Biochemical and functional characterization of three activated macrophage populations

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,976

The chemokine system in diverse forms of macrophage activation and polarization

MANTOVANI, A., SICA, A., SOZZANI, S., ALLAVENA, P., VECCHI, A., & LOCATI, M. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.09.015 · Cited by 6,534

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528

Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation

Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

Stuehr, D. J., & Nathan, C. F. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.169.5.1543 · Cited by 1,744

Induction by Antigen of Intrathymic Apoptosis of CD4 + CD8 + TCR lo Thymocytes in Vivo

MURPHY, K. M. M., Heimberger, A. B., & Loh, D. Y. (1990) · Science · doi:10.1126/science.2125367 · Cited by 1,714

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

Nathan, C., & Shiloh, M. U. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.16.8841 · Cited by 1,469

Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences

Stout, R. D., Jiang, C., Matta, B., Tietzel, I., Watkins, S. K., & Suttles, J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.1.342 · Cited by 968

Alarmins: chemotactic activators of immune responses

Oppenheim, J. J., & Yang, D. (2005) · Current Opinion in Immunology · doi:10.1016/j.coi.2005.06.002 · Cited by 780

Sustained IL-4 priming of macrophages enhances the inflammatory response to TLR7/8 ligand R848

Banete, A., Gee, K., & Basta, S. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.3a0520-293rr · Cited by 19

Chronic alcohol consumption induces cardiac remodeling in mice from Th1 or Th2 background

Liu, W., Li, J., Tian, W., Xu, T., & Zhang, Z. (2011) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2011.08.003 · Cited by 19

Role of antigen presentation in the production of pro-inflammatory cytokines in obese adipose tissue

Majdoubi, A., Kishta, O. A., & Thibodeau, J. (2016) · Cytokine · doi:10.1016/j.cyto.2016.01.023 · Cited by 20

Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2

Holden, J. A., O’brien-simpson, N. M., Lenzo, J. C., Orth, R., Mansell, A. S., & Reynolds, E. C. (2017) · Infection and Immunity · doi:10.1128/iai.00282-17 · Cited by 19

Phenotypic and Functional Outcomes in Macrophages Exposed to an Environmentally Relevant Mixture of Organophosphate Esters in Vitro

Giles, B. H., Kukolj, N., Mann, K. K., & Robaire, B. (2024) · Environmental Health Perspectives · doi:10.1289/ehp13869 · Cited by 18

The effects of a mineral trioxide aggregate‐based sealer on the production of reactive oxygen species, nitrogen species and cytokines by two macrophage subtypes

Braga, J. M., Oliveira, R. R., Martins, R. D. C., & Sobrinho, A. P. R. (2013) · International Endodontic Journal · doi:10.1111/iej.12234 · Cited by 18

The interaction between different types of activated RAW 264.7 cells and macrophage inflammatory protein-1 alpha

He, Z., Zhang, H., Yang, C., Zhou, Y., Zhou, Y. G., Han, G., Xia, L., Ouyang, W., Zhou, F., Zhou, Y., et al. (2011) · Radiation Oncology · doi:10.1186/1748-717x-6-86 · Cited by 18

Leishmania mexicana promastigotes down regulate JNK and p-38 MAPK activation: Role in the inhibition of camptothecin-induced apoptosis of monocyte-derived dendritic cells

Rodríguez-González, J., Wilkins‐Rodríguez, A. A., Argueta, J., Aguirre‐García, M., & Gutiérrez‐Kobeh, L. (2016) · Experimental Parasitology · doi:10.1016/j.exppara.2015.12.005 · Cited by 18

Coupled Immunological and Biomechanical Model of Emphysema Progression

Ceresa, M., Olivares, A. L., Noailly, J., & Ballester, M. Á. G. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00388 · Cited by 20

Mycobacterium tuberculosis: Macrophage Takeover and Modulation of Innate Effector Responses

Bhat, K. H., & Yaseen, I. (2018) · InTech eBooks · doi:10.5772/intechopen.75003 · Cited by 18

Sex-Specific Microglial Activation and SARS-CoV-2 Receptor Expression Induced by Chronic Unpredictable Stress

Yan, L., Jayaram, M., Chithanathan, K., Zharkovsky, A., & Tian, L. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.750373 · Cited by 19

Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure

Zhang, M., Ye, Y., Wang, F., Zhu, J., Zhao, Q., Zheng, Y., Gu, Y., Xie, C., Huang, Z., Tai, Q., et al. (2014) · Journal of Translational Medicine · doi:10.1186/1479-5876-12-60 · Cited by 18

Activation of Murine Macrophages

Mosser, D. M., & Gonçalves, R. (2015) · Current Protocols in Immunology · doi:10.1002/0471142735.im1402s111 · Cited by 18

MFGE8 in exosomes derived from mesenchymal stem cells prevents esophageal stricture after endoscopic submucosal dissection in pigs

Lai, H., Yip, H. C., Gong, Y., Chan, K. F., Leung, K. K. C., Chan, M. S., Xia, X., & Chiu, P. W. Y. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02429-0 · Cited by 17

Macrophages Undergo M1‐to‐M2 Transition in Adipose Tissue Regeneration in a Rat Tissue Engineering Model

Li, Z., Xu, F., Wang, Z., Dai, T., Ma, C., Liu, B., & Liu, Y. (2016) · Artificial Organs · doi:10.1111/aor.12756 · Cited by 17

Insights into endotoxin-mediated lung inflammation and future treatment strategies

Chakraborty, A., Boer, J. C., Selomulya, C., Plebanski, M., & Royce, S. G. (2018) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2018.1523009 · Cited by 17

Intravenous immunoglobulin (IVIg) or IVIg‐treated macrophages reduce DSS‐induced colitis by inducing macrophage IL‐10 production

Kozicky, L. K., Menzies, S. C., Hotte, N., Madsen, K. L., & Sly, L. M. (2019) · European Journal of Immunology · doi:10.1002/eji.201848014 · Cited by 17

Pericytes in Cutaneous Wound Healing

Morikawa, S., Iribar, H., Gutiérrez‐Rivera, A., Ezaki, T., & Izeta, A. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-16908-4_1 · Cited by 17

Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features

Dong, Z. M., Lin, E., Wechsler, M. E., Weller, P. F., Klion, A. D., Bochner, B. S., Delker, D. A., Hazel, M. W., Fairfax, K. C., Khoury, P., et al. (2020) · American Journal Of Pathology · doi:10.1016/j.ajpath.2020.03.005 · Cited by 17

Overcoming Endogenous Constraints on Neuronal Regeneration

Mokarram, N., & Bellamkonda, R. V. (2011) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2010.2103075 · Cited by 17

Acute and Persistent Alterations of Cerebellar Inflammatory Networks and Glial Activation in a Rat Model of Pediatric Mild Traumatic Brain Injury

Fraunberger, E. A., DeJesus, P., Zanier, E. R., Shutt, T. E., & Esser, M. J. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2019.6714 · Cited by 19

The Polarization of M2b Monocytes in Cultures of Burn Patient Peripheral CD14 + Cells Treated with a Selected Human CCL1 Antisense Oligodeoxynucleotide

Ito, I., Bhopale, K. K., Nishiguchi, T., Lee, J. O., Herndon, D. N., Suzuki, S., Sowers, L. C., Suzuki, F., & Kobayashi, M. (2016) · Nucleic Acid Therapeutics · doi:10.1089/nat.2016.0617 · Cited by 17

TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors

Zaal, A., Nota, B., Moore, K., Dieker, M. C., van Ham, S. M., & ten Brinke, A. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.2ma0217-058r · Cited by 16

Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived cells to different stimuli

Miller, L. C., Fleming, D. S., Li, X., Bayles, D. O., Blecha, F., & Sang, Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181256 · Cited by 16

Selective killing of human M1 macrophages by Smac mimetics alone and M2 macrophages by Smac mimetics and caspase inhibition

Ali, H., Caballero, R. E., Dong, S. X. M., Gajnayaka, N., Vranjkovic, A., Ahmed, D., Iqbal, S., Crawley, A. M., Angel, J. B., Cassol, E., et al. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.4a0220-114rr · Cited by 16

Evaluating Macrophages in Immunotoxicity Testing

Barnett, J. B., & Brundage, K. M. (2009) · Methods in molecular biology · doi:10.1007/978-1-60761-401-2_6 · Cited by 16

Support of HUVEC proliferation by pro-angiogenic intermediate CD163 + monocytes/macrophages: A co-culture experiment

Mayer, A., Hiebl, B., Lendlein, A., & Jung, F. (2011) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-2011-1492 · Cited by 16

B-1 cell-mediated modulation of M1 macrophage profile ameliorates microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi

Pereira, A. A., Alvares-Saraiva, A. M., Konno, F. T., Spadacci-Morena, D. D., Pérez, E. C., Mariano, M., & Lallo, M. A. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007674 · Cited by 17

The regulatory peptide pidotimod facilitates M2 macrophage polarization and its function

Hu, S., Fu, X., Fu, A., Du, W., Ji, J., & Li, W. (2014) · Amino Acids · doi:10.1007/s00726-014-1676-4 · Cited by 16

Macrophages of different tissue origin exhibit distinct inflammatory responses to mycobacterial infection

Stevens, M. T., Nagaria, B. D., Britton, W. J., & Saunders, B. M. (2021) · Immunology and Cell Biology · doi:10.1111/imcb.12493 · Cited by 15

Resistance Against Leishmania major Infection Depends on Microbiota-Guided Macrophage Activation

Lopes, M. E., dos Santos, L. M., Sacks, D. L., Vieira, L. Q., & Carneiro, M. B. H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.730437 · Cited by 15

Role of host- and pathogen-associated lipids in directing the immune response in mycobacterial infections, with emphasis onMycobacterium aviumsubsp.paratuberculosis

Thirunavukkarasu, S., de Silva, K., Plain, K. M., & Whittington, R. J. (2014) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2014.932327 · Cited by 15

Immunopathogenesis and therapeutic potential of macrophage influx in diffuse parenchymal lung diseases

Kulshrestha, R., Dhanda, H., Pandey, A., Singh, A. K., & Kumar, R. (2020) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2020.1776117 · Cited by 15

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice

Sheean, R. K., Weston, R. H., Perera, N. D., D’Amico, A., Nutt, S. L., & Turner, B. J. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0254-3 · Cited by 15

Mesenchymal stem cells regulate M1 polarization of peritoneal macrophages through the CARD9‐NF‐κB signaling pathway in severe acute pancreatitis

Wang, J., Tian, J., Wang, L., Yang, Z., & Xu, P. (2022) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1002/jhbp.1205 · Cited by 14

KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage

Ergashev, A., Shi, F., Liu, Z., Pan, Z., Xie, H., Kong, L., Wu, L., Sun, H., Jin, Y., Kong, H., et al. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.11.010 · Cited by 14

Ligation of Macrophage Fcγ Receptors Recapitulates the Gene Expression Pattern of Vulnerable Human Carotid Plaques

Lennartz, M. R., Aggarwal, A., Michaud, T. M., Feustel, P. J., Jones, D., Brosnan, M. J., Keller, R. S., Loegering, D. J., & Kreienberg, P. B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021803 · Cited by 14

Increased expression of the TNF superfamily member LIGHT/TNFSF14 and its receptors (HVEM and LTßR) in patients with systemic sclerosis

Gińdzieńska‐Sieśkiewicz, E., Distler, O., Reszeć, J., Jordan, S., Bielecki, P., Sieśkiewicz, A., Sulik, A., Lukasik, M., Bielecki, M., Kowal, K., et al. (2018) · Rheumatology · doi:10.1093/rheumatology/key348 · Cited by 14

Stress‐related suppression of peripheral cytokines predicts future relapse in alcohol‐dependent individuals with and without subclinical depression

Fox, H. C., Milivojevic, V., MacDougall, A., LaVallee, H., Simpson, C. A., Angarita, G. A., & Sinha, R. (2019) · Addiction Biology · doi:10.1111/adb.12832 · Cited by 15

The role of Toll-like receptor signaling in the macrophage response to implanted materials

McKiel, L. A., Woodhouse, K. A., & Fitzpatrick, L. E. (2019) · MRS Communications · doi:10.1557/mrc.2019.154 · Cited by 15

Host immune cellular reactions in corneal neovascularization

Abdelfattah, N. S., Amgad, M. T., & Zayed, A. A. (2016) · International Journal of Ophthalmology · doi:10.18240/ijo.2016.04.25 · Cited by 14

Host Intracellular Signaling Events and Pro-inflammatory Cytokine Production in African Trypanosomiasis

Kuriakose, S. M., Singh, R. V., & Uzonna, J. E. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00181 · Cited by 14

Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler’s Murine Encephalomyelitis

Hansmann, F., Zhang, N., Herder, V., Leitzen, E., & Baumgärtner, W. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071702 · Cited by 14

Immune Complex–Driven Generation of Human Macrophages with Anti-Inflammatory and Growth-Promoting Activity

Dalby, E., Christensen, S. M., Wang, J., Hamidzadeh, K., Chandrasekaran, P., Hughitt, V. K., Tafuri, W. L., Arantes, R. M. E., Júnior, I. A. R., Herbst, R., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1901382 · Cited by 15

Therapeutic strategies targeting synovial cells to treat osteoarthritis

Li, F., Venkatesan, J. K., Madry, H., & Cucchiarini, M. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118317 · Cited by 13

Induction of Macrophage-Like Immunosuppressive Cells from Mouse ES Cells That Contribute to Prolong Allogeneic Graft Survival

Kudo, H., Wada, H., Sasaki, H., Tsuji, H., Otsuka, R., Baghdadi, M., Kojo, S., Chikaraishi, T., & Seino, K.-I. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111826 · Cited by 13

Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function

Ferrero-Andrés, A., Closa, D., Roselló‐Catafau, J., & Folch‐Puy, E. (2020) · Polymers · doi:10.3390/polym12123044 · Cited by 13

Helminth Antigen Exposure Enhances Early Immune Control of Mycobacterium tuberculosis in Monocytes and Macrophages

Togarsimalemath, S. K., Pushpamithran, G., Schön, T., Stendahl, O. I., & Blomgran, R. (2020) · Journal of Innate Immunity · doi:10.1159/000512279 · Cited by 13

Hypoxia induces inflammatory microenvironment by priming specific macrophage polarization and modifies LSC behaviour via VEGF-HIF1α signalling

Jiang, M., He, G., Wang, J., Guo, X. N., Zhao, Z., & Gao, J. (2021) · Translational Pediatrics · doi:10.21037/tp-21-86 · Cited by 13

The Possible Pathogenic Role of IgG4-Producing Plasmablasts in Stricturing Crohn’s Disease

Bushara, O., Escobar, D., Weinberg, S. E., Sun, L., Liao, J., & Yang, G. (2022) · Pathobiology · doi:10.1159/000521259 · Cited by 14

N-Acetylglucosaminyltransferase V exacerbates murine colitis with macrophage dysfunction and enhances colitic tumorigenesis

Shinzaki, S., Ishii, M., Fujii, H., Iijima, H., Wakamatsu, K., Kawai, S., Shiraishi, E., Hiyama, S., Inoue, T., Hayashi, Y., et al. (2015) · Journal of Gastroenterology · doi:10.1007/s00535-015-1119-3 · Cited by 13

Immortalized Murine Macrophage Cell Line as a Model for Macrophage Polarization into Classically Activated M(IFNγ+LPS) or Alternatively Activated M(IL-4) Macrophages

Achita, A. B. P. (2015) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000318 · Cited by 13

Monocyte/Macrophage: NK Cell Cooperation—Old Tools for New Functions

Wałajtys-Rode, E., & Dzik, J. M. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-54090-0_5 · Cited by 13

The effects of glucose concentrations associated with lipopolysaccharide and interferon-gamma stimulus on mediators’ production of RAW 264.7 cells

Cantuária, A. P. D. C., Figueiredo, T. D. M., Freire, M. S., Lima, S. M. D. F., de Almeida, J. A., Franco, O. L., & Rezende, T. M. B. (2018) · Cytokine · doi:10.1016/j.cyto.2017.11.008 · Cited by 13

Activación alternativa del macrófago: La diversidad en las respuestas de una célula de la inmunidad innata ante la complejidad de los eventos de su ambiente

Correa, M. A. D., & López, M. R. (2007) · Inmunología · doi:10.1016/s0213-9626(07)70077-x · Cited by 13

Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders

Chen, G., & Li, C. (2023) · Current Neurovascular Research · doi:10.2174/0115672026274954230919070115 · Cited by 13

Novel insights into the immune regulatory effects of Megalobrama amblycephala intelectin on the phagocytosis and killing activity of macrophages

Zheng, Y., Liu, Y., Li, H., Wang, X., Zhang, M., Shen, X., Cheng, H., Xu, J., Wang, X., Liu, H., et al. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.06.008 · Cited by 12

The impact of the PCSK-9/VLDL-Receptor axis on inflammatory cell polarization

Barcena, M. L., Estepa, M., Marx, L., Breiter, A., Haritonow, N., & Stawowy, P. (2022) · Cytokine · doi:10.1016/j.cyto.2022.156077 · Cited by 12

Macrophage Control of Phagocytosed Mycobacteria Is Increased by Factors Secreted by Alveolar Epithelial Cells through Nitric Oxide Independent Mechanisms

Petursdottír, D. H., Chuquimia, O. D., Freidl, R., & Fernández, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103411 · Cited by 12

Bacterial Superinfection Following Lung Inflammatory Disorders

Habibzay, M., Weiss, G., & Hussell, T. (2013) · Future Microbiology · doi:10.2217/fmb.12.143 · Cited by 12

Granulocyte/Macrophage Colony-Stimulating Factor-Derived Macrophages Exhibit Distinctive Early Immune Response to Lymphocytic Choriomeningitis Virus Infection

Alothaimeen, T., Seaver, K., Mulder, R., Gee, K., & Basta, S. (2020) · Viral Immunology · doi:10.1089/vim.2019.0178 · Cited by 12

Time-series biological responses toward decellularized bovine tendon graft and autograft for 52 consecutive weeks after rat anterior cruciate ligament reconstruction

Itoh, M., Imasu, H., Takano, K., Umezu, M., Okazaki, K., & Iwasaki, K. (2022) · Scientific Reports · doi:10.1038/s41598-022-10713-y · Cited by 11

Application of silver nanoparticles for improving motor recovery after spinal cord injury via reduction of pro-inflammatory M1 macrophages

Lin, J., Chen, P., Tan, Z., Sun, Y., Tam, W. K., Ao, D., Shen, W., Leung, V., Cheung, K., & To, M. K.-T. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e15689 · Cited by 11

The multivalency game ruling the biology of immunity

Aiassa, L. V., Battaglia, G., & Rizzello, L. (2023) · Biophysics Reviews · doi:10.1063/5.0166165 · Cited by 11

Exosomes Derived From Cerulein-Stimulated Pancreatic Acinar Cells Mediate Peritoneal Macrophage M1 Polarization and Pyroptosis via an miR-24-3p/MARCH3/NLRP3 Axis in Acute Pancreatitis

Su, X., Chen, Y., Zhang, Q.-C., Peng, X., Liu, Y., Wang, L., & Du, Y. (2024) · Pancreas · doi:10.1097/mpa.0000000000002351 · Cited by 11

New insights into therapeutic strategies for targeting hepatic macrophages to alleviate liver fibrosis

Zhang, J., Xie, Z., Zhu, X., Xu, C., Lin, J., Zhao, M., & Cheng, Y. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114864 · Cited by 11

PDMS Micropatterns Coated with PDA and RGD Induce a Regulatory Macrophage-like Phenotype

Pham, H. L., Yang, D. H., Chae, W. R., Jung, J. H., Hoang, T. X., Lee, N. Y., & Kim, J. Y. (2023) · Micromachines · doi:10.3390/mi14030673 · Cited by 11

The Molecular Basis of Antibody Protection Against West Nile Virus

Diamond, M. S., & Mehlhop, E. (2007) · Current topics in microbiology and immunology · doi:10.1007/978-3-540-72146-8_5 · Cited by 11

Effect of CCL2 antisense oligodeoxynucleotides on bacterial translocation and subsequent sepsis in severely burned mice orally infected with Enterococcus faecalis

Shigematsu, K., Kogiso, M., Kobayashi, M., Herndon, D. N., & Suzuki, F. (2011) · European Journal of Immunology · doi:10.1002/eji.201141572 · Cited by 11

Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2

Bandow, K., Hasegawa, H., Tomomura, M., & Tomomura, A. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.01.045 · Cited by 11

Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes

Achmus, L., Ruhnau, J., Grothe, S., von Sarnowski, B., Bröker, B. M., Dressel, A., Schulze, J., & Vogelgesang, A. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.577971 · Cited by 11

Differential TLR7-mediated cytokine expression by R848 in M-CSF- versus GM-CSF-derived macrophages after LCMV infection

Alothaimeen, T., Trus, E., Basta, S., & Gee, K. (2020) · Journal of General Virology · doi:10.1099/jgv.0.001541 · Cited by 11

Surfactant protein-D modulation of pulmonary macrophage phenotype is controlled byS-nitrosylation

Guo, C., Atochina‐Vasserman, E. N., Абрамова, Е. В., Smith, L. C., Beers, M. F., & Gow, A. J. (2019) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00506.2018 · Cited by 11

Advances in biomimetic hydrogel for articular cartilage defect repair: Enabling immunomodulation and chondrogenesis

Zheng, C., Wu, Y., Luan, F., Wei, C., Zhang, C., Liu, W., Wang, W., & Chen, J. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114760 · Cited by 10

p16High immune cells control disease tolerance as a defense and health span-extending strategy

Triana-Martínez, F., Pierantoni, A., Graça, D., Bergo, V., Emelyanov, A., Gallerand, A., Grosse, L., Grigorash, B. B., Polyzou, A., Castiglione, A., et al. (2026) · Immunity · doi:10.1016/j.immuni.2026.02.013 · Cited by 10

High-Density-Immune-Complex Regulatory Macrophages Promote Recovery of Experimental Colitis in Mice

Lopes, T. C. M., Almeida, G. G., de Souza, I. A., Borges, D. C., de Lima, W. G., Prazeres, P. H. D. M., Birbrair, A., Arantes, R. M. E., Mosser, D. M., & Gonçalves, R. (2021) · Inflammation · doi:10.1007/s10753-020-01403-w · Cited by 10

Progesterone alters the activation and typing of the microglia in the optic nerve crush model

Yang, P., Chen, L., Shi, Y., Zhou, F., Tian, H., Li, J., & Gao, L. (2021) · Experimental Eye Research · doi:10.1016/j.exer.2021.108805 · Cited by 10

Innate immune cellular therapeutics in transplantation

Ott, L. C., & Cuenca, A. G. (2023) · Frontiers in Transplantation · doi:10.3389/frtra.2023.1067512 · Cited by 10

Isolation and Culture of Bone Marrow-Derived Macrophages from Mice

Gonçalves, R., Murta, G. K. T., de Souza, I. A., & Mosser, D. M. (2023) · Journal of Visualized Experiments · doi:10.3791/64566 · Cited by 12

Extracellular vesicles of Trypanosoma cruzi and immune complexes they form with sialylated and non-sialylated IgGs increase small peritoneal macrophage subpopulation and elicit different cytokines profiles

Cornet-Gómez, A., Moreira, L. R., Gómez-Samblás, M., & Osuna, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1215913 · Cited by 10

Regulatory macrophages in solid organ xenotransplantation

Hoang, T. X., & Kim, J. Y. (2023) · Korean Journal of Transplantation · doi:10.4285/kjt.23.0055 · Cited by 10

Natural Helicobacter infection modulates mouse intestinal muscularis macrophage responses

Hoffman, S. M., & Fleming, S. D. (2010) · Cell Biochemistry and Function · doi:10.1002/cbf.1709 · Cited by 10

Macrophage and Multinucleated Giant Cell Classification

Trout, K. L., Jessop, F., & Migliaccio, C. T. (2015) · Current topics in environmental health and preventive medicine · doi:10.1007/978-4-431-55732-6_1 · Cited by 12

Platelet-rich plasma-induced feedback inhibition of activin A/follistatin signaling: A mechanism for tumor-low risk skin rejuvenation in irradiated rats

Omar, N. N., Rashed, R. R., El‐Hazek, R. M., El‐Sabbagh, W. A., Rashed, E. R., & El‐Ghazaly, M. A. (2018) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2018.01.024 · Cited by 10

Hepatic F4/80+CD11b+CD68– cells influence the antibacterial response in irradiated mice with sepsis by Enterococcus faecalis

Okamoto, N., Ohama, H., Matsui, M., Fukunishi, S., Higuchi, K., & Asai, A. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.4a0820-550rr · Cited by 10

PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function

Jiang, M., Xue, Y., Li, J., Rao, K., Yan, S., Li, H., Chen, X., Li, R., & Liu, D. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s306846 · Cited by 10

Tyro3 receptor tyrosine kinases in the heterogeneity of apoptotic cell uptake

Jeffrey, L. C. (2009) · Frontiers in bioscience · doi:10.2741/3401 · Cited by 10

Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages

de Barros, M. S., Lara, P. G., Fonseca, M. T., Moretti, E. H., Filgueiras, L. R., Martins, J. O., Capurro, M. L., Steiner, A. A., & Sá‐Nunes, A. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3487-7 · Cited by 10

Docosahexaenoic acid impacts macrophage phenotype subsets and phagolysosomal membrane permeability with particle exposure

Fletcher, P., Hamilton, R. F., Rhoderick, J. F., Pestka, J. J., & Holian, A. (2020) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2020.1842826 · Cited by 10

Alleviating osteoarthritis-induced damage through extracellular vesicles derived from inflammatory chondrocytes

Xu, Y., Ye, Z., Wang, Y., Ma, Y., Chen, X., Wang, S., Zhang, B., & Xia, C. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113829 · Cited by 9

M2 ‐Like Macrophages Exhibit Sialic Acid‐Enhanced Efferocytosis via the Siglec CD22

Kukan, E. N., Fabiano, G. L., Glendenning, L. M., Zhou, J. Y., Telfer, K., Paulson, J. C., & Cobb, B. A. (2025) · The FASEB Journal · doi:10.1096/fj.202500146rr · Cited by 9

Intranasal IL-4 Administration Alleviates Functional Deficits of Periventricular Leukomalacia in Neonatal Mice

Yu, L.-C., Miao, J., Li, W., Chen, N., & Chen, Q.-X. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00930 · Cited by 9

SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis

Gu, M., Pan, B., Chen, W., Xu, H., Wu, X., Hu, X., Zheng, L., Ye, Y., Meng, Q., Xian, G., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.794429 · Cited by 9

BACTERIOPHAGE M13 MODULATES THE SEPSIS-RELATED INFLAMMATORY RESPONSES AND ORGAN DAMAGE IN A CLP MODEL

Rahimi, A., Soudi, S., Vakilian, S., Jamshidi‐Adegani, F., Sadeghizadeh, M., & Al‐Hashmi, S. (2022) · Shock · doi:10.1097/shk.0000000000002076 · Cited by 9

Modular Analysis of Bioinformatics Demonstrates a Critical Role for NF-κB in Macrophage Activation

Zhang, Y., Wang, Y., Lu, M., Qiao, X., Sun, B., Zhang, W., & Xue, D. (2014) · Inflammation · doi:10.1007/s10753-014-9851-z · Cited by 9

Derivation of Macrophages from Mouse Bone Marrow

Davis, B. K. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9167-9_3 · Cited by 9

M13 phage coated surface elicits an anti-inflammatory response in BALB/c and C57BL/6 peritoneal macrophages

Safari, Z., Sadeghizadeh, M., Asgaritarghi, G., Bardania, H., Sadeghizadeh, D., & Soudi, S. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.108654 · Cited by 12

A decrease in the innate immune response to infection in the presence of root canal sealers

Mendes, S. T. D. O., de Brito, L. C. N., Rezende, T. M. B., Reis, R. D. O., Cardoso, F. P., Vieira, L. Q., & Sobrinho, A. P. R. (2009) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2009.09.019 · Cited by 9

Diet and leukocytes

Smith, C. W. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1257 · Cited by 9

Mechanisms Underlying Tumor-Associated Macrophages (TAMs)-Facilitated Metastasis

Aleebrahim‐Dehkordi, E., Deravi, N., Fallahi, M. S., & Rezaei, N. (2023) · Springer eBooks · doi:10.1007/978-3-030-80962-1_66-1 · Cited by 8

Characterization of the Type II Activated Macrophage and the Regulation of Heparin Binding EGF-like Growth Factor

Edwards, J. P. (2008) · University Libraries (University of Maryland)

Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation

Verreck, F. A. W., de Boer, T., Langenberg, D. M. L., van der Zanden, L., & Ottenhoff, T. H. M. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0105015 · Cited by 383

Lymph node macrophage heterogeneity: the phenotypic and functional characterization of two distinct populations of macrophages from rat lymph node

Chao, D., & MacPherson, G. G. (1989) · European Journal of Immunology · doi:10.1002/eji.1830190719 · Cited by 14

Alternatively activated macrophages actively inhibit proliferation of peripheral blood lymphocytes and CD4+ T cells in vitro

Schebesch, C., Kodelja, V., Müller, C., Hakij, N., Bisson, S., Orfanos, C. E., & Goerdt, S. (1997) · Immunology · doi:10.1046/j.1365-2567.1997.00371.x · Cited by 121

Comparative analysis of phenotypes of classically (M1) and alternatively (M2) activated macrophages

Xiong, S. (2008) · Cited by 1