Emerging role of Toll-like receptors in atherosclerosis

Atherosclerosis--an inflammatory disease

Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725

TLR4 links innate immunity and fatty acid-induced insulin resistance

Shi, H., Kokoeva, M. V., Inouye, K., Tzameli, I., Yin, H., & Flier, J. S. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28898 · Cited by 3,690

Points of control in inflammation

Nathan, C. (2002) · Nature · doi:10.1038/nature01320 · Cited by 2,738

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Lotze, M. T., & Tracey, K. J. (2005) · Nature reviews. Immunology · doi:10.1038/nri1594 · Cited by 2,490

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

Tzima, E., Irani-Tehrani, M., Kiosses, W. B., Dejana, E., Schultz, D., Engelhardt, B., Cao, G., DeLisser, H. M., & Schwartz, M. A. (2005) · Nature · doi:10.1038/nature03952 · Cited by 1,738

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

Ohashi, K., Burkart, V., Flohé, S. B., & Kolb, H. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.558 · Cited by 1,607

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Jiang, D., Liang, J., Fan, J., Yu, S., Chen, S., Luo, Y., Prestwich, G. D., Mascarenhas, M. M., Garg, H. G., Quinn, D. A., et al. (2005) · Nature Medicine · doi:10.1038/nm1315 · Cited by 1,401

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

Termeer, C., Benedix, F., Sleeman, J., Fieber, C., Voith, U., Ahrens, T., Miyake, K., Freudenberg, M., Galanos, C., & Simon, J. C. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20001858 · Cited by 1,378

The Extra Domain A of Fibronectin Activates Toll-like Receptor 4

Okamura, Y., Watari, M., Jerud, E. S., Young, D. W., Ishizaka, S. T., Rose, J., Chow, J. C., & Strauss, J. F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100099200 · Cited by 1,217

Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells

Lund, J. M., Sato, A., Akira, S., Medzhitov, R. M., & Iwasaki, A. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030162 · Cited by 1,197

Antiatherogenic Roles of Dietary Flavonoids Chrysin, Quercetin, and Luteolin

Basu, A., Das, A. S., Majumder, M., & Mukhopadhyay, R. (2016) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000380 · Cited by 40

TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts

Hamidi, S., Schäfer‐Korting, M., & Weindl, G. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.01.008 · Cited by 39

Gut Epithelial Metabolism as a Key Driver of Intestinal Dysbiosis Associated with Noncommunicable Diseases

Shelton, C. D., & Byndloss, M. X. (2020) · Infection and Immunity · doi:10.1128/iai.00939-19 · Cited by 43

The LPS2 mutation in TRIF is atheroprotective in hyperlipidemic low density lipoprotein receptor knockout mice

Richards, M. R., Black, A. S., Bonnet, D. J., Barish, G. D., Woo, C. W., Tabas, I. A., Curtiss, L. K., & Tobias, P. S. (2012) · Innate Immunity · doi:10.1177/1753425912447130 · Cited by 39

MicroRNAs in the regulation of immune cell functions – implications for atherosclerotic vascular disease

Zernecke, A. (2012) · Thrombosis and Haemostasis · doi:10.1160/th11-08-0603 · Cited by 38

Macrophages in Vascular Inflammation: Origins and Functions

Decano, J. L., Mattson, P. C., & Aikawa, M. (2016) · Current Atherosclerosis Reports · doi:10.1007/s11883-016-0585-2 · Cited by 35

A comprehensive genotype–phenotype interaction of different Toll-like receptor variations in a renal transplant cohort

Krüger, B., Banas, M. C., Walberer, A., Böger, C. A., Farkas, S. A., Hoffmann, U., Fischereder, M., Banas, B., & Krämer, B. K. (2010) · Clinical Science · doi:10.1042/cs20100190 · Cited by 35

Impact of Immunity on Coronary Artery Disease: An Updated Pathogenic Interplay and Potential Therapeutic Strategies

Laera, N., Malerba, P., Vacanti, G., Nardin, S., Pagnesi, M., & Nardin, M. (2023) · Life · doi:10.3390/life13112128 · Cited by 34

Toll-like receptor-dependent lipid body formation in macrophage foam cell formation

Nicolaou, G., & Erridge, C. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32833cacd5 · Cited by 33

Chronic allograft dysfunction: A model disorder of innate immunity

Land, W. G. (2013) · Biomedical Journal · doi:10.4103/2319-4170.117622 · Cited by 33

Reduced dietary intake of pro-inflammatory Toll-like receptor stimulants favourably modifies markers of cardiometabolic risk in healthy men

Herieka, M., Faraj, T., & Erridge, C. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.12.001 · Cited by 31

Expression of toll-like receptor 4 and its connection with type 2 diabetes mellitus

Taha, I. M., Allah, A. M. A., & Gayed, E. M. A. E. (2018) · Cellular and Molecular Biology · doi:10.14715/cmb/2018.64.13.4 · Cited by 31

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice

Leipner, J., Dederichs, T.-S., von Ehr, A., Rauterberg, S., Ehlert, C. A., Merz, J., Dufner, B., Hoppe, N., Krebs, K., Heidt, T., et al. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101250 · Cited by 31

Enhanced inflammatory responses to toll-like receptor 2/4 stimulation in type 1 diabetic coronary artery endothelial cells: the effect of insulin

Li, J., Jin, C., Cleveland, J. C., Ao, L., Xu, D., Fullerton, D. A., & Meng, X. (2010) · Cardiovascular Diabetology · doi:10.1186/1475-2840-9-90 · Cited by 31

Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization

Komi, D. E. A., Bot, I., Rodríguez-González, M., & Maurer, M. (2024) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-024-08981-9 · Cited by 30

Toll-like receptor 4 signaling in dysfunction of cardiac microvascular endothelial cells under hypoxia/reoxygenation

Zhang, Z., Li, W., Sun, D., Zhao, L., Zhang, R., Wang, Y., Zhou, X., Wang, H., & Cao, F. (2010) · Inflammation Research · doi:10.1007/s00011-010-0232-2 · Cited by 30

Synergy between Sphingosine 1-Phosphate and Lipopolysaccharide Signaling Promotes an Inflammatory, Angiogenic and Osteogenic Response in Human Aortic Valve Interstitial Cells

Fernández‐Pisonero, I., López, J., Onecha, E., Dueñas, A. I., Maeso, P. A., Crespo, M. S., Román, J. A. S., & García‐Rodríguez, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109081 · Cited by 30

Toll-Like Receptor 4: A Macrophage Cell Surface Receptor Is Activated By Trimethylamine-N-Oxide.

Hakhamaneshi, M. S., Abdolahi, A., Vahabzadeh, Z., Abdi, M., & Andalibi, P. (2021) · PubMed Central · doi:10.22074/cellj.2021.7849 · Cited by 29

microRNAs in the regulation of dendritic cell functions in inflammation and atherosclerosis

Busch, M., & Zernecke, A. (2012) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0864-5 · Cited by 29

Tim‐1 + B cells suppress T cell interferon‐gamma production and promote Foxp3 expression, but have impaired regulatory function in coronary artery disease

Xiaolong, G., He, H., Lin, L., Luo, G., Wen, Y., Xiang, D., & Qiu, J. (2017) · Apmis · doi:10.1111/apm.12729 · Cited by 29

TLR4 induces CREB-mediated IL-6 production via upregulation of F-spondin to promote vascular smooth muscle cell migration

Lee, G.-L., Wu, J.-Y., Yeh, C.-C., & Kuo, C.-C. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.04.040 · Cited by 27

SIRT1 inhibits monocyte adhesion to the vascular endothelium by suppressing Mac-1 expression on monocytes

Lee, S. J., Baek, S. E., Jang, M. A., & Kim, C. D. (2019) · Experimental & Molecular Medicine · doi:10.1038/s12276-019-0239-x · Cited by 27

Interactions Between Therapeutics for Metabolic Disease, Cardiovascular Risk Factors, and Gut Microbiota

Ding, Q., Tian, J., Li, M., Lian, F., Zhao, L., Wei, X., Han, L., Zheng, Y., Gao, Z., Yang, H., et al. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.530160 · Cited by 28

Association of a common TLR-6 polymorphism with coronary artery disease – implications for healthy ageing?

Hamann, L., Koch, A. H., Sur, S., Hoefer, N., Glaeser, C., Schulz, S., Gross, M. C., Franke, A., Nöthlings, U., Zacharowski, K. D., et al. (2013) · Immunity & Ageing · doi:10.1186/1742-4933-10-43 · Cited by 37

Inflammation in Atherosclerosis

Lauterbach, M., Labzin, L. I., & Latz, E. (2017) · Wiley-VCH eBooks · doi:10.1002/9783527692156.ch49 · Cited by 26

Isoliquiritigenin Alleviates Diabetic Kidney Disease via Oxidative Stress and the TLR4/NF‐κB/NLRP3 Inflammasome Pathway

Wang, Y., Yang, J. H., Chang, X., Xue, Y., Liu, G., Zhang, T., Chen, W., Fan, W., Tian, J., & Ren, X. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400215 · Cited by 28

Heat shock protein 27–derived atheroprotection involves reverse cholesterol transport that is dependent on GM‐CSF to maintain ABCA1 and ABCG1 expression in ApoE − / − mice.

Venu, V. K. P., Adijiang, A., Seibert, T., Chen, Y., Shi, C., Batulan, Z., & O’Brien, E. R. (2017) · The FASEB Journal · doi:10.1096/fj.201601188r · Cited by 24

TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome

Olejarz, W., Głuszko, A., Cyran, A., Bednarek-Rajewska, K., Proczka, R. M., Smith, D. F., Ishman, S. L., Migacz, E., & Kukwa, W. (2020) · Sleep And Breathing · doi:10.1007/s11325-020-02029-w · Cited by 24

Oat fiber supplementation alleviates intestinal inflammation and ameliorates intestinal mucosal barrier via acting on gut microbiota-derived metabolites in LDLR–/– mice

Gao, H. Y., Song, R., Jiang, H., Zhang, W., & Han, S. (2021) · Nutrition · doi:10.1016/j.nut.2021.111558 · Cited by 24

Cholesterol, Inflammasomes, and Atherogenesis

Ordovás, J. M., & Ordovás-Montañés, J. (2011) · Current Cardiovascular Risk Reports · doi:10.1007/s12170-011-0212-2 · Cited by 22

Ultrastructural Features of Human Atherosclerosis

Perrotta, I. D. (2011) · Ultrastructural Pathology · doi:10.3109/01913123.2011.592721 · Cited by 21

Advances in the Diagnosis of Large Vessel Vasculitis

Espígol‐Frigolé, G., Prieto‐González, S., Alba, M. A., Tavera-Bahillo, I., García‐Martínez, A., Gilabert, R., Hernández‐Rodríguez, J., & Cid, M. C. (2014) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2014.10.001 · Cited by 20

Association of TLR2 S450S and ICAM1 K469E polymorphisms with polycystic ovary syndrome (PCOS) and obesity

Ojeda, M. O., Martínez-García, M. Á., Alpañés, M., Luque‐Ramírez, M., & Escobar-Morreale, H. F. (2015) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2015.09.072 · Cited by 20

Host-microbiome interactions in response to a high-saturated fat diet and fish-oil supplementation in zebrafish adult

Arias-Jayo, N., Abecia, L., Lavín, J. L., Tueros, I., Arranz, S., Ramirez‐Garcia, A., & Pardo, M. Á. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103416 · Cited by 20

Hyperlipidemia, Disease Associations, and Top 10 Potential Drug Targets: A Network View

Rai, S., & Bhatnagar, S. (2016) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2015.0172 · Cited by 18

Цукровий діабет і атеросклероз. Роль процесів запалення у патогенезі (огляд літератури)

SOKOLOVA, L. K., PUSHKAREV, V. V., PUSHKAREV, V. V., Kovzun, О. I., & Tronko, M. D. (2017) · INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) · doi:10.22141/2224-0721.13.7.2017.115747 · Cited by 19

Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives

Toshchakov, V. Y., & Javmen, A. (2020) · Innate Immunity · doi:10.1177/1753425919844310 · Cited by 18

HDL inhibits saturated fatty acid mediated augmentation of innate immune responses in endothelial cells by a novel pathway

Zhang, W.-Y., Franco, D. A., Schwartz, E., D’Souza, K. M., Karnik, S. K., & Reaven, P. D. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.09.003 · Cited by 17

Blocking TIR Domain Interactions in TLR9 Signaling

Javmen, A., Szmacinski, H., Lakowicz, J. R., & Toshchakov, V. Y. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800194 · Cited by 18

Extracellular DNA Affects NO Content in Human Endothelial Cells

Efremova, L. V., Alekseeva, A. Y., Konkova, M. S., Kostyuk, S. V., Ershova, E. S., Smirnova, T. D., Конорова, И. Л., & Вейко, Н. Н. (2010) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-010-0906-3 · Cited by 17

The Effect of Probiotics on Lipid Metabolism

Zhang, Y., & Zhang, H. (2013) · InTech eBooks · doi:10.5772/51938 · Cited by 17

Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix

Seidl, S. E., Pessolano, L. G., Bishop, C. A., Best, M., Rich, C. B., Stone, P. J., & Schreiber, B. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0171711 · Cited by 16

TLR4 and MMP2 polymorphisms and their associations with cardiovascular risk factors in susceptibility to aortic aneurysmal diseases

Li, T., Jing, J., Sun, L. L., Jiang, B., Xin, S., Yang, J., & Yuan, Y. (2018) · Bioscience Reports · doi:10.1042/bsr20181591 · Cited by 15

Specific loss of Toll-like receptor 2 on bone marrow derived cells decreases atherosclerosis in LDL receptor null mice*The senior author, Stewart C. Whitman, passed away on 19 February 2010. The manuscript has been communicated by Ross W. Milne (e-mail: rmilne@ottawaheart.ca) and Yves L. Marcel (e-mail: ylmarcel@ottawaheart.ca), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada.

Hasu, M., Thabet, M., Tam, N. W. N., & Whitman, S. C. (2011) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y11-071 · Cited by 14

Attenuation of atherosclerotic complications by modulating inflammatory responses in hypercholesterolemic rats with dietary Njavara rice bran oil

Pushpan, C. K., Shalini, V., Sindhu, G., Parvathy, R., Jayalekshmy, A., & Helen, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.08.001 · Cited by 16

Microbial signature of plaque and gut in acute coronary syndrome

Pisano, E., Bugli, F., Severino, A., Pedicino, D., Sterbini, F. P., Martini, C., Maio, F. D., Vinci, R., Sacconi, A., Canonico, F., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-41867-y · Cited by 15

Cardiovascular Risk Reduction in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Dysfunction-Associated Steatohepatitis

Bernhard, J., Galli, L., Speidl, W. S., & Krychtiuk, K. A. (2025) · Current Cardiology Reports · doi:10.1007/s11886-024-02185-5 · Cited by 18

The Brave New World of Neuroimmune Biology

Berczi, I., Quintanar‐Stephano, A., & Kovács, K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-384691-4.00001-8 · Cited by 12

Cytokines and atherosclerosis – new research directions

Dutova, V. S., Saranchina, Y. V., Karpova, M. R., Kilina, O. Y., Polshcha, N. G., Кулакова, Т. С., & Владимирович, Х. Н. (2018) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2018-4-199-207 · Cited by 12

Sparstolonin B: A Unique Anti-Inflammatory Agent

Yepuri, N., Dhawan, R. K., Cooney, M., Pruekprasert, N., Meng, Q., & Cooney, R. N. (2019) · Shock · doi:10.1097/shk.0000000000001326 · Cited by 12

Metabolic Regulators of Vascular Inflammation

Fairman, G., Robichaud, S., & Ouimet, M. I. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.119.312582 · Cited by 11

Neuroimmunology of the Atherosclerotic Plaque: A Morphological Approach

Businaro, R. (2012) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-012-9421-9 · Cited by 11

Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity

Kochumon, S., Arefanian, H., Sindhu, S. T. A. K., Thomas, R., JACOB, T. K., Al-Sayyar, A., Shenouda, S., Al‐Rashed, F., Koistinen, H. A., Al‐Mulla, F., et al. (2022) · Cells · doi:10.3390/cells11244007 · Cited by 10

Role of intestinal microbiota in the formation of non-alcoholic fatty liver disease

Ахмедов, В. А., & Gaus, O. V. (2019) · Terapevticheskii arkhiv · doi:10.26442/00403660.2019.02.000051 · Cited by 10

Relationship between serine dipeptide lipids of commensal Bacteroidetes and atherosclerosis

Olsen, I. (2018) · Journal of Oral Microbiology · doi:10.1080/20002297.2018.1453224 · Cited by 10

Signaling pathways shaping the field of lipidomics

Ahi, E. P., & House, A. H. (2025) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2025.107053 · Cited by 9

Comparative transcriptome analysis reveals involvement of TLR-2 signaling in the pathogenesis of intracranial aneurysm

Fan, J., Yu, L., & Zhao, J. (2017) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2017.07.016 · Cited by 8

Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model

Schaftenaar, F. H., Amersfoort, J., Douna, H., Kröner, M. J., Foks, A. C., Bot, I., Slütter, B., van Puijvelde, G. H. M., Drijfhout, J. W., & Kuiper, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-53642-z · Cited by 8

A host lipase prevents lipopolysaccharide-induced foam cell formation

Feng, J., Jiang, W., Cheng, X., Zou, B., Varley, A. W., Liu, T., Qian, G., Zeng, W., Tang, J., Zhao, Q., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103004 · Cited by 8

Major Topics in Type 1 Diabetes

Nunes, K. P. (2015) · InTech eBooks · doi:10.5772/59335 · Cited by 8

NOS1‐derived nitric oxide facilitates macrophage uptake of low‐density lipoprotein

Roy, A., Banerjee, S., Saqib, U., & Baig, M. S. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28439 · Cited by 8

Tlr1‐13, Nod1/2 and antimicrobial gene expression in the epididymis and testis of rats with alloxan‐induced diabetes

Munipalli, S. B., Mounika, M. R., Aisha, J., & Yenugu, S. (2019) · Andrologia · doi:10.1111/and.13437 · Cited by 7

Decrease in the inflammatory cytokines of LPS-stimulated PBMCs of patients with atherosclerosis by a TLR-4 antagonist in the co-culture with HUVECs

Talepoor, A. G., Rastegari, B., Kalani, M., & Doroudchi, M. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108295 · Cited by 9

Beyond Pattern Recognition: TLR2 Promotes Chemotaxis, Cell Adhesion, and Migration in THP-1 Cells

Colleselli, K., Ebeyer-Masotta, M., Neuditschko, B., Stierschneider, A., Pollhammer, C., Potočnjak, M., Hundsberger, H., Herzog, F., & Wiesner, C. (2023) · Cells · doi:10.3390/cells12101425 · Cited by 8

TRIF is a regulator of TLR2-induced foam cell formation

Huang, B., Park, D., & Baek, S. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5647 · Cited by 7

Reduced soluble Toll-like receptors 2 in type 2 diabetes

Zaharieva, E., Velikova, T. V., Tsakova, A. D., & Kamenov, Z. A. (2017) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2017.1401642 · Cited by 7

MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages

Liu, M., Cao, Y., Hu, Y., Zhang, Z., Ji, S., Shi, L., & Tao, G. (2022) · Molecular Biotechnology · doi:10.1007/s12033-022-00484-2 · Cited by 6

Toll in the vessel wall—for better or worse?

Hansson, G. K., & Lundberg, A. M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019722108 · Cited by 6

Periodontal diseases and atherosclerosis: microecological, metabolic and immunological mechanisms of interconnection

Балмасова, И. П., Tsarev, V. N., Yushchuk, E. N., Dorovskikh, A. S., Малова, Е. С., Karakov, K. G., Elbekyan, K., & Arutyunov, S. D. (2020) · Immunologiya · doi:10.33029/0206-4952-2020-41-4-370-380 · Cited by 6

Obesity and atherosclerosis: the exosome link

Reiss, A. B., Glass, D. S., Voloshyna, I., Glass, A. D., Kasselman, L. J., & Leon, J. D. (2020) · Vessel Plus · doi:10.20517/2574-1209.2020.04 · Cited by 7

Antigenic Recognition by the Brain

Berczi, I. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-384691-4.00007-9 · Cited by 5

The Innate Immune System via Toll-Like Receptors (TLRs) in Type 1 Diabetes - Mechanistic Insights

Nunes, K. P., Guisbert, E., Szasz, T., & Webb, C. (2015) · InTech eBooks · doi:10.5772/61925 · Cited by 5

Endothelium: A Coordinator of Acute and Chronic Inflammation

Moreira, M. B., García‐Cardeña, G., Saffi, M. A. L., & Libby, P. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812348-5.00032-5 · Cited by 5

Two cosmoses, one universe: a narrative review exploring the gut microbiome's role in the effect of urban risk factors on vascular ageing

Bridge, L. A., Vargas, J. A. H., Trujillo-Cáceres, S. J., Beigrezaei, S., Chatelan, A., Salehi‐Abargouei, A., Muka, T., Uriza-Pinzón, J. P., Raeisi‐Dehkordi, H., Franco, O. H., et al. (2024) · Maturitas · doi:10.1016/j.maturitas.2024.107951 · Cited by 4

Coronary plaque vulnerability in statin-treated patients with elevated LDL-C and hs-CRP: optical coherence tomography study

Chamaria, S., Ueyama, H. A., Yasumura, K., Johnson, K. W., Vengrenyuk, Y., Okamoto, N., Barman, N., Bhatheja, S., Kapur, V., Hasan, C. M., et al. (2022) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-021-02238-8 · Cited by 4

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: pathophysiology and implications for cardiovascular disease

Chew, N., Muthiah, M. D., & Sanyal, A. J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99991-5.00003-6 · Cited by 4

TLR2 and IL 18 in obese diabetic patient

Mohamed, Z., & Abd-Elraheem, S. E. (2016) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000672 · Cited by 3

Modulatory role of atorvastatin against high-fat diet and zymosan-induced activation of TLR2/NF-ƙB signaling pathway in C57BL/6 mice.

Arya, P., Nabi, S., & Bhandari, U. (2021) · PubMed Central · doi:10.22038/ijbms.2021.55460.12409 · Cited by 4

The Role of Bacterial Extracellular Membrane Nanovesicles in Atherosclerosis: Unraveling a Potential Trigger

Lusta, K. A., Summerhill, V. I., Khotina, V. A., Sukhorukov, V. N., Glanz, V. Y., & Orekhov, A. N. (2024) · Current Atherosclerosis Reports · doi:10.1007/s11883-024-01206-6 · Cited by 4

Corilagin relieves atherosclerosis via the toll-like receptor 4 signaling pathway in vascular smooth muscle cells

Wang, Y., Li, Y., Chen, Y., Mao, J., Ji, J., Zhang, S., Liu, P., Pronyuk, K., Fisher, D. P., Dang, Y., et al. (2024) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320241254083 · Cited by 3

The prognostic potential of long noncoding RNA XIST in cardiovascular diseases: a review

Haybar, H., Sarbazjoda, E., Purrahman, D., Mahmoudian‐Sani, M., & Saki, N. (2024) · Personalized Medicine · doi:10.1080/17410541.2024.2360380 · Cited by 3

Endoplasmic Reticulum Stress in the Endothelium: A Contribution to Athero-Susceptibility

Stacchiotti, A., Favero, G., & Rezzani, R. (2013) · InTech eBooks · doi:10.5772/53024 · Cited by 3

Understanding the expression of Toll-like receptors in Asian Indians predisposed to coronary artery disease

Maitra, A., Shanker, J., Dash, D., Arvind, P., & Kakkar, V. V. (2011) · Archives of Medical Science · doi:10.5114/aoms.2011.25552 · Cited by 3

BIOFILTER AS A FUNCTIONAL ANNOTATION PIPELINE FOR COMMON AND RARE COPY NUMBER BURDEN

Kim, D., Lucas, A., Glessner, J., Verma, S. S., Bradford, Y., Li, R., Frase, A., Hakonarson, H. H., Peissig, P. L., Brilliant, M. H., et al. (2015) · Pacific Symposium on Biocomputing (PSB) · doi:10.1142/9789814749411_0033 · Cited by 3

Investigation of TLR4, TLR6, TLR7, and CD36 Expression on T lymphocytes in Coronary Artery Disease

Asgarbeik, S., Smiley, E., Gharehdaghi, E. E., Parichehreh-Dizaji, S., Hosseini, S. K., Esmaily, F., & Amoli, M. M. (2024) · GenoMed Connect · doi:10.69709/genomc.2024.197851 · Cited by 2

Contribution of toll-like receptor 2 and nicotinamide adenine dinucleotide phosphate oxidase to the trimethylamine N-oxide-induced inflammatory reactions in U937-derived macrophages.

Ahmadi, A., Vahabzadeh, Z., Moloudi, M. R., Farhadi, L., & Shirahmadi, S. (2021) · PubMed Central · doi:10.22122/arya.v17i0.2096 · Cited by 2

Coplanar PCB-induced inflammation and dietary interventions

Eske, K. (2013) · UKnowledge (University of Kentucky) · Cited by 2

Possible Pivotal Role of Latent Chronic T. gondii Infection in the Pathogenesis of Atherosclerosis

PRANDOTA, J. (2017) · Journal of Cardiology and Therapy · doi:10.17554/j.issn.2309-6861.2017.04.130 · Cited by 2

Insulin resistance in relation to inflammatory gene expression and metabolic features in apparently healthy obese individuals

Amiri, P., Naghizadeh, M., Baradaran, B., Saghafi‐Asl, M., Shanehbandi, D., & Mirmajidi, S. (2018) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-018-0626-1 · Cited by 2

Chemokines’ role in immunopathogenesis of atherosclerosis

Moskalev, A. V., Борисович, С. В., Vn, T., & Apchel, V. Y. (2018) · Bulletin of the Russian Military Medical Academy · doi:10.17816/brmma12310 · Cited by 2

Infections as Adjuvants for Autoimmunity: The Adjuvant Effect

Nhu, Q. M., & Rose, N. R. (2015) · Wiley eBooks · doi:10.1002/9781118663721.ch2 · Cited by 2

Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI Patients

Bratseth, V., Nordeng, J., Helseth, R., Solheim, S., Åkra, S., Arnesen, H., Chiva‐Blanch, G., & Seljeflot, I. (2022) · Biomedicines · doi:10.3390/biomedicines10092196 · Cited by 2

Leukocytosis as a Risk Factor for Coronary Artery Disease: Pathophysiology and Epidemiology

Amin, T., Rasool, M. H. U., OZKAN, B. I., Swaminathan, G., RAUF, F., PATRIZI, S., Sethi, A. K., Frishman, W. H., Aronow, W. S., & Ahmed, M. S. (2024) · Cardiology in Review · doi:10.1097/crd.0000000000000824 · Cited by 1

Targeting vascular smooth muscle cells with natural compounds to combat atherosclerosis

Qin, X., Zhou, Z., Zheng, Z., Wen, X., & Yang, H. (2026) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(26)61117-x · Cited by 2

Potential Role of Nuclear Factor κB in Cardiovascular Disease

Mishra, R. K. (2017) · Advances in medical diagnosis, treatment, and care (AMDTC) book series · doi:10.4018/978-1-5225-2092-4.ch003 · Cited by 1

Role of Toll-Like Receptors in Molecular and Cellular Mechanisms of Respiratory Diseases

Kanwar, I. L., Haider, T., Pandey, V., Gupta, P. N., & Soni, V. (2021) · Springer eBooks · doi:10.1007/978-981-33-6827-9_31 · Cited by 1

Toll like receptors (TLR) in autoimmune disease and atherosclerosis

Sopta, M. L. (2016) · Cited by 1

Adaptive (Hypothalamic) and Innate Immunoregulation

Berczi, I., Quintanar‐Stephano, A., & Kovács, K. (2011) · Advances in Neuroimmune Biology · doi:10.3233/nib-2011-028

Sterol biosynthesis pathway is part of the interferon host defence response

Blanc, M. (2011) · ERA

IL-25 and B cells in atherosclerosis

Mantani, P. T. (2014)

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

Mullick, A. E., Soldau, K., Kiosses, W. B., Bell, T. A., Tobias, P. S., & Curtiss, L. K. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071096 · Cited by 221

The Toll of Toll-Like Receptors, Especially Toll-Like Receptor 2, on Murine Atherosclerosis

Curtiss, L. K., & Tobias, P. S. (2007) · Current Drug Targets · doi:10.2174/138945007783220605 · Cited by 36

The Roles of Toll-Like Receptors in Atherosclerosis

Erridge, C. (2009) · Journal of Innate Immunity · doi:10.1159/000191413 · Cited by 59

2009 George L. Duff Memorial Lecture—The Toll of Toll-Like Receptors on Atherosclerosis

Curtiss, L. K. (2009) · Circulation · doi:10.1161/circ.120.suppl_18.a17-a

The Expression and Functions of Toll-Like Receptors in Atherosclerosis

Cole, J. E., Georgiou, E. X., & Monaco, C. G. (2010) · Mediators of Inflammation · doi:10.1155/2010/393946 · Cited by 180