Cited by 468Schizophrenia research and treatmentCounseling, Therapy, and Family DynamicsPsychiatric care and mental health services

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Early intervention services, cognitive–behavioural therapy and family intervention in early psychosis: systematic review

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Bird, Victoria, Premkumar, Preethi, Kendall, Tim, Whittington, Craig, Mitchell, Jonathan, Kuipers, Elizabeth·2010·British Journal of Psychiatry

DOI 10.1192/bjp.bp.109.074526PMC PMC2966501

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Abstract

Background: Early intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments. Aims: To evaluate the effectiveness of early intervention services, cognitive–behavioural therapy (CBT) and family intervention in early psychosis. Method: Systematic review and meta-analysis of randomised controlled trials of early intervention services, CBT and family intervention for people with early psychosis. Results: Early intervention services reduced hospital admission, relapse rates and symptom severity, and improved access to and engagement with treatment. Used alone, family intervention reduced relapse and hospital admission rates, whereas CBT reduced the severity of symptoms with little impact on relapse or hospital admission. Conclusions: For people with early psychosis, early intervention services appear to have clinically important benefits over standard care. Including CBT and family intervention within the service may contribute to improved outcomes in this critical period. The longer-term benefits of this approach and its component treatments for people with early and established psychosis need further research.

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Authors: Bird, V., Premkumar, P., Kendall, T., Whittington, C., Mitchell, J., & Kuipers, E.
Affiliations: Centre for Mental Health (GB)
King's College London (GB)
Royal College of Psychiatrists (GB)
University College London (GB)
Sheffield Health and Social Care NHS Foundation Trust (GB)
Corresponding author: Bird, Victoria
ORCID: Bird, Victoria
Premkumar, Preethi
Kendall, Tim
Whittington, Craig
Kuipers, Elizabeth
Venue: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
Published: 2010-11
Volume: 197
Issue: 5
Pages: 350-356
ISSN: 0007-1250 (ISSN-L)
1472-1465
DOI: 10.1192/bjp.bp.109.074526
PMC: PMC2966501
OpenAlex: W2135059788
Cited by: 468
References: 60
Citations by year: 2026: 20 · 2025: 19 · 2024: 28 · 2023: 30 · 2022: 21 · 2021: 28 · 2020: 39 · 2019: 40 · 2018: 39 · 2017: 35 · 2016: 31 · 2015: 34 · 2014: 34 · 2013: 33 · 2012: 22
FWCI: 3.09
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
creativecommons.org/licenses/by-nc/4.0/ (unspecified, 2619 d)
Locations: The British Journal of Psychiatry (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Nottingham Trent University's Institutional Repository (Nottingham Trent Repository) (submittedVersion)
Research Portal (King's College London) (submittedVersion, cc-by-nc)
Queen Mary Research Online (Queen Mary University of London) (submittedVersion, cc-by-nc)
Funders: Wellcome Trust (067427/z/02/z.)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
Keywords: early psychosis, early intervention services, cognitive behavioral therapy, family intervention, relapse, hospitalization, symptom severity, treatment engagement, duration of untreated psychosis
MeSH terms: Family Therapy, Hospitalization, Humans, Mental Health Services, Patient Acceptance of Health Care, Psychiatric Status Rating Scales, Psychotic Disorders, Severity of Illness Index, Time Factors, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Early Diagnosis, Secondary Prevention

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Early intervention services, cognitive–behavioural therapy and family intervention in early psychosis: systematic review

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