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Cited by 959

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

MicroRNAs in Cancer: Small Molecules With a Huge Impact

Open access
Iorio, Marilena V., Croce, Carlo M.·2009·Journal of Clinical Oncology

Abstract

Every cellular process is likely to be regulated by microRNAs, and an aberrant microRNA expression signature is a hallmark of several diseases, including cancer. MicroRNA expression profiling has indeed provided evidence of the association of these tiny molecules with tumor development and progression. An increasing number of studies have then demonstrated that microRNAs can function as potential oncogenes or oncosuppressor genes, depending on the cellular context and on the target genes they regulate. Here we review our current knowledge about the involvement of microRNAs in cancer and their potential as diagnostic, prognostic, and therapeutic tools.

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Crossref · 10.1200/jco.2009.24.0317

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Metadata

Authors
Iorio, M. V., & Croce, C. M.
Venue
Journal of Clinical Oncology
Published
2009-12-01
Volume
27
Issue
34
Pages
5848-5856
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
OpenAlex
W2047146433
Cited by
959
References
15
FWCI
23.41
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: MicroRNAs in Cancer: Small Molecules With a Huge Impact. https://app.cochat.ai/papers/10.1200/jco.2009.24.0317
The paper
Iorio, M. V., & Croce, C. M. (2009). MicroRNAs in Cancer: Small Molecules With a Huge Impact. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2009.24.0317

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.