Advanced dental disease in people with severe mental illness: systematic review and meta-analysis
Open accessAbstract
Background: Psychiatric patients have increased comorbid physical illness. There is less information concerning dental disease in this population in spite of risk factors including diet and psychotropic side-effects (such as xerostomia). Aims: To compare the oral health of people with severe mental illness with that of the general population. Method: A systematic search for studies from the past 20 years was conducted using Medline, PsycINFO, Embase and article bibliographies. Papers were independently assessed. The primary outcome was total tooth loss (edentulousness), the end-stage of both untreated caries and periodontal disease. We also assessed dental decay through standardised measures: the mean number of decayed, missing and filled teeth (DMFT) or surfaces (DMFS). For studies lacking a control group we used controls of similar ages from a community survey within 10 years of the study. Results: We identified 21 papers of which 14 had sufficient data (n = 2784 psychiatric patients) and suitable controls (n = 31 084) for a random effects meta-analysis. People with severe mental illness had 3.4 times the odds of having lost all their teeth than the general community (95% CI 1.6–7.2). They also had significantly higher scores for DMFT (mean difference 6.2, 95% CI 0.6–11.8) and DMFS (mean difference 14.6, 95% CI 4.1–25.1). Fluoridated water reduced the gap in oral health between psychiatric patients and the general population. Conclusions: Psychiatric patients have not shared in the improving oral health of the general population. Management should include oral health assessment using standard checklists that can be completed by non-dental personnel. Interventions include oral hygiene and management of xerostomia.
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- Authors
- Kisely, S., Quek, L.-H., Pais, J., Lalloo, R., Johnson, N. W., & Lawrence, D.
- Affiliations
- Griffith University (AU)
- The University of Queensland (AU)
- The Kids Research Institute Australia (AU)
- Corresponding author
- Kisely, Steve
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2011-09
- Volume
- 199
- Issue
- 3
- Pages
- 187-193
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2070521055
- Cited by
- 193
- References
- 58
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 17 · 2023: 11 · 2022: 16 · 2021: 13 · 2020: 15 · 2019: 9 · 2018: 12 · 2017: 14 · 2016: 14 · 2015: 21 · 2014: 9 · 2013: 15 · 2012: 3
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- eSpace (Curtin University) (submittedVersion)
- Griffith Research Online (submittedVersion)
- Topics
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › Periodontics › Oral Health Pathology and Treatment
- Keywords
- dental diseases, severe mental illness, oral health, tooth loss, dental caries, periodontal disease, DMFT index, DMFS index, xerostomia, psychotropic side effects, fluoridated water, somatic comorbidity, oral health assessment
- MeSH terms
- Mental Disorders, Fluoridation, Humans, Stomatognathic Diseases, Oral Health, Oral Hygiene, Comorbidity, Health Status Disparities
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