A matched-control follow-up and family study of ‘puerperal psychoses’
Abstract
A hundred and ten women admitted to a psychiatric hospital within 90 days of childbirth were individually matched for age, psychiatric syndrome, and year of admission with women admitted to the same hospital with illnesses unrelated to childbirth. Both groups were followed up after a mean interval of nine years, and 72 matched pairs of patients for whom adequate information was obtained were then compared. The previous and subsequent psychiatric morbidity of these two groups, their subsequent obstetric careers, and the psychiatric morbidity of their first-degree relatives were all very similar. However, the puerperal women had significantly fewer relapses in the follow-up period, fewer committed suicide, and the psychiatric morbidity of their relatives tended to be lower. This better outcome was most marked in puerperal subjects with major depressions; those with manic disorders fared no better than controls. These results suggest that puerperal psychoses are basically the same as affective illnesses occurring at other times but, because childbirth is a uniquely potent precipitant of affective illness, some of those who develop puerperal episodes have a lesser genetic predisposition to affective illness than the generality of women with affective disorders.
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Symptom patterns in postpartum psychosis consistently differ from those in psychosis unrelated to childbearing.
“The symptom patterns in women with postpartum psychosis have consistently been reported to differ from women with psychosis not related to childbearing [22–24].”
From Perinatal mental illness: Definition, description and aetiology (2014) · cites this paper as [24]
Cites
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Kendell, R. E., Chalmers, J. C., & Platz, C. (1987) · British Journal of Psychiatry · doi:10.1192/bjp.150.5.662 · Cited by 1,119 · see citing works
Self-citationBrockington, I., & Kumar, R. C. (1982) · Medical Entomology and Zoology · Cited by 422 · see citing works
Puerperal Psychosis: Phenomena and Diagnosis
Brockington, I. F. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780320109013 · Cited by 284 · see citing works
The Symptomatology of Puerperal Illnesses
Dean, C., & Kendell, R. E. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.139.2.128 · Cited by 194 · see citing works
Self-citationPOSTPARTUM PSYCHOSES IN PATIENTS WITH MANIC DEPRESSIVE DISEASE
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Meitzer, E. S., & Kumar, R. (1985) · The British Journal of Psychiatry · doi:10.1192/bjp.147.6.647 · Cited by 101 · see citing works
PUERPERAL MENTAL DISORDERS IN MANIC‐DEPRESSIVE FEMALES
Bratfos, O., & Haug, J. O. (1966) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1966.tb01933.x · Cited by 99 · see citing works
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On the nosology of severe psychiatric post-partum disorders
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A comparison of puerperal psychosis and the schizophreniform variant of manic‐depression
Hays, P., & Douglass, A. B. (1984) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1984.tb02484.x · Cited by 26 · see citing works
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Perinatal mental illness: Definition, description and aetiology
O'Hara, M. W., & Wisner, K. L. (2014) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2013.09.002 · Cited by 986 · see citing works
Prevalence of suicidality during pregnancy and the postpartum
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A Review of Postpartum Psychosis
Sit, D., Rothschild, A. J., & Wisner, K. L. (2006) · Journal of Women's Health · doi:10.1089/jwh.2006.15.352 · Cited by 454 · see citing works
Suicide and other causes of mortality after post-partum psychiatric admission
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Symptomatology of affective and psychotic llnesses related to childbearing
Wisner, K. L., Peindl, K., & Hanusa, B. H. (1994) · Journal of Affective Disorders · doi:10.1016/0165-0327(94)90034-5 · Cited by 122 · see citing works
- Authors
- Platz, C., & Kendell, R. E.
- Affiliations
- Dartford And Gravesham NHS Trust (GB)
- University of Edinburgh (GB)
- Corresponding author
- Kendell, R. E.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1988-07
- Volume
- 153
- Issue
- 1
- Pages
- 90-94
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2152448656
- Cited by
- 84
- References
- 11
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 1 · 2022: 2 · 2019: 2 · 2015: 1 · 2014: 2 · 2013: 2 · 2012: 3
- FWCI
- 6.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Historical Psychiatry and Medical Practices
- Keywords
- postpartum psychosis, postpartum depression, mood disorders, major depressive disorder, manic disorder, suicide, relapse, family history (medicine), genetic susceptibility, long-term outcomes
- MeSH terms
- Affective Disorders, Psychotic, Bipolar Disorder, Depressive Disorder, Family Health, Female, Follow-Up Studies, Humans, Pregnancy, Psychotic Disorders, Puerperal Disorders
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