The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

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Oxygen, oxidative stress, hypoxia, and heart failure

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Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy

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Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function

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Roles of Dihydrolipoamide Dehydrogenase in Health and Disease

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Activation of aldehyde dehydrogenase-2 improves ischemic random skin flap survival in rats

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The pH sensitivity of H2O2 metabolism in skeletal muscle mitochondria

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Mitophagy in Neurodegeneration: An Opportunity for Therapy?

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Modulation of the conformational state of mitochondrial complex I as a target for therapeutic intervention

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Level of blood cell-free circulating mitochondrial DNA as a novel biomarker of acute myocardial ischemia

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Mitophagy in the Hippocampus Is Excessive Activated After Cardiac Arrest and Cardiopulmonary Resuscitation

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Reactive Oxygen Species in the Botrytis – Host Interaction

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Isoflurane Anesthesia Initiated at the Onset of Reperfusion Attenuates Oxidative and Hypoxic-Ischemic Brain Injury

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Oxidative stress, autophagy and airway ion transport

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Exercise Reveals Proline Dehydrogenase as a Potential Target in Heart Failure

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Homozygous damaging SOD2 variant causes lethal neonatal dilated cardiomyopathy

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Detection of hydrogen peroxide production in the isolated rat lung using Amplex red

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Mitochondrial DNA A3243G variant-associated retinopathy: Current perspectives and clinical implications

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Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders

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Kaempferol Alleviates Mitochondrial Damage by Reducing Mitochondrial Reactive Oxygen Species Production in Lipopolysaccharide-Induced Prostate Organoids

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Dietary Antioxidants and the Mitochondrial Quality Control: Their Potential Roles in Parkinson’s Disease Treatment

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ACE2 and energy metabolism: the connection between COVID-19 and chronic metabolic disorders

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Regulation of immune cell function by nicotinamide nucleotide transhydrogenase

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Butein Ameliorates Oxidative Stress in H9c2 Cardiomyoblasts through Activation of the NRF2 Signaling Pathway

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Importance of Locations of Iron Ions to Elicit Cytotoxicity Induced by a Fenton-Type Reaction

Igarashi, K., Shoji, Y., Sekine‐Suzuki, E., Ueno, M., Matsumoto, K., Nakanishi, I., & Fukui, K. (2022) · Cancers · doi:10.3390/cancers14153642 · Cited by 26

Molecular therapy of cardiac ischemia–reperfusion injury based on mitochondria and ferroptosis

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Protective effect of Phyllanthus fraternus against bromobenzene induced mitochondrial dysfunction in rat liver mitochondria

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Chronic Glucocorticoid Exposure-Induced Epididymal Adiposity Is Associated with Mitochondrial Dysfunction in White Adipose Tissue of Male C57BL/6J Mice

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Qo site of mitochondrial complex III is the source of increased superoxide after transient exposure to hydrogen peroxide

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Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation

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N‐acetylcysteine alleviated paraquat‐induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells

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Breaking free from free radicals: harnessing the power of natural antioxidants for health and disease prevention

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Platelet rich plasma efficiently substitutes the beneficial effects of serum during in vitro oocyte maturation and helps maintain the mitochondrial activity of maturing oocytes

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Site-specific mitochondrial dysfunction in neurodegeneration

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N-acetylcysteine alters substrate metabolism during high-intensity cycle exercise in well-trained humans

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Effect of paraquat-induced oxidative stress on gene expression and aging of the filamentous ascomycete Podospora anserina

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Structural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry: Implications for the structural basis of E3 deficiency

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Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

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Extreme Heat Exposure Induced Acute Kidney Injury through NLRP3 Inflammasome Activation in Mice

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Sestrins: Darkhorse in the regulation of mitochondrial health and metabolism

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Mitochondrial-nuclear cross-talk in the human brain is modulated by cell type and perturbed in neurodegenerative disease

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Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway

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Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells

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Batten disease is linked to altered expression of mitochondria-related metabolic molecules

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Pheophorbide a: A photosensitizer with immunostimulating activities on mouse macrophage RAW 264.7 cells in the absence of irradiation

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N-acetylcysteine Treatment Prevents the Up-Regulation of MnSOD in Chronically Hypoxic Rat Hearts

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Moderately decreased maternal dietary energy intake during pregnancy reduces fetal skeletal muscle mitochondrial biogenesis in the pigs

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Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics

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PARKIN modifies peripheral immune response and increases neuroinflammation in active experimental autoimmune encephalomyelitis (EAE)

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Redox Regulation of Calcium Signaling in Cancer Cells by Ascorbic Acid Involving the Mitochondrial Electron Transport Chain

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Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review)

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Dry-Cured Ham-Derived Peptide (Asp–Leu–Glu–Glu) Exerts Cytoprotective Capacity in Human Intestinal Epithelial Caco-2 Cells

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Mechanism of Antioxidant Activity

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Modulation of Cell Death in Age-Related Diseases

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New therapeutic targets for amyotrophic lateral sclerosis

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Zinc wave during the treatment of hypoxia is required for initial reactive oxygen species activation in mitochondria.

Slepchenko, K. G., Lu, Q., & Li, Y. V. (2016) · PubMed Central · Cited by 21

Mitochondrial Genetic Variation in Iranian Infertile Men with Varicocele.

Heidari, M., Khatami, M., Danafar, A., Dianat, T., Farahmand, G., & Talebi, A. R. (2016) · PubMed Central · doi:10.22074/ijfs.2016.5047 · Cited by 21

Myoglobin, expressed in brown adipose tissue of mice, regulates the content and activity of mitochondria and lipid droplets

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Mitochondrial respiration reduces exposure of the nucleus to oxygen

Mori, M. P., Penjweini, R., Ma, J., Alspaugh, G., Andreoni, A., Kim, Y., Wang, P., Knutson, J. R., & Hwang, P. M. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.103018 · Cited by 19

Glycolytic oscillations in single ischemic cardiomyocytes at near anoxia

Ganitkevich, V., Mattea, V., & Benndorf, K. (2010) · The Journal of General Physiology · doi:10.1085/jgp.200910332 · Cited by 21

Lin28a enhances in vitro osteoblastic differentiation of human periosteum‐derived cells

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NADH-linked mitochondrial respiration in the developing mouse brain is sex-, age- and tissue-dependent

Arias‐Reyes, C., Losantos-Ramos, K., Gonzales, M., Furrer, D., & Soliz, J. (2019) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2019.05.011 · Cited by 20

microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract

Liu, Y., Liu, Y., & Liu, Y. (2019) · Medical Science Monitor · doi:10.12659/msm.916881 · Cited by 20

Mitochondrial calcium in command of juggling myriads of cellular functions

Singh, S., & Mabalirajan, U. (2021) · Mitochondrion · doi:10.1016/j.mito.2020.12.011 · Cited by 20

Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation

Beyer, K., Lie, S. A., Bjørndal, B., Berge, R. K., Svardal, A. M., Brun, J. G., & Bolstad, A. I. (2021) · Scientific Reports · doi:10.1038/s41598-021-84122-y · Cited by 21

Responses of sperm mitochondria functionality in animals to thermal stress: The mitigating effects of dietary natural antioxidants

Abdelnour, S. A., Swelum, A. A., Sindi, R. A., Barkat, R. A., Khalifa, N. E., Amin, A. A., El‐Raghi, A. A., Tufarelli, V., Losacco, C., & El-Hack, M. E. A. (2022) · Reproduction in Domestic Animals · doi:10.1111/rda.14193 · Cited by 19

Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1

Wang, Y., Zhou, L., Li, Y., Wang, Z., Li, Y., Zhang, Y., Wang, Y., Liu, G., & Shen, Y. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3966-14.2015 · Cited by 19

Restoration of Mitochondrial Dysfunction in 6-Hydroxydopamine Induced Parkinson’s disease: a Complete Review

Mehan, S., Kaur, G., Dudi, R., Rajput, M., & Kalra, S. (2017) · Open Journal of Parkinson s Disease and Treatment · doi:10.17352/ojpdt.000001 · Cited by 19

How N-Acetylcysteine Supplementation Affects Redox Regulation, Especially at Mitohormesis and Sarcohormesis Level: Current Perspective

Devrim-Lanpir, A., Hill, L., & Knechtle, B. (2021) · Antioxidants · doi:10.3390/antiox10020153 · Cited by 20

The Link Between Energy-Related Sensations and Metabolism: Implications for Treating Fatigue

Filippi, M., Krähenmann, R., & Fissler, P. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.920556 · Cited by 22

Dissolved iron released from nanoscale zero-valent iron (nZVI) activates the defense system in bacterium Pseudomonas putida, leading to high tolerance to oxidative stress

Yeap, C. S. Y., Nguyen, N. H. A., Špánek, R., Too, C. C., Beneš, V., Provazník, J., Černík, M., & Ševců, A. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129627 · Cited by 18

Methylene Blue Induces Antioxidant Defense and Reparation of Mitochondrial DNA in a Nrf2-Dependent Manner during Cisplatin-Induced Renal Toxicity

Samoylova, N. A., Gureev, A. P., & Popov, V. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076118 · Cited by 21

Dietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs

He, W., Liu, X., Feng, Y., Ding, H., Sun, H., Li, Z., & Shi, B. (2024) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-024-01014-7 · Cited by 22

Enhancement of Autophagy and Solubilization of Ataxin-2 Alleviate Apoptosis in Spinocerebellar Ataxia Type 2 Patient Cells

Wardman, J. H., Henriksen, E. E., Marthaler, A. G., Nielsen, J. E., & Nielsen, T. T. (2020) · The Cerebellum · doi:10.1007/s12311-019-01092-8 · Cited by 17

Potassium is a potential toxicant for Arabidopsis thaliana under saline conditions

Zhao, W., Faust, F., & Schubert, S. (2020) · Journal of Plant Nutrition and Soil Science · doi:10.1002/jpln.201900491 · Cited by 18

Increased glutathione utilization augments tumor cell proliferation in Waldenstrom Macroglobulinemia

Jalali, S., Shi, J., BUKO, A. M., Ahsan, N., Paludo, J., Serres, M. R., Wellik, L. E., Abeykoon, J. P., Kim, H.-J., Tang, X., et al. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101657 · Cited by 19

Ectromelia Virus Affects Mitochondrial Network Morphology, Distribution, and Physiology in Murine Fibroblasts and Macrophage Cell Line

Gregorczyk-Zboroch, K. P., Wyżewski, Z., Szczepanowska, J., Toka, F. N., Mielcarska, M. B., Bossowska-Nowicka, M., Gieryńska, M. M., Boratyńska-Jasińska, A., Struzik, J., Niemiałtowski, M., et al. (2018) · Viruses · doi:10.3390/v10050266 · Cited by 19

Adverse Outcome Pathway on Inhibition of the mitochondrial complex I of nigro-striatal neurons leading to parkinsonian motor deficits

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Reactive oxygen species in cell signaling and cell death: A redox perspective on metabolic and inflammatory disorders

Deepak, K., Shee, M., Roy, P., & Mandal, M. (2026) · Cell Death · doi:10.1016/j.celld.2026.100009 · Cited by 19

Decreased hydrogen peroxide production and mitochondrial respiration in skeletal muscle but not cardiac muscle of the green-striped burrowing frog, a natural model of muscle disuse

Reilly, B. D., Hickey, A. J., Cramp, R. L., & Franklin, C. E. (2013) · Journal of Experimental Biology · doi:10.1242/jeb.096834 · Cited by 17

Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions

Subasinghe, S. A. A. S., Pautler, R. G., Samee, M. A. H., Yustein, J. T., & Allen, M. J. (2022) · Biosensors · doi:10.3390/bios12070478 · Cited by 18

Cardioprotective Effects of 6-Gingerol against Alcohol-Induced ROS-Mediated Tissue Injury and Apoptosis in Rats

Ganjikunta, V. S., Maddula, R. R., Shanmugam, B., Ravi, S., Shanmugam, K. R., Venkatrayulu, C., Kesireddy, S. R., Zhe, Z., & Korivi, M. (2022) · Molecules · doi:10.3390/molecules27238606 · Cited by 18

Host-Derived Cytotoxic Agents in Chronic Inflammation and Disease Progression

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Resolving Contributions of Oxygen‐Consuming and ROS‐Generating Enzymes at the Synapse

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