The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Fatigue associated with multiple sclerosis: diagnosis, impact and management
Abstract
In patients with multiple sclerosis (MS) fatigue is the most common symptom and one of the most disabling features. A s many as 40% have described it as the single most disabling symptom - a higher percentage than weakness, spasticity, motor problems, or bowel or bladder problems. The etiology and patho physiology of MS-related fatigue remain unknown. Studies have failed to demonstrate an association between MS-related fatigue and the level of disability, clinical disease subtype, or gender, although recent data show an association between MS-related fatigue and depression and quality of life. Imaging studies using positron emission tomography suggest that fatigue in MS is related to hypometabolism of specific brain areas, including the frontal and subcortical circuits. The impact of fatigue on patient functioning and quality of life clearly warrants intervention. In addition to nonpharmacologic measures, such as exercise and energy conservation strategies, several pharmacologic agents have been evaluated for their ability to reduce MS-related fatigue, including amantadine, central nervous system stimulants (pemoline), and the novel wake-promoting agent modafinil.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The impact of fatigue on patients with multiple sclerosis
Fisk, J. D., Pontefract, A., Ritvo, P. G., Archibald, C. J., & Murray, T. J. (1994) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100048691 · Cited by 1,025
Quality of life in patients with multiple sclerosis
Janardhan, V., & Bakshi, R. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00312-x · Cited by 489
Self-citationFatigue in multiple sclerosis and its relationship to depression and neurologic disability
Bakshi, R., Shaikh, Z. A., Miletich, R. S., Czarnecki, D., Dmochowski, J., Henschel, K., Janardhan, V, Dubey, N., & Kinkel, P. R. (2000) · Multiple Sclerosis Journal · doi:10.1177/135245850000600308 · Cited by 480
Self-citationModafinil in Obstructive Sleep Apnea-Hypopnea Syndrome: A Pilot Study in 6 Patients
Arnulf, I., Homeyer, P., Garma, L., Whitelaw, W. A., & Derenne, J.-P. (2009) · Respiration · doi:10.1159/000196661 · Cited by 64
Cited by
Diagnosis and Treatment of Multiple Sclerosis: A Review
McGinley, M. P., Goldschmidt, C. H., & Rae-Grant, A. D. (2021) · JAMA · doi:10.1001/jama.2020.26858 · Cited by 1,205
Fatigue and fatigability in neurologic illnesses: Proposal for a unified taxonomy
Kluger, B. M., Krupp, L. B., & Enoka, R. M. (2013) · Neurology · doi:10.1212/wnl.0b013e31827f07be · Cited by 1,036
Benedict, R. H. B., Wahlig, E., Bakshi, R., Fishman, I., Munschauer, F., Zivadinov, R., & Weinstock-Guttman, B. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2004.12.009 · Cited by 528
Self-citationPsychometric properties of the Fatigue Severity Scale and the Modified Fatigue Impact Scale
Learmonth, Y. C., Dlugonski, D., Pilutti, L. A., Sandroff, B. M., Klaren, R., & Motl, R. W. (2013) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2013.05.023 · Cited by 349
A Systematic Review of Modafinil: Potential Clinical Uses and Mechanisms of Action
Ballon, J. S., & Feifel, D. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0406 · Cited by 349
Metadata
- Authors
- Bakshi, R.
- Venue
- Multiple Sclerosis Journal
- Publisher
- SAGE Publications
- Published
- 2003-06
- Volume
- 9
- Issue
- 3
- Pages
- 219-227
- ISSN
- 1352-4585 (ISSN-L)
- 1477-0970
- OpenAlex
- W2003189347
- Cited by
- 446
- References
- 4
- FWCI
- 7.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Fatigue associated with multiple sclerosis: diagnosis, impact and management. https://app.cochat.ai/papers/10.1191/1352458503ms904oa
- The paper
- Bakshi, R. (2003). Fatigue associated with multiple sclerosis: diagnosis, impact and management. Multiple Sclerosis Journal. https://doi.org/10.1191/1352458503ms904oa
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
