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Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells
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Secreted ApoE is taken back up and transits through the recycling endosome pathway in multiple cell types, including astrocytes.
“However, this interpretation is complicated by the fact that secreted ApoE is taken back up and transits through the recycling endosome pathway in multiple cell types, including astrocytes [32–36].”
From ApoE lipoproteins in the central nervous system under homeostasis and role in Alzheimer’s disease and related disorders (2026) · cites this paper as [34]
The paper reports that internalized apoE traffics through the endosomal recycling compartment in CHO cells (Abstract; page unavailable). The Discussion also describes apoE recycling in hepatocytes and macrophages, but our copy does not establish transit through that compartment in those cells or address astrocytes. (LLM, conf=0.86)
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The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.
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Self-citationJi, Z.-S., Pitas, R. E., & Mahley, R. W. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.22.13452 · Cited by 134
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Cited by
Sorted by citations
Strickland, M. R., & Holtzman, D. M. (2026) · Molecular Neurodegeneration · doi:10.1186/s13024-026-00970-0
Metadata
- Authors
- Braun, N. A., Mohler, P. J., Weisgraber, K. H., Hasty, A. H., Linton, M. F., Yancey, P. G., Su, Y. R., Fazio, S., & Swift, L. L.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 2006-06
- Volume
- 47
- Issue
- 6
- Pages
- 1176-1186
- ISSN
- 0022-2275
- Cited by
- 18
- References
- 2
- Language
- en
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