Toxicant-Receptor Interactions: Modulations of signal transduction and gene expression
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The aryl hydrocarbon receptor (AhR) is a basic helix-loop-helix (bHLH), PAS-containing transcription factor present in numerous species and tissues that activates gene expression in a ligand-dependent manner.
“The aryl hydrocarbon receptor (AhR) 1 is a basic helix-loop-helix (bHLH), PAS- (Per-ArntSim-) containing transcription factor which is present in numerous species and tissues and activates gene expression in a ligand-dependent manner (1-3).”
From Structural and Functional Characterization of the Aryl Hydrocarbon Receptor Ligand Binding Domain by Homology Modeling and Mutational Analysis (2007) · cites this paper as [2]
Cited by
Sorted by citations
Denison, M. S., & Nagy, S. R. (2003) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.135828 · Cited by 1,895 · see citing works
Inhibitory Aryl Hydrocarbon Receptor−Estrogen Receptor α Cross-Talk and Mechanisms of Action
Safe, S. H., & Wormke, M. (2003) · Chemical Research in Toxicology · doi:10.1021/tx034036r · Cited by 348 · see citing works
Behnisch, P., Hosoe, K., & Sakai, S.-I. (2001) · Environment International · doi:10.1016/s0160-4120(01)00028-9 · Cited by 254 · see citing works
Villeneuve, D. L., Khim, J. S., Kannan, K., et al. (2002) · Environmental Toxicology · doi:10.1002/tox.10041 · Cited by 224 · see citing works
Carlson, D. B., & Perdew, G. H. (2002) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.10051 · Cited by 184 · see citing works
Hilscherová, K., Machala, M., Kannan, K., Blankenship, A. L., & Giesy, J. P. (2000) · Environmental Science and Pollution Research · doi:10.1065/espr2000.02.017 · Cited by 168 · see citing works
Pandini, A., Denison, M. S., Song, Y., Soshilov, A. A., & Bonati, L. (2007) · Biochemistry · doi:10.1021/bi061460t · Cited by 160 · see citing works
Nguyen, T. A., Hoivik, D. J., Lee, J., & Safe, S. H. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1282 · Cited by 145 · see citing works
Giesy, J. P., Hilscherová, K., Jones, P. D., Kannan, K., & Machala, M. (2002) · Marine Pollution Bulletin · doi:10.1016/s0025-326x(02)00097-8 · Cited by 136 · see citing works
Activation of the Ah Receptor by Extracts of Dietary Herbal Supplements, Vegetables, and Fruits
Jeuken, A., Keser, B., Khan, E. M., Brouwer, A., Koeman, J. H., & Denison, M. S. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf030252u · Cited by 130 · see citing works
Kumar, S., Sajwan, K. S., Richardson, J. P., et al. (2008) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2007.08.011 · Cited by 119 · see citing works
Khim, J. S., Villeneuve, D. L., Kannan, K., et al. (1999) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620181107 · Cited by 117 · see citing works
Comparison of recombinant cell bioassays for the detection of Ah receptor agonists
Han, D., Nagy, S. R., & Denison, M. S. (2004) · BioFactors · doi:10.1002/biof.5520200102 · Cited by 114 · see citing works
Petrulis, J. R., Hord, N. G., & Perdew, G. H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006873200 · Cited by 111 · see citing works
New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability
Motto, I., Bordogna, A., Soshilov, A. A., Denison, M. S., & Bonati, L. (2011) · Journal of Chemical Information and Modeling · doi:10.1021/ci2001617 · Cited by 80 · see citing works
Khim, J. S., Villeneuve, D. L., Kannan, K., et al. (1999) · Environmental Science & Technology · doi:10.1021/es990449w · Cited by 80 · see citing works
Effects of atrazine and endosulfan sulphate on the ecdysteroid system of Daphnia magna
Palma, P., Palma, V. L., Matos, C., et al. (2008) · Chemosphere · doi:10.1016/j.chemosphere.2008.10.021 · Cited by 77 · see citing works
Jiang, W., Welty, S. E., Couroucli, X. I., et al. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.059766 · Cited by 69 · see citing works
Koh, C., Khim, J. S., Villeneuve, D. L., et al. (2005) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2005.03.005 · Cited by 59 · see citing works
Interaction between the aryl hydrocarbon receptor and its antagonists, flavonoids
Fukuda, I., Mukai, R., Kawase, M., Yoshida, K., & Ashida, H. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.05.199 · Cited by 58 · see citing works
Loughlin, C. M., Canosa, I. S., Silveyra, G. R., et al. (2016) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2016.05.009 · Cited by 55 · see citing works
Chloropicrin dechlorination in relation to toxic action
Sparks, S. E., Quistad, G. B., Li, W., & Casida, J. E. (2000) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/(sici)1099-0461(2000)14:1 · Cited by 28 · see citing works
Endocrine‐disrupting chemicals in a source water
Roefer, P., Snyder, S. A., Zegers, R. E., et al. (2000) · American Water Works Association · doi:10.1002/j.1551-8833.2000.tb08992.x · Cited by 51 · see citing works
Heuvel, J. P. V., Kreder, D. E., Belda, B. J., Hannon, D. B., Nugent, C. A., Burns, K. A., & Taylor, M. J. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00015-2 · Cited by 47 · see citing works
Nagy, S. R., Liu, G., Lam, K. S., & Denison, M. S. (2001) · Biochemistry · doi:10.1021/bi011373v · Cited by 41 · see citing works
Kannan, K., Villeneuve, D. L., Yamashita, N., et al. (2000) · Environmental Science & Technology · doi:10.1021/es001044a · Cited by 41 · see citing works
Silveyra, G. R., Silveyra, P., Vatnick, I., et al. (2018) · Aquatic Toxicology · doi:10.1016/j.aquatox.2018.02.017 · Cited by 37 · see citing works
Moorthy, B. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39072-x · Cited by 37 · see citing works
Attenuation of Hyperoxic Lung Injury by the CYP1A Inducer β–Naphthoflavone
Sinha, A., Muthiah, K., Jiang, W., et al. (2005) · Toxicological Sciences · doi:10.1093/toxsci/kfi226 · Cited by 36 · see citing works
“Induction of CYP1A1 by polycyclic aromatic hydrocarbons (PAHs) have been extensively studied (Denison and Helferich, 1998; Nebert et al., 2004; Shimada and Fujii-Kuriyama, 2004; Whitlock, 1999).”
BackgroundThe NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health
Landrigan, P. J., Wright, R. O., Cordero, J. F., et al. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1409247 · Cited by 35 · see citing works
Effects of atrazine on ovarian growth, in the estuarine crab Neohelice granulata
Silveyra, G. R., Canosa, I. S., Rodríguez, E. M., et al. (2016) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2016.10.011 · Cited by 34 · see citing works
Letcher, R. J., Sanderson, J. T., Bokkers, A., et al. (2005) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2005.03.013 · Cited by 34 · see citing works
Villeneuve, D. L., Villalobos, S. A., Keith, T. L., et al. (2002) · Chemosphere · doi:10.1016/s0045-6535(01)00212-0 · Cited by 34 · see citing works
AhR-active compounds in sediments of the Haihe and Dagu Rivers, China
Song, M., Jiang, Q., Xu, Y., Liu, H., Lam, P. K. S., O’Toole, D. K., Zhang, Q., Giesy, J. P., & Jiang, G. (2005) · Chemosphere · doi:10.1016/j.chemosphere.2005.08.065 · Cited by 31 · see citing works
Smith, K. J., Boyer, J. A., Muku, G. E., Murray, I. A., Gowda, K., Desai, D. H., Amin, S., Glick, A. B., & Perdew, G. H. (2017) · Toxicological Sciences · doi:10.1093/toxsci/kfx160 · Cited by 30 · see citing works
Aryl hydrocarbon receptor-mediated posttranscriptional regulation of IL-1β
Henley, D. V., Bellone, C. J., Williams, D. A., Ruh, T. S., & Ruh, M. F. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2003.11.022 · Cited by 29 · see citing works
Park, Y. K., Fukuda, I., Ashida, H., et al. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf058111a · Cited by 29 · see citing works
Interaction of diuron and related substituted phenylureas with the Ah receptor pathway
Zhao, B., Baston, D. S., Hammock, B. D., & Denison, M. S. (2006) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.20126 · Cited by 28 · see citing works
Ziccardi, M. H., Gardner, I. A., & Denison, M. S. (2002) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620211004 · Cited by 28 · see citing works
Koh, C., Khim, J. S., Villeneuve, D. L., et al. (2005) · Environmental Pollution · doi:10.1016/j.envpol.2005.09.006 · Cited by 26 · see citing works
Hecker, M., & Giesy, J. P. (2011) · The handbook of environmental chemistry · doi:10.1007/978-3-642-18384-3_12 · Cited by 25 · see citing works
Fukuda, I., Nishiumi, S., Yabushita, Y., Mukai, R., Kodoi, R., Hashizume, K., Mizuno, M., Hatanaka, Y., & Ashida, H. (2004) · Journal of Immunological Methods · doi:10.1016/j.jim.2004.02.003 · Cited by 22 · see citing works
Alvarez, N., Avigliano, L., Loughlin, C. M., et al. (2015) · Regional Studies in Marine Science · doi:10.1016/j.rsma.2014.12.001 · Cited by 18 · see citing works
Fukuda, I., Kaneko, A., Nishiumi, S., Kawase, M., Nishikiori, R., Fujitake, N., & Ashida, H. (2009) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2008.10.008 · Cited by 19 · see citing works
Fukuda, I., TSUTSUI, M., Sakane, I., et al. (2009) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.80868 · Cited by 15 · see citing works
Application of the luciferase cell culture bioassay for the detection of refined petroleum products
Ziccardi, M. H., Gardner, I. A., Mazet, J. A. K., et al. (2002) · Marine Pollution Bulletin · doi:10.1016/s0025-326x(02)00128-5 · Cited by 13 · see citing works
Rajnarayanan, R. V., Rowley, C. W., Hopkins, N. E., et al. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010563+ · Cited by 10 · see citing works
Hodek, P. (2012) · doi:10.1002/9783527630905.ch20 · Cited by 8 · see citing works
Rude, C. I., Tidwell, L. G., Tilton, S. C., et al. (2023) · Toxics · doi:10.3390/toxics11030201 · Cited by 7 · see citing works
Specificity of nuclear protein binding to a CYP1A1 negative regulatory element
Nagy, S. R., & Denison, M. S. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00945-2 · Cited by 4 · see citing works
Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons
Hammock, B. D., Sanborn, J. R., Sugawara, Y., et al. (2002) · CRC Press eBooks · doi:10.1201/9781420032208.ch33 · Cited by 2 · see citing works
Philp, R. B. (2013) · CRC Press eBooks · doi:10.1201/b14230-13
Xenobiotic Receptor-Mediated Carcinogenesis
Heuvel, J. P. V. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.95694-0
- Halogenated Hydrocarbons and Halogenated Aromatic Hydrocarbons
Philp, R. B. (2013) · CRC Press eBooks · doi:10.1201/b14230-7
- Environmental Hormone Disrupters
Philp, R. B. (2013) · CRC Press eBooks · doi:10.1201/b14230-14
Philp, R. B. (2013) · CRC Press eBooks · doi:10.1201/b14230-6
Halogenated hydrocarbons and halogenated aromatic hydrocarbons
(2001) · CRC Press eBooks · doi:10.1201/9781420032376.ch5
Environmental hormone disrupters
(2001) · CRC Press eBooks · doi:10.1201/9781420032376.ch12
- Venue
- CRC Press eBooks
- Publisher
- CRC Press
- Published
- 1998-08-10
- OpenAlex
- W2885678563
- Cited by
- 58
- References
- 0
- Citations by year
- 2023: 1 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 2 · 2013: 4 · 2012: 1
- Type
- reference entry
- Language
- en
- Open access
- closed
- Locations
- CRC Press eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Interaction Studies and Fluorescence Analysis
- Keywords
- receptors, toxicants
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
