Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 77

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Transcriptional Regulation of Telomerase Activity: Roles of the the Ets Transcription Factor Family

DWYER, JULIE, LI, HE, XU, DAKANG, LIU, JUN‐PING·2007·Annals of the New York Academy of Sciences
DOI 10.1196/annals.1396.022
Open this paper in CoChat — free account

Abstract

Abstract: Telomerase maintains telomeres to preclude cell senescence. It remains elusive how telomerase activity is repressed in differentiated cells, but retained at high levels in stem cells and cancer. Recent studies suggest that the Ets transcription factor family, downstream of the mitogen signaling pathways of MAP kinase, regulates telomerase activity at the gene transcription level of human telomerase reverse transcriptase (hTERT). Several Ets transcription factors are involved in regulating hTERT gene expression, both directly and indirectly through the proto‐oncogene c‐myc. ER81 may mediate telomerase activation in telomerase‐negative fibroblasts stimulated by oncogenes Her2/Neu, Ras, and Raf. Ets2 may also play an important role in regulating the hTERT gene; but further studies are required to decipher the mechanisms in the regulation of telomerase activity.

Overview

Integrity signals

Registry

Crossref · 10.1196/annals.1396.022

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 58

  1. 10.1016/S0092-8674(01)00492-5 · DOI
  2. 10.1016/j.febslet.2004.11.036 · DOI · Paper page
  3. 10.1002/path.2090 · DOI
  4. 10.1126/science.279.5349.349 · DOI · Paper page
  5. 10.1038/sj.onc.1209905 · DOI
  6. 10.1096/fasebj.13.15.2091 · DOI
  7. 10.1016/j.mce.2005.05.009 · DOI
  8. 10.1038/sj.cr.7310098 · DOI
  9. 10.1016/j.ccr.2004.12.012 · DOI
  10. 10.1016/j.ejca.2004.11.024 · DOI
  11. 10.1074/jbc.M502782200 · DOI
  12. 10.1007/s10549-005-9043-5 · DOI
  13. 10.1016/S1566-3124(01)08003-8 · DOI
  14. Liu J.P., 2002, Telomeres and Telomerases: Cancer and Biology, 134
  15. 10.1126/science.277.5328.955 · DOI · Paper page
  16. 10.1016/S0092-8674(00)80538-3 · DOI · Paper page
  17. 10.1016/S0092-8674(00)81933-9 · DOI
  18. 10.1126/science.275.5302.973 · DOI
  19. 10.1093/hmg/6.12.2011 · DOI
  20. 10.1038/sj.onc.1205083 · DOI
  21. 10.1016/S0968-0004(02)02206-5 · DOI · Paper page
  22. 10.1101/gad.13.7.817 · DOI
  23. 10.1074/jbc.M511067200 · DOI
  24. 10.1074/jbc.273.50.33436 · DOI
  25. 10.1074/jbc.272.27.16729 · DOI
  26. 10.1093/hmg/8.1.137 · DOI
  27. Horikawa I., 1999, Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene [In Process Citation], Cancer Res., 59, 826
  28. Takakura M., 1999, Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells, Cancer Res., 59, 551
  29. 10.1111/j.1471-4159.2005.03439.x · DOI
  30. 10.1074/jbc.M602381200 · DOI
  31. 10.1073/pnas.071043198 · DOI
  32. Sarkar P., 2006, Activation of telomerase in BeWo cells by estrogen and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin in co‐operation with c‐Myc, Int. J. Oncol., 28, 43
  33. Xu D., 2006, Methods in Molecular Biology: telomerase Inhibition: strategies and Protocols
  34. 10.1038/sj.onc.1205509 · DOI
  35. 10.1128/MCB.24.1.25-35.2004 · DOI
  36. Wang Z., 2000, Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen‐activated protein kinase signaling pathway [In Process Citation], Cancer Res., 60, 5376
  37. Alfonso‐De Matte M.Y., 2002, Telomerase is regulated by c‐Jun NH2‐terminal kinase in ovarian surface epithelial cells, Cancer Res., 62, 4575
  38. 10.1038/sj.onc.1204039 · DOI
  39. 10.1002/jcb.20012 · DOI
  40. 10.1038/sj.onc.1208626 · DOI
  41. 10.1016/j.ejca.2005.10.018 · DOI
  42. 10.1038/35099076 · DOI · Paper page
  43. 10.1158/1078-0432.CCR-04-1192 · DOI
  44. 10.1016/j.ejca.2005.08.013 · DOI
  45. Sapi E., 1998, Ets‐2 transdominant mutant abolishes anchorage‐independent growth and macrophage colony‐stimulating factor‐stimulated invasion by BT20 breast carcinoma cells, Cancer Res., 58, 1027
  46. 10.1038/sj.onc.1203946 · DOI
  47. 10.1093/nar/gkh744 · DOI
  48. 10.1038/sj.onc.1208761 · DOI
  49. Neznanov N., 1999, A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice, Cancer Res., 59, 4242
  50. 10.1038/sj.onc.1202220 · DOI
  51. 10.1016/S0378-1119(02)01156-3 · DOI
  52. 10.1093/emboj/cdf413 · DOI
  53. 10.1038/sj.leu.2402607 · DOI
  54. 10.1016/S0014-4800(03)00092-3 · DOI
  55. Roussel M.F., 1994, Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F‐1, Oncogene, 9, 405
  56. Takahashi A., 2003, EWS/ETS fusions activate telomerase in Ewing's tumors, Cancer Res., 63, 8338
  57. 10.1016/j.canlet.2004.07.020 · DOI
  58. 10.1016/j.ejca.2006.02.014 · DOI

Cited by

See all 77

Metadata

Authors
DWYER, J., LI, H., XU, D., & LIU, J.
Venue
Annals of the New York Academy of Sciences
Publisher
Wiley
Published
2007-10
Volume
1114
Issue
1
Pages
36-47
ISSN
  • 0077-8923
  • 1749-6632
DOI
10.1196/annals.1396.022
Cited by
77
References
7
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 31 d)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review