaaban, R., Busi, S. B., Wilmes, P., Guéant, J., & Heinken, A. (2024) · Communications Medicine · doi:10.1038/s43856-024-00715-4 · Cited by 11

Alleviation of Adipose Tissue Inflammation and Obesity Suppression by a Probiotic Strain That Induces GLP-1 Secretion

Kim, A. R., Jeon, S.-G., Park, S., Hong, H., Kim, B. K., Kim, H., Hong, C., & Yang, B. (2025) · Microorganisms · doi:10.3390/microorganisms13061211 · Cited by 12

Microbial Endocrinology: Host metabolism and appetite hormones interaction with gut microbiome

Ashraf, A., & Hassan, M. I. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112281 · Cited by 13

Precision nutrition for obesity management: A gut microbiota–centered weight-loss approach

Carvalho, L. M., da Mota, J. C. N. L., Ribeiro, A., Carvalho, B. G., Martínez, J. A., & Nicoletti, C. F. (2025) · Nutrition · doi:10.1016/j.nut.2025.112892 · Cited by 10

Baicalin promotes appetite by regulating gut microbiome and immunity?

Zhang, S., Lv, H., Zhong, R., Tang, S., Han, H. L., Cai, X., Chen, L., & Zhang, H. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105557 · Cited by 10

Cross-talk between the infant/maternal gut microbiota and the endocrine system: a promising topic of research

Turroni, F., Rizzo, S. M., Ventura, M., & Bernasconi, S. (2022) · Microbiome Research Reports · doi:10.20517/mrr.2021.14 · Cited by 12

Novel ketamine and zinc treatment for anorexia nervosa and the potential beneficial interactions with the gut microbiome

Elwyn, R., Mitchell, J., Kohn, M. R., Driver, C., Hay, P., Lagopoulos, J., & Hermens, D. F. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105122 · Cited by 10

Role of Food habit and Enteric microbes in the development of colon cancer

Obayomi, O. V., Olaniran, A. F., & Owa, S. O. (2024) · International Conference on Science, Engineering and Business for Driving Sustainable Development Goals (SEB4SDG) · doi:10.1109/seb4sdg60871.2024.10629949 · Cited by 10

Microbiota-gut-brain axis in binge-eating disorder: Towards microbiome-based therapies

Schneider, E., Leigh, S., Lynch, C. M. K., Hilbert, A., Clarke, G. A., Higgs, S., & Cryan, J. F. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104088 · Cited by 10

Gut Microbiota Regulates Food Intake in a Rodent Model of Intermittent Limited Access to Palatable Food

Demangeat, T., Loison, L., Huré, M., do Rego, J. L., Déchelotte, P., Achamrah, N., Coëffier, M., & Ribet, D. (2024) · International Journal of Eating Disorders · doi:10.1002/eat.24339 · Cited by 9

Host associated probiotics Lactobacillus reuteri and Enterococcus faecium Mitigate multidrug resistant Salmonella enterica in broiler chicks

Siddique, A., Ali, R., Andleeb, S., Akbar, S., Hafeez, Z., Imran, M., Syoc, E. P. V., Yue, M., Ganda, E., & Rahman, A. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107859 · Cited by 9

Natural plant polysaccharides drive multidimensional metabolic homeostasis via the “gut microbiota–metabolite–host” axis

Zhang, L., Chen, X., Li, J., Hou, Q., Song, J., Fu, X., Liu, Y., Jin, B., Feng, Y., Zhang, W., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147728 · Cited by 9

The Effects of Tangning Ziyabitusi on Gut Microbiota and T lymphocyte Subsets in Impaired Glucose Regulation Rats

Zhao, B., Nuli, R., Jiao, Y., Zhang, B., Wang, L., & Guan, Y. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2709278 · Cited by 9

Different Approaches to Ergogenic, Pre-, and Probiotic Supplementation in Sports with Different Metabolism Characteristics: A Mini Review

Wiącek, J., & Karolkiewicz, J. (2023) · Nutrients · doi:10.3390/nu15061541 · Cited by 9

Effect of florfenicol administered through feed on Atlantic salmon (Salmo salar) gut and its microbiome

Monticelli, G., Bisesi, J. H., Magnuson, J. T., Schlenk, D., Zarza, C., Peggs, D., & Pampanin, D. M. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.740310 · Cited by 8

Microbiome, Potential Therapeutic Agents: New Players of Obesity Treatment

Ali, M., Iqbal, N., Rakib, M. A., Lee, K., Lee, M., & Kim, Y. (2025) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2501.01024 · Cited by 10

Current Data on the Role of Amino Acids in the Management of Obesity in Children and Adolescents

Zamosteanu, D., Filip, N., Trandafir, L. M., Țarcă, E., Perțea, M., Bordeianu, G., Bernic, J., Heredea, A.-M., & Cojocaru, E. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157129 · Cited by 10

Physical activity and diet associations with the gut microbiota in the Coronary Artery Risk Development in Young Adults (CARDIA) study

Memili, A., Lulla, A., Liu, H., Shikany, J. M., Jacobs, D. R., Langsetmo, L., North, K. E., Jones, C. D., Launer, L. J., & Meyer, K. A. (2022) · Journal of Nutrition · doi:10.1016/j.tjnut.2022.12.019 · Cited by 8

Viewing Bacterial Colonization through the Lens of Systems Biology

Barron, M. R., & Young, V. B. (2022) · mSystems · doi:10.1128/msystems.01383-21 · Cited by 9

The role of the hypothalamus-gut microbiota in the pathogenesis of periparturient fatty liver disease in dairy cows

Wang, H., Liu, Q., Abouelfetouh, M. M., Li, H., Zhu, H., Zhu, C., Kiani, F. A., & Ding, Y. (2024) · The Veterinary Journal · doi:10.1016/j.tvjl.2024.106290 · Cited by 8

Bacillus paralicheniformis-mediated gut microbiota promotes M2 macrophage polarization by inhibiting P38 MAPK signaling to alleviate necrotizing enterocolitis and apoptosis in mice

Yang, S., Pan, H., Wang, T., Zhou, X., Fan, L., Xiao, H., Zhou, Z., Xiao, Y., & Shi, D. (2025) · Microbiological Research · doi:10.1016/j.micres.2025.128136 · Cited by 7

Plant-based dietary indices association with appetite, appetite regulating peptides and gut microbiota in healthy women: a cross-sectional study

Barkhidarian, B., Soveid, N., Samadi, M., Lesani, A., Aghakhani, A., Yekaninejad, M. S., Saedisomeolia, A., Karbasian, M., Siadat, S. D., & Mirzaei, K. (2025) · European Journal of Nutrition · doi:10.1007/s00394-025-03671-4 · Cited by 7

Dietary strategies for appetite regulation: satiety and obesity management

Xia, P., Li, B., Yu, Y., Yu, W., Youssef, M., Hou, T., & Li, J. (2025) · Food & Function · doi:10.1039/d5fo01349f · Cited by 7

AnimalMetaOmics: a multi-omics data resources for exploring animal microbial genomes and microbiomes

Hu, R., Li, F., Chen, Y., Liu, C., Li, J., Ma, Z., Wang, Y., Cui, C., Luo, C., Zhou, P., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad931 · Cited by 10

In vitro fermentation characteristics of different types of fiber‐rich ingredients by pig fecal inoculum

Luo, C., Duan, J., Zhong, R., Liu, L., Gao, Q., Liu, X., Chen, L., & Zhang, H. (2024) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13355 · Cited by 7

Biopsychosocial pathways model of early childhood appetite self-regulation: Temperament as a key to modulation of interactions among systems

Ju, S., McBride, B. A., Oleschuk, M., & Bost, K. K. (2024) · Social Science & Medicine · doi:10.1016/j.socscimed.2024.117338 · Cited by 7

Effects of γ-Irradiated Date (Phoenix dactylifera) Fruit on Growth, Immunological and Antioxidant Parameters of Goldfish (Carassius auratus)

Heidarieh, M., Gholamhosseini, A., Sheikhzadeh, N., & Esteban, M. Á. (2023) · Fishes · doi:10.3390/fishes8050251 · Cited by 7

Systemic Chronic Inflammation: Integrative Strategies for Health Improvement and Prevention of Inflammatory Receptor Overexpression

Puga-Olguín, A., Hernández, M., Fernández-Demeneghi, R., López-Miranda, C. I., & Flores-Aguilar, L. Á. (2025) · Receptors · doi:10.3390/receptors4010005 · Cited by 7

Role of plant-derived protein hydrolysates and peptides in appetite regulation

Li, W., Liu, M., Li, Y., Zhou, J., Zhu, S., Liu, L., Yang, H., & Wang, Z. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.104976 · Cited by 6

The Impact of Environmental Factors on the Secretion of Gastrointestinal Hormones

Smarkusz-Zarzecka, J., Ostrowska, L., & Radziszewska, M. (2025) · Nutrients · doi:10.3390/nu17152544 · Cited by 6

Dysregulation of the Gut-Adipose Tissue-Liver Axis: a Possible Mechanism Behind the Relationship Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes

Longo, S., Rinaldi, T. G., Fernández‐Real, J. M., & Federici, M. (2026) · Current Diabetes Reports · doi:10.1007/s11892-026-01623-8 · Cited by 7

The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis

Qi, R., Wang, J., Sun, J., Qiu, X., Liu, X., Wang, Q., Yang, F., Ge, L., & Liu, Z. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.970470 · Cited by 8

Metagenomics of microbiota following probiotic supplementation in rats subjected to intestinal anastomosis

de Castilho, T. J. C., Almeida, G. H. D. R., Mello, E. V. D. S. L., & Campos, A. C. L. (2023) · Surgery Open Science · doi:10.1016/j.sopen.2023.06.007 · Cited by 6

Human Amniotic Membrane-Derived Mesenchymal Stem Cells Prevent Acute Graft-Versus-Host Disease in an Intestinal Microbiome-Dependent Manner

Bu, X., Gao, Y., Pan, W., Liu, L., Wang, J., Yin, Z., & Ping, B. (2023) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2023.11.005 · Cited by 6

The Effect of Probiotics and Prebiotics on Feed Intake in Cultured Fish

Guerreiro, I., Oliva‐Teles, A., & Enes, P. (2024) · Reviews in Aquaculture · doi:10.1111/raq.12982 · Cited by 6

Theabrownin, gut microbiota, and obesity: Effects and mechanisms

Hu, J., Li, Y., & Zhang, T. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105381 · Cited by 8

Multi-omics analysis explore the mechanism of deoxynivalenol inhibiting rabbit appetite through microbial-gut-brain axis

Yuan, X., Chen, W., Li, R., Guo, H., & Wang, C. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.117849 · Cited by 6

Enhancing small peptide content and improving the microbial community and metabolites in corn gluten meal with solid-state fermentation using keratinase-producing Bacillus strains

Chi, Z., Ye, F., Wang, J., Lv, G., Fang, X., Teng, T., & Shi, B. (2025) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2025.111320 · Cited by 6

Standardized Complex Gut Microbiomes Influence Fetal Growth, Food Intake, and Adult Body Weight in Outbred Mice

Cheatham, C. N., Gustafson, K. L., McAdams, Z. L., Turner, G., Dorfmeyer, R. A., & Ericsson, A. C. (2023) · Microorganisms · doi:10.3390/microorganisms11020484 · Cited by 5

Feeding with resistant maltodextrin suppresses excessive calorie intake in a high-fat diet, mediated by changes in mouse gut microbiota composition, appetite-related gut hormone secretion, and neuropeptide transcriptional levels

Ito, K., Haraguchi, A., Sato, S., Sekiguchi, M., Sasaki, H., Ryan, C., Lyu, Y., & Shibata, S. (2023) · Frontiers in Microbiomes · doi:10.3389/frmbi.2023.1149808 · Cited by 6

Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress

Lei, L., Ji, M., Yang, J., Chen, S., Gu, H., & Yang, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.819289 · Cited by 6

Long-term leucine supplementation increases body weight in goats by controlling appetite and muscle protein synthesis under protein-restricted conditions

Lv, X., Jiang, A., Hua, J., Liu, Z., Yan, Q., Tang, S., Kang, J., Tan, Z., Wu, J., & Zhou, C. (2024) · Animal nutrition · doi:10.1016/j.aninu.2024.09.005 · Cited by 6

Probing the potential microbiota-mediated effects of sodium dehydroacetate on hyperphagia and inflammation in mice

Mo, Q., Shen, F., Ruan, S., Zhang, J., Zhao, M., Feng, F., & Liu, T. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.105879 · Cited by 5

Impact of Diquat on the Intestinal Health and the Composition and Function of the Gut Microbiome

He, J., Tang, Q., Liu, Y., Wang, L., & Chai, Y. (2025) · Antioxidants · doi:10.3390/antiox14060721 · Cited by 6

Association Between Sleep Disturbance and Behavioral Feeding Problems in Children and Adolescents with Autism Spectrum Disorder

Fuentes-Albero, M., Mafla-España, M. A., Martı́nez-Raga, J., & Cauli, O. (2025) · Diseases · doi:10.3390/diseases13090280 · Cited by 5

Tryptophan metabolism in inter-organ communication and its potential applications for disease prevention and control

Tang, X., Wu, J., Hu, Z., Tang, M., Chen, F., Yao, Y., Chen, G., Xiong, X., Zhou, B., Gao, Y., et al. (2025) · The Innovation Life · doi:10.59717/j.xinn-life.2026.100177 · Cited by 5

Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice

Cuesta‐Marti, C., Ponce‐España, E., Uhlig, F., Stoltenborg, I., Wasiewska, L. A., Kareem, L., Hedayatpour, D., Olavarría‐Ramírez, L., Rosell‐Cardona, C., Bastiaanssen, T. F. S., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-68968-2 · Cited by 5

Bacteria and phage consortia modulate cecal SCFA production and host metabolism to enhance feed efficiency in ducks

Wang, X., Tian, S., Zhang, Y., Yang, L., Hu, D., Wang, Z., Yang, X., Li, S., Wei, J., Zhou, W., et al. (2026) · Microbiome · doi:10.1186/s40168-026-02368-y · Cited by 5

Gut microbiota and metabolic modulation by supplementation of polysaccharide-producing Bacillus licheniformis from Tibetan Yaks: A comprehensive multi-omics analysis

Zeng, Z., Quan, C., Zhou, S., Gong, S., Iqbal, M., Kulyar, M. F., Nawaz, S., Li, K., & Li, J. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127808 · Cited by 5

Dietary Lactobacillus delbrueckii Affects Ileal Bacterial Composition and Circadian Rhythms in Pigs

Luo, W., Yin, Z., Zhang, M., Huang, X., & Yin, J. (2024) · Animals · doi:10.3390/ani14030412 · Cited by 6

Does Microbiome Matter in Chronic Intestinal Failure Due to Type 1 Short Bowel Syndrome in Adults?

Ossola, M., Ferrocino, I., Franciosa, I., Aimasso, U., Cravero, L., Bonciolini, A., Cardenia, V., Merlo, F. D., Anrò, M., Chiarotto, A., et al. (2024) · Nutrients · doi:10.3390/nu16142282 · Cited by 5

Can longer lifespan be associated with gut microbiota involvement in lipid metabolism?

Šardzíková, S., Gajewska, M. E., Gałka, N., Štefánek, M., Baláž, A., Garaiová, M., Holič, R., Świderek, W. P., & Šoltýs, K. (2024) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiae135 · Cited by 5

Bioactive compounds regulate appetite through the melanocortin system: a review

Niu, Y., Yu, W., Kou, X., Wu, S., Liu, M., Chen, C., Ji, J., Shao, Y., & Xue, Z. (2024) · Food & Function · doi:10.1039/d4fo04024d · Cited by 5

Intestinal Ecology Changes in Diarrheic Père David’s Deer Revealed by Gut Microbiota and Fecal Metabolites Analysis

Zhen, J., Yuan, X., Tao, L., Zhang, H., Ren, Y., Xie, S., Wang, L., Shen, H., & Chen, Y. (2022) · Animals · doi:10.3390/ani12233366 · Cited by 5

Cancer cachexia – adopting a systems wide approach

Sayers, J., Skipworth, R. J. E., & Laird, B. J. A. (2023) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000951 · Cited by 5

New dawn of ginsenosides: regulating gut microbiota to treat metabolic syndrome

Bai, X., Fu, R., Deng, J., Yang, H., Zhu, C., & Fan, D. (2024) · Phytochemistry Reviews · doi:10.1007/s11101-024-09920-4 · Cited by 5

Microbial–Metabolomic Exploration of Tea Polyphenols in the Regulation of Serum Indicators, Liver Metabolism, Rumen Microorganisms, and Metabolism in Hu Sheep

Wang, H., Zhan, J., Zhao, S., Jiang, H., Jia, H., Yue, P., Zhong, X., & Huo, J. (2024) · Animals · doi:10.3390/ani14182661 · Cited by 5

Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery

Ahmad, M. A., Venema, K., Moubareck, C. A., Wazz, G., Mahdy, T., & Karavetian, M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0318699 · Cited by 5

A narrative review on the role of gut microbiome, dietary strategies, and supplements in managing metabolic syndrome

Chopra, S., Dahiya, V., Shankar, E. M., & Saini, A. (2025) · Exploration of Drug Science · doi:10.37349/eds.2025.1008105 · Cited by 6

Enhancing Human Superorganism Ecosystem Resilience by Holistically ‘Managing Our Microbes’

Coleman, M. E., Dietert, R. R., North, D., & Stephenson, M. M. (2021) · Applied Microbiology · doi:10.3390/applmicrobiol1030031 · Cited by 5

Omega-3-Rich Fish-Oil-Influenced Mouse Gut Microbiome Shaped by Intermittent Consumption of Beef

Park, J., Xuan, B., Jeong, Y., Han, G., & Kim, E. B. (2023) · Current Microbiology · doi:10.1007/s00284-023-03223-1 · Cited by 5

Personalized Nutritional Assessment and Intervention for Athletes: A Network Physiology Approach

Prieto, A., Lizarraga, M. A., & Balagué, N. (2025) · Nutrients · doi:10.3390/nu17233657 · Cited by 4

Significance of the Gut-Brain Axis in the Development of Overweight and Obesity

Kuśmierska, M., Kuśmierski, J., Janik, I., Martyka, A., & Ujma, P. (2024) · Journal of Education Health and Sport · doi:10.12775/jehs.2024.70.49434 · Cited by 4

The Response of the Gut Physiological Function and Microbiome of a Wild Freshwater Fish (Megalobrama terminalis) to Alterations in Reproductive Behavior

Liu, Y., Kou, C., Chen, J., Li, Y., & Li, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137425 · Cited by 4

A study on the effects of metacinnabar (β-HgS) on weight and appetite recovery in stressed mice

Qiao, Y., Chen, H., Guo, J., Zhang, X., Liang, X., Wei, L., Wang, Q., Bi, H., & Gao, T. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118663 · Cited by 6

IUPHAR review: Eating disorders, gut microbiota dysbiosis and epigenetic aberrations

Nohesara, S., Abdolmaleky, H. M., Pettinato, G., Pirani, A., Thiagalingam, S., & Zhou, J. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107653 · Cited by 4

Modes of Action of Probiotics

Nguyen, T. L., Thi, H. H. P., Lee, Y., Lee, J., & Kim, D. (2022) · Springer eBooks · doi:10.1007/978-3-030-98621-6_12 · Cited by 4

Gut microbiota intervention strategies using active components from medicinal herbs to evaluate clinical efficacy of type 2 diabetes – A review

Patel, B. K., Patel, K. H., & Moochhala, S. (2023) · Clinical and Translational Discovery · doi:10.1002/ctd2.170 · Cited by 5

Exploring the Unexplored Arena: Butyrate as a Dual Communicator in Gut–Brain Axis

Bhatia, Z., Kumar, S., & Seshadri, S. (2023) · Springer eBooks · doi:10.1007/978-981-99-1463-0_9 · Cited by 4

In vitro assessment of bacterial supernatants on hypothalamic gene expression: implications for appetite regulation

Cuesta‐Marti, C., Valderrama, B., Bastiaanssen, T. F. S., Cryan, J. F., Stanton, C., O’Mahony, S. M., Clarke, G. A., & Schellekens, H. (2025) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00820-9 · Cited by 3

Integrated 16S rDNA and Metabolomics Analysis Unveils Dietary Fiber-Induced Changes in Small Intestinal Microbiota and Metabolites of Pigs

Wang, H., Qi, L., Xiao, Y., Jin, J., Huang, R., Wu, S., & Bao, W. (2025) · Veterinary Sciences · doi:10.3390/vetsci12111034 · Cited by 3

Food-derived bioactive peptides in gut–muscle Axis regulation: Potential and challenges from microbiota homeostasis to muscle metabolism remodeling

Song, H., Xue, S., Zhao, W., & Yu, Z. (2026) · Food Research International · doi:10.1016/j.foodres.2026.119392 · Cited by 3

Aspergillus oryzae Fermentation of Lophatheri Herba Elevates SCFAs and Transforms Flavonoids to Fortify the Gut Barrier via Microbiota Remodeling in Mice

Ma, X., Chen, J., Chen, R., Liang, W., Huang, R., Tang, L., & Qian, L. (2025) · Nutrients · doi:10.3390/nu17182996 · Cited by 4

From eating to obesity: issues of diagnosis and neuroendocrine regulation. A review

Maksim, O. V., & Салухов, В. В. (2022) · Consilium Medicum · doi:10.26442/20751753.2022.4.201543 · Cited by 3

Exploring the elevation dynamics of rumen bacterial communities in Barn feeding cattle from 900 to 3,600 meters by full-length 16S sequencing

Yang, S., Zheng, J., He, S., Yuan, Z., Wang, R., & Wu, D. (2023) · Frontiers in Veterinary Science · doi:10.3389/fvets.2023.1169573 · Cited by 3

Integrated microbiomics and metabolomics analysis reveals the influence of gut microbiota on the growth and metabolism of sea cucumber seedlings

Jia, A., Niu, X., Zhang, M., Liu, X., Cui, T., Liu, C., & Bai, X. (2024) · Journal of Applied Microbiology · doi:10.1093/jambio/lxae006 · Cited by 3

Pore-Forming Protein LIN-24 Enhances Starvation Resilience in Caenorhabditis elegans by Modulating Lipid Metabolism and Mitochondrial Dynamics

Lan, X., Yang, M., Wang, J., Huang, C., Wu, A., Cui, L., Guo, Y., Zeng, L., Guo, X., Zhang, Y., et al. (2025) · Toxins · doi:10.3390/toxins17020072 · Cited by 3

Acute targeted induction of gut-microbial metabolism affects host clock genes and nocturnal feedingPreprint

Greter, G., Moresi, C., Oswald, S., d’Oplinter, A. D. W., Künzli, D., Barazzone, E. C., Lan, J., Slack, E. M. C., & Arnoldini, M. (2024) · eLife · doi:10.7554/elife.100640.1 · Cited by 3

Hunger Games: A Modern Battle Between Stress and Appetite

Smith, W., & Azevedo, E. P. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70006 · Cited by 3

Microbiota-gut-brain axis: Modulator of host metabolism and appetite

van de Wouw, M., Schellekens, H., Dinan, T. G., & Cryan, J. F. (2017) · The Journal of Nutrition · doi:10.3945/jn.116.240481 · Cited by 461

Endocrine Regulation of Appetite: Interactions between Gut Microbiota, Microbial Metabolites, and Appetite-related Hormones

Arvas, S., Özçelik, O., Beyhan, Y. E., & Algül, Ş. (2026) · Hormone and Metabolic Research · doi:10.1055/a-2851-0224

The effects of gut microbiota on appetite regulation and the underlying mechanisms

Yu, M., Yu, B., & Chen, D. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2414796 · Cited by 100

Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

Fetissov, S. O. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.150 · Cited by 403

Microbiome and metabolome analyses indicate variations in the gut microbiota that disrupt regulation of appetite

Qi, R., Zhang, B., Qiu, X., Liu, X., Bao, S., Wang, J., Wang, Q., Yang, Y., Yang, H., & Liu, Z. (2024) · The FASEB Journal · doi:10.1096/fj.202401360r · Cited by 14