The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene
Abstract
Transgenic mice expressing an inducible suicide gene, which allows systemic and reversible elimination of macrophages, were developed. A macrophage-specific c-fms promoter was used to express enhanced green fluorescent protein and a drug-inducible suicide gene that leads to Fas-mediated apoptosis in resting and cycling cells of the macrophage lineage. Transgenic mice were fertile, of normal weight, and showed no abnormal phenotype before drug exposure. The transgene was expressed constitutively in macrophages and dendritic cells (DC) but not significantly in T cells or B cells. Induction of the suicide gene led to depletion of 70–95% of macrophages and DC in nearly all tissues examined. Depletion reduced the ability to clear bacteria from the blood and led to increased bacterial growth in the liver. Depleted mice displayed several abnormalities, including splenomegaly, lymphadenopathy, thymic atrophy, extramedullary hematopoiesis, and development of peritoneal adhesions. This new, transgenic line will be useful in investigating the role of macrophages and DC.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“BM MΦs play a critical role in bone repair: ablation of macrophages is associated with decreased bone deposition within the fracture callus and higher rates of non-union [13, 14, 24].”
From Osteoimmunology of Fracture Healing. (2024) · cites this paper as [24]
In the citing paper
“Furthermore, an EGFP transgene included in this model enables the in situ fluorescent monitoring of macrophage cells42.”
From Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates (2015) · cites this paper as [42]
In the citing paper
“In this model, a macrophage Fas-induced apoptosis transgene enable inducible/reversible apoptosis of macrophages using the mouse colony stimulating factor 1 receptor promoter (Csf1r) to drive expression of a mutant human FK506 binding protein 1A, 12kDa42.”
From Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates (2015) · cites this paper as [42]
Citations
Cites
Death Receptors: Signaling and Modulation
Ashkenazi, A., & Dixit, V. M. (1998) · Science · doi:10.1126/science.281.5381.1305 · Cited by 5,866
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
Scott, E. W., Simon, M. C., Anastasi, J., & Singh, H. (1994) · Science · doi:10.1126/science.8079170 · Cited by 1,532
Dai, X.-M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V., & Stanley, E. R. (2002) · Blood · doi:10.1182/blood.v99.1.111 · Cited by 1,184
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., et al. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00949.x · Cited by 1,130
IL-6 switches the differentiation of monocytes from dendritic cells to macrophages
Chomarat, P., Banchereau, J., Davoust, J. M., & Palucka, K. (2000) · Nature Immunology · doi:10.1038/82763 · Cited by 906
Peritoneal Adhesions: Etiology, Pathophysiology, and Clinical Significance
Liakakos, T., Thomakos, N., Fine, P. M., Dervenis, C., & Young, R. L. (2001) · Digestive Surgery · doi:10.1159/000050149 · Cited by 687
Sasmono, R. T., Oceandy, D., Pollard, J. W., Tong, W., Pavli, P., Wainwright, B. J., Ostrowski, M. C., Himes, S. R., & Hume, D. A. (2003) · Blood · doi:10.1182/blood-2002-02-0569 · Cited by 662
Cecchini, M. G., Dominguez, M. G., Mocci, S., Wetterwald, A., Felix, R., Fleisch, H. A., Chisholm, O., Hofstetter, W., Pollard, J. W., & Stanley, E. R. (1994) · Development · doi:10.1242/dev.120.6.1357 · Cited by 557
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
Kamath, A. T., Henri, S., Battye, F. L., Tough, D. F., & Shortman, K. (2002) · Blood · doi:10.1182/blood.v100.5.1734.h81702001734_1734_1741 · Cited by 454
Mesothelial cells: Their structure, function and role in serosal repair
Mutsaers, S. E. (2002) · Respirology · doi:10.1046/j.1440-1843.2002.00404.x · Cited by 436
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–300 of 306
Grégoire, D., & Kmita, M. (2013) · Methods in molecular biology · doi:10.1007/978-1-60327-292-6_25 · Cited by 16
Gao, X., Kady, N., Wang, C., Abdelrahman, S., Gann, P. H., Sverdlov, M. S., Wolfe, A., Brown, N. A., Reneau, J. C., Robida, A. M., et al. (2022) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0336 · Cited by 14
Minimally invasive longitudinal intravital imaging of cellular dynamics in intact long bone
Bhattacharyya, N. D., Kyaw, W., McDonald, M. M., Dhenni, R., Grootveld, A. K., Xiao, Y., Chai, R. C. C., Khoo, W. H., Dansereau, L. C., Sergio, C. M., et al. (2023) · Nature Protocols · doi:10.1038/s41596-023-00894-9 · Cited by 13
Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis
Saini, Y., Lewis, B. W., Yu, D., Dang, H., Livraghi-Butrico, A., Piero, F. D., O’Neal, W. K., & Boucher, R. C. (2018) · Physiological Reports · doi:10.14814/phy2.13677 · Cited by 14
CD45 expression discriminates waves of embryonic megakaryocytes in the mouse
Cortegano, I., Serrano, N., Ruíz, C., Rodríguez, M., Prado, C., Alía, M., Hidalgo, A., Cano, E., de Andrés, B., & Gaspar, M.-L. (2018) · Haematologica · doi:10.3324/haematol.2018.192559 · Cited by 14
A survey of neurological decompression illness in commercial breath-hold divers (Ama) of Japan.
Tamaki, H., Kohshi, K., Ishitake, T., & Wong, R. M. S. (2010) · PubMed · Cited by 14
Peripheral macrophages contribute to nociceptor priming in mice with chronic intermittent hypoxia
Chivers, S. B., Andrade, M. A., Hammack, R. J., Shannonhouse, J. L., Gómez, R. S., Zhang, Y., Nguyen, B. T., Shah, P., Kim, Y. S., Toney, G. M., et al. (2024) · Science Signaling · doi:10.1126/scisignal.adn8936 · Cited by 13
Geraghty, T., Ishihara, S., Obeidat, A. M., Adamczyk, N. S., Hunter, R. S., Li, J., Wang, L., Lee, H., Ko, F. C., Malfait, A., et al. (2024) · Arthritis Research & Therapy · doi:10.1186/s13075-024-03457-9 · Cited by 13
Molina-Sánchez, P., Chèvre, R., Rius, C., Fuster, J. J., & Andrés, V. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.04.013 · Cited by 13
Visualization of Immune Responses in the Cornea
Perez, V. L. (2017) · Cornea · doi:10.1097/ico.0000000000001354 · Cited by 13
Electrostatic Accumulation and Release of DNA Using a Micromachined Lance
Aten, Q. T., Jensen, B. D., Burnett, S. H., & Howell, L. L. (2011) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2011.2167658 · Cited by 12
Self-citationInvestigating the role of macrophages in tumor formation using a MaFIA mouse model
Clifford, A., El‐Naggar, A. M., Robison, R. A., & O'Neill, K. L. (2013) · Oncology Reports · doi:10.3892/or.2013.2508 · Cited by 12
Albee, L. D., Shi, B., & Perlman, H. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0506358 · Cited by 12
Lancaster, J. N., & Ehrlich, L. I. R. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6931-9_2 · Cited by 12
Phan, Q. T., Liu, R., Tan, W. H., Imangali, N., Cheong, B., Schartl, M., & Winkler, C. (2020) · JBMR Plus · doi:10.1002/jbm4.10409 · Cited by 11
Xiao, L., Matharoo, J., Chi, J. A., Ma, J., Chen, M., Manley, B. J., Xu, P., Shi, W., Felder, R. A., Sung, S.-S. J., et al. (2023) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2023.01.574 · Cited by 11
Queme, L. F., Dourson, A. J., Hofmann, M. C., Butterfield, A., Paladini, R. D., & Jankowski, M. P. (2022) · eNeuro · doi:10.1523/eneuro.0522-21.2022 · Cited by 11
Konduri, V., Decker, W. K., Halpert, M. M., Gilbert, B. E., & Safdar, A. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit087 · Cited by 11
OsteoMac: A new player on the bone biology scene
Iglesias‐Velázquez, Ó., Tresguerres, F. G. F., Tresguerres, I. F., Berrocal, M. I. L., López‐Pintor, R. M., Baca, L., & Torres, J. (2024) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2024.152244 · Cited by 13
Cancer fitness genes: emerging therapeutic targets for metastasis
Shen, M., & Kang, Y. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.08.007 · Cited by 10
Tian, T., Jin, M. Q., Dubin, K. A., King, S. L., Hoetzenecker, W., Murphy, G. F., Chen, C. A., Kupper, T. S., & Fuhlbrigge, R. C. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1500106 · Cited by 10
Controlling Protein–Protein Interactions Using Chemical Inducers and Disrupters of Dimerization
Clackson, T. (2007) · Chemical biology · doi:10.1002/9783527619375.ch4b · Cited by 10
Nagree, M. S., López-Vásquez, L., & Medin, J. A. (2015) · PubMed · doi:10.4252/wjsc.v7.i11.1233 · Cited by 11
Characterising Pre-pubertal Resistance to Death from Endotoxemia
Joachim, R. B., Suber, F., & Kobzik, L. (2017) · Scientific Reports · doi:10.1038/s41598-017-16743-1 · Cited by 9
Generation of a novel mouse model for the inducible depletion of macrophages in vivo
Gheryani, N. A., Coffelt, S. B., Gartland, A., Rumney, R. M. H., Kiss‐Toth, E., Lewis, C. E., Tozer, G. M., Greaves, D. R., Dear, T. N., & Miller, G. (2012) · genesis · doi:10.1002/dvg.22343 · Cited by 9
Depletion of Microglia from Primary Cellular Cultures
Pont‐Lezica, L., Colasse, S., & Bessis, A. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-520-0_7 · Cited by 9
Apoptosis and Clearance of the Secretory Mammary Epithelium
Jamie, C. B., & Rebecca, S. (2013) · InTech eBooks · doi:10.5772/52160 · Cited by 8
Brum, E. S., Landini, L., Souza Monteiro de Araújo, D., Marini, M., Geppetti, P., Nassini, R., De Logu, F., & Oliveira, S. M. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.01.040 · Cited by 8
Kwok, T., Silva, I., Korpe, S., Dong, H., & Lancaster, J. N. (2025) · iScience · doi:10.1016/j.isci.2025.113538 · Cited by 10
In vivo depletion and genetic targeting of mouse intestinal CX3CR1+ mononuclear phagocytes
Koscsó, B., Gowda, K., & Bogunovic, M. (2015) · Journal of Immunological Methods · doi:10.1016/j.jim.2015.12.009 · Cited by 8
Tian, T., Xue, Y., Song, Z., Jin-Smith, B., Barkin, J., Ottallah, M., Mannan, M., Zhirkova, A. M., Zhou, D., & Pi, L. (2025) · GeroScience · doi:10.1007/s11357-025-01952-8 · Cited by 7
Guo, D., Jurek, R. J., Beaumont, K. A., Sharp, D. M., Tan, S., Mariana, A., Failes, T. W., Grootveld, A. K., Bhattacharyya, N. D., Phan, T. G., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2303978120 · Cited by 7
Metharom, P., Martin, K., Kumar, A. H. S., Sawhney, N., Cronin, M. F., McCarthy, D. G., Maguire, A. R., & Caplice, N. M. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.01.037 · Cited by 7
Rapid Isolation of Dorsal Root Ganglion Macrophages
Yu, X., Leff, J., & Guan, Z. (2019) · Journal of Visualized Experiments · doi:10.3791/60023 · Cited by 8
Macrophage Epigenetic Memories of Early Life Injury Drive Neonatal Nociceptive PrimingPreprint
Dourson, A. J., Fadaka, A. O., Warshak, A. M., Paranjpe, A., Weinhaus, B., Queme, L. F., Hofmann, M. C., Evans, H. M., Donmez, O. A., Forney, C. R., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.13.528015 · Cited by 7
Conditional Loss of MEF2C Expression in Osteoclasts Leads to a Sex-Specific Osteopenic Phenotype
Maisuria, R., Norton, A., Shao, C., Bradley, E. W., & Mansky, K. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612686 · Cited by 6
Intravital multiphoton microscopy as a novel tool in the field of immunopharmacology
Morimoto, A., Kikuta, J., & Ishii, M. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107429 · Cited by 6
Cotugno, G., Formisano, P., Giacco, F., Colella, P., Bèguinot, F., & Auricchio, A. (2007) · Human Gene Therapy · doi:10.1089/hum.2006.116 · Cited by 6
A Monocytic Barrier to the Humanization of Immunodeficient Mice
Du, E. J., & Muench, M. O. (2023) · Current Stem Cell Research & Therapy · doi:10.2174/011574888x263597231001164351 · Cited by 5
Macrophages Modulate Optic Nerve Crush Injury Scar Formation and Retinal Ganglion Cell Function
Liu, Y., Liu, X., Dorizas, C. A., Hao, Z., & Lee, R. K. (2024) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.65.10.22 · Cited by 5
Skeletal muscle macrophage ablation in mice
Krall, J., Gibbs, K. W., Belfield, L. T., Liu, C., Purcell, L. D., Bivona, J. J., Poynter, M. E., Stapleton, R. D., Toth, M. J., & Files, D. C. (2022) · Journal of Immunological Methods · doi:10.1016/j.jim.2022.113329 · Cited by 5
Macrophages of multiple hematopoietic origins reside in the developing prostate
Feng, S., North, T. M., Wivell, P., Pletcher, A., Popratiloff, A. S., & Shibata, M. (2024) · Development · doi:10.1242/dev.203070 · Cited by 5
Evans, T. A., Barkauskas, D. S., & Silver, J. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.112972 · Cited by 5
Modulation of tumor inflammatory signaling and drug sensitivity by CMTM4
Xu, Y., Kang, K., Coakley, B. A., Eisenstein, S. G., Parveen, A., Mai, S., Wang, Y. S., Zheng, J., Boral, D., Mai, J., et al. (2025) · The EMBO Journal · doi:10.1038/s44318-024-00330-y · Cited by 6
Pro-inflammatory macrophages suppress HIV replication in humanized mice and ex vivo co-cultures
Baroncini, L., Muller, C. K. S., Kadzioch, N. P., Wolfensberger, R., Russenberger, D., Bredl, S., Mlambo, T., & Speck, R. F. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1439328 · Cited by 4
Chen, M., Tian, X., Xu, L., Wu, R., He, H., Zhu, H., Xu, W., & Wei, C. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.01.022 · Cited by 2
Kim, S. J., Kim, S., Fauziah, A. N., Park, J. M., Ryu, J. A., Yoon, S. R., Han, C., & Jung, S. K. (2025) · Applied Food Research · doi:10.1016/j.afres.2025.101243 · Cited by 3
Choe, H., Hausman, B. S., Hujer, K., Akkuş, O., Rather, P. N., Lee, Z., Bonomo, R., & Greenfield, E. M. (2022) · European Cells and Materials · doi:10.22203/ecm.v043a18 · Cited by 3
Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermúdez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L. J., Mees, B., et al. (2024) · European Journal of Immunology · doi:10.1002/eji.202350943 · Cited by 3
Ishii, T., Kawamura, S., Nishiyama, I., Kikuta, J., & Ishii, M. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-800-9_10 · Cited by 3
Microglial reactivity in brainstem chemosensory nuclei in response to hypercapnia
Eugenín, J. L., Beltrán-Castillo, S., Irribarra, E., Pulgar‐Sepúlveda, R., Abarca, N., & Rommy von Bernhardi, M. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1332355 · Cited by 3
Neuromuscular Polytrauma Pain is Resolved by Macrophage COX-2 Nanoimmunomodulation
Cortez, I., Gaffney, C. M., Vichare, R., Crelli, C. V., Liu, L., Lee, E. F., Edralin, J. D., Nichols, J. M., Pham, H. V., Mehdi, S., et al. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s460418 · Cited by 3
Bank, R. A. (2015) · Nature Materials · doi:10.1038/nmat4304 · Cited by 2
Buela, K.-A. G. (2015) · D-Scholarship@Pitt (University of Pittsburgh) · Cited by 2
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, M. M., Khoo, W. H., Ng, P. Y., Xiao, Y., Zamerli, J., Thatcher, P., Kyaw, W., Pathmanandavel, K., Grootveld, A. K., Moran, I., et al. (2021) · Yearbook of pediatric endocrinology · doi:10.1530/ey.18.5.12 · Cited by 2
Attenuation of Immune Suppression to Complement Glioma Immunotherapy
Field, C. S. (2016) · doi:10.26686/wgtn.17013761.v1 · Cited by 2
Chèvre, R. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2929-0_25 · Cited by 1
Nelson, C. A., Obray, J. D., Clarke, T. J., Brundage, J., Folsom, R. J., Moreno, C. M., Williams, P. E., Ford, L. H., Hope, S. I., Weber, K. S., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13102327 · Cited by 1
Development of an immunodeficient mouse that allows for conditional ablation of monocytic cells
Hui, A. J., Lai, K., Doyle, E. H., Rivera-Torruco, G., Gutierrez, A. G., Du, E. J., Meijer, Y. B. M., Smith, G., Gilfanova, R., Chung, K. G., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1699385 · Cited by 1
Straley, S. C. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-3561-7_31 · Cited by 1
Self-citationMacrophages and pathophysiology of bone cancers
Sousa, S., & Määttä, J. A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-416721-6.00009-1 · Cited by 1
Effects of immune cells on mesenchymal stem cells during fracture healing
Ehnert, S., Relja, B., Schmidt‐Bleek, K., Fischer, V., Ignatius, A. A., Linnemann, C., Rinderknecht, H., Huber-Lang, M. S., Kalbitz, M., Histing, T., et al. (2021) · World Journal of Stem Cells · doi:10.4252/wjsc.v13.i11.1670 · Cited by 1
Intravital Confocal Microscopy of Dermal Innate Immune Responses to Flea-Transmitted Yersinia pestis
Shannon, J. G., & Hinnebusch, B. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9541-7_5 · Cited by 1
Mountz, J. D., Li, J., & Hsu, H. (2011) · Arthritis & Rheumatism · doi:10.1002/art.34321 · Cited by 1
Tissue-Resident CD169+ macrophages as a frontline of host defense in Plasmodium infection
Gupta, P. (2017) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/70327
Kiyani, A., & Seki, E. (2015) · Wiley eBooks · doi:10.1002/9781118663387.ch4 · Cited by 1
Caspase-1 activates gasdermin A in non-mammals
Billman, Z. P., Kovacs, S. B., Wei, B., Kang, K., Cissé, O. H., & Miao, E. A. (2023) · doi:10.1101/2023.09.28.559989 · Cited by 1
Caspase-1 activates gasdermin A in all non-mammalsPreprint
Billman, Z. P., Kovacs, S. B., Wei, B., Kang, K., Cissé, O. H., & Miao, E. A. (2023) · eLife · doi:10.7554/elife.92362.1 · Cited by 1
Caspase-1 activates gasdermin A in non-mammals
Billman, Z. P., Kovacs, S. B., Wei, B., Kang, K., Cissé, O. H., & Miao, E. A. (2024) · doi:10.7554/elife.92362.3 · Cited by 1
Ye, Z. (2010) · UKnowledge (University of Kentucky)
THE EFFECT OF POLYCHLORINATED BIPHENYLS ON LIVER TUMOR PROMOTION: A ROLE FOR KUPFFER CELLS?
Bunaciu, R. P. (2005) · UKnowledge (University of Kentucky)
Christopher, M. J. (2010) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k76m34tv
Heterogeneity and Pliability of Tumor-educated Macrophages
Roberts, R. D. (2008) · The Knowledge Bank (The Ohio State University)
EUROPEAN SCHOOL OF MOLECULAR MEDICINE
Napoli, S. D. (2010)
The Paradoxical Roles of Cell Death Pathways in Immune Cells
McComb, S. (2013) · uO Research (University of Ottawa) · doi:10.20381/ruor-3097
Attenuation of Immune Suppression to Complement Glioma Immunotherapy
Field, C. S. (2016) · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare) · doi:10.26686/wgtn.17013761 · Cited by 1
Regulation of T Cell Death in Alloimmune-Mediated Vascular Rejection
von Rossum, A. (2015) · Summit (Simon Fraser University)
Regulation of a multipotent spinal cord progenitor population
Briona, L. K. (2014) · doi:10.33525/0t-5j4p-6cpv
The role of alveolar macrophages in Influenza A infection
Purnama, C. (2013) · doi:10.32657/10356/53722
Sidler, M. (2017) · TSpace (University of Toronto)
Sabel, B. O., Brand, K., Rueckel, J., Hoppe, B. F., Fink, N., & Bartling, S. H. (2020) · Acta Radiologica · doi:10.1177/0284185120943048
Atrophie, croissance et fonction musculaire : l'impact des leucocytes et de la triade RANK/RANKL/OPG
Dumont, N. A. (2013) · Corpus Université Laval (Université Laval)
Mantovani, A. (2014) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718203579.793489606
Zaidi, M., & Iqbal, J. Z. (2009) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1148895.605983
Hirschi, K. K. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734075201.793562733
Defining novel physiological roles for cardiac-residen Macrophages
Ávila, J. Á. N. (2020) · doi:10.4321/repisalud.10674
Vetter, I. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.737216984.793578085
Inducible and Repressible Systems for Transgene Expression
Schetelig, M. F., Lees, R. S., D'Amato, R., & Benedict, M. Q. (2022) · CABI eBooks · doi:10.1079/9781800621176.0002
1130 Investigating macrophage modulation in a murine model of soft tissue sarcoma
Hildebrand, K., Hildebrand, K. M., Zemp, F. J., Arcila, C. S., & Monument, M. J. (2022) · Regular and Young Investigator Award Abstracts · doi:10.1136/jitc-2022-sitc2022.1130
Immunomodulation under the lens of real‐time in vivo imaging
Bousso, P., & Grandjean, C. L. (2023) · European Journal of Immunology · doi:10.1002/eji.202249921
Caspase-1 activates gasdermin A in non-mammalsPreprint
Billman, Z. P., Kovacs, S. B., Wei, B., Kang, K., Cissé, O. H., & Miao, E. A. (2024) · eLife · doi:10.7554/elife.92362.2
Reviewer #2 (Public Review): Caspase-1 activates gasdermin A in non-mammals
Billman, Z. P., Kovacs, S. B., Wei, B., et al. (2024) · eLife · doi:10.7554/elife.92362.3.sa0
Author Response: Caspase-1 activates gasdermin A in non-mammals
Billman, Z. P., Kovacs, S. B., Wei, B., Kang, K., Cissé, O. H., & Miao, E. A. (2024) · eLife · doi:10.7554/elife.92362.3.sa3
Wang, H. H., Rajan, V., Wong, A., Epelman, S., & Zúñiga‐Pflücker, J. C. (2026) · eLife · doi:10.7554/elife.109219
Johnson, G., Hart, A., Sujansky, M., Graber, J. H., & Godwin, J. W. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.10.705144
Ma, X., Wang, E., Puviindran, V., Su, Z., Liu, X., Shimada, E., Yan, C., Liu, Y., Li, Z., Nadesan, P., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-69449-2
A Csf1r lineage gives rise to dermal lymphatic endothelial cellsPreprint
Canu, G., Correra, R., Plein, A., Denti, L., Fantin, A., & Ruhrberg, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.17.712362
Rôle des neutrophiles dans le contrôle des mammites chez l'animal cible et modèle
Rambault, M. (2022) · theses.fr (ABES) · doi:10.70675/e394badezaa07z46b4zb1fezf0f6c1ac3052
Metadata
- Authors
- Burnett, S. H., Kershen, E. J., Zhang, J., Zeng, L., Straley, S. C., Kaplan, A. M., & Cohen, D. A.
- Affiliations
- University of Kentucky (US)
- Corresponding author
- Cohen, Donald A
- Venue
- Journal of Leukocyte Biology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-01-14
- Volume
- 75
- Issue
- 4
- Pages
- 612-623
- ISSN
- 0741-5400 (ISSN-L)
- 1938-3673
- OpenAlex
- W2163279811
- Cited by
- 307
- References
- 44
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 21 · 2023: 17 · 2022: 15 · 2021: 17 · 2020: 18 · 2019: 12 · 2018: 17 · 2017: 20 · 2016: 13 · 2015: 22 · 2014: 21 · 2013: 18 · 2012: 11
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Leukocyte Biology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- NIH (HL69459, HL57399, 5T32AI049795)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Animal Genetics and Reproduction
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Life Sciences › Immunology and Microbiology › Immunology › Immunotoxicology and immune responses
- Keywords
- macrophage depletion, dendritic cells, bacterial clearance, splenomegaly, lymphadenopathy, thymic atrophy, extramedullary hematopoiesis, peritoneal adhesions, transgenic mice
- MeSH terms
- Animals, Bacterial Infections, Cell Count, Cells, Cultured, Dendritic Cells, Disease Models, Animal, Immunity, Cellular, Luminescent Proteins, Macrophages, Mice, Inbred C57BL, Mice, Transgenic, Promoter Regions, Genetic, Receptor, Macrophage Colony-Stimulating Factor, Tacrolimus, Apoptosis, Receptors, Nerve Growth Factor, fas Receptor, Dimerization, Tacrolimus Binding Proteins, Genes, Transgenic, Suicide, Green Fluorescent Proteins, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review