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Cited by 391

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Neurobiological Consequences of Early Stress and Childhood Maltreatment: Are Results from Human and Animal Studies Comparable?

TEICHER, MARTIN H., TOMODA, AKEMI, ANDERSEN, SUSAN L.·2006·Annals of the New York Academy of Sciences

Abstract

Abstract: Recent studies have reported an association between exposure to childhood abuse or neglect and alterations in brain structure or function. One limitation of these studies is that they are correlational and do not provide evidence of a cause–effect relationship. Preclinical studies on the effects of exposure to early life stress can demonstrate causality, and can enrich our understanding of the clinical research if we hypothesize that the consequences of early abuse are predominantly mediated through the induction of stress responses. Exposure to early abuse and early stress has each been associated with the emergence of epileptiform electroencephalogram (EEG) abnormalities, alterations in corpous callosum area, and reduced volume or synaptic density of the hippocampus. Further, there is evidence that different brain regions have unique periods when they are maximally sensitive to the effects of early stress. To date, preclinical studies have guided clinical investigations and will continue to provide important insight into studies on molecular mechanisms and gene–environment interactions.

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Metadata

Authors
TEICHER, M. H., TOMODA, A., & ANDERSEN, S. L.
Venue
Annals of the New York Academy of Sciences
Publisher
Wiley
Published
2006-07
Volume
1071
Issue
1
Pages
313-323
ISSN
  • 0077-8923 (ISSN-L)
  • 1749-6632
OpenAlex
W2115762181
Cited by
391
References
50
FWCI
16.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Neurobiological Consequences of Early Stress and Childhood Maltreatment: Are Results from Human and Animal Studies Comparable? https://app.cochat.ai/papers/10.1196/annals.1364.024
The paper
TEICHER, M. H., TOMODA, A., & ANDERSEN, S. L. (2006). Neurobiological Consequences of Early Stress and Childhood Maltreatment: Are Results from Human and Animal Studies Comparable? Annals of the New York Academy of Sciences. https://doi.org/10.1196/annals.1364.024

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.