Hypoxic Radiosensitization: Adored and Ignored

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Items 101–200 of 617

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2. Importance of hemoglobin concentration and its modification for the outcome of head and neck cancer patients treated with radiotherapy
   Camilla Molich Hoff · 2012 · Acta Oncologica
3. Hypoxia and Predicting Radiation Response
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4. Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems
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5. Long-Term Outcomes of Radical Radiation Therapy with Hypoxia Modification with Biomarker Discovery for Stratification: 10-Year Update of the BCON (Bladder Carbogen Nicotinamide) Phase 3 Randomized Trial (ISRCTN45938399)
   Yee Pei Song, Hitesh B. Mistry, Joely J. Irlam, Helen R. Valentine, Lingjian Yang, Brian S. Lane, Catharine West, Ananya Choudhury, Peter Hoskin · 2021 · International Journal of Radiation Oncology*Biology*Physics
6. Hypoxia-responsive block copolymer radiosensitizers as anticancer drug nanocarriers for enhanced chemoradiotherapy of bulky solid tumors
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7. Individualization of cancer treatment from radiotherapy perspective
   Ala Yaromina, Mechthild Krause, Michael A. Baumann · 2012 · Molecular Oncology
8. Hafnium-Based Metal–Organic Framework Nanoparticles as a Radiosensitizer to Improve Radiotherapy Efficacy in Esophageal Cancer
   Zhou Wei, Zhulong Liu, Nana Wang, Xue Chen, Xiaozheng Sun, Yufeng Cheng · 2022 · ACS Omega
9. Implications of understanding cancer stem cell (CSC) biology in head and neck squamous cell cancer.
   Suhail I. Sayed, Raghav C Dwivedi, R. Katna, A. Garg, K. Pathak, C. Nutting, P. Rhys-Evans, K. Harrington, R. Kazi · 2011 · Oral Oncology
10. Identifying hypoxia in human tumors: A correlation study between 18 F-FMISO PET and the Eppendorf oxygen-sensitive electrode
    Lise Saksø Mortensen, Simon Buus, Marianne Nordsmark, Lise Bentzen, Ole Lajord Munk, Susanne Keiding, Jens Overgaard · 2010 · Acta Oncologica
11. Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302
    Jonathan W. Wojtkowiak, Heather C Cornnell, Shingo Matsumoto, Keita Saito, Yoichi Takakusagi, Prasanta Dutta, MunJu Kim, Xiaomeng Zhang, Rafael A. Leos, Kate M. Bailey et al. · 2015 · Cancer & Metabolism
12. Trial Watch: Immunotherapy plus radiation therapy for oncological indications
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13. Ozone Therapy as Adjuvant for Cancer Treatment: Is Further Research Warranted?
    Bernardino Clavo, Norberto Santana-Rodríguez, Pedro Llontop, Dominga Gutiérrez, Gerardo Suárez, Laura López, Gloria Rovira, Gregorio Martı́nez-Sánchez, Esteban González, Ignacio J. Jorge et al. · 2018 · Evidence-based Complementary and Alternative Medicine
14. PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response
    Liang Xie, Xinchun Pi, Ashutosh Mishra, Guo‐Hua Fong, Junmin Peng, Cam Patterson · 2012 · Journal of Clinical Investigation
15. Hypoxia Gene Expression Signatures as Prognostic and Predictive Markers in Head and Neck Radiotherapy
    Kasper Toustrup, Brita Singers Sørensen, Jan Alsner, Jens Overgaard · 2012 · Seminars in Radiation Oncology
16. Neoadjuvant versus adjuvant treatment: which one is better for resectable esophageal squamous cell carcinoma?
    Yaping Xu, Xinmin Yu, Qixun Chen, Weimin Mao · 2012 · World Journal of Surgical Oncology
17. miRNAs: micro-managers of anticancer combination therapies
    Judy R. Van Beijnum B, Elisa Giovannetti, Dennis Poel, Patrycja M. Nowak-Sliwinska, Arjan W. Griffioen · 2017 · Angiogenesis
18. Clinical Development of Novel Drug–Radiotherapy Combinations
    Saif S. Ahmad, Marka R. Crittenden, Phuoc Tho Tran, Paul Gustav Kluetz, Gideon Michael Blumenthal, Helen Bulbeck, Richard D. Baird, Kaye Janine Williams, Tim Illidge, Stephen M. Hahn et al. · 2018 · Clinical Cancer Research
19. NCI–RTOG Translational Program Strategic Guidelines for the Early-Stage Development of Radiosensitizers
    Yaacov Richard Lawrence, Bhadrasain Vikram, James J. Dignam, Arnab Chakravarti, Mitchell X. Machtay, Boris Freidlin, Naoko Takebe, Walter John Curran, Søren Møller Bentzen, Paul G Okunieff et al. · 2012 · JNCI Journal of the National Cancer Institute
20. Combining angiogenesis inhibition and radiotherapy: A double-edged sword
    Esther A. Kleibeuker, Arjan W. Griffioen, Henk M.W. Verheul, Ben J. Slotman, Victor L. Thijssen · 2012 · Drug Resistance Updates
21. Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: A comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry
    Ly Binh An Tran, Anne Bol, Daniel Labar, Bénédicte F. Jordan, Julie Magat, Lionel Mignion, Vincent Grégoire, Bernard Gallez · 2012 · Radiotherapy and Oncology
22. Discovery of pre-therapy 2-deoxy-2-18F-fluoro-D-glucose positron emission tomography-based radiomics classifiers of survival outcome in non-small-cell lung cancer patients
    Mubarik Arshad, Andrew Thornton, Haonan Lu, Henry Tam, Kathryn L. Wallitt, Nicola Rodgers, Andrew Frederick Scarsbrook, Garry M. McDermott, Gary Cook, David Landau et al. · 2018 · European Journal of Nuclear Medicine and Molecular Imaging
23. Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities
    Venessa T. Chin, Adnan M. Nagrial, Angela S. Y. Chou, Andrew Victor Biankin, Anthony James Gill, Paul Timpson, Marina Pajic · 2015 · Expert Reviews in Molecular Medicine
24. Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides
    Muriel Bonnet, Cho Rong Hong, Way Wua Wong, Lydia P. Liew, Avik Shome, Jingli Wang, Yongchuan Gu, Ralph J. Stevenson, Wen Qi, Robert F. Anderson et al. · 2017 · Journal of Medicinal Chemistry
25. Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: Possible implications for radiotherapy treatment planning strategies
    Vikram Rao Bollineni, Michel J. B. Koole, Jan Pruim, Charlotte L. Brouwer, Erwin M. Wiegman, Harry J.M. Groen, Renske Vlasman, Gyorgy Bela Halmos, Sjoukje F. Oosting, Johannes Albertus Langendijk et al. · 2014 · Radiotherapy and Oncology
26. Modeling the effect of intratumoral heterogeneity of radiosensitivity on tumor response over the course of fractionated radiation therapy
    Juan Carlos López Alfonso, Lawrence B Berk · 2019 · Radiation Oncology
27. Developing oxygen-enhanced magnetic resonance imaging as a prognostic biomarker of radiation response
    Derek A. White, Zhang Zhang, Li Li, Jeni Gerberich, Strahinja Stojadinović, Peter Peschke, Ralph P. Mason · 2016 · Cancer Letters
28. Dose prescription and optimisation based on tumour hypoxia
    Iuliana Toma-Daşu, Alexandru Daşu, Anders Brahme · 2009 · Acta Oncologica
29. Exploratory Study of the Prognostic Value of Microenvironmental Parameters During Fractionated Irradiation in Human Squamous Cell Carcinoma Xenografts
    Ala Yaromina, Theresa Kroeber, Andreas Meinzer, Simon Boeke, Howard D. Thames, Michael A. Baumann, Daniel Zips · 2011 · International Journal of Radiation Oncology*Biology*Physics
30. Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer
    Quynh‐Thu Le, Richard Fisher, Kelly Smith Oliner, Richard J. Young, Hongbin Cao, Christina S. Kong, Edward Elliot Graves, Rodney J. Hicks, Grant A. McArthur, Lester Peters et al. · 2012 · Clinical Cancer Research
31. Validation of a 15-gene hypoxia classifier in head and neck cancer for prospective use in clinical trials
    Kasper Toustrup, Brita Singers Sørensen, Mohamed A. Hassan Metwally, Trine Tramm, Lise Saksø Mortensen, Jens Overgaard, Jan Alsner · 2016 · Acta Oncologica
32. Resolution in PET hypoxia imaging: Voxel size matters
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33. Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck
    Hanneke Stegeman, Johannes H.A.M. Kaanders, Deric L. Wheeler, Albert J. van der Kogel, Marieke MG Verheijen, Stijn J.H. Waaijer, Mari Iida, Reidar A. Grenman, Paul N. Span, Johan Bussink · 2012 · BMC Cancer
34. The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation
    George J. Cerniglia, Souvik Dey, Shannon M. Gallagher‐Colombo, Natalie A. Daurio, Stephen W. Tuttle, Theresa M. Busch, Alexander Lin, Ramon C. Sun, Tatiana V. Esipova, Sergei A. Vinogradov et al. · 2015 · Molecular Cancer Therapeutics
35. Radioresistance of Brain Tumors
    Kevin D. Kelley, Jonathan Petrus Sandberg Knisely, Marc H. Symons, Rosamaria Ruggieri · 2016 · Cancers
36. Improving the Radiosensitivity of Radioresistant and Hypoxic Glioblastoma
    Jason P. Sheehan, Mark Edwin Shaffrey, Brinda Gupta, James Mitchell Larner, Jeremy N. Rich, Deric M. Park · 2010 · Future Oncology
37. Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes
    Peter Wardman · 2018 · British Journal of Radiology
38. Targeting antioxidant enzymes as a radiosensitizing strategy
    Heng Jiang, Hui Wang, Mark De Ridder · 2018 · Cancer Letters
39. The importance of haemoglobin level and effect of transfusion in HNSCC patients treated with radiotherapy – Results from the randomized DAHANCA 5 study
    Camilla Molich Hoff, Hanne Sand Hansen, Marie Overgaard, Cai Grau, Jørgen Johansen, Jens Bentzen, Jens Overgaard · 2010 · Radiotherapy and Oncology
40. Neoadjuvant treatment of esophageal cancer
    Nicholas Paul Campbell · 2010 · World Journal of Gastroenterology
41. Phase II Study of Tirapazamine, Cisplatin, and Etoposide and Concurrent Thoracic Radiotherapy for Limited-Stage Small-Cell Lung Cancer: SWOG 0222
    Quynh‐Thu Le, James Moon, Mary Weber Redman, Stephen K. Williamson, Primo N. Lara, Zelanna Goldberg, Laurie E. Gaspar, John J. Crowley, Dennis Frederic Moore, David R. Gandara · 2009 · Journal of Clinical Oncology
42. Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors
    Franziska Eckert, Kerstin Zwirner, Simon Boeke, Daniela Thorwarth, Daniel Zips, Stephan M. Huber · 2019 · Frontiers in Immunology
43. EPR Oxygen Images Predict Tumor Control by a 50% Tumor Control Radiation Dose
    Martyna Elas, Jessica M. Magwood, Brandi Butler, Chanel Li, Rona Wardak, Rebekah DeVries, Eugene D. Barth, Boris Epel, Samuel M. Rubinstein, Charles A. Pelizzari et al. · 2013 · Cancer Research
44. Albumin-Templated Bi 2 Se 3 –MnO 2 Nanocomposites with Promoted Catalase-Like Activity for Enhanced Radiotherapy of Cancer
    Yuzhu Yao, Puze Li, Junkai He, Dongdong Wang, Jun Hu, Xiangliang Yang · 2021 · ACS Applied Materials & Interfaces
45. Carbon Ions for Hypoxic Tumors: Are We Making the Most of Them?
    Olga Sokol, Marco Durante · 2023 · Cancers
46. Tumor oxygenation and cancer therapy—then and now
    Veronica S. Hughes, Jennifer M. Wiggins, Dietmar W. Siemann · 2018 · British Journal of Radiology
47. Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments
    Kenneth K.W. To, Winnie Fong, Christy W.S. Tong, Mingxia Wu, Wei Yan, William Chi Shing Cho · 2019 · Expert Opinion on Drug Discovery
48. New ways to image and target tumour hypoxia and its molecular responses
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49. Paradigm Shift in Radiation Biology/Radiation Oncology—Exploitation of the “H2O2 Effect” for Radiotherapy Using Low-LET (Linear Energy Transfer) Radiation such as X-rays and High-Energy Electrons
    Yasuhiro Ogawa · 2016 · Cancers
50. Peroxiredoxins in Cancer and Response to Radiation Therapies
    Tom E. Forshaw, Reetta J. Holmila, Kimberly Johnson Nelson, Joshua E. Lewis, Melissa Lambeth Kemp, Allen W. Tsang, Leslie B. Poole, W. Todd Lowther, Cristina M. Furdui · 2019 · Antioxidants
51. Hyperbaric oxygenation for tumour sensitisation to radiotherapy
    Michael Bennett, John Feldmeier, Robert Smee, Christopher Milross · 2018 · Cochrane Database of Systematic Reviews
52. Relationship Between Low Hemoglobin Levels and Outcomes After Treatment With Radiation or Chemoradiation in Patients With Cervical Cancer: Has the Impact of Anemia Been Overstated?
    Andrew Justin Bishop, Pamela K. Allen, Ann H. Klopp, Larissa Alejandra Meyer, Patricia J. Eifel · 2014 · International Journal of Radiation Oncology*Biology*Physics
53. Molecular imaging of hypoxia in non-small-cell lung cancer
    Connie Yip, Philip J. Blower, Vicky Goh, David Landau, Gary Cook · 2015 · European Journal of Nuclear Medicine and Molecular Imaging
54. The Impact of the Myeloid Response to Radiation Therapy
    Michael J. Gough, Kristina Hoot Young, Marka R. Crittenden · 2013 · Clinical and Developmental Immunology
55. Does transfusion improve the outcome for HNSCC patients treated with radiotherapy? – Results from the randomized DAHANCA 5 and 7 trials
    Camilla Molich Hoff, P. Lassen, Jesper Grau Eriksen, Hanne Sand Hansen, Lena Specht, Marie Overgaard, Cai Grau, Jørgen Johansen, Jens Bentzen, Lisbeth Juhler Andersen et al. · 2011 · Acta Oncologica
56. Modelling the interplay between hypoxia and proliferation in radiotherapy tumour response
    Jeho Jeong, Kooresh Isaac Shoghi, Joseph O. Deasy · 2013 · Physics in Medicine and Biology
57. Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma
    Bouchra Tawk, Christian Schwager, Oliver Johannes Deffaa, Gerhard Dyckhoff, Rolf Warta, Annett Linge, Mechthild Krause, Wilko Weichert, Michael A. Baumann, Christel C. Herold‐Mende et al. · 2015 · Radiotherapy and Oncology
58. On the Path to Seeking Novel Radiosensitizers
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59. Hypoxia in cervical cancer: from biology to imaging
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60. Radiotherapy resistance: identifying universal biomarkers for various human cancers
    Irina Larionova, Militsa A. Rakina, Elena E. Ivanyuk, Yu. M. Trushchuk, А. Л. Чернышова, Evgeny V. Denisov · 2022 · Journal of Cancer Research and Clinical Oncology
61. PET hypoxia imaging with FAZA: reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice
    Morten Busk, Lise Saksø Mortensen, Marianne Nordsmark, Jens Overgaard, Steen Jakobsen, K. Hansen, J. Theil, Jesper Folsted Kallehauge, Filippo P. D’Andrea, Torben Steiniche et al. · 2012 · European Journal of Nuclear Medicine and Molecular Imaging
62. Development and Validation of a Gene Signature for Patients with Head and Neck Carcinomas Treated by Postoperative Radio(chemo)therapy
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63. Emerging Magnetic Resonance Imaging Technologies for Radiation Therapy Planning and Response Assessment
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64. Detection of Hypoxia With 18F-Fluoromisonidazole (18F-FMISO) PET/CT in Suspected or Proven Pancreatic Cancer
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65. The Inflammatory Tissue Microenvironment in IBD
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66. Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
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67. Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications
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68. Molecular Targets for Tumor Radiosensitization
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69. Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study
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70. Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia
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71. Oxygen microbubbles improve radiotherapy tumor control in a rat fibrosarcoma model – A preliminary study
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72. HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism
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73. The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia
    Marianne Koritzinsky, Bradly G. Wouters · 2013 · Seminars in Radiation Oncology
74. 2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche
    Naoyoshi Koike, Ryuichi Kota, Yoshiko Naito, Noriyo Hayakawa, Tomomi Matsuura, Takako Hishiki, Nobuyuki Onishi, Junichi Fukada, Makoto Suematsu, Naoyuki Shigematsu et al. · 2020 · Communications Biology
75. Hyperbaric oxygenation for tumour sensitisation to radiotherapy
    Michael Bennett, John Feldmeier, Robert Smee, Christopher Milross · 2005 · Cochrane Database of Systematic Reviews
76. Hypoxia in Head and Neck Squamous Cell Carcinoma
    Zeng-Hong Li, Wei Gao, Jimmy Yu Wai Chan, Wai-Kuen Ho, Thian‐Sze Wong · 2012 · ISRN Otolaryngology
77. Milestones in the Use of Combined-Modality Radiation Therapy and Chemotherapy
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78. Overexpression of HIF1α and CAXI predicts poor outcome in early-stage triple negative breast cancer
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79. Hypoxia gene expression signatures as predictive biomarkers for personalising radiotherapy
    Lingjian Yang, Catharine West · 2018 · British Journal of Radiology
80. Hypoxia and its therapeutic possibilities in paediatric cancers
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81. Radiosensitising agents for the radiotherapy of cancer: advances in traditional and hypoxia targeted radiosensitisers
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82. Biomolecule-protected gold nanoclusters: synthesis and biomedical applications
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83. Improving chemoradiation efficacy by PI3-K/AKT inhibition
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84. Clinical trials targeting hypoxia
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85. Epigenetics in radiotherapy: Where are we heading?
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86. Phase I study of a new radiosensitizer containing hydrogen peroxide and sodium hyaluronate for topical tumor injection: A new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II)
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87. Cell Growth in Aggregates Determines Gene Expression, Proliferation, Survival, Chemoresistance, and Sensitivity to Immune Effectors in Follicular Lymphoma
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88. Synthesis of Mitochondria-Anchored Nitroimidazoles with a Versatile NIR Fluorophore for Hypoxic Tumor-Targeting Imaging and Chemoradiotherapy
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89. In Situ Formed Z-Scheme Graphdiyne Heterojunction Realizes NIR-Photocatalytic Oxygen Evolution and Selective Radiosensitization for Hypoxic Tumors
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90. Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption
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91. Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence
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92. Photothermal photodynamic therapy and enhanced radiotherapy of targeting copolymer-coated liquid metal nanoparticles on liver cancer
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93. Impact of hypoxia on cervical cancer outcomes
    Anubhav Datta, Catharine West, James P.B. O’Connor, Ananya Choudhury, Peter Hoskin · 2021 · International Journal of Gynecological Cancer
94. Essential Role of DNA Base Excision Repair on Survival in an Acidic Tumor Microenvironment
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95. Liposome‐Encapsulated Hemoglobin Ameliorates Tumor Hypoxia and Enhances Radiation Therapy to Suppress Tumor Growth in Mice
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96. Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: A preclinical study
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97. IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma
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98. The impact of preoperative anaemia and anaemic subtype on patient outcome in colorectal cancer
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99. What will radiation oncology look like in 2050? A look at a changing professional landscape in Europe and beyond
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100. First Comparison between [18f]-FMISO and [18f]-Faza for Preoperative Pet Imaging of Hypoxia in Lung Cancer
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