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Cognitive approach to depression and suicidal thinking in psychosis: I. Ontogeny of post-psychotic depression
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BACKGROUND: Depression in schizophrenia is a rather neglected field of study, perhaps because of its confused nosological status. Three course patterns of depression in schizophrenia, including post-psychotic depression (PPD), are proposed. AIMS: We chart the ontogeny of depression and psychotic symptoms from the acute psychotic episode over a 12-month period and test the validity of the proposed course patterns. METHOD: One hundred and five patients with ICD-10 schizophrenia were followed up on five occasions over 12 months following the acute episode, taking measures of depression, positive symptoms, negative symptoms, neuroleptic exposure and side-effects. RESULTS: Depression accompanied acute psychosis in 70% of cases and remitted in line with the psychosis; 36% developed PPD without a concomitant increase in psychotic symptoms. CONCLUSIONS: The results provided support for the validity of two of the three course patterns of depression in schizophrenia, including PPD. Post-psychotic depression occurs de novo without concomitant change in positive or negative symptoms.
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“The experience of psychosis is associated with increased levels of depression (Birchwood et al., 2000).”
From Acceptance and Commitment Therapy for depression following psychosis: An examination of clinically significant change (2015) · cites this paper as Birchwood et al., 2000
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“The finding that clinically significant changes in depression can occur in the context of psychosis in the absence of marked changes in positive and negative symptoms is consistent with previous research evidence suggesting that 'post-psychotic' depression emerges independently of positive symptom severity, relapse and negative symptoms (Birchwood et al., 2000; Iqbal et al., 2000).”
From Acceptance and Commitment Therapy for depression following psychosis: An examination of clinically significant change (2015) · cites this paper as Birchwood et al., 2000
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Metadata
- Authors
- Birchwood, M., Iqbal, Z., Chadwick, P., & Trower, P.
- Affiliations
- University of Birmingham (GB)
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2000-12
- Volume
- 177
- Issue
- 6
- Pages
- 516-521
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2125308310
- Cited by
- 315
- References
- 38
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 10 · 2022: 7 · 2021: 12 · 2020: 4 · 2019: 8 · 2018: 9 · 2017: 7 · 2016: 10 · 2015: 18 · 2014: 10 · 2013: 16 · 2012: 17
- FWCI
- 7.67
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Keywords
- schizophrenia, course of depression, cognitive approach, positive symptoms, negative symptoms, antipsychotic adverse effects
- MeSH terms
- Suicide Prevention, Adolescent, Adult, Aged, Depressive Disorder, Humans, Middle Aged, Psychotic Disorders, Schizophrenic Psychology, Suicide, Thinking, Disease Progression
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