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Cited by 403

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

The Processes of Scientific Discovery: The Strategy of Experimentation

Open access
Kulkarni, Deepak, Simon, Herbert A.·1988·Cognitive Science

Abstract

Hans Krebs' discovery, in 1932, of the urea cycle was a major event in biochemistry. This article describes a program, KEKADA, which models the heuristics Hans Krebs used in this discovery. KEKADA reacts to surprises, formulates explanations, and carries out experiments in the same manner as the evidence in the form of laboratory notebooks and interviews indicates Hans Krebs did. Furthermore, we answer a number of questions about the nature of the heuristics used by Krebs, in particular: How domain‐specific are the heuristics? To what extent are they idiosyncratic to Krebs? To what extent do they represent general strategies of problem‐solving search? The relative generality of KEKADA allows us to view the control structure of KEKADA and its domain‐independent heuristics as a model of scientific experimentation that should apply over a broad domain.

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Metadata

Authors
Kulkarni, D., & Simon, H. A.
Venue
Cognitive Science
Publisher
Wiley
Published
1988-04
Volume
12
Issue
2
Pages
139-175
ISSN
  • 0364-0213 (ISSN-L)
  • 1551-6709
OpenAlex
W2135241964
Cited by
403
References
19
FWCI
14.50
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Processes of Scientific Discovery: The Strategy of Experimentation. https://app.cochat.ai/papers/10.1207/s15516709cog1202_1
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Kulkarni, D., & Simon, H. A. (1988). The Processes of Scientific Discovery: The Strategy of Experimentation. Cognitive Science. https://doi.org/10.1207/s15516709cog1202_1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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