The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Advances in Immuno–Positron Emission Tomography: Antibodies for Molecular Imaging in Oncology
Open accessAbstract
Identification of cancer cell–surface biomarkers and advances in antibody engineering have led to a sharp increase in the development of therapeutic antibodies. These same advances have led to a new generation of radiolabeled antibodies and antibody fragments that can be used as cancer-specific imaging agents, allowing quantitative imaging of cell-surface protein expression in vivo. Immuno–positron emission tomography (immunoPET) imaging with intact antibodies has shown success clinically in diagnosing and staging cancer. Engineered antibody fragments, such as diabodies, minibodies, and single-chain Fv (scFv) –Fc, have been successfully employed for immunoPET imaging of cancer cell–surface biomarkers in preclinical models and are poised to bring same-day imaging into clinical development. ImmunoPET can potentially provide a noninvasive approach for obtaining target-specific information useful for titrating doses for radioimmunotherapy, for patient risk stratification and selection of targeted therapies, for evaluating response to therapy, and for predicting adverse effects, thus contributing to the ongoing development of personalized cancer treatment.
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FcRn: the neonatal Fc receptor comes of age
Roopenian, D. C., & Akilesh, S. (2007) · Nature Reviews Immunology · doi:10.1038/nri2155 · Cited by 2,346
Vogel, C. L., Cobleigh, M. A., Tripathy, D., Gutheil, J. C., Harris, L. N., Fehrenbacher, L., Slamon, D. J., Murphy, M., Novotny, W. F., Burchmore, M., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.20.3.719 · Cited by 1,860
Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
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Metabolic positron emission tomography imaging in cancer detection and therapy response
Zhu, A., Lee, D., & Shim, H. (2011) · Seminars in Oncology · doi:10.1053/j.seminoncol.2010.11.012 · Cited by 368 · cited 1×
“tic efficacy shortly after initiation of therapy in many cancers.(5) However, not all tumors show high [(18)F]FDG uptake, and high glucose use is not a pro-”
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An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy
Tavaré, R., Escuin-Ordinas, H., Mok, S., McCracken, M. N., Zettlitz, K. A., Salazar, F. B., Witte, O. N., Ribas, A., & Wu, A. M. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-1707 · Cited by 320
Self-citationMolecular imaging of the tumor microenvironment
Zhou, Z., & Lu, Z.-R. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.07.012 · Cited by 253
Pandit-Taskar, N., Postow, M. A., Hellmann, M. D., Harding, J. J., Barker, C. A., O’Donoghue, J. A., Ziolkowska, M., Ruan, S., Lyashchenko, S. K., Tsai, F., et al. (2020) · Journal of Nuclear Medicine · doi:10.2967/jnumed.119.229781 · Cited by 257
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Metadata
- Authors
- Knowles, S. M., & Wu, A. M.
- Venue
- Journal of Clinical Oncology
- Published
- 2012-11-01
- Volume
- 30
- Issue
- 31
- Pages
- 3884-3892
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2168506617
- Cited by
- 209
- References
- 5
- FWCI
- 13.13
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
