Cited by 315Schizophrenia research and treatmentMental Health and PsychiatryBipolar Disorder and Treatment

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Cognitive approach to depression and suicidal thinking in psychosis: I. Ontogeny of post-psychotic depression

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Birchwood, Max, Iqbal, Zaffer, Chadwick, Paul, Trower, Peter·2000·British Journal of Psychiatry

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Abstract

BACKGROUND: Depression in schizophrenia is a rather neglected field of study, perhaps because of its confused nosological status. Three course patterns of depression in schizophrenia, including post-psychotic depression (PPD), are proposed. AIMS: We chart the ontogeny of depression and psychotic symptoms from the acute psychotic episode over a 12-month period and test the validity of the proposed course patterns. METHOD: One hundred and five patients with ICD-10 schizophrenia were followed up on five occasions over 12 months following the acute episode, taking measures of depression, positive symptoms, negative symptoms, neuroleptic exposure and side-effects. RESULTS: Depression accompanied acute psychosis in 70% of cases and remitted in line with the psychosis; 36% developed PPD without a concomitant increase in psychotic symptoms. CONCLUSIONS: The results provided support for the validity of two of the three course patterns of depression in schizophrenia, including PPD. Post-psychotic depression occurs de novo without concomitant change in positive or negative symptoms.

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Vorontsova, N. (2015)

Authors: Birchwood, M., Iqbal, Z., Chadwick, P., & Trower, P.
Affiliations: University of Birmingham (GB)
ORCID: Birchwood, Max
Iqbal, Zaffer
Chadwick, Paul
Venue: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
Published: 2000-12
Volume: 177
Issue: 6
Pages: 516-521
ISSN: 0007-1250 (ISSN-L)
1472-1465
DOI: 10.1192/bjp.177.6.516
OpenAlex: W2125308310
Cited by: 315
References: 38
Citations by year: 2026: 1 · 2025: 3 · 2024: 7 · 2023: 10 · 2022: 7 · 2021: 12 · 2020: 4 · 2019: 8 · 2018: 9 · 2017: 7 · 2016: 10 · 2015: 18 · 2014: 10 · 2013: 16 · 2012: 17
FWCI: 7.67
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.cambridge.org/core/terms (unspecified, 6241 d)
Locations: The British Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords: schizophrenia, course of depression, cognitive approach, positive symptoms, negative symptoms, antipsychotic adverse effects
MeSH terms: Suicide Prevention, Adolescent, Adult, Aged, Depressive Disorder, Humans, Middle Aged, Psychotic Disorders, Schizophrenic Psychology, Suicide, Thinking, Disease Progression

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Cognitive approach to depression and suicidal thinking in psychosis: I. Ontogeny of post-psychotic depression

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