The DOI matches its Crossref record; 51 of the 53 references it cites were found in a registry or an index.
Trajectories of Psychological Distress in Adolescent and Young Adult Patients With Cancer: A 1-Year Longitudinal Study
Abstract
Purpose: To examine prevalence and changes in symptoms of psychological distress over 1 year after initial cancer diagnosis in adolescent and young adult (AYA) patients with cancer. Sociodemographic and clinical predictors of changes in distress were examined. Patients and Methods: In this multisite, longitudinal, prospective study of an ethnically diverse sample, 215 patients age 14 to 39 years were assessed for psychological distress within the first 4 months of diagnosis and again 6 and 12 months later. Linear mixed models with random intercept and slope estimated changes in distress, as measured by the Brief Symptom Inventory-18 (BSI-18). Results: Within the first 4 months of diagnosis, 60 respondents (28%) had BSI-18 scores suggesting caseness for distress. On average, distress symptoms exceeded population norms at the time of diagnosis, dipped at the 6-month follow-up, but increased to a level exceeding population norms at the 12-month follow-up. A statistically significant decline in distress over 1 year was observed; however, the gradient of change was not clinically significant. Multivariate analyses revealed that the reduction in distress over time was primarily a function of being off treatment and involved in school or work. Notably, cancer type or severity was not associated with distress. Conclusion: Findings emphasize the importance of early psychosocial intervention for distress in AYAs as well as the need to manage treatment-related symptoms and facilitate AYAs' involvement in work or school to the extent possible. Continued research is needed to understand how distress relates to quality of life, functional outcomes, treatment, and symptom burden throughout the continuum of care.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“For many YA cancer survivors, the impact of treatment is significant and long-lasting, including difficult physical symptoms (e.g., pain, fatigue) [4–6], psychological distress [6–10], and an increased risk of long-term health problems (e.g., second cancers, early-onset cardiovascular disease) [11–13].”
From Improving symptom management for survivors of young adult cancer: rationale and study protocol for a pilot randomized controlled trial (2024) · cites this paper as [8]
In the citing paper
“Adolescents and young adults are most likely to experience depression, heightened anxiety, distress, and posttraumatic stress disorder in their first 12-24 months after completing treatment, which poses significant unmet mental health needs in the period after cancer treatment [2-4].”
In the citing paper
“In addition to this disproportionate disease burden, there are significant and unique psychosocial needs for adolescents and young adults diagnosed with cancer [2].”
Citations
Cites
1 retracted
Outcomes Assessment in Cancer: Measures, Methods and Applications
Theofilou, P. (2013) · Europe’s Journal of Psychology · doi:10.5964/ejop.v9i1.411 · Cited by 183
RetractedEmerging adulthood: A theory of development from the late teens through the twenties.
Arnett, J. J. (2000) · American Psychologist · doi:10.1037/0003-066x.55.5.469 · Cited by 16,843
Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence
Singer, J. D., & Willett, J. B. (2003) · doi:10.1093/acprof:oso/9780195152968.001.0001 · Cited by 10,647
(2010) · Cited by 7,034
Derogatis, L. R. (1982) · PsycTESTS Dataset · doi:10.1037/t00789-000 · Cited by 863
Meyer, T. J., & Mark, M. M. (1995) · Health Psychology · doi:10.1037/0278-6133.14.2.101 · Cited by 689
Zeltzer, L. K., Recklitis, C., Buchbinder, D., Zebrack, B., Casillas, J., Tsao, J. C. I., Lu, Q., & Krull, K. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.21.1433 · Cited by 660
Self-citationDerogatis, L. R. (2011) · PsycTESTS Dataset · doi:10.1037/t07502-000 · Cited by 656
Psychological, social, and behavioral issues for young adults with cancer
Zebrack, B. (2011) · Cancer · doi:10.1002/cncr.26056 · Cited by 512
Self-citationDistress Management Clinical Practice Guidelines in Oncology
(2003) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2003.0031 · Cited by 506
Ganz, P. A., Kwan, L., Stanton, A. L., Krupnick, J. L., Rowland, J. H., Meyerowitz, B. E., Bower, J. E., & Belin, T. R. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh060 · Cited by 505
Zeltzer, L. K., Lü, Q., Leisenring, W. M., Tsao, J. C. I., Recklitis, C. J., Armstrong, G. T., Mertens, A. C., Robison, L. L., & Ness, K. K. (2008) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-07-2541 · Cited by 465
Psychosocial care of adolescent and young adult patients with cancer and survivors
Zebrack, B., & Isaacson, S. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.39.5467 · Cited by 462 · cited 1×
“Cancer challenges AYAs’ abilities to deal with these developmental issues.(12) For instance, changes in physical”
BackgroundSelf-citationHolland, J. C., Andersen, B. L., BREITBART, W. S., Buchmann, L. O., Compas, B. E., Deshields, T. L., Shannon-Dudley, M., Fleishman, S. B., Fulcher, C. D., Greenberg, D. B., et al. (2013) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2013.0027 · Cited by 444
Royston, P. (2009) · The Stata Journal: Promoting communications on statistics and Stata · doi:10.1177/1536867x0900900308 · Cited by 428
Psychosocial concerns and interventions for cancer survivors
Stanton, A. L. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.8775 · Cited by 409 · cited 1×
“Indeed, studies indicate that psychosocial and quality-of-life outcomes are worse for patients 1 year after initial diagnosis(45-47) and that the end of treatment and transition to off-treatment survival are often fraught with distress.(48,49) Continued research is needed to understand how distress is related to quali…”
BackgroundPsychosocial and demographic predictors of quality of life in a large sample of cancer patients
Parker, P. A., Baile, W. F., de Moor, C., & Cohen, L. G. (2002) · Psycho-Oncology · doi:10.1002/pon.635 · Cited by 408
Zebrack, B., Zeltzer, L. K., Whitton, J. A., Mertens, A. C., Odom, L. F., Berkow, R. L., & Robison, L. L. (2002) · PEDIATRICS · doi:10.1542/peds.110.1.42 · Cited by 385
Self-citationJacobsen, P. B., & Jim, H. S. (2008) · CA: A Cancer Journal for Clinicians · doi:10.3322/ca.2008.0003 · Cited by 382
(2014) · Springer eBooks · doi:10.1007/978-94-007-0753-5_100334 · Cited by 376
Carlson, L. E., & Bultz, B. D. (2003) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(03)00514-2 · Cited by 351
Symptom Distress and Quality of Life in Patients with Advanced Chronic Obstructive Pulmonary Disease
Blinderman, C. D., Homel, P., Billings, J. A., Tennstedt, S. L., & Portenoy, R. K. (2009) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2008.07.006 · Cited by 316
Effects of psychological treatment on cancer patients: a critical review.
Trijsburg, R. W., van Knippenberg, F. C. E., & Rijpma, S. E. (1992) · Psychosomatic Medicine · doi:10.1097/00006842-199207000-00011 · Cited by 308
D'Agostino, N. M., Penney, A., & Zebrack, B. (2011) · Cancer · doi:10.1002/cncr.26043 · Cited by 289
Self-citationGraves, K. D. (2003) · Health Psychology · doi:10.1037/0278-6133.22.2.210 · Cited by 239
Recklitis, C. J., Parsons, S. K., Shih, M.-C., Mertens, A., Robison, L. L., & Zeltzer, L. (2006) · Psychological Assessment · doi:10.1037/1040-3590.18.1.22 · Cited by 209
Andersen, B. L., Farrar, W. B., Golden‐Kreutz, D. M., Emery, C. F., Glaser, R., Crespin, T. R., & Carson, W. E. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.03.005 · Cited by 200
Prevalence and Predictors of Posttraumatic Stress Disorder in Adult Survivors of Childhood Cancer
Stuber, M. L., Meeske, K., Krull, K. R., Leisenring, W. M., Stratton, K. L., Kazak, A. E., Huber, M., Zebrack, B., Uijtdehaage, S. H. J., Mertens, A. C., et al. (2010) · PEDIATRICS · doi:10.1542/peds.2009-2308 · Cited by 191
Self-citationCancer support groups: a critical review of empirical studies
Gottlieb, B. H., & Wachala, E. D. (2006) · Psycho-Oncology · doi:10.1002/pon.1078 · Cited by 185
ESSEN, L. V., LARSSON, G., ÖBERG, K., & SJÖDÉN, P. O. (2002) · European Journal of Cancer Care · doi:10.1046/j.1365-2354.2002.00293.x · Cited by 176
Psychosocial dimensions of cancer in adolescents and young adults
Evan, E. E., & Zeltzer, L. K. (2006) · Cancer · doi:10.1002/cncr.22107 · Cited by 163
The relationship between unmet needs and distress amongst young people with cancer
Dyson, G., Thompson, K., Palmer, S., Thomas, D. M., & Schofield, P. E. (2011) · Supportive Care in Cancer · doi:10.1007/s00520-010-1059-7 · Cited by 157
von Essén, L., Enskär, K., Kreuger, A., Larsson, B., & Sjödén, P. (2000) · Acta Paediatrica · doi:10.1111/j.1651-2227.2000.tb01221.x · Cited by 152
Perceptions of Distress Among Adolescents Recently Diagnosed With Cancer
Hedström, M., Ljungman, G., & von Essén, L. (2005) · Journal of Pediatric Hematology/Oncology · doi:10.1097/01.mph.0000151803.72219.ec · Cited by 146
Shim, E., Mehnert, A., Koyama, A., Cho, S.-J., Inui, H., Paik, N.-S., & Koch, U. (2006) · Breast Cancer Research and Treatment · doi:10.1007/s10549-006-9216-x · Cited by 126
Jörngården, A., Mattsson, E., & von Essén, L. (2007) · European Journal of Cancer · doi:10.1016/j.ejca.2007.05.031 · Cited by 120
Enskär, K., & von Essén, L. (2007) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2007.01.003 · Cited by 108
Bleyer, A. (2011) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2010.0005 · Cited by 101
Han, W. T., Collie, K., Koopman, C., Azarow, J., Classen, C. C., Morrow, G. R., Michel, B., Brennan-O'Neill, E., & Spiegel, D. (2004) · Psycho-Oncology · doi:10.1002/pon.852 · Cited by 99
Wu, E., Robison, L. L., Jenney, M. E. M., Rockwood, T. H., Feusner, J. H., Friedman, D. L., Kane, R. L., & Bhatia, R. (2006) · Pediatric Blood & Cancer · doi:10.1002/pbc.20874 · Cited by 87
Uncertainty, Posttraumatic Stress, and Health Behavior in Young Adult Childhood Cancer Survivors
Santacroce, S. J., & Lee, Y. (2006) · Nursing Research · doi:10.1097/00006199-200607000-00006 · Cited by 57
Gordon, L. G., Beesley, V. L., & Scuffham, P. (2011) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/j.1743-7563.2011.01395.x · Cited by 55
Health profiles of younger and older breast cancer survivors
Stava, C. J., López, A., & Vassilopoulou‐Sellin, R. (2006) · Cancer · doi:10.1002/cncr.22200 · Cited by 49
Quality of Life Among Adolescents With Cancer
Ward-Smith, P. A., Hamlin, J. S., Bartholomew, J., & Stegenga, K. (2007) · Journal of Pediatric Oncology Nursing · doi:10.1177/1043454207299656 · Cited by 40
Breast cancer in the life course : women's experiences
Oktay, J. S., & Walter, C. A. (1991) · Springer eBooks · Cited by 31
Cwikel, J., Behar, L. C., & Rabson-Hare, J. (2000) · Research on Social Work Practice · doi:10.1177/15527581-00010001-02 · Cited by 31
Baker, F., Denniston, M. M., Hann, D. M., Gesme, D. H., Reding, D. J., Flynn, T. J., & Kennedy, J. (2007) · Journal of Psychosocial Oncology · doi:10.1300/j077v25n02_01 · Cited by 22
The role of radiation therapy in the treatment of colorectal cancer
Farniok, K. E., & Levitt, S. H. (1994) · Cancer · doi:10.1002/1097-0142(19941001)74:7+ · Cited by 17
Statistical issues in the application of cancer outcome measures
Sloan, J. A. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511545856.018 · Cited by 7
VON ESSEN L PERCEPTIONS OF DISTRESS AMONG ADOLESCENTS RECENTLY DIAGNOSED WITH CANCER
Hedström, M., & Ljungman, G. (2005) · Cited by 5
The prevalence of psychological distress by cancer site
Zabora, J., BrintzenhofeSzoc, K., Curbow, B., Hooker, C., & Piantadosi, S. (2001) · Psycho-Oncology · doi:10.1002/1099-1611(200101/02)10:1
Research works printed but not linked: 2
- Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults With Cancer—A Report of the Adolescent and Young Adult Oncology Program Review Group 2006 National Cancer Institute Bethesda, MD National Institutes of Health
- SEER Cancer Statistics Review 1975– 2008,2010 National Cancer Institute
Cited by
Sorted by citations
Survivors of childhood and adolescent cancer: life-long risks and responsibilities
Robison, L. L., & Hudson, M. M. (2013) · Nature reviews. Cancer · doi:10.1038/nrc3634 · Cited by 857
Nass, S. J., Beaupin, L. K., Demark-Wahnefried, W., Fasciano, K., Ganz, P. A., Hayes-Lattin, B., Hudson, M. M., Nevidjon, B., Oeffinger, K. C., Rechis, R., et al. (2015) · The Oncologist · doi:10.1634/theoncologist.2014-0265 · Cited by 311
Self-citationAdolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology
Coccia, P. F., Pappo, A. S., Beaupin, L., Borges, V. F., Borinstein, S. C., Chugh, R., Dinner, S., Folbrecht, J., Frazier, A. L., Goldsby, R., et al. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.0001 · Cited by 295
Quality of life in adolescent and young adult cancer patients: a systematic review of the literature
Quinn, G. P., Gonçalves, V., Sehovic, I., Bowman, M., & Reed, D. R. (2015) · Patient Related Outcome Measures · doi:10.2147/prom.s51658 · Cited by 289
Greer, S., Ramo, D., Chang, Y.-J., Fu, M., Moskowitz, J., & Haritatos, J. (2019) · JMIR mHealth and uHealth · doi:10.2196/15018 · Cited by 265
Metadata
- Authors
- Kwak, M., Zebrack, B. J., Meeske, K. A., Embry, L., Aguilar, C., Block, R., Hayes-Lattin, B., Li, Y., Butler, M., & Cole, S.
- Affiliations
- University of Southern California (US)
- Minyoung Kwak and Brad J. Zebrack, University of Michigan School of Social Work; Yun Li, University of Michigan and University of Michigan Comprehensive Cancer Center, Ann Arbor; Melissa Butler, University of Michigan, Dearborn, MI; Kathleen A. Meeske, University of Southern California, Children's Hospital Los Angeles, Los Angeles; Steven Cole, HopeLab Foundation, Redwood City, CA; Leanne Embry and Christine Aguilar, University of Texas Health Science Center at San Antonio, San Antonio, TX; Rebecca Block...
- Venue
- Journal of Clinical Oncology
- Published
- 2013-06-10
- Volume
- 31
- Issue
- 17
- Pages
- 2160-2166
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2106939934
- Cited by
- 234
- References
- 53
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 21 · 2023: 21 · 2022: 19 · 2021: 21 · 2020: 19 · 2019: 28 · 2018: 24 · 2017: 22 · 2016: 17 · 2015: 11 · 2014: 13 · 2013: 2
- FWCI
- 13.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Clinical Psychology › Family Support in Illness
- Keywords
- psychological distress, adolescent and young adult cancer, cancer survivors, Brief Symptom Inventory-18, predictors of distress, treatment discontinuation, psychosocial interventions, quality of life
- MeSH terms
- Adolescent, Adult, Female, Humans, Longitudinal Studies, Male, Neoplasms, Prospective Studies, Quality of Life, Stress, Psychological, Prevalence, Survivors, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
